RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
9 |
4 |
9 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
7 |
3 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
6 |
4 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Reconstituted Complex, Affinity Capture-Western |
RPN2 |
YIL075C |
Subunit of the 26S proteasome |
physical |
5 |
4 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, PCA, Affinity Capture-Western |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
5 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
4 |
3 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
4 |
1 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
3 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Affinity Capture-MS |
NAS6 |
YGR232W |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Reconstituted Complex |
ECM29 |
YHL030W |
Scaffold protein |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MSK1 |
YNL073W |
Mitochondrial lysine-tRNA synthetase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSM3 |
YBR272C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP49 |
YKL167C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO80 |
YGL150C |
Nucleosome spacing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN14 |
YGL004C |
Evolutionarily conserved 19S regulatory particle assembly-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SIZ1 |
YDR409W |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA11 |
YHR159W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA6 |
YPL074W |
Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP42 |
YDL111C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
physical |
1 |
1 |
1 |
Proximity Label-MS |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HFL1 |
YKR051W |
Vacuole membrane protein that interacts with Atg8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GZF3 |
YJL110C |
GATA zinc finger protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRF1 |
YGR246C |
TFIIIB B-related factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRF1 |
YGR246C |
TFIIIB B-related factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
JIP4 |
YDR475C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNT2 |
YGL257C |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |