BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
18 |
6 |
11 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Co-purification, Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
9 |
3 |
8 |
Positive Genetic, Positive Genetic, Synthetic Growth Defect, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Dosage Rescue, Positive Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
8 |
3 |
8 |
Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
8 |
2 |
7 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
8 |
2 |
7 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
7 |
3 |
6 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
7 |
2 |
6 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
7 |
2 |
6 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
6 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
6 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
6 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
6 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
6 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
5 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
5 |
2 |
5 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
5 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
5 |
2 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
5 |
2 |
4 |
Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic, Positive Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
5 |
2 |
4 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SAP155 |
YFR040W |
Protein required for function of the Sit4p protein phosphatase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
5 |
1 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VPS74 |
YDR372C |
Golgi PI4K effector, PtdIns4P sensor, and retention receptor |
genetic |
5 |
4 |
3 |
Negative Genetic, Negative Genetic, Dosage Rescue, Synthetic Growth Defect, Phenotypic Enhancement |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
5 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
5 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Dosage Rescue, Negative Genetic, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
5 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
4 |
3 |
4 |
Synthetic Growth Defect, Negative Genetic, Phenotypic Suppression, Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
4 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
4 |
2 |
4 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
4 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Rescue |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Proximity Label-MS, Affinity Capture-Western, Affinity Capture-MS |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
4 |
2 |
3 |
Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
4 |
2 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CUP9 |
YPL177C |
Homeodomain-containing transcriptional repressor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
4 |
4 |
2 |
Affinity Capture-Western, Co-purification, Biochemical Activity, Affinity Capture-MS |
LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
4 |
3 |
2 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ENT4 |
YLL038C |
Protein of unknown function |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SCS3 |
YGL126W |
Protein required for normal ER membrane biosynthesis in response to ER |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
3 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
OPY1 |
YBR129C |
Protein of unknown function |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PPG1 |
YNR032W |
Serine protein phosphatase involved in formation of FAR complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC17 |
YBL050W |
Alpha-SNAP cochaperone |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DNM1 |
YLL001W |
Dynamin-related GTPase involved in mitochondrial organization |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MSN5 |
YDR335W |
Karyopherin |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
GPB2 |
YAL056W |
Multistep regulator of cAMP-PKA signaling |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRM8 |
YDL201W |
Catalytic subunit of a tRNA methyltransferase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YGR016W |
YGR016W |
Putative protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ANR2 |
YKL047W |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PMT6 |
YGR199W |
Protein O-mannosyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRM82 |
YDR165W |
Noncatalytic subunit of a tRNA methyltransferase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TMH18 |
YPR098C |
Mitochondrial protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
3 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Co-fractionation |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Biochemical Activity |
ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
physical |
3 |
2 |
1 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ABF2 |
YMR072W |
Mitochondrial DNA-binding protein |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Positive Genetic |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
DEF1 |
YKL054C |
RNAPII degradation factor |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CHA4 |
YLR098C |
DNA binding transcriptional activator |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
genetic |
2 |
2 |
2 |
Dosage Rescue, Phenotypic Suppression |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
2 |
2 |
2 |
Co-purification, Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
genetic |
2 |
2 |
2 |
Dosage Rescue, Phenotypic Suppression |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
INP51 |
YIL002C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Phenotypic Enhancement |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CEX1 |
YOR112W |
Component of nuclear aminoacylation-dependent tRNA export pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RTT10 |
YPL183C |
WD40 domain-containing protein involved in endosomal recycling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAF40 |
YNL288W |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MLH1 |
YMR167W |
Protein required for mismatch repair in mitosis and meiosis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MLC1 |
YGL106W |
Essential light chain for Myo1p |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BCY1 |
YIL033C |
Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CYM1 |
YDR430C |
Lysine-specific metalloprotease of the pitrilysin family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DBF20 |
YPR111W |
Ser/Thr kinase involved in late nuclear division |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SOR2 |
YDL246C |
Sorbitol dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPB1 |
YOR371C |
Multistep regulator of cAMP-PKA signaling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFA2 |
YKR062W |
TFIIE small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MBA1 |
YBR185C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKR041W |
YKR041W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
WHI3 |
YNL197C |
RNA binding protein that modulates mRNA stability |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OCA4 |
YCR095C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AGE1 |
YDR524C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NPR1 |
YNL183C |
Protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SUR7 |
YML052W |
Plasma membrane protein, component of eisosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NCS2 |
YNL119W |
Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BER1 |
YLR412W |
Protein involved in microtubule-related processes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBC13 |
YDR092W |
E2 ubiquitin-conjugating enzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
AAT1 |
YKL106W |
Mitochondrial aspartate aminotransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRX4 |
YPL168W |
Protein that associates with mitochondrial ribosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAU10 |
YDR542W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
regulation |
2 |
2 |
1 |
co-immunoprecipitation evidence, qualitative western immunoblotting evidence |
PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Biochemical Activity |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Rescue |
RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-Western |
ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ADH6 |
YMR318C |
NADPH-dependent medium chain alcohol dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
SSS1 |
YDR086C |
Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YJR120W |
YJR120W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YPT1 |
YFL038C |
Rab family GTPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HSP78 |
YDR258C |
Oligomeric mitochondrial matrix chaperone |
physical |
2 |
1 |
1 |
Affinity Capture-MS, Affinity Capture-MS |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TOA2 |
YKL058W |
TFIIA small subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
1 |
1 |
1 |
Positive Genetic |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
physical |
1 |
1 |
1 |
Co-purification |
TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRX1 |
YOL077C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL17A |
YKL180W |
Ribosomal 60S subunit protein L17A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL30 |
YGL030W |
Ribosomal 60S subunit protein L30 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL32 |
YBL092W |
Ribosomal 60S subunit protein L32 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMB1 |
YER029C |
Core Sm protein Sm B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOC2 |
YOR206W |
Protein involved in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KES1 |
YPL145C |
Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAT3 |
YPR131C |
Catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THO2 |
YNL139C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD1 |
YBR119W |
U1 snRNP A protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTA1 |
YAL043C |
Subunit of holo-CPF |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOI2 |
YER114C |
Protein involved in polar growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Biochemical Activity |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EMP24 |
YGL200C |
Component of the p24 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT4 |
YDL143W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KGD2 |
YDR148C |
Dihydrolipoyl transsuccinylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV4 |
YHR059W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCL1 |
YBL024W |
S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ITC1 |
YGL133W |
Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPR4 |
YLR449W |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDA1 |
YER178W |
E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BLM10 |
YFL007W |
Proteasome activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAA1 |
YDR071C |
Polyamine acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTC4 |
YBR125C |
Cytoplasmic type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD16 |
YBR114W |
Nucleotide excision repair (NER) protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
RAD23 |
YEL037C |
Protein with ubiquitin-like N terminus |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GCN20 |
YFR009W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD3 |
YER171W |
5' to 3' DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA12 |
YJR063W |
RNA polymerase I subunit A12.2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL2A |
YFR031C-A |
Ribosomal 60S subunit protein L2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLH2 |
YLR035C |
Protein involved in mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGI1 |
YBR196C |
Glycolytic enzyme phosphoglucose isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC13 |
YLR208W |
Structural component of 3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM1 |
YLR180W |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM25 |
YJL201W |
Endocytic site protein required for stress-induced cell elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE3 |
YPR069C |
Spermidine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRN1 |
YLR429W |
Coronin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFB1 |
YAL003W |
Translation elongation factor 1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFA1 |
YKL028W |
TFIIE large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBG1 |
YAL036C |
Member of the DRG family of GTP-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Co-purification |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RGC1 |
YPR115W |
Putative regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA20 |
YER007C-A |
Protein of unknown function that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAR2 |
YLR438W |
L-ornithine transaminase (OTAse) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IRA2 |
YOL081W |
GTPase-activating protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
physical |
1 |
1 |
1 |
Biochemical Activity |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC53 |
YFL045C |
Phosphomannomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCL7 |
YIL050W |
Pho85p cyclin of the Pho80p subfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGM2 |
YMR105C |
Phosphoglucomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS3 |
YHL011C |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KDX1 |
YKL161C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET9 |
YBL030C |
Major ADP/ATP carrier of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MAE1 |
YKL029C |
Mitochondrial malic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRO3 |
YER023W |
Delta 1-pyrroline-5-carboxylate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDS1 |
YDR113C |
Securin |
physical |
1 |
1 |
1 |
Biochemical Activity |
MSI1 |
YBR195C |
Subunit of chromatin assembly factor I (CAF-1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC6 |
YLR383W |
Subunit of the SMC5-SMC6 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GRX1 |
YCL035C |
Glutathione-dependent disulfide oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNP1 |
YGL068W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEG1 |
YMR086W |
Component of eisosome required for proper eisosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Positive Genetic |
AHC1 |
YOR023C |
Subunit of the Ada histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI22 |
YPR121W |
Protein with similarity to hydroxymethylpyrimidine phosphate kinases |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASR1 |
YPR093C |
Ubiquitin ligase that modifies and regulates RNA Pol II |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD26 |
YJR035W |
Protein involved in transcription-coupled nucleotide excision repair |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIN5 |
YOR028C |
Basic leucine zipper (bZIP) transcription factor of the yAP-1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APM4 |
YOL062C |
Cargo-binding mu subunit of AP-2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSL1 |
YNL258C |
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE8 |
YDR408C |
Phosphoribosyl-glycinamide transformylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ACA1 |
YER045C |
ATF/CREB family basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR8 |
YLR266C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FOB1 |
YDR110W |
Nucleolar protein that binds the rDNA replication fork barrier site |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MRX16 |
YDR132C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB2 |
YMR053C |
Protein that interacts with Sin3p in a two-hybrid assay |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUT3 |
YKL015W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TTI1 |
YKL033W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIB4 |
YOL143C |
Lumazine synthase (DMRL synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MDR1 |
YGR100W |
Cytoplasmic GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS4A |
YJR145C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NFI1 |
YOR156C |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL9A |
YGL147C |
Ribosomal 60S subunit protein L9A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS24B |
YIL069C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRP1 |
YHR146W |
Protein that binds to cruciform DNA structures |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC7 |
YLR385C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS3 |
YPL116W |
Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO4 |
YFR034C |
Basic helix-loop-helix (bHLH) transcription factor of the myc-family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS8B |
YER102W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSC1 |
YJR045C |
Hsp70 family ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCY1 |
YJL204C |
F-box protein involved in recycling endocytosed proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAV2 |
YDR202C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN1 |
YOR349W |
Tubulin folding factor D involved in beta-tubulin (Tub2p) folding |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO2 |
YDL106C |
Homeobox transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIL1 |
YOL031C |
Nucleotide exchange factor for the ER lumenal Hsp70 chaperone Kar2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DAL80 |
YKR034W |
Negative regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCH1 |
YNL281W |
Heat shock protein regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEA1 |
YOR337W |
Ty1 enhancer activator involved in Ty enhancer-mediated transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM2 |
YDR502C |
S-adenosylmethionine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP1 |
YBL099W |
Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OAF1 |
YAL051W |
Oleate-activated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDI1 |
YDL135C |
Rho GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERT1 |
YBR239C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSL5 |
YLR116W |
Component of commitment complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDL1 |
YLR188W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDR12 |
YPL058C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFB4 |
YPR056W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL18B |
YNL301C |
Ribosomal 60S subunit protein L18B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23B |
YPR132W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRF1 |
YDR223W |
Transcriptional corepressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU13 |
YEL026W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL7A |
YGL076C |
Ribosomal 60S subunit protein L7A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19B |
YBL027W |
Ribosomal 60S subunit protein L19B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL21A |
YBR191W |
Ribosomal 60S subunit protein L21A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL27B |
YDR471W |
Ribosomal 60S subunit protein L27B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL36B |
YPL249C-A |
Ribosomal 60S subunit protein L36B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDP3 |
YLR455W |
Component of the NuA3b histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASG7 |
YJL170C |
Protein that regulates signaling from G protein beta subunit Ste4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GTB1 |
YDR221W |
Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
JHD2 |
YJR119C |
JmjC domain family histone demethylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUP1 |
YOR138C |
Protein that regulates ubiquitination of Rsp5p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
physical |
1 |
1 |
1 |
Biochemical Activity |
DIC1 |
YLR348C |
Mitochondrial dicarboxylate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIM1 |
YCR028C-A |
ssDNA-binding protein essential for mitochondrial genome maintenance |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIP1 |
YBR067C |
Major cell wall mannoprotein with possible lipase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IFA38 |
YBR159W |
Microsomal beta-keto-reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOL2 |
YCR073W-A |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP14 |
YDL092W |
Signal recognition particle (SRP) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAT5 |
YOR253W |
Subunit of protein N-terminal acetyltransferase NatA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
GID11 |
YLR149C |
Substrate receptor of the glucose-induced degradation-deficient (GID) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GUK1 |
YDR454C |
Guanylate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DDR48 |
YMR173W |
DNA damage-responsive protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZEO1 |
YOL109W |
Peripheral membrane protein of the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA2 |
YJL130C |
Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR214C-B |
YHR214C-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR158W-B |
YPR158W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YML045W |
YML045W |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URB1 |
YKL014C |
Protein required for the normal accumulation of 25S and 5.8S rRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP9 |
YHR196W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YNL040W |
YNL040W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR045C |
YMR045C |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YBL005W-B |
YBL005W-B |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA6 |
YLR447C |
Subunit d of the V0 integral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCR016W |
YCR016W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA1 |
YKL216W |
Dihydroorotate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URN1 |
YPR152C |
Protein of unknown function containing WW and FF domains |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YAK1 |
YJL141C |
Serine-threonine protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ULP2 |
YIL031W |
Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins |
genetic |
1 |
1 |
1 |
Dosage Rescue |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
WAR1 |
YML076C |
Homodimeric Zn2Cys6 zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKU70 |
YMR284W |
Subunit of the telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAL064W |
YAL064W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID24 |
YBR105C |
GID Complex regulatory subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPT10 |
YBR264C |
Rab family GTP-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL157C |
YDL157C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR131C |
YDR131C |
F-box protein subunit of SCF ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI4 |
YDL224C |
Putative RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR035C |
YGR035C |
Putative protein of unknown function, potential Cdc28p substrate |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIL152W |
YIL152W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL077W-B |
YJL077W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLL056C |
YLL056C |
NADH-dependent aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UCC1 |
YLR224W |
F-box protein and component of SCF ubiquitin ligase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML053C |
YML053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL108C |
YNL108C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL115C |
YNL115C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL057W |
YOL057W |
Dipeptidyl-peptidase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET12 |
YPL023C |
Protein with MTHFR activity in vitro |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
LYS14 |
YDR034C |
Transcriptional activator involved in regulating lysine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTP1 |
YBR291C |
Mitochondrial inner membrane citrate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIS2 |
YKR072C |
Negative regulatory subunit of protein phosphatase 1 (Ppz1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM26 |
YKL037W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAS1 |
YKL182W |
Beta subunit of fatty acid synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWA2 |
YDR320C |
Auxilin-like protein involved in vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFK26 |
YIL107C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO13 |
YDL236W |
Conserved phosphatase acting as a metabolite repair enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL12A |
YEL054C |
Ribosomal 60S subunit protein L12A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
NVJ3 |
YDR179W-A |
Protein with a potential role in tethering ER and vacuoles |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSS18 |
YPR134W |
Nuclear encoded protein needed for splicing of mitochondrial intron |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL20A |
YMR242C |
Ribosomal 60S subunit protein L20A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS22B |
YLR367W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14B |
YJL191W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO2 |
YGL148W |
Bifunctional chorismate synthase and flavin reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL34A |
YER056C-A |
Ribosomal 60S subunit protein L34A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRE8 |
YLR047C |
Protein with sequence similarity to iron/copper reductases |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP1 |
YDR505C |
Asn and gln rich protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNH70 |
YGR276C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TMA22 |
YJR014W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCL1 |
YPL056C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMF1 |
YOL122C |
Divalent metal ion transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18B |
YML026C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASP1 |
YDR321W |
Cytosolic L-asparaginase, involved in asparagine catabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THR1 |
YHR025W |
Homoserine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TED1 |
YIL039W |
GPI-glycan remodelase |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIB3 |
YDR487C |
3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXT3 |
YDR345C |
Low affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDD4 |
YPR022C |
Putative transcription factor, as suggested by computational analysis |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCY1 |
YGL083W |
Putative kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TYR1 |
YBR166C |
Prephenate dehydrogenase involved in tyrosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPI1 |
YIL119C |
Transcription factor, allelic differences between S288C and Sigma1278b |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLO127 |
YJR039W |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAL9 |
YOL089C |
Putative transcription factor containing a zinc finger |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRX2 |
YDR513W |
Cytoplasmic glutaredoxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG41 |
YPL250C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
BSC4 |
YNL269W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Positive Genetic |
STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APS3 |
YJL024C |
Small subunit of the clathrin-associated adaptor complex AP-3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROM1 |
YGR070W |
Guanine nucleotide exchange factor (GEF) for Rho1p |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR2 |
YPL098C |
Subunit of the TIM23 translocase complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
NGL1 |
YOL042W |
Putative endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RKR1 |
YMR247C |
RING domain E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM38 |
YLR299W |
Gamma-glutamyltranspeptidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCE101 |
YJL205C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX11 |
YPL041C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ODC2 |
YOR222W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBH1 |
YJL181W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET20 |
YPL159C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTC4 |
YBR255W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
IZH1 |
YDR492W |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHM7 |
YOL084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPS2 |
YDR522C |
Protein expressed during sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSP2 |
YOR242C |
Sporulation specific protein that localizes to the spore wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
STP4 |
YDL048C |
Protein containing a Kruppel-type zinc-finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPP2 |
YEL016C |
Nucleotide pyrophosphatase/phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMS1 |
YDR105C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO23 |
YBR250W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUT2 |
YPR009W |
Zn2Cys6 family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |