Standard name Systematic name Name description Description
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) Subunit VII of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain
Visualize the interactome of COX7
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Golgi 0.051 0.123 NaN
Mito 0.895 0.823 0.943
Vac/Vac Memb 0.127 0.201 0.057
Nuc Periphery NaN NaN 0.063
Nucleolus NaN NaN 0.052

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 639

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
COX7 1 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_0438 (ferrocytochrome-c:oxygen oxidoreductase)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COX1 Q0045 Subunit I of cytochrome c oxidase (Complex IV) physical 3 3 3 Co-fractionation, Reconstituted Complex, Affinity Capture-MS
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STR3 YGL184C Peroxisomal cystathionine beta-lyase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
ERS1 YCR075C Protein involved in cystine transport genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STF1 YDL130W-A Protein involved in regulation of the mitochondrial F1F0-ATP synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
STP2 YHR006W Transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
CNE1 YAL058W Calnexin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
COX2 Q0250 Subunit II of cytochrome c oxidase (Complex IV) physical 2 2 2 Reconstituted Complex, Co-purification
COX3 Q0275 Subunit III of cytochrome c oxidase (Complex IV) physical 2 2 2 Co-purification, Reconstituted Complex
ATP11 YNL315C Molecular chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 2 1 2 Negative Genetic, Negative Genetic
APL4 YPR029C Gamma-adaptin genetic 2 1 2 Negative Genetic, Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA genetic 2 1 2 Negative Genetic, Negative Genetic
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP12 YJL180C Assembly factor for F1 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
SOR2 YDL246C Sorbitol dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
YPT31 YER031C Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
MND1 YGL183C Protein required for recombination and meiotic nuclear division genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Positive Genetic, Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
RGT1 YKL038W Glucose-responsive transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
ELA1 YNL230C Elongin A genetic 2 1 2 Negative Genetic, Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 2 1 2 Negative Genetic, Negative Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 2 1 1 Negative Genetic, Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 2 1 1 Negative Genetic, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Negative Genetic, Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 1 Negative Genetic, Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 2 1 1 Negative Genetic, Negative Genetic
RPL26B YGR034W Ribosomal 60S subunit protein L26B genetic 2 1 1 Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 2 1 1 Negative Genetic, Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 2 1 1 Negative Genetic, Negative Genetic
SNN1 YNL086W Subunit of the BLOC-1 complex involved in endosomal maturation genetic 2 1 1 Negative Genetic, Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Negative Genetic, Negative Genetic
KTR6 YPL053C Probable mannosylphosphate transferase genetic 2 1 1 Negative Genetic, Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family regulation 1 1 1 RNA-sequencing evidence
SIR3 YLR442C Silencing protein regulation 1 1 1 RNA-sequencing evidence
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains regulation 1 1 1 RNA-sequencing evidence
HAP1 YLR256W Zinc finger transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HAP4 YKL109W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 1 1 1 Affinity Capture-MS
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
ABD1 YBR236C Methyltransferase genetic 1 1 1 Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
COX4 YGL187C Subunit IV of cytochrome c oxidase physical 1 1 1 Affinity Capture-MS
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CKI1 YLR133W Choline kinase genetic 1 1 1 Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway genetic 1 1 1 Negative Genetic
ALY2 YJL084C Alpha arrestin, Ub-ligase adaptor for Rsp5p genetic 1 1 1 Negative Genetic
COQ5 YML110C 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
COB Q0105 Cytochrome b physical 1 1 1 Reconstituted Complex
ATP17 YDR377W Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
AIM45 YPR004C Putative ortholog of mammalian ETF-alpha genetic 1 1 1 Negative Genetic
AVT1 YJR001W Vacuolar transporter genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ALD4 YOR374W Mitochondrial aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme physical 1 1 1 PCA
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) physical 1 1 1 PCA
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase physical 1 1 1 PCA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 PCA
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 PCA
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
PSF1 YDR013W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) genetic 1 1 1 Negative Genetic
RLI1 YDR091C Essential Fe-S protein genetic 1 1 1 Negative Genetic
SRP101 YDR292C Signal recognition particle (SRP) receptor alpha subunit genetic 1 1 1 Negative Genetic
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
MIA40 YKL195W Import and assembly protein in mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
SEC39 YLR440C Component of the Dsl1p tethering complex genetic 1 1 1 Negative Genetic
HXT2 YMR011W High-affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 1 1 1 Negative Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
SIP3 YNL257C Putative sterol transfer protein genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Positive Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 1 1 1 Positive Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Positive Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
MUP3 YHL036W Low affinity methionine permease genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
IPT1 YDR072C Inositolphosphotransferase genetic 1 1 1 Negative Genetic
FCY21 YER060W Putative purine-cytosine permease genetic 1 1 1 Positive Genetic
URA4 YLR420W Dihydroorotase genetic 1 1 1 Positive Genetic
SKN1 YGR143W Protein involved in sphingolipid biosynthesis genetic 1 1 1 Positive Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Positive Genetic
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase genetic 1 1 1 Positive Genetic
THI7 YLR237W Plasma membrane transporter responsible for the uptake of thiamine genetic 1 1 1 Negative Genetic
UGA1 YGR019W Gamma-aminobutyrate (GABA) transaminase genetic 1 1 1 Negative Genetic
GND2 YGR256W 6-phosphogluconate dehydrogenase (decarboxylating) genetic 1 1 1 Positive Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Positive Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Positive Genetic
MRPL32 YCR003W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Positive Genetic
MRPS28 YDR337W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
MRF1 YGL143C Mitochondrial translation release factor genetic 1 1 1 Positive Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Positive Genetic
MHP1 YJL042W Microtubule-associated protein involved in microtubule organization genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Positive Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Positive Genetic
MRPL20 YKR085C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Positive Genetic
YMR090W YMR090W Putative protein of unknown function genetic 1 1 1 Positive Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Positive Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein genetic 1 1 1 Positive Genetic
SUV3 YPL029W ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
SRP68 YPL243W Core component of the signal recognition particle (SRP) complex genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
NEO1 YIL048W Phospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
YAR028W YAR028W Putative integral membrane protein genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
GDT1 YBR187W Calcium and manganese transporter with higher affinity for Ca2+ genetic 1 1 1 Negative Genetic
YBR287W YBR287W Protein of unknown function genetic 1 1 1 Negative Genetic
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
LSB5 YCL034W Protein involved in membrane-trafficking events at plasma membrane genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p genetic 1 1 1 Negative Genetic
PHO2 YDL106C Homeobox transcription factor genetic 1 1 1 Negative Genetic
SNF3 YDL194W Plasma membrane low glucose sensor, regulates glucose transport genetic 1 1 1 Negative Genetic
PAA1 YDR071C Polyamine acetyltransferase genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
SND1 YDR186C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
TRP4 YDR354W Anthranilate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
PKH1 YDR490C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Negative Genetic
MNN1 YER001W Alpha-1,3-mannosyltransferase genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
YER134C YER134C Magnesium-dependent acid phosphatase genetic 1 1 1 Negative Genetic
PAU5 YFL020C Member of the seripauperin multigene family genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein genetic 1 1 1 Negative Genetic
YGR035W-A YGR035W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SAE3 YHR079C-A Meiosis-specific protein involved in meiotic recombination genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
SSP1 YHR184W Protein involved in the control of meiotic nuclear division genetic 1 1 1 Negative Genetic
LNP1 YHR192W Lunapark family member involved in ER network formation genetic 1 1 1 Negative Genetic
SNL1 YIL016W Ribosome-associated protein genetic 1 1 1 Negative Genetic
YIL055C YIL055C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Negative Genetic
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
CPS1 YJL172W Vacuolar carboxypeptidase S genetic 1 1 1 Negative Genetic
TMA22 YJR014W Protein of unknown function genetic 1 1 1 Negative Genetic
VPS55 YJR044C Late endosomal protein involved in late endosome to vacuole transport genetic 1 1 1 Negative Genetic
URA8 YJR103W Minor CTP synthase isozyme (see also URA7) genetic 1 1 1 Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
YKR005C YKR005C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YSR3 YKR053C Dihydrosphingosine 1-phosphate phosphatase genetic 1 1 1 Negative Genetic
EMC6 YLL014W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes genetic 1 1 1 Negative Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Negative Genetic
DPA10 YLR307C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Negative Genetic
TRM12 YML005W S-adenosylmethionine-dependent methyltransferase genetic 1 1 1 Negative Genetic
HMG1 YML075C HMG-CoA reductase genetic 1 1 1 Negative Genetic
UBC7 YMR022W Ubiquitin conjugating enzyme genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Negative Genetic
YMR084W YMR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS16A YMR143W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Negative Genetic
MDR1 YGR100W Cytoplasmic GTPase-activating protein genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CRP1 YHR146W Protein that binds to cruciform DNA structures genetic 1 1 1 Negative Genetic
FYV10 YIL097W Subunit of GID complex genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
PTK2 YJR059W Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
DCW1 YKL046C Putative mannosidase genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
NOP13 YNL175C Nucleolar protein found in preribosomal complexes genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
SPS18 YNL204C Protein of unknown function, contains a putative zinc-binding domain genetic 1 1 1 Negative Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
DSC2 YOL073C Multi-transmembrane subunit of the DSC ubiquitin ligase complex genetic 1 1 1 Negative Genetic
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
YOR034C-A YOR034C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SYC1 YOR179C Subunit of the APT subcomplex of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SPR2 YOR214C Putative spore wall protein genetic 1 1 1 Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
PEP4 YPL154C Vacuolar aspartyl protease (proteinase A) genetic 1 1 1 Negative Genetic
SVS1 YPL163C Cell wall and vacuolar protein genetic 1 1 1 Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Positive Genetic
COX16 YJL003W Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
BNA4 YBL098W Kynurenine 3-monooxygenase genetic 1 1 1 Positive Genetic