Standard name Systematic name Name description Description
DGK1 YOR311C Diacylglycerol kinase Diacylglycerol kinase; localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain
Visualize the interactome of DGK1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.473 0.417 0.462
ER 0.182 0.479 0.352
Mito 0.426 NaN 0.223
Vac/Vac Memb 0.101 0.177 0.073

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DGK1 3 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2516 (DAG kinase (1-16:0, 2-18:1), ER membrane), r_2513 (DAG kinase (1-16:1, 2-16:1), ER membrane), r_2519 (DAG kinase (1-18:1, 2-18:1), ER membrane), r_2512 (DAG kinase (1-16:0, 2-16:1), ER membrane), r_2518 (DAG kinase (1-18:0, 2-18:1), ER membrane), r_2515 (DAG kinase (1-18:1, 2-16:1), ER membrane), r_2517 (DAG kinase (1-16:1, 2-18:1), ER membrane), r_2514 (DAG kinase (1-18:0, 2-16:1), ER membrane)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 9 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
DGA1 YOR245C Diacylglycerol acyltransferase genetic 7 3 5 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 7 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPT23 YKL020C ER membrane protein involved in regulation of OLE1 transcription genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 6 2 4 Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic
CKI1 YLR133W Choline kinase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR3 YMR052W Protein of unknown function genetic 6 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 6 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 5 4 5 Dosage Rescue, Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 5 3 4 Dosage Rescue, Positive Genetic, Phenotypic Suppression, Phenotypic Suppression, Positive Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PCT1 YGR202C Cholinephosphate cytidylyltransferase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG8 YOR067C Glucosyl transferase genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERP1 YAR002C-A Member of the p24 family involved in ER to Golgi transport genetic 4 2 3 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEY1 YOR165W Dynamin-like GTPase that mediates homotypic ER fusion genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NIP100 YPL174C Large subunit of the dynactin complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YJU3 YKL094W Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FAR7 YFR008W Protein involved in recovery from pheromone-induced cell cycle arrest genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
LDB18 YLL049W Component of the dynactin complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 3 1 3 Positive Genetic, Positive Genetic, Positive Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Rescue
RTN1 YDR233C Reticulon protein genetic 3 2 2 Positive Genetic, Positive Genetic, Dosage Growth Defect
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 3 2 2 Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression
BRE1 YDL074C E3 ubiquitin ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COX10 YPL172C Heme A:farnesyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NUM1 YDR150W Protein required for nuclear migration genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMP3 YDR276C Small plasma membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
OMS1 YDR316W Protein integral to the mitochondrial membrane genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HNM1 YGL077C Plasma membrane transporter for choline, ethanolamine, and carnitine genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ECT1 YGR007W Ethanolamine-phosphate cytidylyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
GSH1 YJL101C Gamma glutamylcysteine synthetase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
JNM1 YMR294W Component of the yeast dynactin complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DYN3 YMR299C Dynein light intermediate chain (LIC) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
PHO80 YOL001W Cyclin genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PPG1 YNR032W Serine protein phosphatase involved in formation of FAR complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 2 2 Negative Genetic, Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 2 2 Positive Genetic, Negative Genetic
COX5A YNL052W Subunit Va of cytochrome c oxidase genetic 2 1 2 Negative Genetic, Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 2 1 2 Positive Genetic, Positive Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 2 1 2 Negative Genetic, Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 2 1 2 Negative Genetic, Negative Genetic
COX8 YLR395C Subunit VIII of cytochrome c oxidase (Complex IV) genetic 2 1 2 Negative Genetic, Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 2 1 2 Negative Genetic, Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 2 1 2 Negative Genetic, Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 2 1 2 Negative Genetic, Negative Genetic
PRS4 YBL068W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP genetic 2 1 2 Negative Genetic, Negative Genetic
FMT1 YBL013W Methionyl-tRNA formyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 2 1 2 Negative Genetic, Negative Genetic
FAT1 YBR041W Very long chain fatty acyl-CoA synthetase and fatty acid transporter genetic 2 1 2 Negative Genetic, Negative Genetic
MIS1 YBR084W Mitochondrial C1-tetrahydrofolate synthase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD16 YBR114W Nucleotide excision repair (NER) protein genetic 2 1 2 Positive Genetic, Positive Genetic
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 2 1 2 Negative Genetic, Negative Genetic
YCL042W YCL042W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
HEM25 YDL119C Mitochondrial glycine transporter genetic 2 1 2 Negative Genetic, Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
YDR444W YDR444W Putative hydrolase acting on ester bonds genetic 2 1 2 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 2 1 2 Negative Genetic, Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 2 Positive Genetic, Positive Genetic
MON1 YGL124C Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 2 1 2 Negative Genetic, Negative Genetic
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 2 1 2 Negative Genetic, Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RIE1 YGR250C RNA binding protein and negative regulator of START genetic 2 1 2 Negative Genetic, Negative Genetic
YHL008C YHL008C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
HAP4 YKL109W Transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 2 1 2 Negative Genetic, Negative Genetic
DID2 YKR035W-A Class E protein of the vacuolar protein-sorting (Vps) pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 2 1 2 Negative Genetic, Negative Genetic
YPT7 YML001W Rab family GTPase genetic 2 1 2 Negative Genetic, Negative Genetic
PDL32 YMR087W Putative ADP-ribose-1''-monophosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 2 1 2 Negative Genetic, Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 2 1 2 Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane genetic 2 1 2 Negative Genetic, Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 2 1 2 Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 1 2 Negative Genetic, Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 2 1 2 Positive Genetic, Positive Genetic
AIM36 YMR157C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 2 2 1 Positive Genetic, Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 2 2 1 Positive Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 2 1 1 Negative Genetic, Negative Genetic
CKB2 YOR039W Beta' regulatory subunit of casein kinase 2 (CK2) genetic 2 1 1 Positive Genetic, Positive Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Negative Genetic, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 2 1 1 Negative Genetic, Negative Genetic
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 2 1 1 Positive Genetic, Positive Genetic
BIO2 YGR286C Biotin synthase genetic 2 1 1 Negative Genetic, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 2 1 1 Positive Genetic, Positive Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 2 1 1 Positive Genetic, Positive Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 2 1 1 Negative Genetic, Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase genetic 2 1 1 Negative Genetic, Negative Genetic
YET3 YDL072C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase genetic 2 1 1 Positive Genetic, Positive Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 2 1 1 Negative Genetic, Negative Genetic
TRM3 YDL112W 2'-O-ribose methyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 1 Positive Genetic, Positive Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 1 Positive Genetic, Positive Genetic
YDR124W YDR124W Mitochondrial protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 2 1 1 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
HAP2 YGL237C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 2 1 1 Negative Genetic, Negative Genetic
POX1 YGL205W Fatty-acyl coenzyme A oxidase genetic 2 1 1 Negative Genetic, Negative Genetic
PEX31 YGR004W Peroxisomal integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
SPO12 YHR152W Nucleolar protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 2 1 1 Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Positive Genetic, Positive Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 2 1 1 Negative Genetic, Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 2 1 1 Negative Genetic, Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
KIP2 YPL155C Kinesin-related motor protein involved in mitotic spindle positioning genetic 2 1 1 Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Negative Genetic, Negative Genetic
THP3 YPR045C Protein that may have a role in transcription elongation genetic 2 1 1 Negative Genetic, Negative Genetic
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 1 1 Negative Genetic, Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 2 1 1 Negative Genetic, Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
SEC65 YML105C Subunit of the signal recognition particle (SRP) genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 quantitative reverse transcription polymerase chain reaction evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CKA1 YIL035C Alpha catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Biochemical Activity
CKB1 YGL019W Beta regulatory subunit of casein kinase 2 (CK2) genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
CFT1 YDR301W RNA-binding subunit of the mRNA cleavage and polyadenylation factor genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Positive Genetic
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Positive Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Positive Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Positive Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization genetic 1 1 1 Negative Genetic
ARE2 YNR019W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Phenotypic Suppression
ARE1 YCR048W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Phenotypic Suppression
ADE17 YMR120C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Positive Genetic
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II genetic 1 1 1 Negative Genetic
CTR1 YPR124W High-affinity copper transporter of plasma membrane physical 1 1 1 PCA
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
CUP2 YGL166W Copper-binding transcription factor genetic 1 1 1 Negative Genetic
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins genetic 1 1 1 Positive Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
BUD6 YLR319C Actin- and formin-interacting protein genetic 1 1 1 Negative Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
CFD1 YIL003W Highly conserved iron-sulfur cluster binding protein genetic 1 1 1 Positive Genetic
COI1 YDR381C-A Mitochondrial assembly factor genetic 1 1 1 Positive Genetic
AHK1 YDL073W Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway genetic 1 1 1 Negative Genetic
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
CMR3 YPR013C Putative zinc finger protein genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Positive Genetic
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Negative Genetic
COX12 YLR038C Subunit VIb of cytochrome c oxidase genetic 1 1 1 Negative Genetic
CCC2 YDR270W Cu(+2)-transporting P-type ATPase genetic 1 1 1 Positive Genetic
CMI7 YIL002W-A Putative mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
CMC1 YKL137W Copper-binding protein of the mitochondrial intermembrane space genetic 1 1 1 Negative Genetic
COS6 YGR295C Endosomal protein involved in turnover of plasma membrane proteins genetic 1 1 1 Negative Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 1 1 1 PCA
SEC22 YLR268W R-SNARE protein physical 1 1 1 PCA
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER physical 1 1 1 Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Dosage Rescue
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
MGA2 YIR033W ER membrane protein involved in regulation of OLE1 transcription genetic 1 1 1 Phenotypic Enhancement
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Phenotypic Suppression
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein genetic 1 1 1 Synthetic Lethality
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Negative Genetic
TIM11 YDR322C-A Subunit e of mitochondrial F1F0-ATPase genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Negative Genetic
ERG11 YHR007C Lanosterol 14-alpha-demethylase genetic 1 1 1 Negative Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
PGA3 YML125C Putative cytochrome b5 reductase, localized to the plasma membrane genetic 1 1 1 Negative Genetic
NAT4 YMR069W N alpha-acetyl-transferase genetic 1 1 1 Negative Genetic
RBG1 YAL036C Member of the DRG family of GTP-binding proteins genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
FUN14 YAL008W Integral mitochondrial outer membrane (MOM) protein genetic 1 1 1 Negative Genetic
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Positive Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
YBR137W YBR137W Protein with a role in ER delivery of tail-anchored membrane proteins genetic 1 1 1 Negative Genetic
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Positive Genetic
PYC2 YBR218C Pyruvate carboxylase isoform genetic 1 1 1 Positive Genetic
MSH6 YDR097C Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
MSC2 YDR205W Endoplasmic reticulum zinc transporter genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Positive Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Positive Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 1 1 1 Negative Genetic
YGR210C YGR210C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Positive Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Negative Genetic
IMP21 YIL154C Transcriptional activator involved in maintenance of ion homeostasis genetic 1 1 1 Negative Genetic
PHO86 YJL117W Endoplasmic reticulum (ER) resident protein genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 1 1 1 Negative Genetic
SAM37 YMR060C Component of the Sorting and Assembly Machinery (SAM) complex genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
SCW10 YMR305C Cell wall protein with similarity to glucanases genetic 1 1 1 Negative Genetic
SOL1 YNR034W Protein with a possible role in tRNA export genetic 1 1 1 Negative Genetic
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Negative Genetic
YOR111W YOR111W Putative protein of unknown function genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
ORM1 YGR038W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Synthetic Rescue
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Dosage Rescue
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
LDH1 YBR204C Serine hydrolase genetic 1 1 1 Negative Genetic
SEI1 YLR404W Seipin involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Positive Genetic
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Positive Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Positive Genetic
HEM13 YDR044W Coproporphyrinogen III oxidase genetic 1 1 1 Positive Genetic
NTF2 YER009W Nuclear envelope protein genetic 1 1 1 Positive Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Positive Genetic
SUA5 YGL169W Protein involved in threonylcarbamoyl adenosine biosynthesis genetic 1 1 1 Positive Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Positive Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
RRN5 YLR141W Protein involved in transcription of rDNA by RNA polymerase I genetic 1 1 1 Positive Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p genetic 1 1 1 Positive Genetic
RRP5 YMR229C RNA binding protein involved in synthesis of 18S and 5.8S rRNAs genetic 1 1 1 Positive Genetic
RRN9 YMR270C Protein involved in promoting high level transcription of rDNA genetic 1 1 1 Positive Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
ESF2 YNR054C Essential nucleolar protein involved in pre-18S rRNA processing genetic 1 1 1 Positive Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Positive Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Positive Genetic
FLO9 YAL063C Lectin-like protein with similarity to Flo1p genetic 1 1 1 Positive Genetic
LDB7 YBL006C Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Positive Genetic
YBR285W YBR285W Putative protein of unknown function genetic 1 1 1 Positive Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
MFG1 YDL233W Regulator of filamentous growth genetic 1 1 1 Positive Genetic
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site genetic 1 1 1 Positive Genetic
GRX3 YDR098C Glutathione-dependent oxidoreductase genetic 1 1 1 Positive Genetic
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit genetic 1 1 1 Positive Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
GRH1 YDR517W Acetylated cis-Golgi protein, homolog of human GRASP65 genetic 1 1 1 Positive Genetic
SPS2 YDR522C Protein expressed during sporulation genetic 1 1 1 Positive Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Positive Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Positive Genetic
NDT80 YHR124W Meiosis-specific transcription factor genetic 1 1 1 Positive Genetic
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 1 1 1 Positive Genetic
PRM10 YJL108C Pheromone-regulated protein genetic 1 1 1 Positive Genetic
SPO75 YLL005C Meiosis-specific protein of unknown function genetic 1 1 1 Positive Genetic
LMO1 YLL007C Homolog of mammalian ELMO (Engulfment and celL MOtility) genetic 1 1 1 Positive Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Positive Genetic
SRL2 YLR082C Protein of unknown function genetic 1 1 1 Positive Genetic
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p genetic 1 1 1 Positive Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Positive Genetic
MIH1 YMR036C Protein tyrosine phosphatase genetic 1 1 1 Positive Genetic
ECM5 YMR176W Subunit of the Snt2C complex genetic 1 1 1 Positive Genetic
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
YNR061C YNR061C Protein of unknown function genetic 1 1 1 Positive Genetic
THI20 YOL055C Trifunctional enzyme of thiamine biosynthesis, degradation and salvage genetic 1 1 1 Positive Genetic
YNG1 YOR064C Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Positive Genetic
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
STM1 YLR150W Protein required for optimal translation under nutrient stress genetic 1 1 1 Positive Genetic
MSS1 YMR023C Mitochondrial protein genetic 1 1 1 Positive Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
PRP6 YBR055C Splicing factor genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
SEC3 YER008C Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 1 1 1 Negative Genetic
UTP7 YER082C Nucleolar protein genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 1 1 1 Negative Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 1 1 1 Negative Genetic
GCD2 YGR083C Delta subunit of the translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
IPI1 YHR085W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
SEC11 YIR022W 18kDa catalytic subunit of the Signal Peptidase Complex (SPC) genetic 1 1 1 Negative Genetic
OST1 YJL002C Alpha subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
HSP60 YLR259C Tetradecameric mitochondrial chaperonin genetic 1 1 1 Negative Genetic
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
PRP39 YML046W U1 snRNP protein involved in splicing genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
TAH18 YPR048W Conserved NAPDH-dependent diflavin reductase genetic 1 1 1 Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 1 1 1 Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 1 1 1 Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
TAD3 YLR316C Subunit of tRNA-specific adenosine-34 deaminase genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
FIG1 YBR040W Integral membrane protein required for efficient mating genetic 1 1 1 Negative Genetic
MRPS9 YBR146W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Negative Genetic
RPL21A YBR191W Ribosomal 60S subunit protein L21A genetic 1 1 1 Negative Genetic
PAU24 YBR301W Cell wall mannoprotein genetic 1 1 1 Negative Genetic
YCL049C YCL049C Protein of unknown function genetic 1 1 1 Negative Genetic
PTC6 YCR079W Mitochondrial type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
EMA35 YCR100C Protein involved in protein sorting genetic 1 1 1 Negative Genetic
PMT5 YDL093W Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
TVP23 YDR084C Integral membrane protein genetic 1 1 1 Negative Genetic
MRPL35 YDR322W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPS8B YER102W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YFH7 YFR007W Putative kinase with similarity to the PRK/URK/PANK kinase subfamily genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
SHE10 YGL228W Protein involved in outer spore wall assembly genetic 1 1 1 Negative Genetic
GTO1 YGR154C Omega-class glutathione transferase genetic 1 1 1 Negative Genetic
YGR273C YGR273C Putative protein of unknown function genetic 1 1 1 Negative Genetic
TDA11 YHR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MTG2 YHR168W Putative GTPase genetic 1 1 1 Negative Genetic
SMN1 YHR202W Putative AMP hydrolase genetic 1 1 1 Negative Genetic
SDL1 YIL167W Blocked reading frame otherwise encoding L-serine dehydratase genetic 1 1 1 Negative Genetic
MET28 YIR017C bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Negative Genetic
MET5 YJR137C Sulfite reductase beta subunit genetic 1 1 1 Negative Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
QRI5 YLR204W Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
GRX8 YLR364W Glutaredoxin that employs a dithiol mechanism of catalysis genetic 1 1 1 Negative Genetic
EIS1 YMR031C Component of the eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
TVP18 YMR071C Integral membrane protein genetic 1 1 1 Negative Genetic
SDD2 YMR074C Protein with homology to human PDCD5 genetic 1 1 1 Negative Genetic
SRT1 YMR101C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Negative Genetic
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
DMA2 YNL116W Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Negative Genetic
LAG2 YOL025W Protein that negatively regulates the SCF E3-ubiquitin ligase genetic 1 1 1 Negative Genetic
SDD3 YOL098C Putative metalloprotease genetic 1 1 1 Negative Genetic
YOL131W YOL131W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCO2 YBR024W Protein anchored to mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MGR1 YCL044C Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
SYP1 YCR030C Negative regulator of WASP-Arp23 complex genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Negative Genetic
RDS1 YCR106W Putative zinc cluster transcription factor genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 1 1 1 Negative Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
NTH1 YDR001C Neutral trehalase, degrades trehalose genetic 1 1 1 Negative Genetic
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
UBC13 YDR092W E2 ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
YER084W YER084W Protein of unknown function genetic 1 1 1 Negative Genetic
YCK3 YER123W Palmitoylated vacuolar membrane-localized casein kinase I isoform genetic 1 1 1 Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
SUC2 YIL162W Invertase genetic 1 1 1 Negative Genetic
SGN1 YIR001C Cytoplasmic RNA-binding protein genetic 1 1 1 Negative Genetic
SMT1 YJL147C Translational repressor of the mitochondrial ATP6/8 mRNA genetic 1 1 1 Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
MAC1 YMR021C Copper-sensing transcription factor genetic 1 1 1 Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
MSS18 YPR134W Nuclear encoded protein needed for splicing of mitochondrial intron genetic 1 1 1 Negative Genetic
VPS4 YPR173C AAA-ATPase involved in multivesicular body (MVB) protein sorting genetic 1 1 1 Negative Genetic
USV1 YPL230W Putative transcription factor containing a C2H2 zinc finger genetic 1 1 1 Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Positive Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
YJL118W YJL118W Protein of unknown function genetic 1 1 1 Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Synthetic Rescue
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
RTN2 YDL204W Reticulon protein genetic 1 1 1 Dosage Growth Defect
YOP1 YPR028W Reticulon-interacting protein genetic 1 1 1 Dosage Growth Defect