Standard name Systematic name Name description Description
PRI1 YIR008C Subunit of DNA primase Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair
Visualize the interactome of PRI1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1/S 54

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data 197

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PRI1 0 0 0 0 4

Enzyme information

Catalyzed reactions in Yeast8

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex physical 9 5 7 Co-localization, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-Western
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 4 2 4 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 4 3 3 Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex
DDC1 YPL194W DNA damage checkpoint protein genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAE2 YGL175C Endonuclease required for telomere elongation genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 2 2 2 Synthetic Lethality, Negative Genetic
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon physical 2 2 2 Reconstituted Complex, Co-purification
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
PRI2 YKL045W Subunit of DNA primase physical 2 2 2 Co-purification, Affinity Capture-MS
PRI2 YKL045W Subunit of DNA primase genetic 2 2 2 Synthetic Lethality, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 2 2 2 Negative Genetic, Phenotypic Enhancement
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 2 2 Positive Genetic, Negative Genetic
CHD1 YER164W Chromatin remodeler that regulates various aspects of transcription genetic 2 1 2 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
MSH2 YOL090W Protein that binds to DNA mismatches genetic 2 1 2 Negative Genetic, Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
MEC3 YLR288C DNA damage and meiotic pachytene checkpoint protein genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
HST3 YOR025W Sirtuin, histone H3 deacetylase genetic 2 1 2 Negative Genetic, Negative Genetic
CSM3 YMR048W Replication fork associated factor genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SWC3 YAL011W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 2 1 2 Negative Genetic, Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 2 1 2 Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 1 2 Negative Genetic, Negative Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 2 Negative Genetic, Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
ERV29 YGR284C Protein localized to COPII-coated vesicles genetic 2 1 2 Negative Genetic, Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 2 1 Positive Genetic, Negative Genetic
MCM4 YPR019W Essential helicase component of heterohexameric MCM2-7 complexes physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control physical 2 1 1 PCA, PCA
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
NOP58 YOR310C Protein involved in producing mature rRNAs and snoRNAs genetic 1 1 1 Negative Genetic
AIR2 YDL175C RNA-binding subunit of the TRAMP nuclear RNA surveillance complex genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes genetic 1 1 1 Synthetic Lethality
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein genetic 1 1 1 Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
CYR1 YJL005W Adenylate cyclase genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Positive Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 genetic 1 1 1 Positive Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HRP1 YOL123W Subunit of cleavage factor I genetic 1 1 1 Negative Genetic
IOC3 YFR013W Subunit of the Isw1a complex genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-MS
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Positive Genetic
ISW2 YOR304W ATP-dependent DNA translocase involved in chromatin remodeling genetic 1 1 1 Positive Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
GAL11 YOL051W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
LCD1 YDR499W Essential protein required for the DNA integrity checkpoint pathways genetic 1 1 1 Synthetic Lethality
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring physical 1 1 1 Affinity Capture-MS
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Positive Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
PAP1 YKR002W Poly(A) polymerase genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
CWC22 YGR278W Spliceosome-associated protein that is required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
CDC6 YJL194W Essential ATP-binding protein required for DNA replication genetic 1 1 1 Negative Genetic
PPH21 YDL134C Catalytic subunit of protein phosphatase 2A, PP2A genetic 1 1 1 Negative Genetic
HOS2 YGL194C Histone deacetylase and subunit of Set3 and Rpd3L complexes genetic 1 1 1 Positive Genetic
HOS4 YIL112W Subunit of the Set3 complex genetic 1 1 1 Positive Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
IST2 YBR086C Cortical ER protein involved in ER-plasma membrane (PM) tethering genetic 1 1 1 Positive Genetic
MCM2 YBL023C Protein involved in DNA replication physical 1 1 1 Affinity Capture-Western
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
DOT6 YER088C Protein involved in rRNA and ribosome biogenesis genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
HSH49 YOR319W U2-snRNP associated splicing factor genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
FHL1 YPR104C Regulator of ribosomal protein (RP) transcription genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein physical 1 1 1 Affinity Capture-MS
BOP2 YLR267W Protein of unknown function genetic 1 1 1 Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
ISA1 YLL027W Protein required for maturation of mitochondrial [4Fe-4S] proteins genetic 1 1 1 Negative Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 1 1 1 Positive Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Positive Genetic
ASM4 YDL088C FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
ISY1 YJR050W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
NHP6A YPR052C High-mobility group (HMG) protein genetic 1 1 1 Positive Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
AMA1 YGR225W Activator of meiotic anaphase promoting complex (APC/C) genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
KAR9 YPL269W Spindle positioning factor genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Negative Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
FIR1 YER032W Protein involved in 3' mRNA processing genetic 1 1 1 Synthetic Lethality
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Co-localization
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
YRA1 YDR381W Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
RAD24 YER173W Checkpoint protein genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 1 1 1 Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
RPA34 YJL148W RNA polymerase I subunit A34.5 genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
SPP1 YPL138C Subunit of COMPASS (Set1C) genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
SAS4 YDR181C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SAS5 YOR213C Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
TPA1 YER049W Prolyl hydroxylase genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
RNH1 YMR234W Ribonuclease H1 genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Positive Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Positive Genetic
TRF5 YNL299W Non-canonical poly(A) polymerase genetic 1 1 1 Positive Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Positive Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Positive Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Positive Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
SRP40 YKR092C Nucleolar serine-rich protein genetic 1 1 1 Positive Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Positive Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 1 1 1 Positive Genetic
SSF1 YHR066W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Positive Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Positive Genetic
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Positive Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Positive Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Positive Genetic
YNR048W YNR048W Potential noncatalytic subunit for phospholipid translocase Dnf3p genetic 1 1 1 Positive Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Positive Genetic
UNG1 YML021C Uracil-DNA glycosylase genetic 1 1 1 Positive Genetic
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 1 1 1 Synthetic Lethality
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
TTI2 YJR136C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Positive Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Positive Genetic
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Positive Genetic
VPS29 YHR012W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Positive Genetic
PTA1 YAL043C Subunit of holo-CPF genetic 1 1 1 Negative Genetic
PRP5 YBR237W RNA helicase in the DEAD-box family genetic 1 1 1 Negative Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
PRP11 YDL043C Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
STN1 YDR082W Telomere end-binding and capping protein genetic 1 1 1 Negative Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RRN7 YJL025W Component of the core factor (CF) rDNA transcription factor complex genetic 1 1 1 Negative Genetic
PRP21 YJL203W Subunit of the SF3a splicing factor complex genetic 1 1 1 Negative Genetic
URB2 YJR041C Protein required for normal metabolism of the rRNA primary transcript genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
THI80 YOR143C Thiamine pyrophosphokinase genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
TIF6 YPR016C Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SEC8 YPR055W Essential 121 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Negative Genetic
YBL086C YBL086C Protein of unknown function genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
RPL19A YBR084C-A Ribosomal 60S subunit protein L19A genetic 1 1 1 Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
YBR221W-A YBR221W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RRT12 YCR045C Probable subtilisin-family protease genetic 1 1 1 Negative Genetic
SHS1 YDL225W Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
SWF1 YDR126W Palmitoyltransferase that acts on transmembrane proteins genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YGL041C-B YGL041C-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
TWF1 YGR080W Twinfilin genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
YIL134C-A YIL134C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
SEG2 YKL105C Eisosome component genetic 1 1 1 Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VBA1 YMR088C Permease of basic amino acids in the vacuolar membrane genetic 1 1 1 Negative Genetic
YMR155W YMR155W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Negative Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Negative Genetic
YOL166W-A YOL166W-A Protein of unknown function genetic 1 1 1 Negative Genetic
YPL060C-A YPL060C-A TyA Gag protein genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
UCC1 YLR224W F-box protein and component of SCF ubiquitin ligase complexes genetic 1 1 1 Positive Genetic
SMC6 YLR383W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Positive Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
HUB1 YNR032C-A Ubiquitin-like protein modifier genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
OKP1 YGR179C Outer kinetochore protein required for accurate chromosome segregation genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
MEI5 YPL121C Meiosis-specific protein involved in meiotic recombination genetic 1 1 1 Positive Genetic
FUN26 YAL022C High affinity, broad selectivity, nucleoside/nucleobase transporter genetic 1 1 1 Negative Genetic
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
PIP2 YOR363C Autoregulatory, oleate-activated transcription factor genetic 1 1 1 Synthetic Lethality
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b genetic 1 1 1 Negative Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
HST4 YDR191W NAD(+)-dependent protein deacetylase genetic 1 1 1 Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 1 1 1 Negative Genetic
EEB1 YPL095C Acyl-coenzymeA:ethanol O-acyltransferase genetic 1 1 1 Negative Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
AIM34 YMR003W Protein of unknown function genetic 1 1 1 Positive Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Positive Genetic
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase genetic 1 1 1 Negative Genetic
CTS1 YLR286C Endochitinase genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Positive Genetic
LDS2 YOL047C Protein Involved in spore wall assembly genetic 1 1 1 Negative Genetic
ALG11 YNL048W Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
MET22 YOL064C Bisphosphate-3'-nucleotidase genetic 1 1 1 Negative Genetic
PDR18 YNR070W Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Negative Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
PES4 YFR023W Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation genetic 1 1 1 Negative Genetic
ASP3-3 YLR158C Cell-wall L-asparaginase II involved in asparagine catabolism genetic 1 1 1 Negative Genetic