Standard name Systematic name Name description Description
SUB1 YMR039C Transcriptional regulator Transcriptional regulator; facilitates elongation through factors that modify RNAP II; role in peroxide resistance involving Rad2p; role in nonhomologous end-joining (NHEJ) of ds breaks in plasmid DNA, but not chromosomal DNA; role in the hyperosmotic stress response through polymerase recruitment at RNAP II and RNAP III genes; negatively regulates sporulation; protein abundance increases in response to DNA replication stress; functionally complemented by human SUB1 (PC4)
Visualize the interactome of SUB1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleus 0.944 0.901 0.943
Cytoplasm NaN NaN 0.051

GFP localization & abundance

GFP localization GFP abundance
nucleus 7820

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SUB1 13 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 8 4 5 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression, Synthetic Rescue, Negative Genetic, Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 5 3 4 Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 5 2 4 Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 4 3 4 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 4 2 4 Dosage Rescue, Negative Genetic, Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Dosage Lethality
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 4 2 2 Dosage Rescue, Dosage Rescue, Synthetic Lethality, Synthetic Lethality
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 4 4 1 Synthetic Growth Defect, Phenotypic Enhancement, Dosage Rescue, Phenotypic Suppression
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 3 1 3 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Co-localization
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 3 2 Phenotypic Enhancement, Synthetic Growth Defect, Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 3 2 2 Co-localization, Affinity Capture-Western, Affinity Capture-Western
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 3 2 2 Synthetic Growth Defect, Negative Genetic, Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CEG1 YGL130W Guanylyltransferase involved in mRNA 5' capping genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 3 3 1 Synthetic Rescue, Synthetic Lethality, Synthetic Growth Defect
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes physical 3 3 1 Affinity Capture-MS, Affinity Capture-Western, Co-localization
RPB7 YDR404C RNA polymerase II subunit B16 physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
LEO1 YOR123C Component of the Paf1 complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
IKI3 YLR384C Subunit of Elongator complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 2 2 2 Synthetic Lethality, Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Synthetic Lethality, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
HHF1 YBR009C Histone H4 genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
HHT1 YBR010W Histone H3 genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
KIN28 YDL108W Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly genetic 2 2 2 Synthetic Lethality, Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 2 2 Phenotypic Suppression, Positive Genetic
NHP6A YPR052C High-mobility group (HMG) protein genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Synthetic Rescue, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 2 2 Negative Genetic, Phenotypic Suppression
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b genetic 2 1 2 Negative Genetic, Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 2 1 2 Negative Genetic, Negative Genetic
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase genetic 2 1 2 Negative Genetic, Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 2 1 2 Negative Genetic, Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
MEX67 YPL169C Poly(A)RNA binding protein involved in nuclear mRNA export genetic 2 1 2 Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 2 Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 1 2 Negative Genetic, Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 2 1 2 Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Positive Genetic, Positive Genetic
PSP1 YDR505C Asn and gln rich protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 2 Negative Genetic, Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 2 1 2 Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 2 1 2 Negative Genetic, Negative Genetic
MSC1 YML128C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 2 Positive Genetic, Positive Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 2 1 2 Negative Genetic, Negative Genetic
IMD2 YHR216W Inosine monophosphate dehydrogenase regulation 2 2 1 chromatin immunoprecipitation-chip evidence, northern blot evidence
RPB4 YJL140W RNA polymerase II subunit B32 physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
RPB4 YJL140W RNA polymerase II subunit B32 genetic 2 2 1 Synthetic Rescue, Dosage Growth Defect
PTA1 YAL043C Subunit of holo-CPF physical 2 2 1 Affinity Capture-Western, Reconstituted Complex
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 2 2 1 Positive Genetic, Negative Genetic
MAF1 YDR005C Highly conserved negative regulator of RNA polymerase III genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 1 Negative Genetic, Positive Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) genetic 2 2 1 Synthetic Rescue, Dosage Lethality
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 2 2 1 Synthetic Growth Defect, Phenotypic Enhancement
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 2 1 Synthetic Rescue, Dosage Growth Defect
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 2 2 1 Reconstituted Complex, Two-hybrid
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 2 2 1 Negative Genetic, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 1 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 1 Positive Genetic, Positive Genetic
KEL1 YHR158C Protein required for proper cell fusion and cell morphology genetic 2 1 1 Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 1 Negative Genetic, Negative Genetic
MRP13 YGR084C Mitochondrial ribosomal protein of the small subunit genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 2 1 1 Negative Genetic, Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 2 1 1 Negative Genetic, Negative Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 2 1 1 Negative Genetic, Negative Genetic
YRB1 YDR002W Ran GTPase binding protein genetic 2 1 1 Negative Genetic, Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex genetic 2 1 1 Negative Genetic, Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 2 1 1 Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 1 Negative Genetic, Negative Genetic
TEF2 YBR118W Translational elongation factor EF-1 alpha genetic 2 1 1 Negative Genetic, Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Negative Genetic
NSE3 YDR288W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Positive Genetic
DRS1 YLL008W Nucleolar DEAD-box protein required for ribosome assembly and function genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Negative Genetic
NAF1 YNL124W RNA-binding protein required for the assembly of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Synthetic Rescue
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Dosage Rescue
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
ECM16 YMR128W Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP physical 1 1 1 Affinity Capture-MS
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Positive Genetic
APL2 YKL135C Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
BUD14 YAR014C Protein involved in bud-site selection genetic 1 1 1 Negative Genetic
CCL1 YPR025C Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Synthetic Growth Defect
CDC55 YGL190C Regulatory subunit B of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
CLP1 YOR250C Component of the cleavage and polyadenylation factor I (CF I) genetic 1 1 1 Positive Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Phenotypic Suppression
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
HST1 YOL068C NAD(+)-dependent histone deacetylase genetic 1 1 1 Phenotypic Suppression
HTB2 YBL002W Histone H2B genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MAK5 YBR142W Essential nucleolar protein genetic 1 1 1 Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ATG26 YLR189C UDP-glucose:sterol glucosyltransferase genetic 1 1 1 Negative Genetic
MRPL8 YJL063C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRPL9 YGR220C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
PAN2 YGL094C Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex genetic 1 1 1 Negative Genetic
PAP1 YKR002W Poly(A) polymerase physical 1 1 1 Reconstituted Complex
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
DOA4 YDR069C Ubiquitin hydrolase genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex genetic 1 1 1 Negative Genetic
NAB6 YML117W Putative RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Co-localization
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
RPB9 YGL070C RNA polymerase II subunit B12.6 genetic 1 1 1 Synthetic Rescue
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
BZZ1 YHR114W SH3 domain protein implicated in regulating actin polymerization genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Co-localization
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Positive Genetic
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Reconstituted Complex
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Negative Genetic
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Synthetic Growth Defect
GLN1 YPR035W Glutamine synthetase (GS) genetic 1 1 1 Negative Genetic
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Positive Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Negative Genetic
FIN1 YDR130C Spindle pole body-related intermediate filament protein physical 1 1 1 Affinity Capture-Western
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Synthetic Growth Defect
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism genetic 1 1 1 Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
CBK1 YNL161W Serine/threonine protein kinase of the the RAM signaling network genetic 1 1 1 Negative Genetic
MSI1 YBR195C Subunit of chromatin assembly factor I (CAF-1) genetic 1 1 1 Negative Genetic
PTP3 YER075C Phosphotyrosine-specific protein phosphatase genetic 1 1 1 Negative Genetic
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
DIA2 YOR080W Origin-binding F-box protein genetic 1 1 1 Positive Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Synthetic Rescue
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 1 1 1 Negative Genetic
ICP55 YER078C Mitochondrial aminopeptidase genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
NUP2 YLR335W Nucleoporin involved in nucleocytoplasmic transport genetic 1 1 1 Negative Genetic
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
FKH2 YNL068C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
EAP1 YKL204W eIF4E-associated protein, competes with eIF4G for binding to eIF4E genetic 1 1 1 Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Positive Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 1 1 1 Positive Genetic
MCM10 YIL150C Essential chromatin-associated protein genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Negative Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
COQ5 YML110C 2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase genetic 1 1 1 Negative Genetic
CHA4 YLR098C DNA binding transcriptional activator genetic 1 1 1 Negative Genetic
AIM7 YDR063W Protein that interacts with Arp2/3 complex genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Positive Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
HUA1 YGR268C Cytoplasmic protein containing a zinc finger domain genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
RNA15 YGL044C Component of the cleavage and polyadenylation factor I (CF I) physical 1 1 1 Reconstituted Complex
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
HOT1 YMR172W Transcription factor for glycerol biosynthetic genes genetic 1 1 1 Synthetic Growth Defect
SFH1 YLR321C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
SKO1 YNL167C Basic leucine zipper transcription factor of the ATF/CREB family genetic 1 1 1 Positive Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways genetic 1 1 1 Negative Genetic
BDP1 YNL039W Essential subunit of RNA polymerase III transcription factor (TFIIIB) physical 1 1 1 Far Western
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit physical 1 1 1 Affinity Capture-MS
RPS7A YOR096W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HXK2 YGL253W Hexokinase isoenzyme 2 genetic 1 1 1 Synthetic Rescue
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Positive Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Positive Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
GAL80 YML051W Transcriptional regulator involved in the repression of GAL genes genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Synthetic Growth Defect
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase physical 1 1 1 Affinity Capture-Western
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Positive Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
CHS5 YLR330W Component of the exomer complex genetic 1 1 1 Negative Genetic
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
RPL31A YDL075W Ribosomal 60S subunit protein L31A physical 1 1 1 Affinity Capture-MS
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
NOP8 YOL144W Nucleolar protein required for 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
RPL28 YGL103W Ribosomal 60S subunit protein L28 genetic 1 1 1 Negative Genetic
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 1 1 1 Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Negative Genetic
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP physical 1 1 1 Two-hybrid
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 1 1 1 Positive Genetic
IRC22 YEL001C Protein of unknown function genetic 1 1 1 Negative Genetic
PDC2 YDR081C Transcription factor for thiamine-regulated genes genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ORC4 YPR162C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
MDM36 YPR083W Mitochondrial protein genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
COA3 YJL062W-A Mitochondrial protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 1 1 1 Negative Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
RPL26A YLR344W Ribosomal 60S subunit protein L26A physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SUB1 YMR039C Transcriptional regulator physical 1 1 1 Far Western
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Far Western
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Far Western
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Phenotypic Suppression
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Positive Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
SUT2 YPR009W Zn2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
ZAP1 YJL056C Zinc-regulated transcription factor genetic 1 1 1 Positive Genetic
URE2 YNL229C Nitrogen catabolite repression transcriptional regulator genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 1 1 1 Negative Genetic
YKL222C YKL222C Protein of unknown function genetic 1 1 1 Negative Genetic
TYE7 YOR344C Serine-rich protein that contains a bHLH DNA binding motif genetic 1 1 1 Positive Genetic
TFA1 YKL028W TFIIE large subunit genetic 1 1 1 Synthetic Growth Defect
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
TAF10 YDR167W Subunit (145 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Positive Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
SVL3 YPL032C Protein of unknown function genetic 1 1 1 Positive Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Positive Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Positive Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
THS1 YIL078W Threonyl-tRNA synthetase genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
YAE1 YJR067C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
TCD1 YHR003C tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Negative Genetic
TMH11 YJR085C Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
VPS25 YJR102C Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
YLL066W-B YLL066W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
SXM1 YDR395W Nuclear transport factor (karyopherin) genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 genetic 1 1 1 Negative Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
XPT1 YJR133W Xanthine-guanine phosphoribosyl transferase genetic 1 1 1 Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 1 1 1 Negative Genetic
TOM7 YNL070W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
SWM2 YNR004W Protein with a role in snRNA and snoRNA cap trimethylation genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) genetic 1 1 1 Negative Genetic
YPL039W YPL039W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Positive Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
RTT106 YNL206C Histone chaperone genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 genetic 1 1 1 Positive Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SNX3 YOR357C Sorting nexin for late-Golgi enzymes genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Negative Genetic
MAL13 YGR288W MAL-activator protein genetic 1 1 1 Negative Genetic
COS7 YDL248W Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
COX7 YMR256C Subunit VII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Negative Genetic
DFG10 YIL049W Probable polyprenol reductase genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Positive Genetic
STP2 YHR006W Transcription factor genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
FMC1 YIL098C Mitochondrial matrix protein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
DPI8 YJL133C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 1 1 1 Negative Genetic
ERG8 YMR220W Phosphomevalonate kinase genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Positive Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP genetic 1 1 1 Negative Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Positive Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase physical 1 1 1 Affinity Capture-MS
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 1 1 1 Negative Genetic
RRT6 YGL146C Integral membrane protein, member of the p24 family genetic 1 1 1 Negative Genetic
QRI7 YDL104C Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Negative Genetic
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response genetic 1 1 1 Synthetic Growth Defect
RTC6 YPL183W-A Protein involved in translation genetic 1 1 1 Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
SLO1 YER180C-A Protein interacting with Arl3p genetic 1 1 1 Negative Genetic
RNP1 YLL046C Ribonucleoprotein that contains two RNA recognition motifs (RRM) genetic 1 1 1 Negative Genetic