ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
17 |
4 |
14 |
Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Enhancement, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue, Synthetic Growth Defect, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
10 |
3 |
7 |
Negative Genetic, Synthetic Rescue, Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Synthetic Rescue |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
7 |
3 |
5 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
7 |
3 |
5 |
Negative Genetic, Negative Genetic, Synthetic Rescue, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
6 |
1 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCM22 |
YJR135C |
Outer kinetochore protein and component of the Ctf3 subcomplex |
genetic |
6 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
6 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
5 |
2 |
5 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
5 |
3 |
4 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Negative Genetic, Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
5 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IML3 |
YBR107C |
Outer kinetochore protein and component of the Ctf19 complex |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
5 |
2 |
4 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
physical |
5 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
physical |
4 |
2 |
4 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
4 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality |
CHL4 |
YDR254W |
Outer kinetochore protein required for chromosome stability |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
IRC15 |
YPL017C |
Microtubule associated protein |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
3 |
3 |
3 |
Phenotypic Suppression, Negative Genetic, Phenotypic Enhancement |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
3 |
3 |
3 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
3 |
3 |
2 |
Synthetic Growth Defect, Phenotypic Enhancement, Synthetic Rescue |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRR1 |
YIL026C |
Subunit of the cohesin complex |
physical |
3 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
HXT1 |
YHR094C |
Low-affinity glucose transporter of the major facilitator superfamily |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
2 |
2 |
2 |
Phenotypic Suppression, Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
2 |
2 |
2 |
Dosage Growth Defect, Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
1 |
2 |
Dosage Rescue, Dosage Rescue |
MAG1 |
YER142C |
3-methyl-adenine DNA glycosylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NCW2 |
YLR194C |
GPI-anchored protein involved in cell wall remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IDP3 |
YNL009W |
Peroxisomal NADP-dependent isocitrate dehydrogenase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ORM1 |
YGR038W |
Protein that mediates sphingolipid homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAS4 |
YOL132W |
1,3-beta-glucanosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YLL056C |
YLL056C |
NADH-dependent aldehyde reductase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SKG3 |
YLR187W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RED1 |
YLR263W |
Protein component of the synaptonemal complex axial elements |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YLR415C |
YLR415C |
Putative protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPG4 |
YMR107W |
Protein required for high temperature survival during stationary phase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
2 |
1 |
2 |
Phenotypic Enhancement, Phenotypic Enhancement |
OAF3 |
YKR064W |
Putative transcriptional repressor with Zn(2)-Cys(6) finger |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BNI1 |
YNL271C |
Formin |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HLJ1 |
YMR161W |
Co-chaperone for Hsp40p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RFC2 |
YJR068W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMG1 |
YLR186W |
Methyltransferase for rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HST1 |
YOL068C |
NAD(+)-dependent histone deacetylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
INP2 |
YMR163C |
Peroxisome-specific receptor important for peroxisome inheritance |
genetic |
1 |
1 |
1 |
Negative Genetic |
MBP1 |
YDL056W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPH1 |
YIR002C |
3'-5' DNA helicase involved in error-free bypass of DNA lesions |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GYP6 |
YJL044C |
GTPase-activating protein (GAP) for yeast Rab family member Ypt6p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD59 |
YDL059C |
Protein involved DNA double-strand break repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CSM2 |
YIL132C |
Subunit of the Shu complex (aka PCSS complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAC1 |
YMR021C |
Copper-sensing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM27 |
YJR106W |
Protein involved in calcium homeostasis and exit from quiescence |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX28 |
YHR150W |
Peroxisomal integral membrane peroxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC3 |
YDR332W |
Double-stranded DNA-dependent helicase of the DExH/D-box family |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN4 |
YOR168W |
Glutamine tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL27 |
YBR282W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX9 |
YDL027C |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
1 |
1 |
1 |
Negative Genetic |
APE4 |
YHR113W |
Cytoplasmic aspartyl aminopeptidase with possible vacuole function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
EFM4 |
YIL064W |
Lysine methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
SCM3 |
YDL139C |
Nonhistone component of centromeric chromatin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEX1 |
YNL253W |
Protein involved in mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT105 |
YER104W |
Chaperone for Replication Protein A complex (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
RBL2 |
YOR265W |
Protein involved in microtubule morphogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP1 |
YOL006C |
Topoisomerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Positive Genetic |
TDA5 |
YLR426W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIM54 |
YJL054W |
Component of the mitochondrial TIM22 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCC4 |
YER147C |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF11 |
YML015C |
TFIID subunit (40 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP5 |
YMR229C |
RNA binding protein involved in synthesis of 18S and 5.8S rRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPO5 |
YKL174C |
Protein involved in excretion of putrescine and spermidine |
genetic |
1 |
1 |
1 |
Negative Genetic |
REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBP2 |
YGL060W |
Central kinetochore associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR072W-B |
YOR072W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP2 |
YOR124C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRX4 |
YPL168W |
Protein that associates with mitochondrial ribosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |