Standard name Systematic name Name description Description
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family Basic leucine zipper transcription factor of the ATF/CREB family; forms a complex with Tup1p and Cyc8p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses
Visualize the interactome of SKO1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.168 NaN NaN
Nucleus 0.877 0.921 0.918
SpindlePole NaN NaN 0.060

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 504

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SKO1 15 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 7 5 5 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, PCA, Co-localization, Co-localization
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 5 1 5 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation- exonuclease evidence, ChEC-Seq experiments
CWP1 YKL096W Cell wall mannoprotein that localizes to birth scars of daughter cells regulation 2 2 2 chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
CYC8 YBR112C General transcriptional co-repressor physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
TUP1 YCR084C General repressor of transcription in complex with Cyc8p physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
SPS18 YNL204C Protein of unknown function, contains a putative zinc-binding domain genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SCH9 YHR205W AGC family protein kinase physical 2 2 1 Affinity Capture-Western, Biochemical Activity
BNI1 YNL271C Formin genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit regulation 1 1 1 quantitative mass spectrometry evidence
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation regulation 1 1 1 electrophoretic mobility shift assay evidence
GRE2 YOL151W 3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
AKR2 YOR034C Ankyrin repeat-containing protein regulation 1 1 1 DNA to cDNA expression microarray evidence
PCL1 YNL289W Cyclin, interacts with cyclin-dependent kinase Pho85p regulation 1 1 1 DNA to cDNA expression microarray evidence
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
DAK1 YML070W Dihydroxyacetone kinase regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
DDR48 YMR173W DNA damage-responsive protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOL150C YOL150C Dubious open reading frame regulation 1 1 1 DNA to cDNA expression microarray evidence
FRE4 YNR060W Ferric reductase regulation 1 1 1 DNA to cDNA expression microarray evidence
HPF1 YOL155C Haze-protective mannoprotein regulation 1 1 1 DNA to cDNA expression microarray evidence
HXT5 YHR096C Hexose transporter with moderate affinity for glucose regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GRE1 YPL223C Hydrophilin essential in desiccation-rehydration process regulation 1 1 1 northern blot evidence
PTR2 YKR093W Integral membrane peptide transporter regulation 1 1 1 DNA to cDNA expression microarray evidence
FAA1 YOR317W Long chain fatty acyl-CoA synthetase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPO20 YMR017W Meiosis-specific subunit of the t-SNARE complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YBL029W YBL029W Non-essential protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SOK2 YMR016C Nuclear protein that negatively regulates pseudohyphal differentiation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PMA1 YGL008C Plasma membrane P2-type H+-ATPase regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
YBL029C-A YBL029C-A Protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YLR297W YLR297W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YLR162W YLR162W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
YML131W YML131W Protein of unknown function regulation 1 1 1 DNA to cDNA expression microarray evidence
RTC3 YHR087W Protein of unknown function involved in RNA metabolism regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
SPS100 YHR139C Protein required for spore wall maturation regulation 1 1 1 northern blot evidence
ENA1 YDR040C P-type ATPase sodium pump regulation 1 1 1 beta-galactosidase reporter gene assay evidence
NOG2 YNR053C Putative GTPase regulation 1 1 1 DNA to cDNA expression microarray evidence
YHR033W YHR033W Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YOR316C-A YOR316C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YKL096C-B YKL096C-B Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGL007C-A YGL007C-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YGL006W-A YGL006W-A Putative protein of unknown function regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CMR3 YPR013C Putative zinc finger protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
THI4 YGR144W Thiazole synthase regulation 1 1 1 DNA to cDNA expression microarray evidence
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex regulation 1 1 1 DNA to cDNA expression microarray evidence
PMC1 YGL006W Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions regulation 1 1 1 chromatin immunoprecipitation-chip evidence
COT1 YOR316C Vacuolar transporter that mediates zinc transport into the vacuole regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GTS1 YGL181W Protein involved in Arf3p regulation and in transcription regulation regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 1 1 1 Affinity Capture-MS
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Synthetic Growth Defect
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
FAR1 YJL157C CDK inhibitor and nuclear anchor genetic 1 1 1 Phenotypic Suppression
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
PPZ1 YML016C Serine/threonine protein phosphatase Z, isoform of Ppz2p genetic 1 1 1 Synthetic Growth Defect
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Negative Genetic
KAR4 YCL055W Transcription factor required for response to pheromones genetic 1 1 1 Phenotypic Suppression
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Synthetic Rescue
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Phenotypic Suppression
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Enhancement
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family physical 1 1 1 Affinity Capture-Western
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 Affinity Capture-MS
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 1 1 1 PCA
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 PCA
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Negative Genetic
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response physical 1 1 1 Two-hybrid
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit genetic 1 1 1 Dosage Rescue
STE2 YFL026W Receptor for alpha-factor pheromone genetic 1 1 1 Phenotypic Suppression
STE4 YOR212W G protein beta subunit genetic 1 1 1 Phenotypic Suppression
STE5 YDR103W Pheromone-responsive MAPK scaffold protein genetic 1 1 1 Phenotypic Suppression
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Suppression
STE11 YLR362W Signal transducing MEK kinase genetic 1 1 1 Phenotypic Suppression
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Synthetic Growth Defect
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Positive Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
RGT1 YKL038W Glucose-responsive transcription factor genetic 1 1 1 Phenotypic Enhancement
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Dosage Rescue
NNK1 YKL171W Protein kinase physical 1 1 1 Biochemical Activity
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Synthetic Rescue
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation physical 1 1 1 Affinity Capture-MS
MSN4 YKL062W Stress-responsive transcriptional activator genetic 1 1 1 Phenotypic Enhancement
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Negative Genetic