NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
4 |
2 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality, Synthetic Lethality |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CNE1 |
YAL058W |
Calnexin |
genetic |
3 |
2 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
3 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
3 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
3 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
GET4 |
YOR164C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
GCR2 |
YNL199C |
Transcriptional activator of genes involved in glycolysis |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
MDY2 |
YOL111C |
Protein involved in inserting tail-anchored proteins into ER membranes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
PHO80 |
YOL001W |
Cyclin |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
OST5 |
YGL226C-A |
Zeta subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
BUG1 |
YDL099W |
Cis-golgi localized protein involved in ER to Golgi transport |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
EMP65 |
YER140W |
Integral membrane protein of the ER |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
EMP65 |
YER140W |
Integral membrane protein of the ER |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SPT4 |
YGR063C |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
SUM1 |
YDR310C |
Transcriptional repressor that regulates middle-sporulation genes |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
YHR078W |
YHR078W |
High osmolarity-regulated gene of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
VPH2 |
YKL119C |
Integral membrane protein required for V-ATPase function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VMA11 |
YPL234C |
Vacuolar ATPase V0 domain subunit c' |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MMS21 |
YEL019C |
Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIS3 |
YOR202W |
Imidazoleglycerol-phosphate dehydratase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
OST1 |
YJL002C |
Alpha subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MNL1 |
YHR204W |
Alpha-1,2-specific exomannosidase of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
INA1 |
YLR413W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET191 |
YJR034W |
Protein required for assembly of cytochrome c oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KEG1 |
YFR042W |
Integral membrane protein of the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS0B |
YLR048W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRY2 |
YKR013W |
Sterol binding protein involved in the export of acetylated sterols |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL2 |
YIR029W |
Allantoicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YCS4 |
YLR272C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA2 |
YBR127C |
Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO1 |
YNL012W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI21 |
YPL258C |
Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |