SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
physical |
9 |
4 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
physical |
8 |
1 |
6 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
7 |
3 |
5 |
Dosage Rescue, Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
physical |
6 |
3 |
5 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Two-hybrid |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
genetic |
6 |
3 |
4 |
Dosage Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
6 |
3 |
4 |
Synthetic Lethality, Synthetic Rescue, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
physical |
6 |
3 |
3 |
Biochemical Activity, Reconstituted Complex, Reconstituted Complex, Biochemical Activity, Reconstituted Complex, Affinity Capture-Western |
SPC2 |
YML055W |
Subunit of signal peptidase complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Positive Genetic, Negative Genetic, Negative Genetic |
ROT2 |
YBR229C |
Glucosidase II catalytic subunit |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Positive Genetic, Negative Genetic, Negative Genetic |
CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
4 |
3 |
3 |
Synthetic Growth Defect, Positive Genetic, Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic |
PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
SPC1 |
YJR010C-A |
Subunit of the signal peptidase complex (SPC) |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
JEM1 |
YJL073W |
DnaJ-like chaperone required for nuclear membrane fusion during mating |
physical |
3 |
2 |
2 |
Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
3 |
2 |
2 |
Dosage Rescue, Negative Genetic, Negative Genetic |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
2 |
2 |
2 |
Co-purification, Two-hybrid |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
MYO1 |
YHR023W |
Type II myosin heavy chain |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SEC11 |
YIR022W |
18kDa catalytic subunit of the Signal Peptidase Complex (SPC) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
OST5 |
YGL226C-A |
Zeta subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
LCL2 |
YLR104W |
Putative protein of unknown function |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
JEM1 |
YJL073W |
DnaJ-like chaperone required for nuclear membrane fusion during mating |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
physical |
2 |
2 |
2 |
Co-fractionation, Affinity Capture-Western |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
CNE1 |
YAL058W |
Calnexin |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
ERJ5 |
YFR041C |
Type I membrane protein with a J domain |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
YOS9 |
YDR057W |
ER quality-control lectin |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
PEP7 |
YDR323C |
Adaptor protein involved in vesicle-mediated vacuolar protein sorting |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
ACL4 |
YDR161W |
Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GEA1 |
YJR031C |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SPC3 |
YLR066W |
Subunit of signal peptidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YJR015W |
YJR015W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MSL5 |
YLR116W |
Component of commitment complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NPR3 |
YHL023C |
Subunit of the Iml1p/SEACIT complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWM2 |
YNR004W |
Protein with a role in snRNA and snoRNA cap trimethylation |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SUA7 |
YPR086W |
Transcription factor TFIIB |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMW1 |
YNL313C |
Essential conserved protein with a role in cell wall integrity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERP1 |
YAR002C-A |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERP2 |
YAL007C |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV25 |
YML012W |
Member of the p24 family involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTO1 |
YCR015C |
Protein required for cold tolerance |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HHF1 |
YBR009C |
Histone H4 |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTB2 |
YBL002W |
Histone H2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM30 |
YLR436C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FLC2 |
YAL053W |
Putative calcium channel involved in calcium release under hypotonic |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP4 |
YPL078C |
Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Two-hybrid |
FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
AGX1 |
YFL030W |
Alanine:glyoxylate aminotransferase (AGT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAS1 |
YJL149W |
Putative SCF ubiquitin ligase F-box protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP5 |
YPL249C |
GTPase-activating protein (GAP) for yeast Rab family members |
physical |
1 |
1 |
1 |
Two-hybrid |
ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBP6 |
YBR120C |
Mitochondrial protein required for translation of the COB mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
BOP2 |
YLR267W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPA1 |
YOR303W |
Small subunit of carbamoyl phosphate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
1 |
1 |
1 |
Positive Genetic |
APE3 |
YBR286W |
Vacuolar aminopeptidase Y |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Positive Genetic |
DID4 |
YKL002W |
Class E Vps protein of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAR3 |
YMR052W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIS1 |
YIL065C |
Protein involved in mitochondrial fission and peroxisome abundance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALF1 |
YNL148C |
Alpha-tubulin folding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ELO3 |
YLR372W |
Elongase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOP2 |
YGL033W |
Meiosis-specific protein that localizes to chromosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
GOS1 |
YHL031C |
v-SNARE protein involved in Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TGL5 |
YOR081C |
Bifunctional triacylglycerol lipase and LPA acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LYS9 |
YNR050C |
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KRE6 |
YPR159W |
Glucosyl hydrolase required for beta-1,6-glucan biosynthesis |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KRE6 |
YPR159W |
Glucosyl hydrolase required for beta-1,6-glucan biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
physical |
1 |
1 |
1 |
PCA |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
PCA |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NBP1 |
YLR457C |
Spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIC60 |
YKR016W |
Component of the MICOS complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPC3 |
YLR066W |
Subunit of signal peptidase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
physical |
1 |
1 |
1 |
Two-hybrid |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
physical |
1 |
1 |
1 |
Two-hybrid |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
physical |
1 |
1 |
1 |
Two-hybrid |
VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Two-hybrid |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
1 |
1 |
1 |
Two-hybrid |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
physical |
1 |
1 |
1 |
Two-hybrid |
TDA11 |
YHR159W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
physical |
1 |
1 |
1 |
Two-hybrid |
OM45 |
YIL136W |
Mitochondrial outer membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
1 |
1 |
1 |
Two-hybrid |
RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
physical |
1 |
1 |
1 |
Two-hybrid |
YKL050C |
YKL050C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
physical |
1 |
1 |
1 |
Two-hybrid |
VPS20 |
YMR077C |
Myristoylated subunit of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGM1 |
YOR211C |
Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p |
physical |
1 |
1 |
1 |
Two-hybrid |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCD5 |
YOR329C |
Protein required for normal actin organization and endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
SKS1 |
YPL026C |
Putative serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Two-hybrid |
YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Two-hybrid |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL216W |
YPL216W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PXA1 |
YPL147W |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p |
physical |
1 |
1 |
1 |
PCA |
YBT1 |
YLL048C |
Transporter of the ATP-binding cassette (ABC) family |
physical |
1 |
1 |
1 |
PCA |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM22 |
YNL131W |
Component of the TOM (Translocase of Outer Membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MPD1 |
YOR288C |
Member of the protein disulfide isomerase (PDI) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS28 |
YPL065W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTT106 |
YNL206C |
Histone chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS3 |
YDR495C |
Component of CORVET membrane tethering complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PMT1 |
YDL095W |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI10 |
YOL032W |
Protein with a possible role in phospholipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSD2 |
YGR170W |
Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Positive Genetic |
VHR2 |
YER064C |
Non-essential nuclear protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMD4 |
YLR363C |
Protein that may be involved in nonsense-mediated mRNA decay |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MYG1 |
YER156C |
Protein involved in mitochondrial function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL068C |
YPL068C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
THI6 |
YPL214C |
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YML108W |
YML108W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOF2 |
YKR010C |
Protein required for rDNA silencing and mitotic rDNA condensation |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM1 |
YDR120C |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRM2 |
YIL037C |
Pheromone-regulated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTR2 |
YKR093W |
Integral membrane peptide transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RLF2 |
YPR018W |
Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPR084W |
YPR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR209C |
YMR209C |
Putative S-adenosylmethionine-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YBR137W |
YBR137W |
Protein with a role in ER delivery of tail-anchored membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
REX4 |
YOL080C |
Putative RNA exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SBH2 |
YER019C-A |
Ssh1p-Sss1p-Sbh2p complex component |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR287C |
YLR287C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
1 |
1 |
1 |
Positive Genetic |
NFT1 |
YKR103W |
Putative transporter of the MRP subfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRX20 |
YFR045W |
Putative mitochondrial transport protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTP1 |
YDL230W |
Phosphotyrosine-specific protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UME1 |
YPL139C |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGM1 |
YJR134C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPR063C |
YPR063C |
ER-localized protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
WSC4 |
YHL028W |
Endoplasmic reticulum (ER) membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
LOG1 |
YJL055W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHB17 |
YKR043C |
Sedoheptulose bisphosphatase involved in riboneogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
VTC4 |
YJL012C |
Vacuolar membrane polyphosphate polymerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM7 |
YBR061C |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRF1 |
YDL133W |
Regulator of phospholipase D (Spo14p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YET1 |
YKL065C |
Endoplasmic reticulum transmembrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIL055C |
YIL055C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSA4 |
YER103W |
Heat shock protein that is highly induced upon stress |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPE4 |
YLR146C |
Spermine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YIP3 |
YNL044W |
Protein localized to COPII vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC5 |
YDR128W |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN4 |
YKL201C |
Putative positive regulator of mannosylphosphate transferase Mnn6p |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN5 |
YJL186W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIR3 |
YIL011W |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNS1 |
YJR131W |
Alpha-1,2-mannosidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET18 |
YCR020C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Positive Genetic |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
1 |
1 |
1 |
Positive Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPT1 |
YGR123C |
Protein serine/threonine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR278C |
YLR278C |
Zinc-cluster protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Positive Genetic |
SED4 |
YCR067C |
Integral ER membrane protein that stimulates Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN9 |
YPL050C |
Subunit of Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TCD1 |
YHR003C |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
KEL1 |
YHR158C |
Protein required for proper cell fusion and cell morphology |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YFR018C |
YFR018C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHR078W |
YHR078W |
High osmolarity-regulated gene of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YUR1 |
YJL139C |
Mannosyltransferase involved in protein N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Positive Genetic |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Positive Genetic |
NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMP3 |
YOR149C |
Alpha 1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA6 |
YDR067C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAY1 |
YGR263C |
Sterol deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RLM1 |
YPL089C |
MADS-box transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYT1 |
YPR095C |
Guanine nucleotide exchange factor (GEF) for Arf proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL086C |
YBL086C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK32 |
YCR019W |
Protein necessary for stability of L-A dsRNA-containing particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPQ2 |
YDR352W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR524W-C |
YDR524W-C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
YFL065C |
YFL065C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR204C-A |
YGR204C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPX1 |
YHR201C |
Exopolyphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET18 |
YIL128W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PER33 |
YLR064W |
Protein that localizes to the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT11 |
YNL304W |
Rab GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR296W |
YOR296W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYK2 |
YOR347C |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL060C-A |
YPL060C-A |
TyA Gag protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
EMP47 |
YFL048C |
Integral membrane component of ER-derived COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV46 |
YAL042W |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BNR1 |
YIL159W |
Formin |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMA17 |
YIL029C |
Protein involved in targeting mitochondrial membrane protein precursor |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
physical |
1 |
1 |
1 |
Two-hybrid |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHT2 |
YNL031C |
Histone H3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV29 |
YGR284C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSV2 |
YGR223C |
Phosphatidylinositol 3,5-bisphosphate-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
DOM34 |
YNL001W |
Protein that facilitates ribosomal subunit dissociation |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC6 |
YLL014W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
HMG1 |
YML075C |
HMG-CoA reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Positive Genetic |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTB1 |
YDR221W |
Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAM1 |
YJR069C |
Nucleoside triphosphate pyrophosphohydrolase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUE1 |
YMR264W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCV3 |
YAL044C |
H subunit of the mitochondrial glycine decarboxylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRD1 |
YEL047C |
Soluble fumarate reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AHC2 |
YCR082W |
Component of the ADA histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AHC2 |
YCR082W |
Component of the ADA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI17 |
YDR434W |
Transmembrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Positive Genetic |
FYV6 |
YNL133C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUT1 |
YPL244C |
Protein with a role in UDP-galactose transport to the Golgi lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI12 |
YMR281W |
ER membrane protein involved in the second step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC4 |
YGL231C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ2 |
YNR041C |
Para hydroxybenzoate polyprenyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
ITR1 |
YDR497C |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
physical |
1 |
1 |
1 |
PCA |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
DFG10 |
YIL049W |
Probable polyprenol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC10 |
YDR056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRE4 |
YNR060W |
Ferric reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GSH2 |
YOL049W |
Glutathione synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATG22 |
YCL038C |
Vacuolar integral membrane protein required for efflux of amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERD2 |
YBL040C |
HDEL receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXT8 |
YJL214W |
Protein of unknown function with similarity to hexose transporters |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSS3 |
YOL159C |
Protein of unknown function, secreted when constitutively expressed |
genetic |
1 |
1 |
1 |
Positive Genetic |
GYP8 |
YFL027C |
GTPase-activating protein for yeast Rab family members |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASP3-3 |
YLR158C |
Cell-wall L-asparaginase II involved in asparagine catabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |