Standard name Systematic name Name description Description
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways Transmembrane osmosensor for filamentous growth and HOG pathways; involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol (HOG) response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p
Visualize the interactome of SHO1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 20

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.225 0.216 0.233
Cytoplasm 0.346 0.518 0.418
ER 0.237 0.266 0.220
Endosome 0.058 NaN 0.053
Peroxisome 0.075 0.072 NaN
Vac/Vac Memb 0.183 NaN NaN
Bud NaN 0.058 0.148
Mito NaN NaN 0.082

GFP localization & abundance

GFP localization GFP abundance
bud neck, cytoplasm, cell periphery 2330

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SHO1 0 0 0 5 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway physical 10 4 9 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, PCA, Reconstituted Complex, Two-hybrid, Two-hybrid
SSK1 YLR006C Cytoplasmic phosphorelay intermediate osmosensor and regulator genetic 7 2 7 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect
STE11 YLR362W Signal transducing MEK kinase physical 7 4 4 Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, PCA, Two-hybrid
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 6 3 6 Two-hybrid, Affinity Capture-Western, PCA, PCA, Affinity Capture-Western, Affinity Capture-Western
MSB2 YGR014W Mucin family member involved in various signaling pathways genetic 6 3 5 Phenotypic Suppression, Phenotypic Suppression, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
MSB2 YGR014W Mucin family member involved in various signaling pathways physical 6 2 5 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FUS1 YCL027W Membrane protein localized to the shmoo tip physical 5 2 3 Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel physical 5 3 1 Affinity Capture-Western, Affinity Capture-Western, PCA, PCA, Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways physical 4 3 3 Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Two-hybrid
LAS17 YOR181W Actin assembly factor physical 4 2 3 Protein-peptide, Two-hybrid, Two-hybrid, Two-hybrid
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p physical 4 2 3 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BIK1 YCL029C Microtubule-associated protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation genetic 3 2 3 Phenotypic Enhancement, Phenotypic Suppression, Phenotypic Suppression
AHK1 YDL073W Scaffold protein in the HKR1 sub-branch of the Hog1p-signaling pathway physical 3 2 3 Two-hybrid, Two-hybrid, Affinity Capture-Western
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
INN1 YNL152W Essential protein that associates with contractile actomyosin ring physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring physical 3 3 2 Two-hybrid, PCA, Reconstituted Complex
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KAP95 YLR347C Karyopherin beta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CYC2 YOR037W Mitochondrial peripheral inner membrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GLY1 YEL046C Threonine aldolase physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
YER134C YER134C Magnesium-dependent acid phosphatase physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
LYS21 YDL131W Homocitrate synthase isozyme physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
ENT4 YLL038C Protein of unknown function physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
PUF2 YPR042C PUF family mRNA-binding protein physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
DIA1 YMR316W Protein of unknown function physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
ENA2 YDR039C P-type ATPase sodium pump physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
PMP3 YDR276C Small plasma membrane protein physical 3 3 1 Affinity Capture-Western, Two-hybrid, PCA
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 2 2 2 Synthetic Lethality, Phenotypic Suppression
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 2 2 2 Biochemical Activity, Co-localization
CHS3 YBR023C Chitin synthase III physical 2 2 2 PCA, Two-hybrid
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 2 2 2 Two-hybrid, Affinity Capture-Western
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 2 2 2 Phenotypic Enhancement, Synthetic Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 2 2 Negative Genetic, Dosage Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 2 2 2 Negative Genetic, Phenotypic Suppression
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 1 2 Negative Genetic, Negative Genetic
KIN2 YLR096W S/T protein kinase physical 2 1 2 Two-hybrid, Two-hybrid
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 2 Negative Genetic, Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 2 1 2 Negative Genetic, Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 2 1 2 Negative Genetic, Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 2 1 2 Negative Genetic, Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway physical 2 1 2 Affinity Capture-Western, Affinity Capture-Western
UTP7 YER082C Nucleolar protein physical 2 1 2 Two-hybrid, Two-hybrid
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 2 Negative Genetic, Negative Genetic
YOR1 YGR281W Plasma membrane ATP-binding cassette (ABC) transporter genetic 2 1 2 Negative Genetic, Negative Genetic
SLP1 YOR154W Glycosylated integral ER membrane protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 2 1 2 Negative Genetic, Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis physical 2 1 2 PCA, PCA
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors genetic 2 1 2 Negative Genetic, Negative Genetic
PYP1 YNL010W Sugar alcohol phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
CRS5 YOR031W Copper-binding metallothionein genetic 2 1 2 Negative Genetic, Negative Genetic
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 2 2 1 Two-hybrid, PCA
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 2 2 1 Two-hybrid, PCA
PGK1 YCR012W 3-phosphoglycerate kinase physical 2 2 1 Two-hybrid, PCA
GLN1 YPR035W Glutamine synthetase (GS) physical 2 2 1 Two-hybrid, PCA
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 2 2 1 Two-hybrid, PCA
HSP150 YJL159W O-mannosylated heat shock protein physical 2 2 1 Affinity Capture-Western, Two-hybrid
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator physical 2 2 1 Affinity Capture-Western, Two-hybrid
CDC19 YAL038W Pyruvate kinase physical 2 2 1 Two-hybrid, PCA
SIZ1 YDR409W SUMO E3 ligase physical 2 2 1 Affinity Capture-Western, Two-hybrid
TOR2 YKL203C PIK-related protein kinase and rapamycin target physical 2 2 1 Affinity Capture-Western, Two-hybrid
TPM2 YIL138C Minor isoform of tropomyosin physical 2 2 1 Two-hybrid, PCA
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 2 2 1 Two-hybrid, PCA
CWP2 YKL096W-A Covalently linked cell wall mannoprotein physical 2 2 1 Two-hybrid, PCA
MSB1 YOR188W Protein of unknown function physical 2 2 1 PCA, Reconstituted Complex
ENA5 YDR038C Protein with similarity to P-type ATPase sodium pumps physical 2 2 1 Two-hybrid, PCA
DCW1 YKL046C Putative mannosidase physical 2 2 1 Two-hybrid, PCA
FLO5 YHR211W Lectin-like cell wall protein (flocculin) involved in flocculation physical 2 2 1 Affinity Capture-Western, Two-hybrid
DAN4 YJR151C Cell wall mannoprotein physical 2 2 1 Affinity Capture-Western, Two-hybrid
FLO1 YAR050W Lectin-like protein involved in flocculation physical 2 2 1 Affinity Capture-Western, Two-hybrid
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 2 2 1 Synthetic Lethality, Synthetic Rescue
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 2 1 1 Negative Genetic, Negative Genetic
BUD8 YLR353W Protein involved in bud-site selection physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 1 Negative Genetic, Negative Genetic
PGS1 YCL004W Phosphatidylglycerolphosphate synthase genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
APQ12 YIL040W Nuclear envelope/ER integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TEC1 YBR083W Transcription factor targeting filamentation genes and Ty1 expression regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
STP1 YDR463W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family regulation 1 1 1 DNA to cDNA expression microarray evidence
MBP1 YDL056W Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
AME1 YBR211C Essential kinetochore protein associated with microtubules and SPBs genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase physical 1 1 1 Affinity Capture-Western
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Phenotypic Suppression
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
RRP7 YCL031C Essential protein involved in rRNA processing and ribosome biogenesis physical 1 1 1 Two-hybrid
MES1 YGR264C Methionyl-tRNA synthetase genetic 1 1 1 Negative Genetic
BMH1 YER177W 14-3-3 protein, major isoform genetic 1 1 1 Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
BOI2 YER114C Protein involved in polar growth physical 1 1 1 Two-hybrid
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Phenotypic Suppression
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
ATP11 YNL315C Molecular chaperone physical 1 1 1 Two-hybrid
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CDC16 YKL022C Subunit of the anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
MCM6 YGL201C Protein involved in DNA replication physical 1 1 1 Two-hybrid
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Two-hybrid
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 1 1 1 Two-hybrid
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 PCA
AVT4 YNL101W Vacuolar transporter physical 1 1 1 PCA
BSP1 YPR171W Adapter that links synaptojanins to the cortical actin cytoskeleton physical 1 1 1 Two-hybrid
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Two-hybrid
FUN19 YAL034C Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Growth Defect
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 1 1 1 Negative Genetic
ADR1 YDR216W Carbon source-responsive zinc-finger transcription factor physical 1 1 1 Two-hybrid
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 1 1 1 Positive Genetic
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
KDX1 YKL161C Protein kinase genetic 1 1 1 Negative Genetic
ERG27 YLR100W 3-keto sterol reductase genetic 1 1 1 Negative Genetic
RTN2 YDL204W Reticulon protein physical 1 1 1 Two-hybrid
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 1 1 1 Two-hybrid
ARE2 YNR019W Acyl-CoA:sterol acyltransferase genetic 1 1 1 Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence physical 1 1 1 Affinity Capture-Western
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Phenotypic Suppression
LSC1 YOR142W Alpha subunit of succinyl-CoA ligase genetic 1 1 1 Negative Genetic
PTP2 YOR208W Phosphotyrosine-specific phosphatase physical 1 1 1 Two-hybrid
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Negative Genetic
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Synthetic Lethality
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Negative Genetic
MAD2 YJL030W Component of the spindle-assembly checkpoint complex genetic 1 1 1 Negative Genetic
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
RGA1 YOR127W GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) physical 1 1 1 Two-hybrid
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor physical 1 1 1 Two-hybrid
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase physical 1 1 1 PCA
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Two-hybrid
NIS1 YNL078W Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
GLN3 YER040W Transcriptional activator in nitrogen catabolite repression system physical 1 1 1 Two-hybrid
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
AKR1 YDR264C Palmitoyl transferase involved in protein palmitoylation genetic 1 1 1 Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein genetic 1 1 1 Phenotypic Suppression
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p physical 1 1 1 Two-hybrid
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Two-hybrid
THO2 YNL139C Subunit of the THO complex physical 1 1 1 Two-hybrid
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein physical 1 1 1 Two-hybrid
STE20 YHL007C Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Suppression
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity physical 1 1 1 Two-hybrid
UBP7 YIL156W Ubiquitin-specific protease that cleaves ubiquitin-protein fusions physical 1 1 1 Two-hybrid
YJR115W YJR115W Putative protein of unknown function physical 1 1 1 Two-hybrid
TMN3 YER113C Protein with a role in cellular adhesion and filamentous growth physical 1 1 1 PCA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family physical 1 1 1 PCA
SRO7 YPR032W Effector of Rab GTPase Sec4p physical 1 1 1 PCA
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
UBI4 YLL039C Ubiquitin physical 1 1 1 Two-hybrid
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway physical 1 1 1 Two-hybrid
WSC2 YNL283C Sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway genetic 1 1 1 Phenotypic Suppression
YHL048C-A YHL048C-A Putative protein of unknown function physical 1 1 1 Two-hybrid
YLR154C-G YLR154C-G Putative protein of unknown function physical 1 1 1 Two-hybrid
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression physical 1 1 1 Two-hybrid
SLN1 YIL147C Transmembrane histidine phosphotransfer kinase and osmosensor genetic 1 1 1 Synthetic Lethality
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Positive Genetic
STE12 YHR084W Transcription factor that is activated by a MAPK signaling cascade genetic 1 1 1 Synthetic Lethality
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
SSK22 YCR073C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Synthetic Growth Defect
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 1 1 1 Negative Genetic
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Synthetic Haploinsufficiency
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
VRG4 YGL225W Golgi GDP-mannose transporter genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Negative Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Negative Genetic
WHI3 YNL197C RNA binding protein that modulates mRNA stability genetic 1 1 1 Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 1 1 1 Negative Genetic
STE6 YKL209C Plasma membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 1 1 1 Negative Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Negative Genetic
SPA2 YLL021W Component of the polarisome genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 1 1 1 Synthetic Growth Defect
PBP1 YGR178C Component of glucose deprivation induced stress granules physical 1 1 1 Two-hybrid
CCH1 YGR217W Voltage-gated high-affinity calcium channel genetic 1 1 1 Negative Genetic
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 1 1 1 Negative Genetic
INN1 YNL152W Essential protein that associates with contractile actomyosin ring genetic 1 1 1 Synthetic Growth Defect
RPL19B YBL027W Ribosomal 60S subunit protein L19B genetic 1 1 1 Negative Genetic
KAR5 YMR065W Protein required for nuclear membrane fusion during karyogamy physical 1 1 1 PCA
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
GEX1 YCL073C Proton:glutathione antiporter physical 1 1 1 Two-hybrid
BCH2 YKR027W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family physical 1 1 1 Two-hybrid
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
BOL3 YAL046C Protein involved in Fe-S cluster transfer to mitochondrial clients physical 1 1 1 Two-hybrid
NGR1 YBR212W RNA binding protein that negatively regulates growth rate genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
FTR1 YER145C High affinity iron permease genetic 1 1 1 Negative Genetic
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein physical 1 1 1 Two-hybrid
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 1 1 1 Two-hybrid
FPS1 YLL043W Aquaglyceroporin, plasma membrane channel genetic 1 1 1 Phenotypic Enhancement
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family physical 1 1 1 PCA
COS4 YFL062W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Negative Genetic
HVG1 YER039C Protein of unknown function physical 1 1 1 PCA
AAD14 YNL331C Putative aryl-alcohol dehydrogenase physical 1 1 1 Two-hybrid
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ENA1 YDR040C P-type ATPase sodium pump physical 1 1 1 Two-hybrid
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 1 1 1 Negative Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
RPE1 YJL121C D-ribulose-5-phosphate 3-epimerase genetic 1 1 1 Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 1 1 1 Negative Genetic
DSE2 YHR143W Daughter cell-specific secreted protein with similarity to glucanases physical 1 1 1 Two-hybrid
DFG10 YIL049W Probable polyprenol reductase genetic 1 1 1 Negative Genetic
AVT5 YBL089W Putative transporter genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention physical 1 1 1 PCA
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Growth Defect
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
COS6 YGR295C Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
DIT2 YDR402C N-formyltyrosine oxidase genetic 1 1 1 Negative Genetic
SEO1 YAL067C Putative permease physical 1 1 1 PCA
LAS21 YJL062W Mannose-ethanolamine phosphotransferase physical 1 1 1 PCA
MCH2 YKL221W Protein with similarity to mammalian monocarboxylate permeases physical 1 1 1 PCA
DGK1 YOR311C Diacylglycerol kinase physical 1 1 1 PCA
PER1 YCR044C Protein of the endoplasmic reticulum genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex physical 1 1 1 PCA
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic