Standard name Systematic name Name description Description
SMB1 YER029C Core Sm protein Sm B Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'
Visualize the interactome of SMB1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.074 0.107 NaN
Nucleus 0.960 0.932 0.947

GFP localization & abundance

GFP localization GFP abundance
nucleus 861

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SMB1 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 8 3 7 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
SMD1 YGR074W Core Sm protein Sm D1 physical 6 1 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein physical 6 3 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-crystal Structure
LEA1 YPL213W Component of U2 snRNP complex physical 6 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 5 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing physical 5 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome physical 5 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
NAM8 YHR086W RNA binding protein, component of the U1 snRNP protein physical 5 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CEF1 YMR213W Essential splicing factor physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
SMD3 YLR147C Core Sm protein Sm D3 physical 4 2 4 Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
SPP381 YBR152W mRNA splicing factor, component of U4/U6.U5 tri-snRNP physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LSM4 YER112W Lsm (Like Sm) protein physical 4 2 3 Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS
SPP382 YLR424W Essential protein that forms a dimer with Ntr2p physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNU71 YGR013W Component of U1 snRNP required for mRNA splicing via spliceosome physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP40 YKL012W U1 snRNP protein involved in splicing physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LUC7 YDL087C Essential protein associated with the U1 snRNP complex physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP31 YGR091W Splicing factor physical 4 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 3 2 3 Affinity Capture-MS, Co-purification, Affinity Capture-MS
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SMX2 YFL017W-A Core Sm protein Sm G physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SMX3 YPR182W Core Sm protein Sm F physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNU56 YDR240C Component of U1 snRNP required for mRNA splicing via spliceosome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SMD2 YLR275W Core Sm protein Sm D2 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SNP1 YIL061C Component of U1 snRNP required for mRNA splicing via spliceosome physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LSM3 YLR438C-A Lsm (Like Sm) protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP4 YPR178W Splicing factor physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP6 YBR055C Splicing factor physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PRP11 YDL043C Subunit of the SF3a splicing factor complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase physical 2 2 2 Reconstituted Complex, Affinity Capture-Western
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
CWC23 YGL128C Component of a complex containing Cef1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP43 YGL120C RNA helicase in the DEAH-box family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SME1 YOR159C Core Sm protein Sm E physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU23 YDL098C Component of the U4/U6.U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SYF1 YDR416W Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP3 YDR473C Splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP39 YML046W U1 snRNP protein involved in splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
AAR2 YBL074C Component of the U5 snRNP complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSH155 YMR288W U2-snRNP associated splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LSM2 YBL026W Lsm (Like Sm) protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DIB1 YPR082C 17-kDa component of the U4/U6aU5 tri-snRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP21 YJL203W Subunit of the SF3a splicing factor complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP9 YDL030W Subunit of the SF3a splicing factor complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RSE1 YML049C Protein involved in pre-mRNA splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MSL1 YIR009W U2B component of U2 snRNP physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP42 YDR235W U1 snRNP protein involved in splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSH49 YOR319W U2-snRNP associated splicing factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CWC21 YDR482C Protein involved in RNA splicing by the spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LSM8 YJR022W Lsm (Like Sm) protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SMD1 YGR074W Core Sm protein Sm D1 genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
SMX2 YFL017W-A Core Sm protein Sm G genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SMX3 YPR182W Core Sm protein Sm F genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
SME1 YOR159C Core Sm protein Sm E genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
SMD2 YLR275W Core Sm protein Sm D2 genetic 2 2 1 Synthetic Growth Defect, Synthetic Lethality
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
NRG1 YDR043C Transcriptional repressor regulation 1 1 1 DNA to cDNA expression microarray evidence
RSF2 YJR127C Zinc-finger protein regulation 1 1 1 DNA to cDNA expression microarray evidence
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways regulation 1 1 1 DNA to cDNA expression microarray evidence
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger regulation 1 1 1 DNA to cDNA expression microarray evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
STP2 YHR006W Transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
HIR1 YBL008W Subunit of the HIR complex regulation 1 1 1 DNA to cDNA expression microarray evidence
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis regulation 1 1 1 DNA to cDNA expression microarray evidence
TOD6 YBL054W PAC motif binding protein involved in rRNA and ribosome biogenesis regulation 1 1 1 DNA to cDNA expression microarray evidence
CDC40 YDR364C Pre-mRNA splicing factor physical 1 1 1 Affinity Capture-MS
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
ECM2 YBR065C Pre-mRNA splicing factor physical 1 1 1 Affinity Capture-MS
PRP45 YAL032C Protein required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes physical 1 1 1 Affinity Capture-MS
SMD3 YLR147C Core Sm protein Sm D3 genetic 1 1 1 Synthetic Lethality
SWT21 YNL187W Protein involved in mRNA splicing physical 1 1 1 Two-hybrid
YNL092W YNL092W S-adenosylmethionine-dependent protein methyltransferase physical 1 1 1 Affinity Capture-MS
YJR084W YJR084W Protein that forms a complex with Thp3p physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
URN1 YPR152C Protein of unknown function containing WW and FF domains physical 1 1 1 Affinity Capture-MS
SNU13 YEL026W RNA binding protein physical 1 1 1 Affinity Capture-MS
SYF2 YGR129W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
YSF3 YNL138W-A Component of the SF3b subcomplex of the U2 snRNP physical 1 1 1 Affinity Capture-MS
SRP1 YNL189W Karyopherin alpha homolog physical 1 1 1 Affinity Capture-MS
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
SPB4 YFL002C Putative ATP-dependent RNA helicase physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
NTR2 YKR022C Essential protein that forms a dimer with Ntr1p physical 1 1 1 Affinity Capture-MS
NHP2 YDL208W Protein related to mammalian high mobility group (HMG) proteins physical 1 1 1 Affinity Capture-MS
LSM5 YER146W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
LSM6 YDR378C Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
CDC33 YOL139C Translation initiation factor eIF4E physical 1 1 1 Affinity Capture-MS
MUD1 YBR119W U1 snRNP A protein genetic 1 1 1 Synthetic Growth Defect
KAP95 YLR347C Karyopherin beta physical 1 1 1 Affinity Capture-MS
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
LHP1 YDL051W RNA binding protein required for maturation of tRNA and U6 snRNA physical 1 1 1 Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
LSM7 YNL147W Lsm (Like Sm) protein physical 1 1 1 Affinity Capture-MS
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
LIN1 YHR156C Non-essential component of U5 snRNP physical 1 1 1 Affinity Capture-MS
PUB1 YNL016W Poly (A)+ RNA-binding protein physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs physical 1 1 1 Affinity Capture-MS
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Synthetic Growth Defect
SIP1 YDR422C One of three alternate beta-subunits of the Snf1p kinase complex physical 1 1 1 Two-hybrid
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme physical 1 1 1 PCA
PRP38 YGR075C Unique component of the U4/U6.U5 tri-snRNP particle physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Synthetic Rescue
LSM12 YHR121W Protein of unknown function that may function in RNA processing physical 1 1 1 Affinity Capture-MS
BUD13 YGL174W Subunit of the RES complex physical 1 1 1 Affinity Capture-MS
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay physical 1 1 1 Affinity Capture-MS
ISY1 YJR050W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
NTC20 YBR188C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Synthetic Growth Defect
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 1 1 1 Reconstituted Complex
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Affinity Capture-MS
MSL5 YLR116W Component of commitment complex physical 1 1 1 Affinity Capture-MS
CCC1 YLR220W Vacuolar Fe2+/Mn2+ transporter physical 1 1 1 Two-hybrid
PBP4 YDL053C Pbp1p binding protein physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex physical 1 1 1 Affinity Capture-MS
SEH1 YGL100W Subunit of the Nup84 nuclear pore and SEACAT subcomplexes physical 1 1 1 Affinity Capture-MS
CWC27 YPL064C Component of a complex containing Cef1p physical 1 1 1 Affinity Capture-MS