Standard name Systematic name Name description Description
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex Catalytic subunit of class II HDA1 histone deacetylase complex; role in azole resistance via Hsp90p, and in heat shock response; Hda1p interacts with Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation; the HDA1 histone deacetylase complex regulates aging through trehalose metabolism
Visualize the interactome of HDA1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.102 0.085 NaN
Nucleolus 0.120 0.085 NaN
Nucleus 0.914 0.918 0.967

GFP localization & abundance

GFP localization GFP abundance
nucleus 3050

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HDA1 7 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 15 5 10 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Enhancement, Dosage Lethality, Dosage Lethality, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 10 2 5 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 10 2 5 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 10 4 4 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Dosage Growth Defect, Phenotypic Suppression, Synthetic Rescue
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 8 2 6 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 7 3 5 Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 7 3 5 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality, Dosage Lethality, Negative Genetic, Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 7 2 5 Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 7 4 4 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression, Positive Genetic, Synthetic Rescue
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 7 4 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue, Positive Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex physical 6 3 4 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex physical 6 3 4 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 5 3 5 Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 5 3 4 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Rescue, Synthetic Rescue
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 5 3 3 Negative Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 5 3 3 Synthetic Rescue, Synthetic Rescue, Dosage Lethality, Dosage Lethality, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 5 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 4 3 4 Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 4 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex physical 4 3 3 Two-hybrid, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 4 3 3 Dosage Lethality, Dosage Lethality, Positive Genetic, Synthetic Rescue
ERG3 YLR056W C-5 sterol desaturase genetic 4 3 3 Phenotypic Suppression, Phenotypic Enhancement, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 4 2 3 Negative Genetic, Synthetic Rescue, Synthetic Rescue, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 4 2 3 Negative Genetic, Synthetic Rescue, Synthetic Rescue, Negative Genetic
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 4 2 3 Positive Genetic, Positive Genetic, Synthetic Rescue, Positive Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
HCM1 YCR065W Forkhead transcription factor genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 4 2 Synthetic Rescue, Phenotypic Enhancement, Dosage Growth Defect, Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 4 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic, Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 4 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 3 3 Phenotypic Suppression, Synthetic Rescue, Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 3 2 3 Positive Genetic, Synthetic Rescue, Positive Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 3 2 Synthetic Rescue, Phenotypic Enhancement, Phenotypic Suppression
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
HHT1 YBR010W Histone H3 genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 3 2 2 Phenotypic Enhancement, Dosage Lethality, Dosage Lethality
SWC5 YBR231C Component of the SWR1 complex genetic 3 2 2 Negative Genetic, Synthetic Rescue, Synthetic Rescue
YPT6 YLR262C Rab family GTPase genetic 3 2 2 Negative Genetic, Dosage Lethality, Dosage Lethality
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
STP22 YCL008C Component of the ESCRT-I complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Rescue
SWI6 YLR182W Transcription cofactor genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
VPS25 YJR102C Component of the ESCRT-II complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 3 2 2 Synthetic Rescue, Dosage Lethality, Dosage Lethality
SLA1 YBL007C Cytoskeletal protein binding protein genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 3 2 2 Dosage Lethality, Dosage Lethality, Positive Genetic
SDS22 YKL193C Regulatory subunit of the type 1 protein phosphatase (PP1) Glc7p genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 3 2 2 Dosage Lethality, Dosage Lethality, Positive Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 2 2 Synthetic Rescue, Dosage Lethality, Dosage Lethality
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 3 2 2 Negative Genetic, Dosage Lethality, Dosage Lethality
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 2 2 Positive Genetic, Synthetic Rescue, Synthetic Rescue
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 3 2 2 Negative Genetic, Synthetic Rescue, Synthetic Rescue
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 3 2 2 Dosage Lethality, Dosage Lethality, Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex genetic 3 1 2 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
RPP2B YDR382W Ribosomal protein P2 beta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LEA1 YPL213W Component of U2 snRNP complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AVO2 YMR068W Component of a complex containing the Tor2p kinase and other proteins genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 2 2 Synthetic Growth Defect, Dosage Lethality
BNI1 YNL271C Formin genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 2 2 2 Reconstituted Complex, Co-localization
HTA1 YDR225W Histone H2A genetic 2 2 2 Synthetic Rescue, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 2 2 2 Negative Genetic, Synthetic Rescue
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 2 2 Positive Genetic, Synthetic Rescue
SNF1 YDR477W AMP-activated S/T protein kinase genetic 2 2 2 Phenotypic Enhancement, Synthetic Rescue
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 2 2 2 Negative Genetic, Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Positive Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
YLR363W-A YLR363W-A Protein of unknown function genetic 2 2 2 Positive Genetic, Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 2 2 2 Negative Genetic, Phenotypic Enhancement
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Negative Genetic, Dosage Growth Defect
ADA2 YDR448W Transcription coactivator genetic 2 2 2 Positive Genetic, Synthetic Rescue
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 2 2 2 Synthetic Rescue, Positive Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Synthetic Rescue, Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 2 2 2 Synthetic Lethality, Positive Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Negative Genetic, Negative Genetic
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 2 1 2 Negative Genetic, Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 2 1 2 Positive Genetic, Positive Genetic
MSH2 YOL090W Protein that binds to DNA mismatches physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ physical 2 1 2 Biochemical Activity, Biochemical Activity
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 2 1 2 Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 2 1 2 Negative Genetic, Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 2 1 2 Negative Genetic, Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 2 1 2 Negative Genetic, Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 2 1 2 Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 2 1 2 Positive Genetic, Positive Genetic
UBP14 YBR058C Ubiquitin-specific protease genetic 2 1 2 Negative Genetic, Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 2 1 2 Negative Genetic, Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 2 1 2 Negative Genetic, Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Positive Genetic, Positive Genetic
ILM1 YJR118C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 1 2 Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
PYC1 YGL062W Pyruvate carboxylase isoform genetic 2 1 2 Negative Genetic, Negative Genetic
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 2 1 2 Negative Genetic, Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 2 1 2 Negative Genetic, Negative Genetic
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase genetic 2 1 2 Negative Genetic, Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 2 1 2 Negative Genetic, Negative Genetic
GZF3 YJL110C GATA zinc finger protein physical 2 1 2 Two-hybrid, Two-hybrid
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 2 1 2 Positive Genetic, Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 2 1 2 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 2 Positive Genetic, Positive Genetic
BDF1 YLR399C BET family transcriptional regulator regulation 2 2 1 chromatin immunoprecipitation evidence, quantitative reverse transcription polymerase chain reaction evidence
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation regulation 2 2 1 chromatin immunoprecipitation evidence, quantitative reverse transcription polymerase chain reaction evidence
BDF1 YLR399C BET family transcriptional regulator genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 2 2 1 Reconstituted Complex, Two-hybrid
PLC1 YPL268W Phospholipase C genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
AIM25 YJR100C Mitochondria protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
AMN1 YBR158W Modulator of cell separation and mitotic exit genetic 2 1 1 Dosage Lethality, Dosage Lethality
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
APL1 YJR005W Beta-adaptin genetic 2 1 1 Negative Genetic, Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
IKI3 YLR384C Subunit of Elongator complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ISM1 YPL040C Mitochondrial isoleucyl-tRNA synthetase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LIP2 YLR239C Lipoyl ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MEF1 YLR069C Mitochondrial elongation factor involved in translational elongation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
MSK1 YNL073W Mitochondrial lysine-tRNA synthetase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PEP5 YMR231W Histone E3 ligase, component of CORVET membrane tethering complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
PPR1 YLR014C Zinc finger transcription factor genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPL24A YGL031C Ribosomal 60S subunit protein L24A genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SNF8 YPL002C Component of the ESCRT-II complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TRM7 YBR061C 2'-O-ribose methyltransferase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS20 YMR077C Myristoylated subunit of the ESCRT-III complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS33 YLR396C ATP-binding protein that is a subunit of the HOPS and CORVET complexes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
VPS36 YLR417W Component of the ESCRT-II complex genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
TDA5 YLR426W Putative protein of unknown function genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RHB1 YCR027C Putative Rheb-related GTPase genetic 2 1 1 Negative Genetic, Negative Genetic
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme genetic 2 1 1 Negative Genetic, Negative Genetic
MET12 YPL023C Protein with MTHFR activity in vitro genetic 2 1 1 Negative Genetic, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 2 1 1 Dosage Lethality, Dosage Lethality
PKC1 YBL105C Protein serine/threonine kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
MLC1 YGL106W Essential light chain for Myo1p genetic 2 1 1 Dosage Lethality, Dosage Lethality
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
YPK1 YKL126W S/T protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 2 1 1 Dosage Lethality, Dosage Lethality
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 2 1 1 Dosage Lethality, Dosage Lethality
PRM1 YNL279W Pheromone-regulated multispanning membrane protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 2 1 1 Dosage Lethality, Dosage Lethality
YRM1 YOR172W Zinc finger transcription factor involved in multidrug resistance genetic 2 1 1 Dosage Lethality, Dosage Lethality
UPC2 YDR213W Sterol regulatory element binding protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 2 1 1 Dosage Lethality, Dosage Lethality
RME1 YGR044C Zinc finger protein involved in control of meiosis genetic 2 1 1 Dosage Lethality, Dosage Lethality
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor genetic 2 1 1 Dosage Lethality, Dosage Lethality
NHP6B YBR089C-A High-mobility group (HMG) protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
RSC30 YHR056C Component of the RSC chromatin remodeling complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 1 1 Dosage Lethality, Dosage Lethality
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 2 1 1 Dosage Lethality, Dosage Lethality
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin genetic 2 1 1 Dosage Lethality, Dosage Lethality
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 2 1 1 Dosage Lethality, Dosage Lethality
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
MCM6 YGL201C Protein involved in DNA replication genetic 2 1 1 Dosage Lethality, Dosage Lethality
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
TPO2 YGR138C Polyamine transporter of the major facilitator superfamily genetic 2 1 1 Dosage Lethality, Dosage Lethality
TAT2 YOL020W High affinity tryptophan and tyrosine permease genetic 2 1 1 Dosage Lethality, Dosage Lethality
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 2 1 1 Dosage Lethality, Dosage Lethality
SMY2 YBR172C GYF domain protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 2 1 1 Dosage Lethality, Dosage Lethality
SEC17 YBL050W Alpha-SNAP cochaperone genetic 2 1 1 Dosage Lethality, Dosage Lethality
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 2 1 1 Dosage Lethality, Dosage Lethality
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 1 1 Dosage Lethality, Dosage Lethality
YPT7 YML001W Rab family GTPase genetic 2 1 1 Dosage Lethality, Dosage Lethality
SSO1 YPL232W Plasma membrane t-SNARE genetic 2 1 1 Dosage Lethality, Dosage Lethality
TVP15 YDR100W Integral membrane protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 2 1 1 Dosage Lethality, Dosage Lethality
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 2 1 1 Dosage Lethality, Dosage Lethality
IFA38 YBR159W Microsomal beta-keto-reductase genetic 2 1 1 Dosage Lethality, Dosage Lethality
YEA6 YEL006W Mitochondrial NAD+ transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
HXT10 YFL011W Hexose transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
MIR1 YJR077C Mitochondrial phosphate carrier genetic 2 1 1 Dosage Lethality, Dosage Lethality
JEN1 YKL217W Monocarboxylate/proton symporter of the plasma membrane genetic 2 1 1 Dosage Lethality, Dosage Lethality
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
MDH1 YKL085W Mitochondrial malate dehydrogenase genetic 2 1 1 Dosage Lethality, Dosage Lethality
SYM1 YLR251W Protein required for ethanol metabolism genetic 2 1 1 Dosage Lethality, Dosage Lethality
YME2 YMR302C Integral inner mitochondrial membrane protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
ODC1 YPL134C Mitochondrial inner membrane transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
MBA1 YBR185C Membrane-associated mitochondrial ribosome receptor genetic 2 1 1 Dosage Lethality, Dosage Lethality
NDI1 YML120C NADH:ubiquinone oxidoreductase genetic 2 1 1 Dosage Lethality, Dosage Lethality
TPN1 YGL186C Plasma membrane pyridoxine (vitamin B6) transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
MPH3 YJR160C Alpha-glucoside permease genetic 2 1 1 Dosage Lethality, Dosage Lethality
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 2 1 1 Dosage Lethality, Dosage Lethality
MTR10 YOR160W Nuclear import receptor genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX25 YPL112C Peripheral peroxisomal membrane peroxin genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX13 YLR191W Peroxisomal importomer complex component genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX15 YOL044W Tail-anchored type II integral peroxisomal membrane protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX27 YOR193W Peripheral peroxisomal membrane protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 2 1 1 Dosage Lethality, Dosage Lethality
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis genetic 2 1 1 Dosage Lethality, Dosage Lethality
UBX3 YDL091C Clathrin-coated vesicle component, regulator of endocytosis genetic 2 1 1 Dosage Lethality, Dosage Lethality
HRT3 YLR097C Putative SCF-ubiquitin ligase F-box protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions genetic 2 1 1 Dosage Lethality, Dosage Lethality
UFO1 YML088W F-box receptor protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
HSP42 YDR171W Small heat shock protein (sHSP) with chaperone activity genetic 2 1 1 Dosage Lethality, Dosage Lethality
SSF2 YDR312W Protein required for ribosomal large subunit maturation genetic 2 1 1 Dosage Lethality, Dosage Lethality
PUS4 YNL292W Pseudouridine synthase genetic 2 1 1 Dosage Lethality, Dosage Lethality
RRP3 YHR065C Protein involved in rRNA processing genetic 2 1 1 Dosage Lethality, Dosage Lethality
MRPL49 YJL096W Mitochondrial ribosomal protein of the large subunit genetic 2 1 1 Dosage Lethality, Dosage Lethality
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes genetic 2 1 1 Dosage Lethality, Dosage Lethality
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 2 1 1 Dosage Lethality, Dosage Lethality
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 1 1 Dosage Lethality, Dosage Lethality
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) genetic 2 1 1 Dosage Lethality, Dosage Lethality
YFL040W YFL040W Putative transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 2 1 1 Dosage Lethality, Dosage Lethality
RIM4 YHL024W Putative RNA-binding protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
SCM4 YGR049W Mitochondrial outer membrane protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YDR249C YDR249C Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
PAM1 YDR251W Essential protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 2 1 1 Dosage Lethality, Dosage Lethality
SCY1 YGL083W Putative kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
YSC83 YHR017W Non-essential mitochondrial protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YIL055C YIL055C Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YIL089W YIL089W Protein of unknown function found in the ER and vacuole lumen genetic 2 1 1 Dosage Lethality, Dosage Lethality
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor genetic 2 1 1 Dosage Lethality, Dosage Lethality
JJJ2 YJL162C Protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YJL193W YJL193W Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YJR124C YJR124C Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
YOL029C YOL029C Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YPQ1 YOL092W Putative vacuolar membrane transporter for cationic amino acids genetic 2 1 1 Dosage Lethality, Dosage Lethality
YOR283W YOR283W Phosphatase with a broad substrate specificity genetic 2 1 1 Dosage Lethality, Dosage Lethality
TFB6 YOR352W Subunit of TFIIH complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
MUK1 YPL070W Guanine nucleotide exchange factor (GEF) genetic 2 1 1 Dosage Lethality, Dosage Lethality
YPL071C YPL071C Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
YPL245W YPL245W Putative protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
TMH18 YPR098C Mitochondrial protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
PHM7 YOL084W Protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
MNP1 YGL068W Mitochondrial ribosomal protein of the large subunit genetic 2 1 1 Dosage Lethality, Dosage Lethality
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Negative Genetic, Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 2 1 1 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 2 1 1 Negative Genetic, Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 2 1 1 Negative Genetic, Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 2 1 1 Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 2 1 1 Negative Genetic, Negative Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 2 1 1 Negative Genetic, Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ELP2 YGR200C Subunit of Elongator complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 2 1 1 Dosage Lethality, Dosage Lethality
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 2 1 1 Dosage Lethality, Dosage Lethality
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 2 1 1 Dosage Lethality, Dosage Lethality
END3 YNL084C EH domain-containing protein involved in endocytosis genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 2 1 1 Dosage Lethality, Dosage Lethality
BGL2 YGR282C Endo-beta-1,3-glucanase genetic 2 1 1 Dosage Lethality, Dosage Lethality
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase genetic 2 1 1 Dosage Lethality, Dosage Lethality
CDC53 YDL132W Cullin genetic 2 1 1 Negative Genetic, Negative Genetic
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 2 1 1 Dosage Lethality, Dosage Lethality
ACS2 YLR153C Acetyl-coA synthetase isoform genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 2 1 1 Dosage Lethality, Dosage Lethality
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 2 1 1 Dosage Lethality, Dosage Lethality
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 2 1 1 Dosage Lethality, Dosage Lethality
GRX5 YPL059W Glutathione-dependent oxidoreductase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GMH1 YKR030W Golgi membrane protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
ELP3 YPL086C Subunit of Elongator complex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ATG8 YBL078C Ub-like protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
CNM67 YNL225C Component of the spindle pole body outer plaque genetic 2 1 1 Dosage Lethality, Dosage Lethality
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 2 1 1 Dosage Lethality, Dosage Lethality
GIC1 YHR061C Rho-family GTPase interacting protein and Cdc42p effector genetic 2 1 1 Dosage Lethality, Dosage Lethality
ARK1 YNL020C Ser/Thr protein kinase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 2 1 1 Dosage Lethality, Dosage Lethality
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 2 1 1 Dosage Lethality, Dosage Lethality
EMP70 YLR083C Protein with a role in cellular adhesion and filamentous growth genetic 2 1 1 Dosage Lethality, Dosage Lethality
BUD22 YMR014W Protein required for rRNA maturation and ribosomal subunit biogenesis genetic 2 1 1 Dosage Lethality, Dosage Lethality
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 2 1 1 Dosage Lethality, Dosage Lethality
ERG2 YMR202W C-8 sterol isomerase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
ANT1 YPR128C Peroxisomal adenine nucleotide transporter genetic 2 1 1 Dosage Lethality, Dosage Lethality
AIM22 YJL046W Lipoate-protein ligase genetic 2 1 1 Negative Genetic, Negative Genetic
GTT3 YEL017W Protein of unknown function may be involved in glutathione metabolism genetic 2 1 1 Dosage Lethality, Dosage Lethality
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 2 1 1 Dosage Lethality, Dosage Lethality
ECM22 YLR228C Sterol regulatory element binding protein genetic 2 1 1 Dosage Lethality, Dosage Lethality
ENA5 YDR038C Protein with similarity to P-type ATPase sodium pumps genetic 2 1 1 Dosage Lethality, Dosage Lethality
DCW1 YKL046C Putative mannosidase genetic 2 1 1 Dosage Lethality, Dosage Lethality
CCW12 YLR110C Cell wall mannoprotein genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CUR1 YPR158W Sorting factor, central regulator of spatial protein quality control genetic 2 1 1 Dosage Lethality, Dosage Lethality
ATG41 YPL250C Protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
ARN1 YHL040C ARN family transporter for siderophore-iron chelates genetic 2 1 1 Dosage Lethality, Dosage Lethality
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
AIM19 YIL087C Protein of unknown function genetic 2 1 1 Dosage Lethality, Dosage Lethality
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
BNA4 YBL098W Kynurenine 3-monooxygenase genetic 2 1 1 Dosage Lethality, Dosage Lethality
FAT3 YKL187C Protein required for fatty acid uptake genetic 2 1 1 Dosage Lethality, Dosage Lethality
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 1 1 1 Positive Genetic
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
DBP9 YLR276C DEAD-box protein required for 27S rRNA processing genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
ARC15 YIL062C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Rescue
BEM1 YBR200W Protein containing SH3-domains genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC36 YDL165W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) physical 1 1 1 Two-hybrid
OCT1 YKL134C Mitochondrial intermediate peptidase physical 1 1 1 Affinity Capture-MS
RUP1 YOR138C Protein that regulates ubiquitination of Rsp5p physical 1 1 1 Affinity Capture-MS
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase physical 1 1 1 Two-hybrid
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Two-hybrid
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Synthetic Rescue
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Two-hybrid
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
HTB1 YDR224C Histone H2B physical 1 1 1 Reconstituted Complex
HTB1 YDR224C Histone H2B genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A physical 1 1 1 Reconstituted Complex
HHT1 YBR010W Histone H3 physical 1 1 1 Reconstituted Complex
HHF1 YBR009C Histone H4 physical 1 1 1 Reconstituted Complex
HHF1 YBR009C Histone H4 genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Positive Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 1 1 1 Affinity Capture-Western
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
SIR3 YLR442C Silencing protein genetic 1 1 1 Phenotypic Enhancement
RSC4 YKR008W Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
SQS1 YNL224C Protein that stimulates the ATPase and helicase activities of Prp43p genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
TEX1 YNL253W Protein involved in mRNA export genetic 1 1 1 Negative Genetic
RAD30 YDR419W DNA polymerase eta genetic 1 1 1 Negative Genetic
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
IRC20 YLR247C E3 ubiquitin ligase and putative helicase genetic 1 1 1 Positive Genetic
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Positive Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Positive Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
OST2 YOR103C Epsilon subunit of the oligosaccharyltransferase complex genetic 1 1 1 Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RRP15 YPR143W Nucleolar protein genetic 1 1 1 Negative Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Synthetic Rescue
TRA1 YHR099W Subunit of SAGA and NuA4 histone acetyltransferase complexes genetic 1 1 1 Synthetic Growth Defect
TUB3 YML124C Alpha-tubulin genetic 1 1 1 Synthetic Rescue
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Rescue
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Synthetic Rescue
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Synthetic Rescue
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Synthetic Rescue
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 1 1 1 Synthetic Rescue
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Synthetic Rescue
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Synthetic Rescue
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Synthetic Rescue
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
HIS6 YIL020C Enzyme that catalyzes the fourth step in the histidine pathway genetic 1 1 1 Synthetic Rescue
IST3 YIR005W Component of the U2 snRNP genetic 1 1 1 Synthetic Rescue
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 1 1 1 Synthetic Rescue
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Synthetic Rescue
RPB4 YJL140W RNA polymerase II subunit B32 genetic 1 1 1 Synthetic Rescue
SAC3 YDR159W mRNA export factor genetic 1 1 1 Synthetic Rescue
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Synthetic Rescue
ISA1 YLL027W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Synthetic Rescue
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Rescue
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Synthetic Rescue
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase genetic 1 1 1 Synthetic Rescue
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Synthetic Rescue
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Phenotypic Suppression
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Positive Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Phenotypic Enhancement
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Phenotypic Suppression
IES6 YEL044W Component of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Positive Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 1 1 1 Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Positive Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Positive Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Positive Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Positive Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Positive Genetic
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Positive Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Positive Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Positive Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Positive Genetic
YBR196C-A YBR196C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Positive Genetic
YBR220C YBR220C Putative protein of unknown function genetic 1 1 1 Positive Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 1 1 1 Positive Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Positive Genetic
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Positive Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Positive Genetic
QCR9 YGR183C Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Positive Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Positive Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Positive Genetic
NEL1 YHR035W Activator of Sar1p GTPase activity genetic 1 1 1 Positive Genetic
YHR212W-A YHR212W-A Pseudogenic fragment with similarity to flocculins genetic 1 1 1 Positive Genetic
PET191 YJR034W Protein required for assembly of cytochrome c oxidase genetic 1 1 1 Positive Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
YLR159C-A YLR159C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Positive Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Positive Genetic
IMP2 YMR035W Catalytic subunit of mitochondrial inner membrane peptidase complex genetic 1 1 1 Positive Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Positive Genetic
PIN2 YOR104W Exomer-dependent cargo protein genetic 1 1 1 Positive Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Positive Genetic
PBI1 YPL272C Putative protein of unknown function genetic 1 1 1 Positive Genetic
TEF1 YPR080W Translational elongation factor EF-1 alpha genetic 1 1 1 Positive Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RRN3 YKL125W Protein required for transcription of rDNA by RNA polymerase I genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Negative Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RRS1 YOR294W Essential protein that binds ribosomal protein L11 genetic 1 1 1 Negative Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Negative Genetic
TAF3 YPL011C TFIID subunit (47 kDa) genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
IPL1 YPL209C Aurora kinase of chromosomal passenger complex genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
ORC1 YML065W Largest subunit of the origin recognition complex genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
SWH1 YAR042W Protein similar to mammalian oxysterol-binding protein genetic 1 1 1 Negative Genetic
YAR066W YAR066W Putative GPI protein genetic 1 1 1 Negative Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
YBR096W YBR096W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Negative Genetic
VPS54 YDR027C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
MRX14 YDR115W Putative mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
YEA4 YEL004W Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
RPO41 YFL036W Mitochondrial RNA polymerase genetic 1 1 1 Negative Genetic
MRX20 YFR045W Putative mitochondrial transport protein genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 1 1 1 Negative Genetic
PDC6 YGR087C Minor isoform of pyruvate decarboxylase genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
OTU2 YHL013C Protein of unknown function genetic 1 1 1 Negative Genetic
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
SPO22 YIL073C Meiosis-specific protein essential for chromosome synapsis genetic 1 1 1 Negative Genetic
LCB3 YJL134W Long-chain base-1-phosphate phosphatase genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
YKL183C-A YKL183C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TVP38 YKR088C Integral membrane protein genetic 1 1 1 Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Negative Genetic
PUT1 YLR142W Proline oxidase genetic 1 1 1 Negative Genetic
TFS1 YLR178C Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p) genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
YLR464W YLR464W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YML037C YML037C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
YMR084W YMR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PRM15 YMR278W Phosphoribomutase genetic 1 1 1 Negative Genetic
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
KIP1 YBL063W Kinesin-related motor protein genetic 1 1 1 Negative Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 1 1 1 Negative Genetic
YMC2 YBR104W Putative mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
PEX6 YNL329C AAA-peroxin genetic 1 1 1 Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Negative Genetic
YOL057W YOL057W Dipeptidyl-peptidase III genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
RAX1 YOR301W Protein involved in establishing bud site selection genetic 1 1 1 Negative Genetic
VPS28 YPL065W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Positive Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Positive Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Positive Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 1 1 1 Phenotypic Suppression
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase genetic 1 1 1 Phenotypic Suppression
HHT2 YNL031C Histone H3 genetic 1 1 1 Phenotypic Suppression
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Phenotypic Suppression
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Rescue
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Positive Genetic
CSN9 YDR179C Subunit of the Cop9 signalosome genetic 1 1 1 Positive Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Synthetic Rescue
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 1 1 1 Positive Genetic
CIR2 YOR356W Putative ortholog of human ETF-dH genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor genetic 1 1 1 Phenotypic Enhancement
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Negative Genetic
DDC1 YPL194W DNA damage checkpoint protein genetic 1 1 1 Negative Genetic
CAT5 YOR125C Protein required for ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Positive Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
CTF13 YMR094W Subunit of the CBF3 complex genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
CCE1 YKL011C Mitochondrial cruciform cutting endonuclease genetic 1 1 1 Positive Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Synthetic Rescue
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Positive Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation genetic 1 1 1 Negative Genetic
GLG2 YJL137C Glycogenin glucosyltransferase genetic 1 1 1 Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Negative Genetic
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Synthetic Growth Defect
CDC43 YGL155W Beta subunit of geranylgeranyltransferase type I genetic 1 1 1 Negative Genetic
CPR2 YHR057C Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Positive Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
GNP1 YDR508C Broad specificity amino acid permease genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Positive Genetic
COQ5 YML110C 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase genetic 1 1 1 Positive Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
ALF1 YNL148C Alpha-tubulin folding protein genetic 1 1 1 Synthetic Rescue
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Synthetic Rescue
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Positive Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Positive Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 1 1 1 Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
EMC1 YCL045C Member of conserved endoplasmic reticulum membrane complex genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Negative Genetic
DAL80 YKR034W Negative regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 Two-hybrid
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Phenotypic Enhancement
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Negative Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
GTB1 YDR221W Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p genetic 1 1 1 Negative Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
CBS1 YDL069C Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Positive Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Positive Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Positive Genetic
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Positive Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 1 1 1 Positive Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Positive Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
BRR6 YGL247W Essential nuclear envelope integral membrane protein genetic 1 1 1 Synthetic Rescue
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
AVL9 YLR114C Conserved protein involved in exocytic transport from the Golgi genetic 1 1 1 Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Positive Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
DNF3 YMR162C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
EMC10 YDR056C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Positive Genetic
AFG1 YEL052W Protein that may act as a chaperone for cytochrome c oxidase subunits genetic 1 1 1 Negative Genetic
ADY2 YCR010C Acetate transporter required for normal sporulation genetic 1 1 1 Negative Genetic
CIN10 YDR387C Putative transporter genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Positive Genetic
ALP1 YNL270C Arginine transporter genetic 1 1 1 Positive Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
GRE1 YPL223C Hydrophilin essential in desiccation-rehydration process genetic 1 1 1 Negative Genetic