Standard name Systematic name Name description Description
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing Spliceosome-associated protein that is required for pre-mRNA splicing; necessary for Prp2p function at the first catalytic step of splicing; has similarity to S. pombe Cwf22p; CWC22 is an essential protein
Visualize the interactome of CWC22
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.101 NaN NaN
Nucleus 0.947 0.945 0.975

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 3260

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
CWC22 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CEF1 YMR213W Essential splicing factor physical 6 3 5 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification
PRP8 YHR165C Component of U4/U6-U5 snRNP complex physical 3 1 2 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
SAC3 YDR159W mRNA export factor genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CWC2 YDL209C Member of the NineTeen Complex (NTC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP45 YAL032C Protein required for pre-mRNA splicing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRP19 YLL036C Splicing factor associated with the spliceosome physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CEF1 YMR213W Essential splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Negative Genetic, Negative Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 2 1 1 Negative Genetic, Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SLU7 YDR088C RNA splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 2 1 1 Negative Genetic, Negative Genetic
PRP18 YGR006W Splicing factor and component of snRNP U5 genetic 2 1 1 Negative Genetic, Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 2 1 1 Negative Genetic, Negative Genetic
RSE1 YML049C Protein involved in pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 2 1 1 Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
PRP4 YPR178W Splicing factor genetic 2 1 1 Negative Genetic, Negative Genetic
IST3 YIR005W Component of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 2 1 1 Negative Genetic, Negative Genetic
PML1 YLR016C Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 2 1 1 Negative Genetic, Negative Genetic
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 2 1 1 Negative Genetic, Negative Genetic
SNU66 YOR308C Component of the U4/U6.U5 snRNP complex genetic 2 1 1 Negative Genetic, Negative Genetic
BUD13 YGL174W Subunit of the RES complex genetic 2 1 1 Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Synthetic Lethality
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p physical 1 1 1 Affinity Capture-MS
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
ARC18 YLR370C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
ARP2 YDL029W Essential component of the Arp2/3 complex genetic 1 1 1 Synthetic Growth Defect
ATP11 YNL315C Molecular chaperone genetic 1 1 1 Negative Genetic
CDC45 YLR103C DNA replication initiation factor genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CIP1 YPL014W Cyclin-dependent kinase inhibitor genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing physical 1 1 1 Affinity Capture-MS
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
SCM4 YGR049W Mitochondrial outer membrane protein of unknown function physical 1 1 1 Two-hybrid
SNT309 YPR101W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
SNT309 YPR101W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
HSH155 YMR288W U2-snRNP associated splicing factor physical 1 1 1 Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
SYF1 YDR416W Member of the NineTeen Complex (NTC) physical 1 1 1 Affinity Capture-MS
SYF1 YDR416W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase physical 1 1 1 Affinity Capture-MS
PRP16 YKR086W DEAH-box RNA helicase physical 1 1 1 Affinity Capture-MS
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SMB1 YER029C Core Sm protein Sm B physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
VAB2 YEL005C Subunit of the BLOC-1 complex involved in endosomal maturation physical 1 1 1 Two-hybrid
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 1 1 1 Negative Genetic
LRP1 YHR081W Nuclear exosome-associated nucleic acid binding protein genetic 1 1 1 Synthetic Growth Defect
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis genetic 1 1 1 Synthetic Growth Defect
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Synthetic Lethality
RPS17A YML024W Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Synthetic Lethality
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Positive Genetic
DUO1 YGL061C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Positive Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Positive Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Positive Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Positive Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Positive Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Positive Genetic
YCL068C YCL068C Putative protein of unknown function genetic 1 1 1 Positive Genetic
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Positive Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
SAD1 YFR005C Conserved zinc-finger domain protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Negative Genetic
CWC24 YLR323C General splicing factor genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Negative Genetic
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase genetic 1 1 1 Negative Genetic
UGA4 YDL210W GABA (gamma-aminobutyrate) permease genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
TAD1 YGL243W tRNA-specific adenosine deaminase genetic 1 1 1 Negative Genetic
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
SWE1 YJL187C Protein kinase that regulates the G2/M transition genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
PIR3 YKL163W O-glycosylated covalently-bound cell wall protein genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
RAX2 YLR084C Protein required for the maintenance of bud site selection genetic 1 1 1 Negative Genetic
SPE4 YLR146C Spermine synthase genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 1 1 1 Negative Genetic
CWC27 YPL064C Component of a complex containing Cef1p genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 1 1 1 Negative Genetic
SLI15 YBR156C Subunit of the conserved chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MSS2 YDL107W Peripherally bound inner membrane protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
DPI8 YJL133C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
YKR075C YKR075C Protein of unknown function genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin genetic 1 1 1 Negative Genetic
VPS36 YLR417W Component of the ESCRT-II complex genetic 1 1 1 Negative Genetic
IBD2 YNL164C Component of the BUB2-dependent spindle checkpoint pathway genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
MDH2 YOL126C Cytoplasmic malate dehydrogenase genetic 1 1 1 Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
CTL1 YMR180C RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Negative Genetic
COX13 YGL191W Subunit VIa of cytochrome c oxidase genetic 1 1 1 Negative Genetic