Standard name Systematic name Name description Description
HHF1 YBR009C Histone H4 Histone H4; core histone protein required for chromatin assembly and chromosome function; one of two identical histone proteins (see also HHF2); contributes to telomeric silencing; involved in mRNA multiplexing; N-terminal domain involved in maintaining genomic integrity
Visualize the interactome of HHF1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.071 0.087 NaN
Mito 0.412 0.399 0.174
Nucleolus 0.435 0.372 0.681
Nucleus 0.871 0.842 0.870

GFP localization & abundance

GFP localization GFP abundance
nucleus 524000

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
HHF1 1 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ASF1 YJL115W Nucleosome assembly factor physical 18 5 17 Affinity Capture-MS, Affinity Capture-MS, Co-purification, Reconstituted Complex, PCA, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
HHT1 YBR010W Histone H3 physical 16 6 15 Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-localization, Co-localization, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, FRET, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
SIR3 YLR442C Silencing protein physical 16 4 13 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Protein-peptide, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Reconstituted Complex
HIF1 YLL022C Non-essential component of the HAT-B histone acetyltransferase complex physical 12 5 11 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western
HAT1 YPL001W Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 10 4 9 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Biochemical Activity, Biochemical Activity
RTT106 YNL206C Histone chaperone physical 10 3 7 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
HHT2 YNL031C Histone H3 physical 9 4 9 Affinity Capture-Western, Affinity Capture-MS, PCA, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
CSE4 YKL049C Centromeric histone H3-like protein physical 9 5 8 Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Co-crystal Structure, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
HTA1 YDR225W Histone H2A physical 8 4 8 Affinity Capture-MS, Reconstituted Complex, Co-purification, Co-purification, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 8 3 8 Biochemical Activity, Biochemical Activity, Co-localization, Biochemical Activity, Biochemical Activity, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
HTZ1 YOL012C Histone variant H2AZ physical 8 3 8 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, FRET, Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 8 3 8 Reconstituted Complex, Biochemical Activity, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity
BDF1 YLR399C BET family transcriptional regulator physical 8 4 7 Two-hybrid, Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western
ASF1 YJL115W Nucleosome assembly factor genetic 8 3 6 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Negative Genetic, Negative Genetic
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p genetic 8 4 5 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Dosage Growth Defect, Negative Genetic, Negative Genetic
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p physical 7 1 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 7 4 6 Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Rescue, Dosage Lethality, Negative Genetic, Synthetic Growth Defect
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex physical 7 3 6 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 7 3 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
HTB1 YDR224C Histone H2B physical 7 2 6 Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 7 3 4 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family physical 6 4 6 Biochemical Activity, Co-localization, Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription physical 6 2 6 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
ORC1 YML065W Largest subunit of the origin recognition complex physical 6 4 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-crystal Structure, Reconstituted Complex
HHT1 YBR010W Histone H3 genetic 5 5 5 Phenotypic Enhancement, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Dosage Lethality
SIR4 YDR227W SIR protein involved in assembly of silent chromatin domains physical 5 3 5 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) physical 5 3 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex
HTA2 YBL003C Histone H2A physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 5 2 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
HTA1 YDR225W Histone H2A genetic 5 4 4 Dosage Growth Defect, Positive Genetic, Positive Genetic, Synthetic Lethality, Synthetic Growth Defect
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 5 3 4 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
RAD52 YML032C Protein involved in homologous recombination genetic 5 3 4 Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
CTF3 YLR381W Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p genetic 5 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 5 2 4 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HHF2 YNL030W Histone H4 genetic 5 2 4 Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic, Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 5 2 4 Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex physical 5 4 3 Affinity Capture-Western, Far Western, Reconstituted Complex, Reconstituted Complex, Protein-peptide
KAP123 YER110C Karyopherin beta physical 5 3 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA physical 5 3 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I physical 5 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 5 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MCM22 YJR135C Outer kinetochore protein and component of the Ctf3 subcomplex genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
FKH2 YNL068C Forkhead family transcription factor regulation 4 3 4 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation genetic 4 3 4 Dosage Rescue, Phenotypic Suppression, Synthetic Lethality, Phenotypic Suppression
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Biochemical Activity, Biochemical Activity
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase physical 4 4 3 Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Biochemical Activity
HTB1 YDR224C Histone H2B genetic 4 3 3 Dosage Growth Defect, Positive Genetic, Positive Genetic, Synthetic Growth Defect
RTT106 YNL206C Histone chaperone genetic 4 3 3 Negative Genetic, Synthetic Rescue, Dosage Growth Defect, Negative Genetic
RSC3 YDR303C Component of the RSC chromatin remodeling complex physical 4 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 4 2 3 Biochemical Activity, Affinity Capture-Western, Biochemical Activity, Biochemical Activity
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation physical 4 2 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex
RRN10 YBL025W Protein involved in promoting high level transcription of rDNA physical 4 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 4 2 3 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIF1 YBR275C Protein involved in control of DNA replication genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MAD3 YJL013C Subunit of spindle-assembly checkpoint complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRC15 YPL017C Microtubule associated protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCM3 YDL139C Nonhistone component of centromeric chromatin genetic 3 3 3 Dosage Rescue, Phenotypic Suppression, Negative Genetic
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 3 3 3 Phenotypic Suppression, Positive Genetic, Negative Genetic
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 3 3 3 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Suppression
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling physical 3 3 3 Affinity Capture-Western, Affinity Capture-Luminescence, Protein-peptide
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 3 3 3 Reconstituted Complex, PCA, Affinity Capture-MS
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 3 2 3 Affinity Capture-MS, Biochemical Activity, Biochemical Activity
INO80 YGL150C Nucleosome spacing factor physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 3 2 3 Dosage Lethality, Dosage Rescue, Dosage Rescue
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 3 2 3 Dosage Lethality, Synthetic Growth Defect, Synthetic Growth Defect
RTT102 YGR275W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 3 2 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
HHF2 YNL030W Histone H4 physical 3 2 3 Affinity Capture-MS, PCA, Affinity Capture-MS
MOT1 YPL082C Essential protein involved in regulation of transcription physical 3 2 3 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS
RSC2 YLR357W Component of the RSC chromatin remodeling complex physical 3 2 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 3 2 3 Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex physical 3 2 3 Co-localization, Co-localization, Affinity Capture-MS
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling physical 3 2 3 Co-localization, Co-localization, Affinity Capture-MS
SCM3 YDL139C Nonhistone component of centromeric chromatin physical 3 2 3 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex physical 3 2 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 3 2 3 Negative Genetic, Phenotypic Suppression, Negative Genetic
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Synthetic Lethality
CAC2 YML102W Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p physical 3 2 3 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
CLA4 YNL298W Cdc42p-activated signal transducing kinase physical 3 2 3 Affinity Capture-MS, Biochemical Activity, Biochemical Activity
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KRE33 YNL132W Acetyltransferase required for biogenesis of small ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
IRC20 YLR247C E3 ubiquitin ligase and putative helicase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HPC2 YBR215W Subunit of the HIR complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
PDP3 YLR455W Component of the NuA3b histone acetyltransferase complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 physical 3 1 3 Biochemical Activity, Biochemical Activity, Biochemical Activity
UBP6 YFR010W Ubiquitin-specific protease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAC3 YDR159W mRNA export factor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ABF2 YMR072W Mitochondrial DNA-binding protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling physical 3 3 2 Far Western, Two-hybrid, Affinity Capture-Luminescence
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
GIS1 YDR096W Histone demethylase and transcription factor genetic 3 3 2 Negative Genetic, Phenotypic Suppression, Phenotypic Enhancement
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex physical 3 2 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MCM2 YBL023C Protein involved in DNA replication physical 3 2 2 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 3 2 2 Synthetic Rescue, Dosage Lethality, Synthetic Rescue
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CBF2 YGR140W Essential kinetochore protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ESC1 YMR219W Protein involved in telomeric silencing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HAL9 YOL089C Putative transcription factor containing a zinc finger genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
BDF1 YLR399C BET family transcriptional regulator genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 2 2 2 Affinity Capture-Western, Biochemical Activity
SIR3 YLR442C Silencing protein genetic 2 2 2 Dosage Lethality, Synthetic Rescue
HIR1 YBL008W Subunit of the HIR complex physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
HHT2 YNL031C Histone H3 genetic 2 2 2 Phenotypic Suppression, Dosage Lethality
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 2 2 2 Dosage Lethality, Synthetic Growth Defect
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex physical 2 2 2 Affinity Capture-MS, Protein-peptide
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 2 2 2 Synthetic Rescue, Dosage Lethality
SRM1 YGL097W Nucleotide exchange factor for Gsp1p physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex physical 2 2 2 Co-localization, Affinity Capture-MS
VPS75 YNL246W NAP family histone chaperone physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RSC1 YGR056W Component of the RSC chromatin remodeling complex physical 2 2 2 Affinity Capture-Western, Reconstituted Complex
RTT109 YLL002W Histone acetyltransferase physical 2 2 2 Reconstituted Complex, Biochemical Activity
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
NPL6 YMR091C Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC30 YHR056C Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC4 YKR008W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC58 YLR033W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC6 YCR052W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RSC9 YML127W Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SFH1 YLR321C Component of the RSC chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SNF12 YNR023W 73 kDa subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 2 2 Synthetic Rescue, Positive Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 2 2 Positive Genetic, Synthetic Rescue
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 2 2 2 Synthetic Rescue, Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
RAD52 YML032C Protein involved in homologous recombination physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 2 2 2 Protein-peptide, Reconstituted Complex
HPR1 YDR138W Subunit of THO/TREX complexes genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 2 Negative Genetic, Phenotypic Suppression
SUB1 YMR039C Transcriptional regulator genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SIR1 YKR101W Protein involved in silencing at mating-type loci HML and HMR genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 2 2 2 Affinity Capture-MS, Affinity Capture-RNA
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 2 1 2 Negative Genetic, Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 2 1 2 Positive Genetic, Positive Genetic
BDF2 YDL070W Protein involved in transcription initiation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ECM5 YMR176W Subunit of the Snt2C complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NMD5 YJR132W Karyopherin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRO1 YDR300C Gamma-glutamyl kinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PSD2 YGR170W Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPC40 YPR110C RNA polymerase subunit AC40 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YFR006W YFR006W Putative X-Pro aminopeptidase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
REA1 YLR106C Huge dynein-related AAA-type ATPase (midasin) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PSH1 YOL054W E3 ubiquitin ligase targeting centromere-binding protein Cse4p genetic 2 1 2 Negative Genetic, Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
RAD53 YPL153C DNA damage response kinase physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
HTB2 YBL002W Histone H2B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MAM33 YIL070C Acidic protein of the mitochondrial matrix physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IOC3 YFR013W Subunit of the Isw1a complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MAE1 YKL029C Mitochondrial malic enzyme physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Synthetic Rescue, Synthetic Rescue
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 2 1 2 Reconstituted Complex, Reconstituted Complex
MED1 YPR070W Subunit of the RNA polymerase II mediator complex physical 2 1 2 Reconstituted Complex, Reconstituted Complex
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex physical 2 1 2 Reconstituted Complex, Reconstituted Complex
RPC82 YPR190C RNA polymerase III subunit C82 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 2 1 2 Positive Genetic, Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 2 1 2 Negative Genetic, Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 2 1 2 Negative Genetic, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 1 2 Negative Genetic, Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
PDS1 YDR113C Securin genetic 2 1 2 Negative Genetic, Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 2 Negative Genetic, Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 2 1 2 Positive Genetic, Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BRF1 YGR246C TFIIIB B-related factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 2 1 2 Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 2 Negative Genetic, Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 2 1 2 Negative Genetic, Negative Genetic
NHP6B YBR089C-A High-mobility group (HMG) protein physical 2 2 1 PCA, Reconstituted Complex
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 2 2 1 Synthetic Rescue, Phenotypic Suppression
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex physical 2 1 1 Reconstituted Complex, Reconstituted Complex
MIF2 YKL089W Centromeric CDEIII region binding protein physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 2 1 1 Dosage Lethality, Dosage Lethality
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 1 1 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
THI2 YBR240C Transcriptional activator of thiamine biosynthetic genes regulation 1 1 1 DNA to cDNA expression microarray evidence
NHP6A YPR052C High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CLA4 YNL298W Cdc42p-activated signal transducing kinase regulation 1 1 1 protein kinase assay evidence
STE11 YLR362W Signal transducing MEK kinase regulation 1 1 1 protein kinase assay evidence
STE20 YHL007C Cdc42p-activated signal transducing kinase regulation 1 1 1 protein kinase assay evidence
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 regulation 1 1 1 in vitro methylation assay evidence
NHP6B YBR089C-A High-mobility group (HMG) protein regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
CDC73 YLR418C Component of the Paf1p complex physical 1 1 1 Affinity Capture-MS
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs physical 1 1 1 Affinity Capture-MS
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
ENP2 YGR145W Component of the SSU physical 1 1 1 Affinity Capture-MS
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 1 1 1 Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family genetic 1 1 1 Negative Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex physical 1 1 1 Reconstituted Complex
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-Luminescence
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Affinity Capture-MS
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing physical 1 1 1 Affinity Capture-MS
ACC1 YNR016C Acetyl-CoA carboxylase, biotin containing enzyme physical 1 1 1 Affinity Capture-MS
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex physical 1 1 1 Affinity Capture-MS
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex physical 1 1 1 Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein physical 1 1 1 Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) physical 1 1 1 Affinity Capture-MS
BUD20 YLR074C C2H2-type zinc finger protein required for ribosome assembly physical 1 1 1 Affinity Capture-MS
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex physical 1 1 1 Reconstituted Complex
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor physical 1 1 1 Affinity Capture-Western
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Phenotypic Enhancement
CYR1 YJL005W Adenylate cyclase physical 1 1 1 Affinity Capture-MS
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Positive Genetic
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex physical 1 1 1 Affinity Capture-Western
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 1 1 1 Affinity Capture-MS
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Affinity Capture-MS
GLY1 YEL046C Threonine aldolase physical 1 1 1 Affinity Capture-MS
ICL1 YER065C Isocitrate lyase physical 1 1 1 Affinity Capture-MS
MAC1 YMR021C Copper-sensing transcription factor physical 1 1 1 Affinity Capture-MS
MSB1 YOR188W Protein of unknown function physical 1 1 1 Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 1 1 1 Affinity Capture-MS
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) physical 1 1 1 Affinity Capture-MS
VTH2 YJL222W Putative membrane glycoprotein physical 1 1 1 Affinity Capture-MS
UTP20 YBL004W Component of the small-subunit (SSU) processome physical 1 1 1 Affinity Capture-MS
LIP2 YLR239C Lipoyl ligase physical 1 1 1 Affinity Capture-MS
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
SMC6 YLR383W Subunit of the SMC5-SMC6 complex physical 1 1 1 Affinity Capture-MS
PTP3 YER075C Phosphotyrosine-specific protein phosphatase physical 1 1 1 Affinity Capture-MS
SEN15 YMR059W Subunit of the tRNA splicing endonuclease physical 1 1 1 Affinity Capture-MS
RAD16 YBR114W Nucleotide excision repair (NER) protein physical 1 1 1 Affinity Capture-MS
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression physical 1 1 1 Affinity Capture-MS
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis physical 1 1 1 Affinity Capture-MS
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
IPI3 YNL182C Component of the Rix1 complex and pre-replicative complexes (pre-RCs) physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways physical 1 1 1 Affinity Capture-MS
STH1 YIL126W ATPase component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Rescue
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 1 1 1 Reconstituted Complex
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Rescue
HIR2 YOR038C Subunit of HIR nucleosome assembly complex physical 1 1 1 Affinity Capture-Western
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Dosage Rescue
NAT4 YMR069W N alpha-acetyl-transferase physical 1 1 1 Biochemical Activity
NAT4 YMR069W N alpha-acetyl-transferase genetic 1 1 1 Phenotypic Suppression
SPC110 YDR356W Inner plaque spindle pole body (SPB) component physical 1 1 1 Co-purification
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Synthetic Growth Defect
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
YCR043C YCR043C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex physical 1 1 1 Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer physical 1 1 1 Affinity Capture-MS
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
MCM1 YMR043W Transcription factor physical 1 1 1 Affinity Capture-MS
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex physical 1 1 1 Affinity Capture-MS
MCM16 YPR046W Component of the Ctf19 complex and the COMA subcomplex genetic 1 1 1 Negative Genetic
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 1 1 1 Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 1 1 1 Affinity Capture-MS
REB1 YBR049C RNA polymerase I enhancer binding protein physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Growth Defect
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
RPL38 YLR325C Ribosomal 60S subunit protein L38 physical 1 1 1 Affinity Capture-MS
YNK1 YKL067W Nucleoside diphosphate kinase physical 1 1 1 Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 1 1 1 Affinity Capture-MS
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TIF4632 YGL049C Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-MS
RPL7B YPL198W Ribosomal 60S subunit protein L7B physical 1 1 1 Affinity Capture-MS
NOP13 YNL175C Nucleolar protein found in preribosomal complexes physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 1 1 1 Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RPL13B YMR142C Ribosomal 60S subunit protein L13B physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
TOF2 YKR010C Protein required for rDNA silencing and mitotic rDNA condensation physical 1 1 1 Affinity Capture-MS
NUC1 YJL208C Major mitochondrial nuclease physical 1 1 1 Affinity Capture-MS
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-Western
HST3 YOR025W Sirtuin, histone H3 deacetylase physical 1 1 1 Biochemical Activity
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Synthetic Rescue
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
NHP6A YPR052C High-mobility group (HMG) protein physical 1 1 1 PCA
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Dosage Lethality
RPN10 YHR200W Proteasome polyubiquitin receptor physical 1 1 1 Affinity Capture-MS
LGE1 YPL055C Protein involved in histone H2B ubiquitination physical 1 1 1 Affinity Capture-MS
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Synthetic Growth Defect
IGO1 YNL157W Protein required for initiation of G0 program physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Biochemical Activity
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class genetic 1 1 1 Negative Genetic
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 1 1 1 Biochemical Activity
MED8 YBR193C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
HTL1 YCR020W-B Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
LDB7 YBL006C Component of the RSC chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex physical 1 1 1 Reconstituted Complex
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance physical 1 1 1 Affinity Capture-MS
RPC11 YDR045C RNA polymerase III subunit C11 physical 1 1 1 Affinity Capture-MS
RPC31 YNL151C RNA polymerase III subunit C31 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
RPO26 YPR187W RNA polymerase subunit ABC23 physical 1 1 1 Affinity Capture-MS
RPO31 YOR116C RNA polymerase III largest subunit C160 physical 1 1 1 Affinity Capture-MS
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
RPC34 YNR003C RNA polymerase III subunit C34 physical 1 1 1 Affinity Capture-MS
TIF35 YDR429C eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PRP39 YML046W U1 snRNP protein involved in splicing physical 1 1 1 Affinity Capture-MS
RPC53 YDL150W RNA polymerase III subunit C53 physical 1 1 1 Affinity Capture-MS
RPC25 YKL144C RNA polymerase III subunit C25 physical 1 1 1 Affinity Capture-MS
RPC37 YKR025W RNA polymerase III subunit C37 physical 1 1 1 Affinity Capture-MS
RPC17 YJL011C RNA polymerase III subunit C17 physical 1 1 1 Affinity Capture-MS
MTC1 YJL123C Protein of unknown function that may interact with ribosomes physical 1 1 1 Affinity Capture-MS
RIF1 YBR275C Protein involved in control of DNA replication physical 1 1 1 Affinity Capture-MS
MRPL13 YKR006C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
TUM1 YOR251C Rhodanese domain sulfur transferase physical 1 1 1 Affinity Capture-MS
PSP2 YML017W Asn rich cytoplasmic protein that contains RGG motifs physical 1 1 1 Affinity Capture-MS
HPC2 YBR215W Subunit of the HIR complex physical 1 1 1 Affinity Capture-MS
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p physical 1 1 1 Affinity Capture-MS
VID27 YNL212W Cytoplasmic protein of unknown function physical 1 1 1 Affinity Capture-MS
NMA111 YNL123W Serine protease and general molecular chaperone physical 1 1 1 Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response physical 1 1 1 Affinity Capture-MS
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 1 1 1 Affinity Capture-MS
PDR11 YIL013C ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta physical 1 1 1 Affinity Capture-MS
RPB8 YOR224C RNA polymerase subunit ABC14.5 physical 1 1 1 Affinity Capture-MS
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-MS
TRI1 YMR233W Non-essential sumoylated protein of unknown function physical 1 1 1 Affinity Capture-MS
RPC10 YHR143W-A RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III physical 1 1 1 Affinity Capture-MS
MIP1 YOR330C Mitochondrial DNA polymerase gamma physical 1 1 1 Affinity Capture-MS
YMR114C YMR114C Protein of unknown function physical 1 1 1 Affinity Capture-MS
TOP1 YOL006C Topoisomerase I physical 1 1 1 Affinity Capture-MS
HMI1 YOL095C Mitochondrial inner membrane localized ATP-dependent DNA helicase physical 1 1 1 Affinity Capture-MS
SPC29 YPL124W Inner plaque spindle pole body (SPB) component physical 1 1 1 Affinity Capture-MS
MRPL10 YNL284C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
TOP2 YNL088W Topoisomerase II physical 1 1 1 Affinity Capture-MS
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
TFC8 YPL007C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism physical 1 1 1 Affinity Capture-MS
MDS3 YGL197W Putative component of the TOR regulatory pathway physical 1 1 1 Affinity Capture-MS
TAO3 YIL129C Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target physical 1 1 1 Affinity Capture-MS
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Phenotypic Suppression
YMR050C YMR050C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YOR142W-B YOR142W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation physical 1 1 1 Affinity Capture-MS
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
TOA2 YKL058W TFIIA small subunit physical 1 1 1 Affinity Capture-MS
IOC2 YLR095C Subunit of the Isw1b complex physical 1 1 1 Affinity Capture-MS
MRPL7 YDR237W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
TDP1 YBR223C Tyrosyl-DNA phosphodiesterase I physical 1 1 1 Affinity Capture-MS
SIP5 YMR140W Protein of unknown function physical 1 1 1 Affinity Capture-MS
IOC4 YMR044W Member of a complex (Isw1b) with Isw1p and Ioc2p physical 1 1 1 Affinity Capture-MS
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Affinity Capture-MS
RTG2 YGL252C Sensor of mitochondrial dysfunction physical 1 1 1 Affinity Capture-MS
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes physical 1 1 1 Affinity Capture-MS
SVF1 YDR346C Protein with a potential role in cell survival pathways physical 1 1 1 Affinity Capture-MS
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRX6 YNL295W Mitochondrial ribosome-associated protein physical 1 1 1 Affinity Capture-MS
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly physical 1 1 1 Affinity Capture-MS
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 1 1 1 Affinity Capture-MS
HIS3 YOR202W Imidazoleglycerol-phosphate dehydratase physical 1 1 1 Affinity Capture-MS
JIP5 YPR169W Protein required for biogenesis of the large ribosomal subunit physical 1 1 1 Affinity Capture-MS
PAL1 YDR348C Protein of unknown function thought to be involved in endocytosis physical 1 1 1 Affinity Capture-MS
