| CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
3 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
| RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
2 |
2 |
2 |
Dosage Rescue, Negative Genetic |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Affinity Capture-Western |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
| STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SIR3 |
YLR442C |
Silencing protein |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| SIR4 |
YDR227W |
SIR protein involved in assembly of silent chromatin domains |
regulation |
1 |
1 |
1 |
RNA-sequencing evidence |
| ADA2 |
YDR448W |
Transcription coactivator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MCM1 |
YMR043W |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| PUT3 |
YKL015W |
Transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
regulation |
1 |
1 |
1 |
northern blot evidence |
| MATALPHA2 |
YCR039C |
Homeobox-domain protein |
regulation |
1 |
1 |
1 |
beta-galactosidase reporter gene assay evidence |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAK16 |
YAL025C |
Essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM5 |
YER146W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GCN3 |
YKR026C |
Alpha subunit of translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSM4 |
YER112W |
Lsm (Like Sm) protein |
physical |
1 |
1 |
1 |
Two-hybrid |
| MAS1 |
YLR163C |
Beta subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA3 |
YPR179C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD1 |
YPL022W |
Single-stranded DNA endonuclease (with Rad10p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GET3 |
YDL100C |
Guanine nucleotide exchange factor for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FMN1 |
YDR236C |
Riboflavin kinase, produces riboflavin monophosphate (FMN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFL1 |
YOR140W |
Transcriptional repressor and activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSC1 |
YJR045C |
Hsp70 family ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
physical |
1 |
1 |
1 |
PCA |
| YGL081W |
YGL081W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
PCA |
| YGR050C |
YGR050C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPK3 |
YBR028C |
AGC kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC17 |
YCL063W |
Phosphoprotein involved in vacuole inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR391C |
YDR391C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOR1 |
YGR281W |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ULA1 |
YPL003W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL071C |
YPL071C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| MOB1 |
YIL106W |
Component of the mitotic exit network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PPN1 |
YDR452W |
Dual endo- and exopolyphosphatase with a role in phosphate metabolism |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RGI2 |
YIL057C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAD1 |
YFR005C |
Conserved zinc-finger domain protein involved in pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MXR2 |
YCL033C |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
PCA |
| OXR1 |
YPL196W |
Protein involved in regulation of vacuolar V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLP1 |
YOR154W |
Glycosylated integral ER membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
