| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
physical |
7 |
4 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Two-hybrid |
| TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
7 |
3 |
4 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
6 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
6 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
5 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
| SNX4 |
YJL036W |
Sorting nexin |
genetic |
5 |
2 |
4 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
| GET2 |
YER083C |
Subunit of the GET complex |
genetic |
5 |
3 |
3 |
Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
| ATG8 |
YBL078C |
Ub-like protein |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
5 |
2 |
3 |
Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic |
| VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
| ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
4 |
2 |
3 |
Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MRL1 |
YPR079W |
Membrane protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
4 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| MSC1 |
YML128C |
Protein of unknown function |
genetic |
4 |
2 |
2 |
Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression |
| COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SGM1 |
YJR134C |
Protein of unknown function |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VAC14 |
YLR386W |
Enzyme regulator |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
| GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| SFT2 |
YBL102W |
Tetra-spanning membrane protein found mostly in the late Golgi |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VAM10 |
YOR068C |
Protein involved in vacuole morphogenesis |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| KEX1 |
YGL203C |
Cell death protease essential for hypochlorite-induced apoptosis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Negative Genetic |
| STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| IMH1 |
YLR309C |
Protein involved in vesicular transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PIL1 |
YGR086C |
Eisosome core component |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
| COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ELP6 |
YMR312W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PHO80 |
YOL001W |
Cyclin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TRS33 |
YOR115C |
Core component of TRAPP complexes I, II and IV |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
3 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| TMS1 |
YDR105C |
Vacuolar membrane protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Phenotypic Enhancement |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
| SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| DCR2 |
YLR361C |
Protein phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
1 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence |
| APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ENV7 |
YPL236C |
Vacuolar membrane protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| IKI1 |
YHR187W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PDR17 |
YNL264C |
Phosphatidylinositol transfer protein (PITP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| OLE1 |
YGL055W |
Delta(9) fatty acid desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ENT4 |
YLL038C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| TMA22 |
YJR014W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| VNX1 |
YNL321W |
Calcium/H+ antiporter localized to the endoplasmic reticulum membrane |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| YPT1 |
YFL038C |
Rab family GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| KTR3 |
YBR205W |
Putative alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FAR7 |
YFR008W |
Protein involved in recovery from pheromone-induced cell cycle arrest |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SEC4 |
YFL005W |
Rab family GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SEC8 |
YPR055W |
Essential 121 kDa subunit of the exocyst complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
| RCE1 |
YMR274C |
Type II CAAX prenyl protease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SOP4 |
YJL192C |
ER-membrane protein |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IML1 |
YJR138W |
GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL6 |
YMR091C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNI1 |
YNL271C |
Formin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR345W |
YLR345W |
Similar to 6-phosphofructo-2-kinase enzymes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR035C-A |
YAR035C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER079W |
YER079W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER084W |
YER084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLL056C |
YLL056C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR285C-A |
YLR285C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR155W |
YMR155W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNL146W |
YNL146W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL013W-A |
YOL013W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL161W |
YIL161W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR210W |
YDR210W |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJL118W |
YJL118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIP1 |
YDR422C |
One of three alternate beta-subunits of the Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEN54 |
YPL083C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FLC2 |
YAL053W |
Putative calcium channel involved in calcium release under hypotonic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
physical |
1 |
1 |
1 |
Two-hybrid |
| PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARE2 |
YNR019W |
Acyl-CoA:sterol acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| MGT1 |
YDL200C |
DNA repair methyltransferase (6-O-methylguanine-DNA methylase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GNA1 |
YFL017C |
Glucosamine-6-phosphate acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPO1 |
YNL012W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
physical |
1 |
1 |
1 |
Two-hybrid |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
physical |
1 |
1 |
1 |
Two-hybrid |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELP4 |
YPL101W |
Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPT1 |
YNL130C |
Cholinephosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOP2 |
YGL033W |
Meiosis-specific protein that localizes to chromosomes |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REC102 |
YLR329W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STP22 |
YCL008C |
Component of the ESCRT-I complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BUD6 |
YLR319C |
Actin- and formin-interacting protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNF3 |
YDL194W |
Plasma membrane low glucose sensor, regulates glucose transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCW4 |
YGR279C |
Cell wall protein with similarity to glucanases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DPM1 |
YPR183W |
Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ADI1 |
YMR009W |
Acireductone dioxygenease involved in methionine salvage pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GTA1 |
YEL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
| MIG2 |
YGL209W |
Zinc finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FCF2 |
YLR051C |
Nucleolar protein involved in the early steps of 35S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| AQY3 |
YFL054C |
Putative channel-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS31 |
YDR472W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EGH1 |
YIR007W |
Steryl-beta-glucosidase with broad specificity for aglycones |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OSM1 |
YJR051W |
Fumarate reductase, catalyzes the reduction of fumarate to succinate |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| OTU2 |
YHL013C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RGS2 |
YOR107W |
Negative regulator of glucose-induced cAMP signaling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS5 |
YOR069W |
Nexin-1 homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RHO3 |
YIL118W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOK2 |
YMR016C |
Nuclear protein that negatively regulates pseudohyphal differentiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| THI80 |
YOR143C |
Thiamine pyrophosphokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAH11 |
YJR046W |
DNA replication licensing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDS1 |
YBR033W |
Putative zinc cluster protein, predicted to be a transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EMA19 |
YLR050C |
Integral ER membrane protein involved in protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAI3 |
YMR174C |
Cytoplasmic proteinase A (Pep4p) inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET5 |
YJR137C |
Sulfite reductase beta subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DLT1 |
YMR126C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERD2 |
YBL040C |
HDEL receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCV1 |
YDR019C |
T subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECT1 |
YGR007W |
Ethanolamine-phosphate cytidylyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT1 |
YLR142W |
Proline oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAM41 |
YGR046W |
Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPA10 |
YLR307C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPS2 |
YDR522C |
Protein expressed during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOM6 |
YOR045W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO24 |
YPR036W-A |
Small (67 amino acids) protein involved in sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNL2 |
YLR057W |
Putative mannosidase involved in ER-associated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPS4 |
YOR313C |
Protein whose expression is induced during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD1 |
YEL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
