Standard name Systematic name Name description Description
HOP2 YGL033W Meiosis-specific protein that localizes to chromosomes Meiosis-specific protein that localizes to chromosomes; prevents synapsis between nonhomologous chromosomes and ensures synapsis between homologs; forms complex with Mnd1p to promote homolog pairing and meiotic double-strand break repair; heterodimer of Hop2p-Mnd1p stimulates the Dmc1p-mediated strand invasion
Visualize the interactome of HOP2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HOP2 0 2 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MND1 YGL183C Protein required for recombination and meiotic nuclear division physical 5 4 5 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Co-purification
MEK1 YOR351C Meiosis-specific serine/threonine protein kinase genetic 2 2 2 Dosage Rescue, Negative Genetic
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 2 2 1 Synthetic Lethality, Phenotypic Suppression
LDO16 YMR148W Protein of unknown function with possible role in spore wall assembly genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
EMC10 YDR056C Putative protein of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC73 YLR418C Component of the Paf1p complex regulation 1 1 1 DNA to cDNA expression microarray evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AFT1 YGL071W Transcription factor involved in iron utilization and homeostasis regulation 1 1 1 DNA to cDNA expression microarray evidence
MOT3 YMR070W Transcriptional repressor, activator regulation 1 1 1 DNA to cDNA expression microarray evidence
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Negative Genetic
FPR3 YML074C Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Phenotypic Suppression
DMC1 YER179W Meiosis-specific recombinase required for double-strand break repair genetic 1 1 1 Synthetic Rescue
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Negative Genetic
BNA5 YLR231C Kynureninase genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CLB1 YGR108W B-type cyclin involved in cell cycle progression genetic 1 1 1 Dosage Rescue
MND1 YGL183C Protein required for recombination and meiotic nuclear division genetic 1 1 1 Dosage Rescue
NUM1 YDR150W Protein required for nuclear migration physical 1 1 1 Two-hybrid
RAD51 YER095W Strand exchange protein genetic 1 1 1 Dosage Rescue
RED1 YLR263W Protein component of the synaptonemal complex axial elements genetic 1 1 1 Dosage Rescue
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Synthetic Growth Defect
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Phenotypic Suppression
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Synthetic Rescue
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Phenotypic Suppression
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
ZIP2 YGL249W Meiosis-specific protein genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
SMM1 YNR015W Dihydrouridine synthase genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
MUM3 YOR298W Protein of unknown function involved in outer spore wall organization genetic 1 1 1 Negative Genetic
KAP120 YPL125W Karyopherin responsible for the nuclear import of Rpf1p genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
BIL1 YOR304C-A Protein that binds Bud6p and has a role in actin cable assembly genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
HED1 YDR014W-A Meiosis-specific protein genetic 1 1 1 Synthetic Rescue
FLO10 YKR102W Member of the FLO family of cell wall flocculation proteins genetic 1 1 1 Negative Genetic