PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
physical |
19 |
5 |
17 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Co-purification, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex |
LSM5 |
YER146W |
Lsm (Like Sm) protein |
physical |
17 |
4 |
13 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
LSM2 |
YBL026W |
Lsm (Like Sm) protein |
physical |
17 |
4 |
13 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
physical |
15 |
4 |
13 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-purification, Two-hybrid, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
physical |
14 |
4 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
14 |
4 |
10 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
physical |
12 |
5 |
10 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-localization, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Co-purification |
SKI2 |
YLR398C |
Ski complex component and putative RNA helicase |
genetic |
10 |
4 |
8 |
Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
10 |
2 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
9 |
1 |
8 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
9 |
3 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
9 |
1 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
9 |
1 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
8 |
1 |
7 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
8 |
2 |
6 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
8 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
8 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
8 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
8 |
2 |
4 |
Negative Genetic, Positive Genetic, Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
7 |
3 |
7 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-RNA |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
7 |
2 |
6 |
Negative Genetic, Positive Genetic, Positive Genetic, Negative Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
CSE2 |
YNR010W |
Subunit of the RNA polymerase II mediator complex |
genetic |
7 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
7 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MUD2 |
YKL074C |
Protein involved in early pre-mRNA splicing |
genetic |
7 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
7 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
6 |
3 |
6 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Positive Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
6 |
2 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
6 |
1 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
6 |
4 |
5 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Positive Genetic, Synthetic Growth Defect |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
6 |
2 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
6 |
2 |
5 |
Synthetic Rescue, Positive Genetic, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Synthetic Rescue |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
6 |
2 |
5 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
6 |
1 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
6 |
1 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SKI7 |
YOR076C |
GTP-binding protein that couples the Ski complex and exosome |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LIN1 |
YHR156C |
Non-essential component of U5 snRNP |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
5 |
2 |
5 |
Positive Genetic, Positive Genetic, Dosage Growth Defect, Positive Genetic, Positive Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
5 |
2 |
5 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
5 |
1 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
5 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
5 |
3 |
4 |
Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Positive Genetic |
SPT8 |
YLR055C |
Subunit of the SAGA transcriptional regulatory complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
5 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CLB5 |
YPR120C |
B-type cyclin involved in DNA replication during S phase |
genetic |
5 |
2 |
4 |
Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPL11B |
YGR085C |
Ribosomal 60S subunit protein L11B |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HPC2 |
YBR215W |
Subunit of the HIR complex |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
5 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
NUM1 |
YDR150W |
Protein required for nuclear migration |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPL13A |
YDL082W |
Ribosomal 60S subunit protein L13A |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MET16 |
YPR167C |
3'-phosphoadenylsulfate reductase |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DPB3 |
YBR278W |
Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification |
MFA2 |
YNL145W |
Mating pheromone a-factor |
physical |
4 |
2 |
4 |
Affinity Capture-RNA, Protein-RNA, Affinity Capture-RNA, Protein-RNA |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
physical |
4 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
4 |
2 |
4 |
Positive Genetic, Synthetic Growth Defect, Positive Genetic, Positive Genetic |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
FUM1 |
YPL262W |
Fumarase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
genetic |
4 |
4 |
3 |
Negative Genetic, Dosage Growth Defect, Positive Genetic, Synthetic Rescue |
HTA1 |
YDR225W |
Histone H2A |
genetic |
4 |
3 |
3 |
Positive Genetic, Positive Genetic, Synthetic Rescue, Dosage Growth Defect |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
4 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
RPL23A |
YBL087C |
Ribosomal 60S subunit protein L23A |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
CDC45 |
YLR103C |
DNA replication initiation factor |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PUF4 |
YGL014W |
Member of the PUF protein family |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
4 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
RPS7B |
YNL096C |
Protein component of the small (40S) ribosomal subunit |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RPS28A |
YOR167C |
Protein component of the small (40S) ribosomal subunit |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TAF8 |
YML114C |
TFIID subunit (65 kDa) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
4 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic, Positive Genetic |
RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
4 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PEX12 |
YMR026C |
C3HC4-type RING-finger peroxin and E3 ubiquitin ligase |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RAD53 |
YPL153C |
DNA damage response kinase |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Phenotypic Enhancement |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
3 |
3 |
3 |
Dosage Lethality, Negative Genetic, Synthetic Lethality |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Synthetic Lethality, Positive Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
3 |
3 |
3 |
Synthetic Growth Defect, Negative Genetic, Positive Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
3 |
2 |
3 |
Positive Genetic, Positive Genetic, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
3 |
2 |
3 |
Positive Genetic, Negative Genetic, Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
3 |
2 |
3 |
Negative Genetic, Positive Genetic, Positive Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic |
RPL43B |
YJR094W-A |
Ribosomal 60S subunit protein L43B |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic |
RPL4A |
YBR031W |
Ribosomal 60S subunit protein L4A |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
HAT2 |
YEL056W |
Subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA |
CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TCP1 |
YDR212W |
Alpha subunit of chaperonin-containing T-complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
CYM1 |
YDR430C |
Lysine-specific metalloprotease of the pitrilysin family |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
1 |
3 |
Positive Genetic, Positive Genetic, Positive Genetic |
DPH2 |
YKL191W |
Protein required for synthesis of diphthamide |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
3 |
3 |
2 |
Phenotypic Enhancement, Dosage Lethality, Positive Genetic |
HTB1 |
YDR224C |
Histone H2B |
genetic |
3 |
3 |
2 |
Positive Genetic, Synthetic Rescue, Dosage Growth Defect |
HHT2 |
YNL031C |
Histone H3 |
genetic |
3 |
3 |
2 |
Negative Genetic, Synthetic Rescue, Dosage Growth Defect |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Positive Genetic |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Positive Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Dosage Lethality |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
2 |
2 |
Negative Genetic, Positive Genetic, Positive Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
SLU7 |
YDR088C |
RNA splicing factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MTO1 |
YGL236C |
Mitochondrial protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
MDM12 |
YOL009C |
Mitochondrial outer membrane protein, ERMES complex subunit |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRS2 |
YOR334W |
Mitochondrial inner membrane Mg(2+) channel |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TYE7 |
YOR344C |
Serine-rich protein that contains a bHLH DNA binding motif |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MSC6 |
YOR354C |
Multicopy suppressor of HER2 involved in mitochondrial translation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SLD3 |
YGL113W |
Protein involved in the initiation of DNA replication |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
APL5 |
YPL195W |
Delta adaptin-like subunit of the clathrin associated protein complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FRQ1 |
YDR373W |
N-myristoylated calcium-binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
ATC1 |
YDR184C |
Nuclear protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
DPH5 |
YLR172C |
Methyltransferase required for synthesis of diphthamide |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YOX1 |
YML027W |
Homeobox transcriptional repressor |
genetic |
3 |
3 |
1 |
Positive Genetic, Synthetic Rescue, Dosage Growth Defect |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
3 |
2 |
1 |
Positive Genetic, Negative Genetic, Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
RPL41A |
YDL184C |
Ribosomal 60S subunit protein L41A |
physical |
2 |
2 |
2 |
Affinity Capture-RNA, Protein-RNA |
PGK1 |
YCR012W |
3-phosphoglycerate kinase |
physical |
2 |
2 |
2 |
Protein-RNA, Affinity Capture-RNA |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Growth Defect |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-RNA |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-RNA |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement |
RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ORC1 |
YML065W |
Largest subunit of the origin recognition complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
2 |
2 |
2 |
Positive Genetic, Synthetic Rescue |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Positive Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
HIF1 |
YLL022C |
Non-essential component of the HAT-B histone acetyltransferase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
EMI1 |
YDR512C |
Non-essential protein of unknown function |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAP123 |
YER110C |
Karyopherin beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RSC1 |
YGR056W |
Component of the RSC chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNF11 |
YDR073W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAD24 |
YER173W |
Checkpoint protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MSH2 |
YOL090W |
Protein that binds to DNA mismatches |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TSR2 |
YLR435W |
Protein with a potential role in pre-rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNT309 |
YPR101W |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SNX41 |
YDR425W |
Sorting nexin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UPS2 |
YLR168C |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TSR3 |
YOR006C |
Protein required for 20S pre-rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PRP3 |
YDR473C |
Splicing factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TAF4 |
YMR005W |
TFIID subunit (48 kDa) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ATP11 |
YNL315C |
Molecular chaperone |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
FCF1 |
YDR339C |
PINc domain endonuclease |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CRC1 |
YOR100C |
Mitochondrial inner membrane carnitine transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GDH1 |
YOR375C |
NADP(+)-dependent glutamate dehydrogenase |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
AIM14 |
YGL160W |
NADPH oxidase localized to the perinuclear ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FMT1 |
YBL013W |
Methionyl-tRNA formyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
RRS1 |
YOR294W |
Essential protein that binds ribosomal protein L11 |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
TMA16 |
YOR252W |
Protein of unknown function that associates with ribosomes |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
genetic |
2 |
2 |
1 |
Phenotypic Suppression, Dosage Growth Defect |
HHF2 |
YNL030W |
Histone H4 |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Growth Defect |
ACF4 |
YJR083C |
Protein of unknown function |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
ARL3 |
YPL051W |
ARF-like small GTPase of the RAS superfamily |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YJR120W |
YJR120W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RPS30B |
YOR182C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SNM1 |
YDR478W |
Ribonuclease MRP complex subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TOA1 |
YOR194C |
TFIIA large subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MDM38 |
YOL027C |
Membrane-associated mitochondrial ribosome receptor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
EMI2 |
YDR516C |
Hexokinase expressed during growth with low glucose levels |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRX1 |
YOL077C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
physical |
1 |
1 |
1 |
Two-hybrid |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
MTR3 |
YGR158C |
Exosome non-catalytic core component |
physical |
1 |
1 |
1 |
Two-hybrid |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
physical |
1 |
1 |
1 |
Two-hybrid |
PMT4 |
YJR143C |
Protein O-mannosyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
physical |
1 |
1 |
1 |
Two-hybrid |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
physical |
1 |
1 |
1 |
Two-hybrid |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDS24 |
YBR214W |
Protein involved in cell separation during budding |
physical |
1 |
1 |
1 |
Two-hybrid |
SIP1 |
YDR422C |
One of three alternate beta-subunits of the Snf1p kinase complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Two-hybrid |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Two-hybrid |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
STE11 |
YLR362W |
Signal transducing MEK kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SLM5 |
YCR024C |
Mitochondrial asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Two-hybrid |
MIG3 |
YER028C |
Transcriptional regulator |
physical |
1 |
1 |
1 |
Two-hybrid |
PKP1 |
YIL042C |
Mitochondrial protein kinase |
physical |
1 |
1 |
1 |
Two-hybrid |
UFO1 |
YML088W |
F-box receptor protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SIW14 |
YNL032W |
Inositol phosphatase involved in inositol pyrophosphate metabolism |
physical |
1 |
1 |
1 |
Two-hybrid |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
physical |
1 |
1 |
1 |
Two-hybrid |
YRB1 |
YDR002W |
Ran GTPase binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SMX3 |
YPR182W |
Core Sm protein Sm F |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
LSM8 |
YJR022W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
PMP1 |
YCR024C-A |
Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p |
physical |
1 |
1 |
1 |
Two-hybrid |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
physical |
1 |
1 |
1 |
Co-purification |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
physical |
1 |
1 |
1 |
Protein-RNA |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
URA7 |
YBL039C |
Major CTP synthase isozyme (see also URA8) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS11B |
YBR048W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS9B |
YBR189W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OM14 |
YBR230C |
Mitochondrial outer membrane receptor for cytosolic ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SHG1 |
YBR258C |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRH1 |
YDR033W |
Protein that localizes primarily to the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TPI1 |
YDR050C |
Triose phosphate isomerase, abundant glycolytic enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEX3 |
YDR329C |
Peroxisomal membrane protein (PMP) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS17B |
YDR447C |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YDR524C-B |
YDR524C-B |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PMP2 |
YEL017C-A |
Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SNU13 |
YEL026W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YER010C |
YER010C |
Bifunctional HMG aldolase/oxaloacetate decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SAH1 |
YER043C |
S-adenosyl-L-homocysteine hydrolase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS24A |
YER074W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL23B |
YER117W |
Ribosomal 60S subunit protein L23B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS26B |
YER131W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MIL1 |
YFL034W |
Predicted lipase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TUB2 |
YFL037W |
Beta-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC53 |
YFL045C |
Phosphomannomutase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SEC53 |
YFL045C |
Phosphomannomutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL1B |
YGL135W |
Ribosomal 60S subunit protein L1B |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YGR079W |
YGR079W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDH3 |
YGR192C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPC3 |
YGR243W |
Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL27A |
YHR010W |
Ribosomal 60S subunit protein L27A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
THR1 |
YHR025W |
Homoserine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS4B |
YHR203C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL2B |
YIL018W |
Ribosomal 60S subunit protein L2B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MMF1 |
YIL051C |
Mitochondrial protein required for transamination of isoleucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL047C-A |
YJL047C-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SIP4 |
YJL089W |
C6 zinc cluster transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TIM17 |
YJL143W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TDH2 |
YJR009C |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS5 |
YJR123W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YJR142W |
YJR142W |
8-oxo-dGTP diphosphatase of the Nudix hydrolase family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIR1 |
YKL164C |
O-glycosylated protein required for cell wall stability |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LST4 |
YKL176C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PDC1 |
YLR044C |
Major of three pyruvate decarboxylase isozymes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SEN2 |
YLR105C |
Subunit of the tRNA splicing endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YLR154C-G |
YLR154C-G |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS22B |
YLR367W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PHO84 |
YML123C |
High-affinity inorganic phosphate (Pi) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPL13B |
YMR142C |
Ribosomal 60S subunit protein L13B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL9B |
YNL067W |
Ribosomal 60S subunit protein L9B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL16B |
YNL069C |
Ribosomal 60S subunit protein L16B |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM7 |
YNL070W |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YNL190W |
YNL190W |
Hydrophilin essential in desiccation-rehydration process |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Positive Genetic |
MPA43 |
YNL249C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ORC5 |
YNL261W |
Subunit of the origin recognition complex (ORC) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOG2 |
YNR053C |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOS7 |
YOL019W |
Protein involved in secretion and cell wall organization |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SKM1 |
YOL113W |
Member of the PAK family of serine/threonine protein kinases |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SNX3 |
YOR357C |
Sorting nexin for late-Golgi enzymes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL5 |
YPL131W |
Ribosomal 60S subunit protein L5 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PXA1 |
YPL147W |
Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPL7B |
YPL198W |
Ribosomal 60S subunit protein L7B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO24 |
YPR036W-A |
Small (67 amino acids) protein involved in sporulation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TKL1 |
YPR074C |
Transketolase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NCA2 |
YPR155C |
Protein that regulates expression of Fo-F1 ATP synthase subunits |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
NMD4 |
YLR363C |
Protein that may be involved in nonsense-mediated mRNA decay |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STL1 |
YDR536W |
Glycerol proton symporter of the plasma membrane |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRB8 |
YCR081W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKA1 |
YKL023W |
SKI complex-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRI1 |
YIR008C |
Subunit of DNA primase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS4 |
YDR181C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS70 |
YJR126C |
Protein of unknown function involved in vacuolar protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS5 |
YOR213C |
Subunit of the SAS complex (Sas2p, Sas4p, Sas5p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEX1 |
YNL253W |
Protein involved in mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFD1 |
YJL179W |
Subunit of heterohexameric prefoldin |
genetic |
1 |
1 |
1 |
Positive Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS75 |
YNL246W |
NAP family histone chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YEF3 |
YLR249W |
Translation elongation factor 3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP4 |
YDR324C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP8 |
YBL018C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRP1 |
YDL167C |
Putative RNA binding protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP120 |
YKL057C |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET309 |
YLR067C |
Specific translational activator for the COX1 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEF1 |
YLR069C |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
MAK32 |
YCR019W |
Protein necessary for stability of L-A dsRNA-containing particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIE1 |
YGR250C |
RNA binding protein and negative regulator of START |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
NMD5 |
YJR132W |
Karyopherin |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Positive Genetic |
RNA14 |
YMR061W |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDA1 |
YGR245C |
Protein required for actin organization and passage through Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR020W |
YHR020W |
Prolyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRI2 |
YOL117W |
Subunit of the COP9 signalosome (CSN) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
YOR008C-A |
YOR008C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Dosage Rescue |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZAP1 |
YJL056C |
Zinc-regulated transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Dosage Lethality |
MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS1 |
YKR001C |
Dynamin-like GTPase required for vacuolar sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM30 |
YLR368W |
F-box component of an SCF ubiquitin protein ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM18 |
YOR297C |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
STN1 |
YDR082W |
Telomere end-binding and capping protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
MPE1 |
YKL059C |
Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGA1 |
YNL158W |
Essential component of GPI-mannosyltransferase II |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Positive Genetic |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YHL017W |
YHL017W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Positive Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
MET7 |
YOR241W |
Folylpolyglutamate synthetase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP6 |
YBR055C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS1 |
YDR113C |
Securin |
genetic |
1 |
1 |
1 |
Negative Genetic |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPP41 |
YDR464W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP40 |
YKL012W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP14 |
YKL082C |
Essential protein, constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR2 |
YKL186C |
mRNA transport regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT4 |
YLR305C |
Phosphatidylinositol-4-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP8 |
YOL144W |
Nucleolar protein required for 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOB1 |
YOR056C |
Protein involved in proteasomal and 40S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL3 |
YOR063W |
Ribosomal 60S subunit protein L3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTR10 |
YOR160W |
Nuclear import receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRS6 |
YOR370C |
Rab escort protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP4 |
YPL043W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP46 |
YPL151C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM44 |
YIL022W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB5 |
YDR079C-A |
Component of RNA polymerase II general transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX10 |
YDR265W |
Peroxisomal membrane E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL14B |
YHL001W |
Ribosomal 60S subunit protein L14B |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
REC104 |
YHR157W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDL2 |
YPL270W |
Mitochondrial inner membrane half-type ABC transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR041W |
YKR041W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKG1 |
YKR100C |
Transmembrane protein with a role in cell wall polymer composition |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL6A |
YML073C |
Ribosomal 60S subunit protein L6A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL067W-B |
YNL067W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL20B |
YOR312C |
Ribosomal 60S subunit protein L20B |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET20 |
YPL159C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19B |
YNL302C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG1 |
YOR064C |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAS3 |
YBL052C |
Histone acetyltransferase catalytic subunit of NuA3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE7 |
YDL159W |
Signal transducing MAP kinase kinase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NTC20 |
YBR188C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNQ2 |
YDR011W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPN1 |
YDR452W |
Dual endo- and exopolyphosphatase with a role in phosphate metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSA1 |
YOR066W |
Activator of G1-specific transcription factors MBF and SBF |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Positive Genetic |
SET1 |
YHR119W |
Histone methyltransferase, subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIB2 |
YGL023C |
Phosphatidylinositol 3-phosphate binding protein |
genetic |
1 |
1 |
1 |
Dosage Lethality |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
REX3 |
YLR107W |
RNA exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
STH1 |
YIL126W |
ATPase component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TEC1 |
YBR083W |
Transcription factor targeting filamentation genes and Ty1 expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
RNH70 |
YGR276C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
NHP6A |
YPR052C |
High-mobility group (HMG) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL29 |
YFR032C-A |
Ribosomal 60S subunit protein L29 |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUC1 |
YJL208C |
Major mitochondrial nuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
RMD5 |
YDR255C |
Component of GID Complex that confers ubiquitin ligase (U3) activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL17B |
YJL177W |
Ribosomal 60S subunit protein L17B |
genetic |
1 |
1 |
1 |
Positive Genetic |
YLR257W |
YLR257W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC2 |
YFR031C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SER1 |
YOR184W |
3-phosphoserine aminotransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALA1 |
YOR335C |
Cytoplasmic and mitochondrial alanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFT2 |
YDR385W |
Elongation factor 2 (EF-2), also encoded by EFT1 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CIA2 |
YHR122W |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GCD7 |
YLR291C |
Beta subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Two-hybrid |
GDI1 |
YER136W |
GDP dissociation inhibitor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BDF2 |
YDL070W |
Protein involved in transcription initiation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLY1 |
YEL046C |
Threonine aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HTB2 |
YBL002W |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENO2 |
YHR174W |
Enolase II, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADA2 |
YDR448W |
Transcription coactivator |
genetic |
1 |
1 |
1 |
Negative Genetic |
FBA1 |
YKL060C |
Fructose 1,6-bisphosphate aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
KAP114 |
YGL241W |
Karyopherin, responsible for nuclear import of specific proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
IES1 |
YFL013C |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPD1 |
YFL018C |
Dihydrolipoamide dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPM1 |
YKL152C |
Tetrameric phosphoglycerate mutase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CSI1 |
YMR025W |
Subunit of the Cop9 signalosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
EFB1 |
YAL003W |
Translation elongation factor 1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EFB1 |
YAL003W |
Translation elongation factor 1 beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRO1 |
YPL084W |
Cytoplasmic class E vacuolar protein sorting (VPS) factor |
physical |
1 |
1 |
1 |
Two-hybrid |
FUN30 |
YAL019W |
Snf2p family member with ATP-dependent chromatin remodeling activity |
physical |
1 |
1 |
1 |
Two-hybrid |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CMS1 |
YLR003C |
Putative subunit of the 90S preribosome processome complex |
physical |
1 |
1 |
1 |
Two-hybrid |
ATP2 |
YJR121W |
Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTB1 |
YDR224C |
Histone H2B |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KOG1 |
YHR186C |
Subunit of TORC1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CHK1 |
YBR274W |
Serine/threonine kinase and DNA damage checkpoint effector |
physical |
1 |
1 |
1 |
Two-hybrid |
CMK1 |
YFR014C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
AAC1 |
YMR056C |
Mitochondrial inner membrane ADP/ATP translocator |
physical |
1 |
1 |
1 |
Two-hybrid |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DYN2 |
YDR424C |
Cytoplasmic light chain dynein, microtubule motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DSS1 |
YMR287C |
3'-5' exoribonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
FHL1 |
YPR104C |
Regulator of ribosomal protein (RP) transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
INA1 |
YLR413W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHT1 |
YBR010W |
Histone H3 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LHS1 |
YKL073W |
Molecular chaperone of the endoplasmic reticulum lumen |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUT1 |
YBR252W |
Deoxyuridine triphosphate diphosphatase (dUTPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LOS1 |
YKL205W |
Nuclear pore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAP1 |
YPL170W |
Heme-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
IGO1 |
YNL157W |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
BNA5 |
YLR231C |
Kynureninase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DHR2 |
YKL078W |
Predominantly nucleolar DEAH-box ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HOF1 |
YMR032W |
F-BAR protein that regulates actin cytoskeleton organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IME4 |
YGL192W |
mRNA N6-adenosine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BAS1 |
YKR099W |
Myb-related transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISY1 |
YJR050W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMT2 |
YBR141C |
Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM4 |
YBR194W |
Protein proposed to be associated with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMT5 |
YIL096C |
Methyltransferase required for m3U2634 methylation of the 25S rRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC31 |
YOR257W |
Calcium-binding component of the spindle pole body (SPB) half-bridge |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCD1 |
YHR144C |
Deoxycytidine monophosphate (dCMP) deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAP1 |
YKR039W |
General amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
FCP1 |
YMR277W |
Carboxy-terminal domain (CTD) phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Positive Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
physical |
1 |
1 |
1 |
Two-hybrid |
GAD1 |
YMR250W |
Glutamate decarboxylase |
physical |
1 |
1 |
1 |
Two-hybrid |
GNT1 |
YOR320C |
N-acetylglucosaminyltransferase |
physical |
1 |
1 |
1 |
Two-hybrid |
DPH6 |
YLR143W |
Diphthamide synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DPH6 |
YLR143W |
Diphthamide synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Positive Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
DID2 |
YKR035W-A |
Class E protein of the vacuolar protein-sorting (Vps) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG10 |
YLL042C |
Conserved E2-like conjugating enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFT1 |
YOR133W |
Elongation factor 2 (EF-2), also encoded by EFT2 |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ASN2 |
YGR124W |
Asparagine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRG1 |
YHR209W |
S-AdoMet-dependent methyltransferase involved in lipid homeostasis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARO8 |
YGL202W |
Aromatic aminotransferase I |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ATP18 |
YML081C-A |
Subunit of the mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ9 |
YLR201C |
Protein required for ubiquinone biosynthesis and respiratory growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IAI11 |
YBL059W |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BAR1 |
YIL015W |
Aspartyl protease secreted to periplasmic space of mating type a cell |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ALD6 |
YPL061W |
Cytosolic aldehyde dehydrogenase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSH1 |
YBR161W |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IRC19 |
YLL033W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GEM1 |
YAL048C |
Outer mitochondrial membrane GTPase, subunit of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
1 |
1 |
1 |
Positive Genetic |
LDB7 |
YBL006C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CMK2 |
YOL016C |
Calmodulin-dependent protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICS2 |
YBR157C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST2 |
YLR318W |
Reverse transcriptase subunit of the telomerase holoenzyme |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
JJJ3 |
YJR097W |
Iron-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXT2 |
YMR011W |
High-affinity glucose transporter of the major facilitator superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERS1 |
YCR075C |
Protein involved in cystine transport |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CGR1 |
YGL029W |
Protein involved in nucleolar integrity and processing of pre-rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
DSE2 |
YHR143W |
Daughter cell-specific secreted protein with similarity to glucanases |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CMC1 |
YKL137W |
Copper-binding protein of the mitochondrial intermembrane space |
genetic |
1 |
1 |
1 |
Negative Genetic |
IGO2 |
YHR132W-A |
Protein required for initiation of G0 program |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
FMC1 |
YIL098C |
Mitochondrial matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLD1 |
YPR109W |
Component of Dsc E3 ligase complex in Golgi and endosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Positive Genetic |
ITR2 |
YOL103W |
Myo-inositol transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
EFM2 |
YBR271W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL1 |
YIR027C |
Allantoinase |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADF1 |
YCL058W-A |
Transcriptional repressor encoded by the FYV5 antisense strand |
genetic |
1 |
1 |
1 |
Positive Genetic |