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 physical 1 1 1 Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 1 1 1 Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Negative Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 1 1 1 Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles physical 1 1 1 Affinity Capture-MS
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Negative Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
PAP2 YOL115W Non-canonical poly(A) polymerase physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
RPA49 YNL248C RNA polymerase I subunit A49 physical 1 1 1 Affinity Capture-MS
RQC2 YPL009C Component of the Ribosome Quality Control (RQC) complex physical 1 1 1 Affinity Capture-MS
SNX41 YDR425W Sorting nexin physical 1 1 1 Affinity Capture-MS
YLR278C YLR278C Zinc-cluster protein physical 1 1 1 Affinity Capture-MS
SSF1 YHR066W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways physical 1 1 1 Affinity Capture-MS
MOT3 YMR070W Transcriptional repressor, activator physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-MS
NSI1 YDR026C RNA polymerase I termination factor physical 1 1 1 Affinity Capture-MS
IRC5 YFR038W Putative ATPase containing the DEAD/H helicase-related sequence motif physical 1 1 1 Affinity Capture-MS
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis physical 1 1 1 Affinity Capture-MS
ORC3 YLL004W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
YAP1801 YHR161C Protein of the AP180 family, involved in clathrin cage assembly physical 1 1 1 Affinity Capture-MS
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor physical 1 1 1 Affinity Capture-MS
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 1 1 1 Affinity Capture-MS
YGL039W YGL039W Aldehyde reductase physical 1 1 1 Affinity Capture-MS
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes physical 1 1 1 Affinity Capture-MS
RGC1 YPR115W Putative regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-MS
RCL1 YOL010W Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
NET1 YJL076W Core subunit of the RENT complex physical 1 1 1 Affinity Capture-MS
SRP40 YKR092C Nucleolar serine-rich protein physical 1 1 1 Affinity Capture-MS
YGR130C YGR130C Component of the eisosome with unknown function physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
UME6 YDR207C Rpd3L histone deacetylase complex subunit physical 1 1 1 Affinity Capture-MS
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex physical 1 1 1 Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 1 1 1 Affinity Capture-MS
YPL150W YPL150W Protein kinase of unknown cellular role physical 1 1 1 Affinity Capture-MS
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth physical 1 1 1 Affinity Capture-MS
ORC4 YPR162C Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
KIN1 YDR122W S/T protein kinase physical 1 1 1 Affinity Capture-MS
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis physical 1 1 1 Affinity Capture-MS
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates physical 1 1 1 Affinity Capture-MS
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family physical 1 1 1 Affinity Capture-MS
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 Affinity Capture-MS
YPK2 YMR104C AGC-type S/T protein kinase physical 1 1 1 Affinity Capture-MS
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
SGM1 YJR134C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SDA1 YGR245C Protein required for actin organization and passage through Start physical 1 1 1 Affinity Capture-MS
UPC2 YDR213W Sterol regulatory element binding protein physical 1 1 1 Affinity Capture-MS
SOK1 YDR006C Protein of unknown function physical 1 1 1 Affinity Capture-MS
STB4 YMR019W Putative transcription factor physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-MS
RGT1 YKL038W Glucose-responsive transcription factor physical 1 1 1 Affinity Capture-MS
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Affinity Capture-MS
UTP22 YGR090W Component of the small-subunit processome physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
SEC3 YER008C Subunit of the exocyst complex physical 1 1 1 Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex physical 1 1 1 Affinity Capture-MS
ORC5 YNL261W Subunit of the origin recognition complex (ORC) physical 1 1 1 Affinity Capture-MS
ICS2 YBR157C Protein of unknown function physical 1 1 1 Affinity Capture-MS
MRPL36 YBR122C Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Affinity Capture-MS
TAE1 YBR261C AdoMet-dependent proline methyltransferase physical 1 1 1 Affinity Capture-MS
HOS3 YPL116W Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) physical 1 1 1 Affinity Capture-MS
RPA43 YOR340C RNA polymerase I subunit A43 physical 1 1 1 Affinity Capture-MS
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci physical 1 1 1 Affinity Capture-MS
REF2 YDR195W RNA-binding protein physical 1 1 1 Affinity Capture-MS
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth physical 1 1 1 Affinity Capture-MS
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 1 1 1 Affinity Capture-MS
PCA1 YBR295W Cadmium transporting P-type ATPase physical 1 1 1 Affinity Capture-MS
YJL113W YJL113W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
SET5 YHR207C Methyltransferase involved in methylation of histone H4 Lys5, -8, -12 genetic 1 1 1 Positive Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 1 1 1 Affinity Capture-MS
RLP7 YNL002C Nucleolar protein similar to large ribosomal subunit L7 proteins physical 1 1 1 Affinity Capture-MS
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex physical 1 1 1 Reconstituted Complex
IES4 YOR189W Component of the INO80 chromatiin remodeling complex physical 1 1 1 Reconstituted Complex
IES6 YEL044W Component of the INO80 chromatin remodeling complex physical 1 1 1 Reconstituted Complex
OTU1 YFL044C Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p physical 1 1 1 Affinity Capture-MS
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
SPT21 YMR179W Protein with a role in transcriptional silencing physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Synthetic Rescue
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
HSP104 YLL026W Disaggregase physical 1 1 1 Affinity Capture-MS
THP1 YOL072W Nuclear pore-associated protein physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein physical 1 1 1 Protein-peptide
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Phenotypic Suppression
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Affinity Capture-MS
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
VID30 YGL227W Central component of GID Complex, involved in FBPase degradation physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease physical 1 1 1 Reconstituted Complex
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
SPN1 YPR133C Protein involved in RNA polymerase II transcription physical 1 1 1 Reconstituted Complex
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
SWR1 YDR334W Swi2/Snf2-related ATPase physical 1 1 1 Reconstituted Complex
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family physical 1 1 1 Affinity Capture-MS
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SLD5 YDR489W Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) physical 1 1 1 Affinity Capture-MS
KIN3 YAR018C Nonessential serine/threonine protein kinase physical 1 1 1 Biochemical Activity
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases physical 1 1 1 Biochemical Activity
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif physical 1 1 1 Biochemical Activity
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform physical 1 1 1 Biochemical Activity
STE7 YDL159W Signal transducing MAP kinase kinase physical 1 1 1 Biochemical Activity
RTK1 YDL025C Putative protein kinase, potentially phosphorylated by Cdc28p physical 1 1 1 Biochemical Activity
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
MPS1 YDL028C Dual-specificity kinase physical 1 1 1 Biochemical Activity
STE11 YLR362W Signal transducing MEK kinase physical 1 1 1 Biochemical Activity
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Synthetic Lethality
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase genetic 1 1 1 Synthetic Rescue
LYS2 YBR115C Alpha aminoadipate reductase genetic 1 1 1 Synthetic Rescue
TAF13 YML098W TFIID subunit (19 kDa) genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Phenotypic Suppression
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
MET18 YIL128W Component of cytosolic iron-sulfur protein assembly (CIA) machinery genetic 1 1 1 Negative Genetic
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Positive Genetic
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Positive Genetic
VID22 YLR373C G-quadruplex (G4) DNA binding protein genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Positive Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Positive Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Positive Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Positive Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Synthetic Growth Defect
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Growth Defect
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 1 1 1 Synthetic Growth Defect
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 1 1 1 Phenotypic Suppression
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
PDR8 YLR266C Transcription factor genetic 1 1 1 Negative Genetic
MIG1 YGL035C Transcription factor involved in glucose repression genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Positive Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Negative Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Positive Genetic
STB6 YKL072W Protein that binds Sin3p in a two-hybrid assay genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Positive Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
RPA14 YDR156W RNA polymerase I subunit A14 genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Positive Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 1 1 1 Positive Genetic
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Synthetic Growth Defect
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
RAD24 YER173W Checkpoint protein genetic 1 1 1 Synthetic Growth Defect
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Positive Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Positive Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
YVC1 YOR087W Vacuolar cation channel genetic 1 1 1 Positive Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
UTP8 YGR128C Nucleolar protein required for export of tRNAs from the nucleus genetic 1 1 1 Negative Genetic
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
PZF1 YPR186C Transcription factor IIIA (TFIIIA) genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
YAL064W YAL064W Protein of unknown function genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Negative Genetic
RPS23B YPR132W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
MET8 YBR213W Bifunctional dehydrogenase and ferrochelatase genetic 1 1 1 Negative Genetic
OCA4 YCR095C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
MIN10 YFR032C-B Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
RPL9A YGL147C Ribosomal 60S subunit protein L9A genetic 1 1 1 Negative Genetic
YGL188C-A YGL188C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 1 1 1 Negative Genetic
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 1 1 1 Negative Genetic
SET4 YJL105W Chromatin-associated protein involved in control of stress response genetic 1 1 1 Negative Genetic
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 1 1 1 Negative Genetic
YJR011C YJR011C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MLO127 YJR039W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
MRP8 YKL142W Protein of unknown function genetic 1 1 1 Negative Genetic
SSA2 YLL024C HSP70 family ATP-binding protein genetic 1 1 1 Negative Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
PRM6 YML047C Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Negative Genetic
MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
YNR021W YNR021W Putative protein of unknown function genetic 1 1 1 Negative Genetic
YSP3 YOR003W Putative precursor of the subtilisin-like protease III genetic 1 1 1 Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 1 1 1 Negative Genetic
WTM1 YOR230W Transcriptional modulator genetic 1 1 1 Negative Genetic
MRPL40 YPL173W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 1 1 1 Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Synthetic Rescue
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Synthetic Rescue
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Positive Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 1 1 1 Negative Genetic
RIM4 YHL024W Putative RNA-binding protein genetic 1 1 1 Positive Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Positive Genetic
YIP5 YGL161C Protein that interacts with Rab GTPases genetic 1 1 1 Negative Genetic
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Phenotypic Suppression
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
RAD7 YJR052W Nucleotide excision repair (NER) protein genetic 1 1 1 Synthetic Rescue
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Synthetic Rescue
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Phenotypic Suppression
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Suppression
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex physical 1 1 1 Reconstituted Complex
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
FAB1 YFR019W 1-phosphatidylinositol-3-phosphate 5-kinase physical 1 1 1 Affinity Capture-MS
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase physical 1 1 1 Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
APM1 YPL259C Mu1-like medium subunit of the AP-1 complex genetic 1 1 1 Negative Genetic
DIG1 YPL049C MAP kinase-responsive inhibitor of the Ste12p transcription factor physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity genetic 1 1 1 Phenotypic Enhancement
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
HEM13 YDR044W Coproporphyrinogen III oxidase physical 1 1 1 Affinity Capture-MS
FUN30 YAL019W Snf2p family member with ATP-dependent chromatin remodeling activity physical 1 1 1 Reconstituted Complex
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
DIM1 YPL266W Essential 18S rRNA dimethylase (dimethyladenosine transferase) genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Biochemical Activity
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase physical 1 1 1 Affinity Capture-MS
CDC53 YDL132W Cullin physical 1 1 1 Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor physical 1 1 1 Affinity Capture-MS
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) physical 1 1 1 Affinity Capture-MS
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
ATG42 YBR139W Vacuolar serine-type carboxypeptidase physical 1 1 1 Affinity Capture-MS
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CIN8 YEL061C Bipolar kinesin motor protein physical 1 1 1 Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network physical 1 1 1 Biochemical Activity
AI1 Q0050 Reverse transcriptase required for splicing of the COX1 pre-mRNA physical 1 1 1 Affinity Capture-MS
FAL1 YDR021W Nucleolar protein required for maturation of 18S rRNA genetic 1 1 1 Negative Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E physical 1 1 1 Affinity Capture-MS
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase physical 1 1 1 Affinity Capture-MS
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Biochemical Activity
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Biochemical Activity
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Synthetic Rescue
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
FOB1 YDR110W Nucleolar protein that binds the rDNA replication fork barrier site physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
CDC31 YOR257W Calcium-binding component of the spindle pole body (SPB) half-bridge physical 1 1 1 Affinity Capture-MS
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) physical 1 1 1 Affinity Capture-MS
APN1 YKL114C Major apurinic/apyrimidinic endonuclease physical 1 1 1 Affinity Capture-MS
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex physical 1 1 1 Affinity Capture-MS
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase physical 1 1 1 Biochemical Activity
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity physical 1 1 1 Affinity Capture-MS
BNR1 YIL159W Formin physical 1 1 1 Affinity Capture-MS
ARG80 YMR042W Transcription factor involved in regulating arginine-responsive genes genetic 1 1 1 Positive Genetic
DOT1 YDR440W Nucleosomal histone H3-Lys79 methylase genetic 1 1 1 Synthetic Rescue
AZF1 YOR113W Zinc-finger transcription factor physical 1 1 1 Affinity Capture-MS
ETT1 YOR051C Nuclear protein that inhibits replication of Brome mosaic virus physical 1 1 1 Affinity Capture-MS
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Phenotypic Suppression
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly physical 1 1 1 Affinity Capture-MS
CBP1 YJL209W Mitochondrial protein, regulator of COB mRNA stability and translation genetic 1 1 1 Negative Genetic
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
ASG1 YIL130W Zinc cluster protein proposed to be a transcriptional regulator physical 1 1 1 Affinity Capture-MS
ECM21 YBL101C Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p physical 1 1 1 Affinity Capture-MS
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein physical 1 1 1 Affinity Capture-MS
GLK1 YCL040W Glucokinase physical 1 1 1 Affinity Capture-MS
ANY1 YMR010W Protein involved in phospholipid flippase function genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
CCW22 YDR134C Cell wall protein genetic 1 1 1 Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Phenotypic Suppression
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Positive Genetic
ATG41 YPL250C Protein of unknown function genetic 1 1 1 Negative Genetic
FKS3 YMR306W Protein involved in spore wall assembly physical 1 1 1 Affinity Capture-MS
ALK1 YGL021W Atypical protein kinase physical 1 1 1 Affinity Capture-MS
DSD1 YGL196W D-serine dehydratase (aka D-serine ammonia-lyase) genetic 1 1 1 Negative Genetic
CIS1 YLR346C Protein of unknown function found in mitochondria genetic 1 1 1 Negative Genetic
EXO5 YBR163W Mitochondrial 5'-3' exonuclease and sliding exonuclease physical 1 1 1 Affinity Capture-MS