GEnome-wide tool for Multi-scale Modeling
data Extraction and Representation
for Saccharomyces cerevisiae

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.

Standard name	Systematic name	Name description	Type	#Experiments	#Methods	#Publications	Evidence
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	genetic	12	5	11	Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic, Dosage Rescue, Negative Genetic, Negative Genetic
SWI6	YLR182W	Transcription cofactor	physical	10	5	7	Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, PCA, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
HSL1	YKL101W	Nim1p-related protein kinase	genetic	7	1	6	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
NRM1	YNR009W	Transcriptional co-repressor of MBF-regulated gene expression	physical	5	2	3	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
ELM1	YKL048C	Serine/threonine protein kinase	genetic	4	1	4	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIC1	YLR079W	Cyclin-dependent kinase inhibitor (CKI)	genetic	4	1	3	Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
MSA1	YOR066W	Activator of G1-specific transcription factors MBF and SBF	physical	4	2	2	Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPN10	YHR200W	Proteasome polyubiquitin receptor	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
GET2	YER083C	Subunit of the GET complex	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
CIK1	YMR198W	Kinesin-associated protein	genetic	3	1	3	Negative Genetic, Negative Genetic, Negative Genetic
SKN7	YHR206W	Nuclear response regulator and transcription factor	genetic	3	2	1	Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression
CIP1	YPL014W	Cyclin-dependent kinase inhibitor	regulation	2	2	2	chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
RNR1	YER070W	Major isoform of large subunit of ribonucleotide-diphosphate reductase	regulation	2	2	2	chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	physical	2	2	2	Affinity Capture-Western, Co-localization
MNN10	YDR245W	Subunit of a Golgi mannosyltransferase complex	genetic	2	2	2	Synthetic Growth Defect, Negative Genetic
PKC1	YBL105C	Protein serine/threonine kinase	genetic	2	2	2	Synthetic Lethality, Phenotypic Suppression
CLN1	YMR199W	G1 cyclin involved in regulation of the cell cycle	genetic	2	2	2	Dosage Rescue, Negative Genetic
BUB3	YOR026W	Kinetochore checkpoint WD40 repeat protein	genetic	2	2	2	Phenotypic Enhancement, Negative Genetic
CDC55	YGL190C	Regulatory subunit B of protein phosphatase 2A (PP2A)	genetic	2	1	2	Negative Genetic, Negative Genetic
SCC2	YDR180W	Subunit of cohesin loading factor (Scc2p-Scc4p)	genetic	2	1	2	Negative Genetic, Negative Genetic
RPN12	YFR052W	Subunit of the 19S regulatory particle of the 26S proteasome lid	genetic	2	1	2	Negative Genetic, Negative Genetic
SMC3	YJL074C	Subunit of the multiprotein cohesin complex	genetic	2	1	2	Negative Genetic, Negative Genetic
PRI2	YKL045W	Subunit of DNA primase	genetic	2	1	2	Negative Genetic, Negative Genetic
MMR1	YLR190W	Phosphorylated protein of the mitochondrial outer membrane	genetic	2	1	2	Negative Genetic, Negative Genetic
TPM1	YNL079C	Major isoform of tropomyosin	genetic	2	1	2	Positive Genetic, Positive Genetic
ANP1	YEL036C	Subunit of the alpha-1,6 mannosyltransferase complex	genetic	2	1	2	Negative Genetic, Negative Genetic
BCK2	YER167W	Serine/threonine-rich protein involved in PKC1 signaling pathway	genetic	2	1	2	Phenotypic Suppression, Phenotypic Suppression
AVO2	YMR068W	Component of a complex containing the Tor2p kinase and other proteins	genetic	2	1	2	Negative Genetic, Negative Genetic
BUB1	YGR188C	Protein kinase involved in the cell cycle checkpoint into anaphase	genetic	2	1	2	Negative Genetic, Negative Genetic
LRS4	YDR439W	Nucleolar protein that forms a complex with Csm1p	genetic	2	1	2	Positive Genetic, Positive Genetic
SWI6	YLR182W	Transcription cofactor	genetic	2	2	1	Synthetic Rescue, Dosage Rescue
SKN7	YHR206W	Nuclear response regulator and transcription factor	physical	2	2	1	Reconstituted Complex, Two-hybrid
AIM3	YBR108W	Protein that inhibits barbed-end actin filament elongation	genetic	2	1	1	Positive Genetic, Positive Genetic
MSA1	YOR066W	Activator of G1-specific transcription factors MBF and SBF	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
AGE1	YDR524C	ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MNN5	YJL186W	Alpha-1,2-mannosyltransferase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CAP1	YKL007W	Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
DNF2	YDR093W	Aminophospholipid translocase (flippase)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SEN1	YLR430W	ATP-dependent 5' to 3' RNA/DNA and DNA helicase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GAS1	YMR307W	Beta-1,3-glucanosyltransferase required for cell wall assembly	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
POL12	YBL035C	B subunit of DNA polymerase alpha-primase complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CLB6	YGR109C	B-type cyclin involved in DNA replication during S phase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CLB5	YPR120C	B-type cyclin involved in DNA replication during S phase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
POL1	YNL102W	Catalytic subunit of the DNA polymerase I alpha-primase complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
DUN1	YDL101C	Cell-cycle checkpoint S/T protein kinase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SCW10	YMR305C	Cell wall protein with similarity to glucanases	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
LAC1	YKL008C	Ceramide synthase component	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CHS1	YNL192W	Chitin synthase I	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CRH1	YGR189C	Chitin transglycosylase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PCL1	YNL289W	Cyclin, interacts with cyclin-dependent kinase Pho85p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HST2	YPL015C	Cytoplasmic NAD(+)-dependent protein deacetylase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SWI4	YER111C	DNA binding component of the SBF complex (Swi4p-Swi6p)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RAD53	YPL153C	DNA damage response kinase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
JEM1	YJL073W	DnaJ-like chaperone required for nuclear membrane fusion during mating	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC45	YLR103C	DNA replication initiation factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PPN1	YDR452W	Dual endo- and exopolyphosphatase with a role in phosphate metabolism	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ELO1	YJL196C	Elongase I, medium-chain acyl elongase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
VAC14	YLR386W	Enzyme regulator	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MCD1	YDL003W	Essential alpha-kleisin subunit of the cohesin complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC6	YJL194W	Essential ATP-binding protein required for DNA replication	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
EMW1	YNL313C	Essential conserved protein with a role in cell wall integrity	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SIT1	YEL065W	Ferrioxamine B transporter	regulation	1	1	1	DNA to cDNA expression microarray evidence
FET3	YMR058W	Ferro-O2-oxidoreductase	regulation	1	1	1	DNA to cDNA expression microarray evidence
HCM1	YCR065W	Forkhead transcription factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CLN1	YMR199W	G1 cyclin involved in regulation of the cell cycle	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
KRE6	YPR159W	Glucosyl hydrolase required for beta-1,6-glucan biosynthesis	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GOR1	YNL274C	Glyoxylate reductase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ECM33	YBR078W	GPI-anchored protein involved in efficient glucose uptake	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YHP1	YDR451C	Homeobox transcriptional repressor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YOX1	YML027W	Homeobox transcriptional repressor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
APJ1	YNL077W	Hsp40 chaperone with a role in SUMO-mediated protein degradation	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SKG6	YHR149C	Integral membrane protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
AXL2	YIL140W	Integral plasma membrane protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
LSM4	YER112W	Lsm (Like Sm) protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
EXG1	YLR300W	Major exo-1,3-beta-glucanase of the cell wall	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ALG9	YNL219C	Mannosyltransferase, involved in N-linked glycosylation	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPO16	YHR153C	Meiosis-specific protein involved in synaptonemal complex assembly	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ERV25	YML012W	Member of the p24 family involved in ER to Golgi transport	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PET54	YGR222W	Mitochondrial inner membrane protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
DIN7	YDR263C	Mitochondrial nuclease functioning in DNA repair and replication	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HSL1	YKL101W	Nim1p-related protein kinase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ASF1	YJL115W	Nucleosome assembly factor	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PAC10	YGR078C	Part of the heteromeric co-chaperone GimC/prefoldin complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RRD2	YPL152W	Peptidyl-prolyl cis/trans-isomerase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PEX28	YHR150W	Peroxisomal integral membrane peroxin	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SEC14	YMR079W	Phosphatidylinositol/phosphatidylcholine transfer protein	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PDR16	YNL231C	Phosphatidylinositol transfer protein (PITP)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
BUD9	YGR041W	Protein involved in bud-site selection	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TOS2	YGR221C	Protein involved in localization of Cdc24p to the site of bud growth	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
NCA3	YJL116C	Protein involved in mitochondrion organization	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
HLR1	YDR528W	Protein involved in regulation of cell wall composition and integrity	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
FKS3	YMR306W	Protein involved in spore wall assembly	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RBA50	YDR527W	Protein involved in transcription	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GIN4	YDR507C	Protein kinase involved in bud growth and assembly of the septin ring	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SWE1	YJL187C	Protein kinase that regulates the G2/M transition	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SWC7	YLR385C	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CSA1	YPR174C	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YLR297W	YLR297W	Protein of unknown function	regulation	1	1	1	DNA to cDNA expression microarray evidence
SNA2	YDR525W-A	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YPL152W-A	YPL152W-A	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
DIA1	YMR316W	Protein of unknown function	regulation	1	1	1	DNA to cDNA expression microarray evidence
YGR079W	YGR079W	Protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MSH6	YDR097C	Protein required for mismatch repair in mitosis and meiosis	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SPT21	YMR179W	Protein with a role in transcriptional silencing	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MGS1	YNL218W	Protein with DNA-dependent ATPase and ssDNA annealing activities	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ERP3	YDL018C	Protein with similarity to Emp24p and Erv25p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ERP5	YHR110W	Protein with similarity to Emp24p and Erv25p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
THI22	YPR121W	Protein with similarity to hydroxymethylpyrimidine phosphate kinases	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ACM1	YPL267W	Pseudosubstrate inhibitor of the APC/C	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
ATR2	YMR279C	Putative boron transporter involved in boron efflux and resistance	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MRX14	YDR115W	Putative mitochondrial ribosomal protein of the large subunit	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RBH2	YJR030C	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
LCL2	YLR104W	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YDR524W-C	YDR524W-C	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YDR524C-B	YDR524C-B	Putative protein of unknown function	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MSA2	YKR077W	Putative transcriptional activator	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YGR109W-B	YGR109W-B	Retrotransposon TYA Gag and TYB Pol genes	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
YGR109W-A	YGR109W-A	Retrotransposon TYA Gag gene co-transcribed with TYB Pol	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GIC2	YDR309C	Rho-family GTPase interacting protein and Cdc42p effector	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
GIC1	YHR061C	Rho-family GTPase interacting protein and Cdc42p effector	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
DPB2	YPR175W	Second largest subunit of DNA polymerase II (DNA polymerase epsilon)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
PDS1	YDR113C	Securin	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
MRC1	YCL061C	S-phase checkpoint protein required for DNA replication	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SUR2	YDR297W	Sphinganine C4-hydroxylase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC7	YDL017W	S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RAD51	YER095W	Strand exchange protein	regulation	1	1	1	DNA to cDNA expression microarray evidence
CTF18	YMR078C	Subunit of a complex with Ctf8p	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
TOF1	YNL273W	Subunit of a replication-pausing checkpoint complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
IKI3	YLR384C	Subunit of Elongator complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RFA2	YNL312W	Subunit of heterotrimeric Replication Protein A (RPA)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
RFA1	YAR007C	Subunit of heterotrimeric Replication Protein A (RPA)	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
IRR1	YIL026C	Subunit of the cohesin complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SLM4	YBR077C	Subunit of the EGO/GSE complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SMC3	YJL074C	Subunit of the multiprotein cohesin complex	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SEN34	YAR008W	Subunit of the tRNA splicing endonuclease	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
POL32	YJR043C	Third subunit of DNA polymerase delta	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CDC21	YOR074C	Thymidylate synthase	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
NRM1	YNR009W	Transcriptional co-repressor of MBF-regulated gene expression	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
SHO1	YER118C	Transmembrane osmosensor for filamentous growth and HOG pathways	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
UFE1	YOR075W	t-SNARE protein required for retrograde vesicular traffic	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
APE1	YKL103C	Vacuolar aminopeptidase yscI	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
AVT1	YJR001W	Vacuolar transporter	regulation	1	1	1	chromatin immunoprecipitation-chip evidence
CTR9	YOL145C	Component of the Paf1p complex involved in transcription elongation	genetic	1	1	1	Negative Genetic
DSN1	YIR010W	Essential component of the outer kinetochore MIND complex	physical	1	1	1	Affinity Capture-MS
CDC42	YLR229C	Small rho-like GTPase	genetic	1	1	1	Synthetic Rescue
CCR4	YAL021C	Component of the CCR4-NOT transcriptional complex	physical	1	1	1	Affinity Capture-RNA
BEM1	YBR200W	Protein containing SH3-domains	genetic	1	1	1	Positive Genetic
BEM2	YER155C	Rho GTPase activating protein (RhoGAP)	genetic	1	1	1	Positive Genetic
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	physical	1	1	1	PCA
CDC28	YBR160W	Cyclin-dependent kinase (CDK) catalytic subunit	genetic	1	1	1	Synthetic Growth Defect
CKS1	YBR135W	Cyclin-dependent protein kinase regulatory subunit and adaptor	genetic	1	1	1	Negative Genetic
DHH1	YDL160C	Cytoplasmic DEAD-box helicase and mRNA decapping activator	physical	1	1	1	Affinity Capture-RNA
ISW1	YBR245C	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers	physical	1	1	1	Affinity Capture-RNA
PRP19	YLL036C	Splicing factor associated with the spliceosome	physical	1	1	1	Co-purification
SSK22	YCR073C	MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway	physical	1	1	1	Biochemical Activity
YCK2	YNL154C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	physical	1	1	1	Biochemical Activity
YCK2	YNL154C	Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform	genetic	1	1	1	Positive Genetic
RAD53	YPL153C	DNA damage response kinase	physical	1	1	1	Affinity Capture-MS
SPC25	YER018C	Component of the kinetochore-associated Ndc80 complex	physical	1	1	1	Two-hybrid
VTI1	YMR197C	Protein involved in cis-Golgi membrane traffic	physical	1	1	1	Two-hybrid
SPO14	YKR031C	Phospholipase D	physical	1	1	1	Two-hybrid
MSA2	YKR077W	Putative transcriptional activator	physical	1	1	1	Affinity Capture-Western
TEC1	YBR083W	Transcription factor targeting filamentation genes and Ty1 expression	physical	1	1	1	Affinity Capture-Western
SPT10	YJL127C	Histone H3 acetylase with a role in transcriptional regulation	physical	1	1	1	Affinity Capture-MS
SPT10	YJL127C	Histone H3 acetylase with a role in transcriptional regulation	genetic	1	1	1	Synthetic Growth Defect
PUF3	YLL013C	Protein of the mitochondrial outer surface	physical	1	1	1	Affinity Capture-RNA
PUF2	YPR042C	PUF family mRNA-binding protein	physical	1	1	1	Affinity Capture-RNA
PUB1	YNL016W	Poly (A)+ RNA-binding protein	physical	1	1	1	Affinity Capture-MS
PAF1	YBR279W	Component of the Paf1p complex involved in transcription elongation	genetic	1	1	1	Dosage Rescue
RAP1	YNL216W	Essential DNA-binding transcription regulator that binds many loci	genetic	1	1	1	Synthetic Rescue
RBL2	YOR265W	Protein involved in microtubule morphogenesis	genetic	1	1	1	Phenotypic Enhancement
POL32	YJR043C	Third subunit of DNA polymerase delta	genetic	1	1	1	Negative Genetic
RPN4	YDL020C	Transcription factor that stimulates expression of proteasome genes	genetic	1	1	1	Negative Genetic
NHP10	YDL002C	Non-essential INO80 chromatin remodeling complex subunit	genetic	1	1	1	Negative Genetic
THP1	YOL072W	Nuclear pore-associated protein	genetic	1	1	1	Negative Genetic
RAD61	YDR014W	Subunit of a complex that inhibits sister chromatid cohesion	genetic	1	1	1	Negative Genetic
RLM1	YPL089C	MADS-box transcription factor	genetic	1	1	1	Synthetic Growth Defect
SSE1	YPL106C	ATPase component of heat shock protein Hsp90 chaperone complex	genetic	1	1	1	Synthetic Growth Defect
YPD1	YDL235C	Osmotic stress-responsive phosphorelay intermediate sensor protein	genetic	1	1	1	Positive Genetic
STB1	YNL309W	Protein with role in regulation of MBF-specific transcription at Start	genetic	1	1	1	Phenotypic Enhancement
TOP1	YOL006C	Topoisomerase I	genetic	1	1	1	Synthetic Growth Defect
RTS1	YOR014W	B-type regulatory subunit of protein phosphatase 2A (PP2A)	genetic	1	1	1	Synthetic Growth Defect
RML2	YEL050C	Mitochondrial ribosomal protein of the large subunit (L2)	genetic	1	1	1	Positive Genetic
MSC1	YML128C	Protein of unknown function	genetic	1	1	1	Positive Genetic
SEC63	YOR254C	Essential subunit of Sec63 complex	genetic	1	1	1	Negative Genetic
SPT21	YMR179W	Protein with a role in transcriptional silencing	genetic	1	1	1	Synthetic Rescue
RRP6	YOR001W	Nuclear exosome exonuclease component	genetic	1	1	1	Negative Genetic
UBP8	YMR223W	Ubiquitin-specific protease component of the SAGA acetylation complex	genetic	1	1	1	Negative Genetic
SOD1	YJR104C	Cytosolic copper-zinc superoxide dismutase	genetic	1	1	1	Negative Genetic
SGF73	YGL066W	Subunit of DUBm module of SAGA and SLIK	genetic	1	1	1	Negative Genetic
UBP3	YER151C	Ubiquitin-specific protease that cleaves Ub-protein fusions	genetic	1	1	1	Negative Genetic
STB6	YKL072W	Protein that binds Sin3p in a two-hybrid assay	genetic	1	1	1	Positive Genetic
SSN3	YPL042C	Component of the RNA polymerase II mediator complex	genetic	1	1	1	Positive Genetic
SOK2	YMR016C	Nuclear protein that negatively regulates pseudohyphal differentiation	genetic	1	1	1	Negative Genetic
RAD17	YOR368W	Checkpoint protein	genetic	1	1	1	Positive Genetic
MET32	YDR253C	Zinc-finger DNA-binding transcription factor	genetic	1	1	1	Negative Genetic
MCM2	YBL023C	Protein involved in DNA replication	genetic	1	1	1	Synthetic Rescue
TEL2	YGR099W	Subunit of the ASTRA complex, involved in chromatin remodeling	genetic	1	1	1	Positive Genetic
SLT2	YHR030C	Serine/threonine MAP kinase	genetic	1	1	1	Dosage Growth Defect
RTT107	YHR154W	BRCA1 C-terminal domain protein needed for recovery from DNA damage	genetic	1	1	1	Negative Genetic
STU1	YBL034C	Microtubule plus-end-tracking non-motor protein	genetic	1	1	1	Positive Genetic
STU2	YLR045C	Microtubule polymerase of the XMAP215/Dis1 family	genetic	1	1	1	Positive Genetic
PBR1	YNL181W	Putative oxidoreductase	genetic	1	1	1	Positive Genetic
RPL3	YOR063W	Ribosomal 60S subunit protein L3	genetic	1	1	1	Positive Genetic
MTR10	YOR160W	Nuclear import receptor	genetic	1	1	1	Positive Genetic
YDR524C-B	YDR524C-B	Putative protein of unknown function	genetic	1	1	1	Positive Genetic
MEF2	YJL102W	Mitochondrial elongation factor involved in translational elongation	genetic	1	1	1	Positive Genetic
ROM2	YLR371W	Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p	genetic	1	1	1	Positive Genetic
TUS1	YLR425W	Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity	genetic	1	1	1	Positive Genetic
MRPL19	YNL185C	Mitochondrial ribosomal protein of the large subunit	genetic	1	1	1	Positive Genetic
MGM1	YOR211C	Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p	genetic	1	1	1	Positive Genetic
MRPS16	YPL013C	Mitochondrial ribosomal protein of the small subunit	genetic	1	1	1	Positive Genetic
TAO3	YIL129C	Component of the RAM signaling network	genetic	1	1	1	Negative Genetic
TAH11	YJR046W	DNA replication licensing factor	genetic	1	1	1	Negative Genetic
POL2	YNL262W	Catalytic subunit of DNA polymerase (II) epsilon	genetic	1	1	1	Negative Genetic
SMC5	YOL034W	Subunit of the SMC5-SMC6 complex	genetic	1	1	1	Negative Genetic
RPT4	YOR259C	ATPase of the 19S regulatory particle of the 26S proteasome	genetic	1	1	1	Negative Genetic
RPN8	YOR261C	Essential non-ATPase regulatory subunit of the 26S proteasome	genetic	1	1	1	Negative Genetic
PZF1	YPR186C	Transcription factor IIIA (TFIIIA)	genetic	1	1	1	Negative Genetic
PDX3	YBR035C	Pyridoxine (pyridoxamine) phosphate oxidase	genetic	1	1	1	Negative Genetic
YBR220C	YBR220C	Putative protein of unknown function	genetic	1	1	1	Negative Genetic
RVS167	YDR388W	Calmodulin-binding actin-associated protein	genetic	1	1	1	Negative Genetic
RPL27B	YDR471W	Ribosomal 60S subunit protein L27B	genetic	1	1	1	Negative Genetic
RPA34	YJL148W	RNA polymerase I subunit A34.5	genetic	1	1	1	Negative Genetic
MOG1	YJR074W	Conserved nuclear protein that interacts with GTP-Gsp1p	genetic	1	1	1	Negative Genetic
SIN3	YOL004W	Component of both the Rpd3S and Rpd3L histone deacetylase complexes	genetic	1	1	1	Negative Genetic
TMH11	YJR085C	Mitochondrial protein of unknown function	genetic	1	1	1	Negative Genetic
SSO2	YMR183C	Plasma membrane t-SNARE	genetic	1	1	1	Negative Genetic
VAC7	YNL054W	Integral vacuolar membrane protein	genetic	1	1	1	Negative Genetic
RPA49	YNL248C	RNA polymerase I subunit A49	genetic	1	1	1	Negative Genetic
STD1	YOR047C	Protein involved in control of glucose-regulated gene expression	genetic	1	1	1	Negative Genetic
WHI5	YOR083W	Repressor of G1 transcription	genetic	1	1	1	Dosage Growth Defect
SSN8	YNL025C	Cyclin-like component of RNA polymerase II holoenzyme	genetic	1	1	1	Positive Genetic
RSC1	YGR056W	Component of the RSC chromatin remodeling complex	genetic	1	1	1	Positive Genetic
RPS11B	YBR048W	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
RPS19A	YOL121C	Protein component of the small (40S) ribosomal subunit	genetic	1	1	1	Positive Genetic
RNR3	YIL066C	Minor isoform of large subunit of ribonucleotide-diphosphate reductase	genetic	1	1	1	Negative Genetic
TUB4	YLR212C	Gamma-tubulin	genetic	1	1	1	Synthetic Rescue
SGS1	YMR190C	RecQ family nucleolar DNA helicase	genetic	1	1	1	Negative Genetic
CMD1	YBR109C	Calmodulin	genetic	1	1	1	Negative Genetic
GIM3	YNL153C	Subunit of the heterohexameric cochaperone prefoldin complex	genetic	1	1	1	Positive Genetic
HTA1	YDR225W	Histone H2A	genetic	1	1	1	Positive Genetic
ABF2	YMR072W	Mitochondrial DNA-binding protein	genetic	1	1	1	Negative Genetic
LTE1	YAL024C	Protein similar to GDP/GTP exchange factors	genetic	1	1	1	Synthetic Growth Defect
HEK2	YBL032W	RNA binding protein involved in asymmetric localization of ASH1 mRNA	physical	1	1	1	Affinity Capture-RNA
CDC13	YDL220C	Single stranded DNA-binding protein found at TG1-3 telomere G-tails	genetic	1	1	1	Negative Genetic
CAF20	YOR276W	Phosphoprotein of the mRNA cap-binding complex	physical	1	1	1	Affinity Capture-RNA
HTB1	YDR224C	Histone H2B	genetic	1	1	1	Positive Genetic
FKH1	YIL131C	Forkhead family transcription factor	physical	1	1	1	Affinity Capture-MS
GET1	YGL020C	Subunit of the GET complex	genetic	1	1	1	Negative Genetic
DUN1	YDL101C	Cell-cycle checkpoint S/T protein kinase	genetic	1	1	1	Negative Genetic
ERG10	YPL028W	Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase)	genetic	1	1	1	Negative Genetic
FAR10	YLR238W	Protein involved in recovery from arrest in response to pheromone	genetic	1	1	1	Negative Genetic
HSL7	YBR133C	Protein arginine N-methyltransferase	genetic	1	1	1	Negative Genetic
MAK11	YKL021C	Protein involved in an early step of 60S ribosomal subunit biogenesis	genetic	1	1	1	Negative Genetic
HOG1	YLR113W	Mitogen-activated protein kinase involved in osmoregulation	genetic	1	1	1	Dosage Growth Defect
HOM3	YER052C	Aspartate kinase (L-aspartate 4-P-transferase)	genetic	1	1	1	Negative Genetic
HAL5	YJL165C	Snf1p-related nutrient-responsive protein kinase	physical	1	1	1	Biochemical Activity
ECM33	YBR078W	GPI-anchored protein involved in efficient glucose uptake	genetic	1	1	1	Negative Genetic
CLN2	YPL256C	G1 cyclin involved in regulation of the cell cycle	genetic	1	1	1	Dosage Rescue
CDH1	YGL003C	Activator of anaphase-promoting complex/cyclosome (APC/C)	genetic	1	1	1	Negative Genetic
BIR1	YJR089W	Subunit of chromosomal passenger complex (CPC)	genetic	1	1	1	Positive Genetic
ESS1	YJR017C	Peptidylprolyl-cis/trans-isomerase (PPIase)	genetic	1	1	1	Synthetic Rescue
CTK3	YML112W	Gamma subunit of C-terminal domain kinase I	genetic	1	1	1	Positive Genetic
CLN3	YAL040C	G1 cyclin involved in cell cycle progression	genetic	1	1	1	Phenotypic Suppression
AFT1	YGL071W	Transcription factor involved in iron utilization and homeostasis	genetic	1	1	1	Positive Genetic
IPL1	YPL209C	Aurora kinase of chromosomal passenger complex	genetic	1	1	1	Synthetic Rescue
CSE4	YKL049C	Centromeric histone H3-like protein	genetic	1	1	1	Negative Genetic
BUR6	YER159C	Subunit of a heterodimeric NC2 transcription regulator complex	genetic	1	1	1	Positive Genetic
MBF1	YOR298C-A	Transcriptional coactivator	genetic	1	1	1	Positive Genetic
CLA4	YNL298W	Cdc42p-activated signal transducing kinase	genetic	1	1	1	Negative Genetic
HSP26	YBR072W	Small heat shock protein (sHSP) with chaperone activity	genetic	1	1	1	Negative Genetic
HRQ1	YDR291W	3'-5' DNA helicase of the conserved RecQ family	genetic	1	1	1	Negative Genetic
KCS1	YDR017C	Inositol hexakisphosphate and inositol heptakisphosphate kinase	genetic	1	1	1	Negative Genetic
IMP21	YIL154C	Transcriptional activator involved in maintenance of ion homeostasis	genetic	1	1	1	Negative Genetic
ABZ2	YMR289W	Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase)	genetic	1	1	1	Negative Genetic
CDC8	YJR057W	Nucleoside monophosphate and nucleoside diphosphate kinase	genetic	1	1	1	Negative Genetic
ISC1	YER019W	Inositol phosphosphingolipid phospholipase C	genetic	1	1	1	Negative Genetic
EDC1	YGL222C	RNA-binding protein that activates mRNA decapping directly	genetic	1	1	1	Negative Genetic