Standard name Systematic name Name description Description
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle Metalloprotease subunit of 19S regulatory particle; part of 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates; involved, independent of catalytic activity, in fission of mitochondria and peroxisomes; protein abundance increases in response to DNA replication stress
Visualize the interactome of RPN11
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.065 NaN 0.062
Nucleus 0.812 0.795 0.805
Vac/Vac Memb 0.133 0.165 0.108

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 16400

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RPN11 4 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome physical 38 8 32 Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-crystal Structure, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Co-purification, Affinity Capture-Western, Reconstituted Complex
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes physical 34 7 30 Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, PCA, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-purification, PCA, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-Western
RPN10 YHR200W Proteasome polyubiquitin receptor physical 33 5 26 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid physical 29 5 23 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification, Reconstituted Complex
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome physical 28 5 23 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-Western, Reconstituted Complex
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid physical 27 4 24 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome physical 24 5 20 Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 23 5 22 Affinity Capture-Western, Affinity Capture-MS, Co-fractionation, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Co-purification, Reconstituted Complex
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome physical 23 4 22 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification, Affinity Capture-Western
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid physical 23 4 22 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN9 YDR427W Non-ATPase regulatory subunit of the 26S proteasome physical 22 5 21 Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome physical 21 4 20 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome physical 20 4 19 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification
RPN2 YIL075C Subunit of the 26S proteasome physical 20 5 18 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome physical 19 5 18 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Co-fractionation, Affinity Capture-MS, Reconstituted Complex, Co-purification
UBP6 YFR010W Ubiquitin-specific protease physical 18 4 18 Affinity Capture-MS, Co-purification, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome physical 18 4 17 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Co-purification
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome physical 13 4 11 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
PRE1 YER012W Beta 4 subunit of the 20S proteasome physical 12 3 12 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component physical 12 3 10 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification
UBI4 YLL039C Ubiquitin physical 11 5 9 Affinity Capture-Western, Biochemical Activity, Affinity Capture-MS, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Biochemical Activity, Co-crystal Structure, Biochemical Activity, Biochemical Activity, Biochemical Activity
RAD23 YEL037C Protein with ubiquitin-like N terminus physical 10 2 10 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome physical 10 4 8 Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome physical 10 4 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome physical 10 4 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
PRE8 YML092C Alpha 2 subunit of the 20S proteasome physical 10 4 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome physical 10 4 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome physical 10 4 8 Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS
RPN13 YLR421C Subunit of the 19S regulatory particle of the 26S proteasome lid physical 9 4 9 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS
PRE4 YFR050C Beta 7 subunit of the 20S proteasome physical 9 3 9 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-Western
NAS6 YGR232W Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 9 3 6 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
ECM29 YHL030W Scaffold protein physical 9 2 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western
PUP1 YOR157C Beta 2 subunit of the 20S proteasome physical 8 3 8 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein physical 8 3 7 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western
PRE2 YPR103W Beta 5 subunit of the 20S proteasome physical 7 3 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
PRE3 YJL001W Beta 1 subunit of the 20S proteasome physical 7 3 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
PRE7 YBL041W Beta 6 subunit of the 20S proteasome physical 7 3 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-purification, Affinity Capture-MS
PUP3 YER094C Beta 3 subunit of the 20S proteasome physical 7 3 7 Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 5 2 5 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence, chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation- exonuclease evidence
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 5 2 4 Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RPN14 YGL004C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 5 2 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 4 3 4 Affinity Capture-MS, Affinity Capture-MS, Co-crystal Structure, Co-purification
CDC48 YDL126C AAA ATPase with protein-unfoldase activity physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-purification
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 4 2 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-RNA, Affinity Capture-RNA
URA7 YBL039C Major CTP synthase isozyme (see also URA8) physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 4 3 3 Phenotypic Suppression, Positive Genetic, Positive Genetic, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 4 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPT3 YDR394W ATPase of the 19S regulatory particle of the 26S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPN5 YDL147W Subunit of the CSN and 26S proteasome lid complexes genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 4 2 2 Positive Genetic, Positive Genetic, Negative Genetic, Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 4 2 2 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
SCL1 YGL011C Alpha 1 subunit of the 20S proteasome genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PRE10 YOR362C Alpha 7 subunit of the 20S proteasome genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CDC73 YLR418C Component of the Paf1p complex genetic 3 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
RUB1 YDR139C Ubiquitin-like protein with similarity to mammalian NEDD8 genetic 3 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect
DDI1 YER143W Aspartic-type endopeptidase physical 3 2 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 3 2 3 Negative Genetic, Synthetic Lethality, Negative Genetic
ADH1 YOL086C Alcohol dehydrogenase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KAP123 YER110C Karyopherin beta physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
BMH1 YER177W 14-3-3 protein, major isoform physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PAB1 YER165W Poly(A) binding protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SEC53 YFL045C Phosphomannomutase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSA2 YLL024C HSP70 family ATP-binding protein physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SIS1 YNL007C Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YEF3 YLR249W Translation elongation factor 3 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SAM1 YLR180W S-adenosylmethionine synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TIF2 YJL138C Translation initiation factor eIF4A physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS5 YJR123W Protein component of the small (40S) ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SAH1 YER043C S-adenosyl-L-homocysteine hydrolase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TDH1 YJL052W Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
THS1 YIL078W Threonyl-tRNA synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
VAS1 YGR094W Mitochondrial and cytoplasmic valyl-tRNA synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPS2 YGL123W Protein component of the small (40S) subunit physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
YHB1 YGR234W Nitric oxide oxidoreductase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
TSA1 YML028W Thioredoxin peroxidase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
SER1 YOR184W 3-phosphoserine aminotransferase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
KRS1 YDR037W Lysyl-tRNA synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FAS2 YPL231W Alpha subunit of fatty acid synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PGK1 YCR012W 3-phosphoglycerate kinase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
GND1 YHR183W 6-phosphogluconate dehydrogenase (decarboxylating) physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
DPS1 YLL018C Aspartyl-tRNA synthetase, primarily cytoplasmic physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HSP104 YLL026W Disaggregase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
HEF3 YNL014W Translational elongation factor EF-3 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDC60 YPL160W Cytosolic leucyl tRNA synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ERG20 YJL167W Farnesyl pyrophosphate synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
RPL5 YPL131W Ribosomal 60S subunit protein L5 physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
CDC19 YAL038W Pyruvate kinase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ASN1 YPR145W Asparagine synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LEU1 YGL009C Isopropylmalate isomerase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
LYS21 YDL131W Homocitrate synthase isozyme physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ALD6 YPL061W Cytosolic aldehyde dehydrogenase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
FAS1 YKL182W Beta subunit of fatty acid synthetase physical 3 1 3 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 3 3 2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex
STS1 YIR011C Protein required for localizing proteasomes to the nucleus genetic 3 2 2 Negative Genetic, Negative Genetic, Dosage Rescue
SMC3 YJL074C Subunit of the multiprotein cohesin complex genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
BRE1 YDL074C E3 ubiquitin ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SEM1 YDR363W-A 19S proteasome regulatory particle lid subcomplex component genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
YOX1 YML027W Homeobox transcriptional repressor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TMC1 YOR052C AN1-type zinc finger protein, effector of proteotoxic stress response genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLK19 YOR195W Kinetochore-associated protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SCC2 YDR180W Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS24 YKL041W One of four subunits of the ESCRT-III complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PRE6 YOL038W Alpha 4 subunit of the 20S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HHF1 YBR009C Histone H4 genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CLB2 YPR119W B-type cyclin involved in cell cycle progression genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PUP2 YGR253C Alpha 5 subunit of the 20S proteasome genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 3 2 1 Affinity Capture-Western, Affinity Capture-Western, Co-fractionation
STS1 YIR011C Protein required for localizing proteasomes to the nucleus physical 2 2 2 Two-hybrid, Reconstituted Complex
RRI1 YDL216C Catalytic subunit of the COP9 signalosome (CSN) complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 2 2 2 Synthetic Lethality, Positive Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 2 2 2 Affinity Capture-RNA, Affinity Capture-MS
HSM3 YBR272C Evolutionarily conserved 19S regulatory particle assembly-chaperone physical 2 2 2 Affinity Capture-Western, Affinity Capture-MS
CMD1 YBR109C Calmodulin physical 2 2 2 Reconstituted Complex, Affinity Capture-MS
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
RAD23 YEL037C Protein with ubiquitin-like N terminus genetic 2 2 2 Synthetic Lethality, Dosage Rescue
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPB2 YOR151C RNA polymerase II second largest subunit B150 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL10 YLR075W Ribosomal 60S subunit protein L10 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL30 YGL030W Ribosomal 60S subunit protein L30 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
COR1 YBL045C Core subunit of the ubiquinol-cytochrome c reductase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MCM21 YDR318W Component of the kinetochore sub-complex COMA genetic 2 1 2 Negative Genetic, Negative Genetic
KES1 YPL145C Sterol/phosphatidylinositol-4-phosphate (PI(4)P) exchanger physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MES1 YGR264C Methionyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 2 1 2 Negative Genetic, Negative Genetic
FUN12 YAL035W Translation initiation factor eIF5B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPA190 YOR341W RNA polymerase I largest subunit A190 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPA135 YPR010C RNA polymerase I second largest subunit A135 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ILS1 YBL076C Cytoplasmic isoleucine-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC61 YLR378C Conserved ER protein translocation channel genetic 2 1 2 Negative Genetic, Negative Genetic
SOK1 YDR006C Protein of unknown function physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YRB1 YDR002W Ran GTPase binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TOM70 YNL121C Component of the TOM (translocase of outer membrane) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YDJ1 YNL064C Type I HSP40 co-chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TMA19 YKL056C Protein that associates with ribosomes physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPM1 YNL079C Major isoform of tropomyosin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SUB2 YDL084W Component of the TREX complex required for nuclear mRNA export physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF3 YPR163C Translation initiation factor eIF-4B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TSL1 YML100W Large subunit of trehalose 6-phosphate synthase/phosphatase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSZ1 YHR064C Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS1 YBR126C Synthase subunit of trehalose-6-P synthase/phosphatase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ZUO1 YGR285C Ribosome-associated chaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TIF5 YPR041W Translation initiation factor eIF5 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPD3 YAL016W Regulatory subunit A of the heterotrimeric PP2A complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TUB2 YFL037W Beta-tubulin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ZPR1 YGR211W Essential protein with two zinc fingers physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPT16 YGL207W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAM2 YDR502C S-adenosylmethionine synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UGP1 YKL035W UDP-glucose pyrophosphorylase (UGPase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TUB1 YML085C Alpha-tubulin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAC6 YDR129C Fimbrin, actin-bundling protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TUF1 YOR187W Mitochondrial translation elongation factor Tu (EF-Tu) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SUP35 YDR172W Translation termination factor eRF3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS9B YBR189W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UBA1 YKL210W Ubiquitin activating enzyme (E1) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRP2 YER090W Anthranilate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SND3 YBR106W Involved in SRP-independent protein targeting to the ER physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC14 YMR079W Phosphatidylinositol/phosphatidylcholine transfer protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SES1 YDR023W Cytosolic seryl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
STM1 YLR150W Protein required for optimal translation under nutrient stress physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SUI2 YJR007W Alpha subunit of the translation initiation factor eIF2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SPE3 YPR069C Spermidine synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TKL1 YPR074C Transketolase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SAR1 YPL218W ARF family GTPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YDR341C YDR341C Arginyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YLR179C YLR179C Protein of unknown function with similarity to Tfs1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TDH2 YJR009C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YHR020W YHR020W Prolyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRP3 YKL211C Indole-3-glycerol-phosphate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SEC21 YNL287W Gamma subunit of coatomer physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TRP5 YGL026C Tryptophan synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SRV2 YNL138W CAP (cyclase-associated protein) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
TEF2 YBR118W Translational elongation factor EF-1 alpha physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SER3 YER081W 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS4B YHR203C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS14A YCR031C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS13 YDR064W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS22A YJL190C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS26B YER131W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS17B YDR447C Ribosomal protein 51 (rp51) of the small (40s) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS1B YML063W Ribosomal protein of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS27B YHR021C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
YBL005W-A YBL005W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
RPS1A YLR441C Ribosomal protein of the small (40S) subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
SSA3 YBL075C ATPase involved in protein folding and the response to stress physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSA4 YER103W Heat shock protein that is highly induced upon stress physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 2 1 2 Negative Genetic, Negative Genetic
SRP1 YNL189W Karyopherin alpha homolog physical 2 1 2 Reconstituted Complex, Reconstituted Complex
RRP6 YOR001W Nuclear exosome exonuclease component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SHE1 YBL031W Mitotic spindle protein genetic 2 1 2 Negative Genetic, Negative Genetic
UBS1 YBR165W Ubiquitin-conjugating enzyme suppressor that regulates Cdc34p genetic 2 1 2 Negative Genetic, Negative Genetic
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 2 1 2 Negative Genetic, Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 1 2 Negative Genetic, Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 2 1 2 Negative Genetic, Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 2 1 2 Negative Genetic, Negative Genetic
RPS29B YDL061C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 1 2 Negative Genetic, Negative Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 2 1 2 Negative Genetic, Negative Genetic
YBP2 YGL060W Central kinetochore associated protein genetic 2 1 2 Negative Genetic, Negative Genetic
SNF6 YHL025W Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
WSS1 YHR134W SUMO-ligase and SUMO-targeted metalloprotease genetic 2 1 2 Negative Genetic, Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 2 1 2 Negative Genetic, Negative Genetic
VIK1 YPL253C Protein that forms a kinesin-14 heterodimeric motor with Kar3p genetic 2 1 2 Negative Genetic, Negative Genetic
YAR1 YPL239W Nucleocytoplasmic shuttling assembly chaperone genetic 2 1 2 Negative Genetic, Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 2 1 2 Negative Genetic, Negative Genetic
ULA1 YPL003W Protein that activates Rub1p (NEDD8) before neddylation genetic 2 1 2 Negative Genetic, Negative Genetic
HCR1 YLR192C eIF3j component of translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RLI1 YDR091C Essential Fe-S protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IMD3 YLR432W Inosine monophosphate dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PUF6 YDR496C Pumilio-homology domain protein genetic 2 1 2 Negative Genetic, Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HGH1 YGR187C Chaperone protein for translation factor eEF2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADE13 YLR359W Adenylosuccinate lyase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARC35 YNR035C Subunit of the ARP2/3 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARP2 YDL029W Essential component of the Arp2/3 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARP3 YJR065C Essential component of the Arp2/3 complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BAT1 YHR208W Mitochondrial branched-chain amino acid (BCAA) aminotransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BMH2 YDR099W 14-3-3 protein, minor isoform physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CAR1 YPL111W Arginase, catabolizes arginine to ornithine and urea physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CPR1 YDR155C Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CYS4 YGR155W Cystathionine beta-synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG13 YML126C 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity genetic 2 1 2 Negative Genetic, Negative Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLY1 YEL046C Threonine aldolase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HIS4 YCL030C Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CLU1 YMR012W Subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARB1 YER036C ATPase of the ATP-binding cassette (ABC) family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GFA1 YKL104C Glutamine-fructose-6-phosphate amidotransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MCD1 YDL003W Essential alpha-kleisin subunit of the cohesin complex genetic 2 1 2 Negative Genetic, Negative Genetic
GLT1 YDL171C NAD(+)-dependent glutamate synthase (GOGAT) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NMD3 YHR170W Protein involved in nuclear export of the large ribosomal subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LAT1 YNL071W Dihydrolipoamide acetyltransferase component (E2) of the PDC physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PFK1 YGR240C Alpha subunit of heterooctameric phosphofructokinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRO2 YOR323C Gamma-glutamyl phosphate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 2 1 2 Positive Genetic, Positive Genetic
MVD1 YNR043W Mevalonate pyrophosphate decarboxylase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MIR1 YJR077C Mitochondrial phosphate carrier physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CPA2 YJR109C Large subunit of carbamoyl phosphate synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GPM1 YKL152C Tetrameric phosphoglycerate mutase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADE57 YGL234W Bifunctional enzyme of 'de novo' purine nucleotide pathway physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DBP2 YNL112W ATP-dependent RNA helicase of the DEAD-box protein family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PIL1 YGR086C Eisosome core component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PGI1 YBR196C Glycolytic enzyme phosphoglucose isomerase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CCT8 YJL008C Subunit of the cytosolic chaperonin Cct ring complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PFK2 YMR205C Beta subunit of heterooctameric phosphofructokinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 2 Positive Genetic, Positive Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EFB1 YAL003W Translation elongation factor 1 beta physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NEW1 YPL226W Translation termination and ribosome biogenesis factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 2 1 2 Negative Genetic, Negative Genetic
GLN1 YPR035W Glutamine synthetase (GS) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LSP1 YPL004C Eisosome core component physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HYP2 YEL034W Translation elongation factor eIF-5A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADO1 YJR105W Adenosine kinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GPP1 YIL053W Constitutively expressed DL-glycerol-3-phosphate phosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 2 Negative Genetic, Negative Genetic
CPR6 YLR216C Peptidyl-prolyl cis-trans isomerase (cyclophilin) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
AHP1 YLR109W Thiol-specific peroxiredoxin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CMP2 YML057W Calcineurin A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GSP1 YLR293C Ran GTPase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ILV5 YLR355C Acetohydroxyacid reductoisomerase and mtDNA binding protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 2 1 2 Negative Genetic, Negative Genetic
ADK1 YDR226W Adenylate kinase, required for purine metabolism physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
COF1 YLL050C Cofilin, involved in pH-dependent actin filament depolarization physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LIA1 YJR070C Deoxyhypusine hydroxylase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRO3 YER023W Delta 1-pyrroline-5-carboxylate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
APT1 YML022W Adenine phosphoribosyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DLD3 YEL071W 2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ACS2 YLR153C Acetyl-coA synthetase isoform physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FUM1 YPL262W Fumarase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PDC5 YLR134W Minor isoform of pyruvate decarboxylase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MET6 YER091C Cobalamin-independent methionine synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
NPA3 YJR072C Member of the conserved GPN-loop GTPase family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PBA1 YLR199C Protein involved in 20S proteasome assembly genetic 2 1 2 Negative Genetic, Negative Genetic
FAA1 YOR317W Long chain fatty acyl-CoA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
APA1 YCL050C AP4A phosphorylase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CPA1 YOR303W Small subunit of carbamoyl phosphate synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNR1 YER070W Major isoform of large subunit of ribonucleotide-diphosphate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALD5 YER073W Mitochondrial aldehyde dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARG1 YOL058W Arginosuccinate synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRS5 YOL061W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARA1 YBR149W NADP+ dependent arabinose dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
APE2 YKL157W Aminopeptidase yscII physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EXG1 YLR300W Major exo-1,3-beta-glucanase of the cell wall physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PRS1 YKL181W 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DDI1 YER143W Aspartic-type endopeptidase genetic 2 1 2 Negative Genetic, Negative Genetic
ARG3 YJL088W Ornithine carbamoyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GDH1 YOR375C NADP(+)-dependent glutamate dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MSN5 YDR335W Karyopherin genetic 2 1 2 Negative Genetic, Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 2 1 2 Negative Genetic, Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL9A YGL147C Ribosomal 60S subunit protein L9A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ELO3 YLR372W Elongase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HXK2 YGL253W Hexokinase isoenzyme 2 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
KAR3 YPR141C Minus-end-directed microtubule motor genetic 2 1 2 Negative Genetic, Negative Genetic
KAR2 YJL034W ATPase involved in protein import into the ER physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ESC1 YMR219W Protein involved in telomeric silencing physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HCH1 YNL281W Heat shock protein regulator physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
AZF1 YOR113W Zinc-finger transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
RPL1B YGL135W Ribosomal 60S subunit protein L1B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ATP1 YBL099W Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DYS1 YHR068W Deoxyhypusine synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL13A YDL082W Ribosomal 60S subunit protein L13A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL14B YHL001W Ribosomal 60S subunit protein L14B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL7A YGL076C Ribosomal 60S subunit protein L7A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL19B YBL027W Ribosomal 60S subunit protein L19B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL21A YBR191W Ribosomal 60S subunit protein L21A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL27B YDR471W Ribosomal 60S subunit protein L27B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ASN2 YGR124W Asparagine synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARO8 YGL202W Aromatic aminotransferase I physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FUR1 YHR128W Uracil phosphoribosyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CIT1 YNR001C Mitochondrial citrate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG2 YMR202W C-8 sterol isomerase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLK1 YCL040W Glucokinase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARI1 YGL157W NADPH-dependent aldehyde reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARG56 YER069W Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
MSC7 YHR039C Protein of unknown function physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GRE3 YHR104W Aldose reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 2 1 2 Negative Genetic, Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
FRD1 YEL047C Soluble fumarate reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
IDP1 YDL066W Mitochondrial NADP-specific isocitrate dehydrogenase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GLN4 YOR168W Glutamine tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
LAP3 YNL239W Cysteine aminopeptidase with homocysteine-thiolactonase activity physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL20A YMR242C Ribosomal 60S subunit protein L20A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL8B YLL045C Ribosomal 60S subunit protein L8A physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GSH1 YJL101C Gamma glutamylcysteine synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GCS1 YDL226C ADP-ribosylation factor GTPase activating protein (ARF GAP) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ARO2 YGL148W Bifunctional chorismate synthase and flavin reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
GUA1 YMR217W GMP synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PCM1 YEL058W Essential N-acetylglucosamine-phosphate mutase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PAN5 YHR063C 2-dehydropantoate 2-reductase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
CYC1 YJR048W Cytochrome c, isoform 1 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PYP1 YNL010W Sugar alcohol phosphatase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ALO1 YML086C D-Arabinono-1,4-lactone oxidase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
PNC1 YGL037C Nicotinamidase that converts nicotinamide to nicotinic acid physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
OAC1 YKL120W Mitochondrial inner membrane transporter physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG3 YLR056W C-5 sterol desaturase genetic 2 1 2 Positive Genetic, Positive Genetic
MET5 YJR137C Sulfite reductase beta subunit physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HTS1 YPR033C Cytoplasmic and mitochondrial histidine tRNA synthetase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
RPL12B YDR418W Ribosomal 60S subunit protein L12B physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HIS7 YBR248C Imidazole glycerol phosphate synthase physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 2 1 2 Negative Genetic, Negative Genetic
STT3 YGL022W Catalytic subunit of the oligosaccharyltransferase complex of the ER l genetic 2 2 1 Positive Genetic, Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 1 Negative Genetic, Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 2 1 1 Negative Genetic, Negative Genetic
RPN6 YDL097C Essential, non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
RPN3 YER021W Essential non-ATPase regulatory subunit of the 26S proteasome lid genetic 2 1 1 Negative Genetic, Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPN2 YIL075C Subunit of the 26S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
RPT4 YOR259C ATPase of the 19S regulatory particle of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPN7 YPR108W Essential non-ATPase regulatory subunit of the 26S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 2 1 1 Negative Genetic, Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 2 1 1 Negative Genetic, Negative Genetic
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) genetic 2 1 1 Negative Genetic, Negative Genetic
UBI4 YLL039C Ubiquitin genetic 2 1 1 Negative Genetic, Negative Genetic
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 2 1 1 Negative Genetic, Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 2 1 1 Negative Genetic, Negative Genetic
YJU2 YKL095W Essential protein required for pre-mRNA splicing genetic 2 1 1 Negative Genetic, Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 2 1 1 Negative Genetic, Negative Genetic
TAF9 YMR236W Subunit (17 kDa) of TFIID and SAGA complexes genetic 2 1 1 Negative Genetic, Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 2 1 1 Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 2 1 1 Negative Genetic, Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 2 1 1 Negative Genetic, Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 2 1 1 Negative Genetic, Negative Genetic
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 2 1 1 Negative Genetic, Negative Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
RPS28B YLR264W Protein component of the small (40S) ribosomal subunit genetic 2 1 1 Negative Genetic, Negative Genetic
YML108W YML108W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 2 1 1 Negative Genetic, Negative Genetic
TFB5 YDR079C-A Component of RNA polymerase II general transcription factor TFIIH genetic 2 1 1 Synthetic Rescue, Synthetic Rescue
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 1 Synthetic Haploinsufficiency, Synthetic Haploinsufficiency
PRE1 YER012W Beta 4 subunit of the 20S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
PRE5 YMR314W Alpha 6 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 2 1 1 Positive Genetic, Positive Genetic
PRE8 YML092C Alpha 2 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
BCP1 YDR361C Essential nuclear chaperone for ribosomal protein Rpl23p genetic 2 1 1 Negative Genetic, Negative Genetic
RNT1 YMR239C Nuclear dsRNA-specific ribonuclease (RNase III) genetic 2 1 1 Negative Genetic, Negative Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 1 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 2 1 1 Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 2 1 1 Positive Genetic, Positive Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 2 1 1 Negative Genetic, Negative Genetic
PRE4 YFR050C Beta 7 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
DAM1 YGR113W Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 1 1 Negative Genetic, Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 2 1 1 Negative Genetic, Negative Genetic
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 2 1 1 Negative Genetic, Negative Genetic
CDC53 YDL132W Cullin genetic 2 1 1 Negative Genetic, Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 2 1 1 Negative Genetic, Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 2 1 1 Negative Genetic, Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex genetic 2 1 1 Negative Genetic, Negative Genetic
ASK1 YKL052C Essential subunit of the Dam1 complex (aka DASH complex) genetic 2 1 1 Negative Genetic, Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
CDC27 YBL084C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 1 1 Negative Genetic, Negative Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 2 1 1 Negative Genetic, Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 2 1 1 Negative Genetic, Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 1 1 Negative Genetic, Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 2 1 1 Negative Genetic, Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 2 1 1 Negative Genetic, Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 2 1 1 Negative Genetic, Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 2 1 1 Negative Genetic, Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
POC4 YPL144W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 1 Negative Genetic, Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 2 1 1 Negative Genetic, Negative Genetic
RPL17B YJL177W Ribosomal 60S subunit protein L17B genetic 2 1 1 Negative Genetic, Negative Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 2 1 1 Negative Genetic, Negative Genetic
CHM7 YJL049W Yeast homolog of human CHMP7, localizes to the endoplasmic reticulum genetic 2 1 1 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 1 Negative Genetic, Negative Genetic
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC40 YDR364C Pre-mRNA splicing factor genetic 1 1 1 Negative Genetic
CHL4 YDR254W Outer kinetochore protein required for chromosome stability genetic 1 1 1 Negative Genetic
CTF19 YPL018W Outer kinetochore protein, needed for accurate chromosome segregation genetic 1 1 1 Negative Genetic
LEO1 YOR123C Component of the Paf1 complex genetic 1 1 1 Positive Genetic
CBF5 YLR175W Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs physical 1 1 1 Affinity Capture-MS
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Positive Genetic
CKA2 YOR061W Alpha' catalytic subunit of casein kinase 2 (CK2) physical 1 1 1 Affinity Capture-MS
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Positive Genetic
IKI3 YLR384C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) physical 1 1 1 Affinity Capture-MS
HSP60 YLR259C Tetradecameric mitochondrial chaperonin physical 1 1 1 Affinity Capture-MS
NIP7 YPL211W Nucleolar protein required for 60S ribosome subunit biogenesis physical 1 1 1 Affinity Capture-MS
NOG1 YPL093W Putative GTPase physical 1 1 1 Affinity Capture-MS
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
RPF2 YKR081C Essential protein involved in rRNA maturation and ribosomal assembly genetic 1 1 1 Negative Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Negative Genetic
RPL16A YIL133C Ribosomal 60S subunit protein L16A physical 1 1 1 Affinity Capture-MS
GCD6 YDR211W Catalytic epsilon subunit of the translation initiation factor eIF2B physical 1 1 1 Affinity Capture-MS
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
EMW1 YNL313C Essential conserved protein with a role in cell wall integrity physical 1 1 1 Affinity Capture-MS
CDC42 YLR229C Small rho-like GTPase physical 1 1 1 Affinity Capture-MS
NUG1 YER006W GTPase that associates with nuclear 60S pre-ribosomes physical 1 1 1 Affinity Capture-MS
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling genetic 1 1 1 Negative Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 Affinity Capture-MS
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Negative Genetic
DBP3 YGL078C RNA-Dependent ATPase, member of DExD/H-box family physical 1 1 1 Affinity Capture-MS
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
NAT3 YPR131C Catalytic subunit of the NatB N-terminal acetyltransferase physical 1 1 1 Affinity Capture-MS
RCK2 YLR248W Protein kinase involved in response to oxidative and osmotic stress physical 1 1 1 Affinity Capture-MS
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
NOP1 YDL014W Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus genetic 1 1 1 Negative Genetic
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein physical 1 1 1 Affinity Capture-MS
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
RPC40 YPR110C RNA polymerase subunit AC40 physical 1 1 1 Affinity Capture-MS
RPB5 YBR154C RNA polymerase subunit ABC27 physical 1 1 1 Affinity Capture-MS
RET1 YOR207C Second-largest subunit of RNA polymerase III physical 1 1 1 Affinity Capture-MS
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
RPC34 YNR003C RNA polymerase III subunit C34 genetic 1 1 1 Negative Genetic
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Positive Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit physical 1 1 1 Affinity Capture-MS
NAP1 YKR048C Histone chaperone and assembly chaperone for Rps6a/b physical 1 1 1 Affinity Capture-MS
RPN1 YHR027C Non-ATPase base subunit of the 19S RP of the 26S proteasome genetic 1 1 1 Negative Genetic
UBP6 YFR010W Ubiquitin-specific protease genetic 1 1 1 Synthetic Lethality
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-Western
SPG5 YMR191W Protein required for proteasome assembly during quiescence physical 1 1 1 Affinity Capture-MS
RRS1 YOR294W Essential protein that binds ribosomal protein L11 physical 1 1 1 Affinity Capture-MS
SQT1 YIR012W Specific assembly chaperone for ribosomal protein Rpl10p physical 1 1 1 Affinity Capture-MS
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TAE1 YBR261C AdoMet-dependent proline methyltransferase physical 1 1 1 Affinity Capture-MS
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination genetic 1 1 1 Negative Genetic
SAC6 YDR129C Fimbrin, actin-bundling protein genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk physical 1 1 1 Affinity Capture-MS
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
SFB3 YHR098C Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase physical 1 1 1 Affinity Capture-MS
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex physical 1 1 1 Affinity Capture-MS
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
URA2 YJL130C Bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase physical 1 1 1 Affinity Capture-MS
RPS0A YGR214W Ribosomal 40S subunit protein S0A genetic 1 1 1 Negative Genetic
YMC1 YPR058W Secondary mitochondrial inner membrane glycine transporter physical 1 1 1 Affinity Capture-MS
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane physical 1 1 1 Affinity Capture-MS
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 1 1 1 Negative Genetic
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering physical 1 1 1 Affinity Capture-MS
SHB17 YKR043C Sedoheptulose bisphosphatase involved in riboneogenesis physical 1 1 1 Affinity Capture-MS
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SHM2 YLR058C Cytosolic serine hydroxymethyltransferase physical 1 1 1 Affinity Capture-MS
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPS6B YBR181C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor physical 1 1 1 Affinity Capture-MS
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 1 1 1 Affinity Capture-MS
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS23A YGR118W Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RRP43 YCR035C Exosome non-catalytic core component physical 1 1 1 Affinity Capture-MS
RSC8 YFR037C Component of the RSC chromatin remodeling complex physical 1 1 1 Affinity Capture-MS
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Affinity Capture-MS
RTG2 YGL252C Sensor of mitochondrial dysfunction physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein physical 1 1 1 Affinity Capture-MS
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein physical 1 1 1 Affinity Capture-MS
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 Affinity Capture-MS
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Affinity Capture-MS
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC17 YBL050W Alpha-SNAP cochaperone physical 1 1 1 Affinity Capture-MS
SER33 YIL074C 3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase physical 1 1 1 Affinity Capture-MS
SFA1 YDL168W Bifunctional alcohol dehydrogenase and formaldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p physical 1 1 1 Affinity Capture-MS
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
SKP1 YDR328C Evolutionarily conserved kinetochore protein physical 1 1 1 Affinity Capture-MS
SLT2 YHR030C Serine/threonine MAP kinase physical 1 1 1 Affinity Capture-MS
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
SRP54 YPR088C Signal recognition particle (SRP) subunit (homolog of mammalian SRP54) physical 1 1 1 Affinity Capture-MS
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
SSD1 YDR293C Translational repressor physical 1 1 1 Affinity Capture-MS
SSS1 YDR086C Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) physical 1 1 1 Affinity Capture-MS
SST2 YLR452C GTPase-activating protein for Gpa1p physical 1 1 1 Affinity Capture-MS
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Positive Genetic
SUA7 YPR086W Transcription factor TFIIB physical 1 1 1 Affinity Capture-MS
SUI3 YPL237W Beta subunit of the translation initiation factor eIF2 physical 1 1 1 Affinity Capture-MS
SVL3 YPL032C Protein of unknown function physical 1 1 1 Affinity Capture-MS
SXM1 YDR395W Nuclear transport factor (karyopherin) physical 1 1 1 Affinity Capture-MS
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes physical 1 1 1 Affinity Capture-MS
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit physical 1 1 1 Affinity Capture-MS
THR1 YHR025W Homoserine kinase physical 1 1 1 Affinity Capture-MS
THR4 YCR053W Threonine synthase physical 1 1 1 Affinity Capture-MS
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein physical 1 1 1 Affinity Capture-MS
TMA20 YER007C-A Protein of unknown function that associates with ribosomes physical 1 1 1 Affinity Capture-MS
TMA22 YJR014W Protein of unknown function physical 1 1 1 Affinity Capture-MS
TPA1 YER049W Prolyl hydroxylase physical 1 1 1 Affinity Capture-MS
TRM8 YDL201W Catalytic subunit of a tRNA methyltransferase complex physical 1 1 1 Affinity Capture-MS
TRR1 YDR353W Cytoplasmic thioredoxin reductase physical 1 1 1 Affinity Capture-MS
TRX1 YLR043C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 Affinity Capture-MS
TYS1 YGR185C Cytoplasmic tyrosyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation physical 1 1 1 Affinity Capture-MS
UBC4 YBR082C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
UBP14 YBR058C Ubiquitin-specific protease physical 1 1 1 Affinity Capture-MS
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase physical 1 1 1 Affinity Capture-MS
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 Affinity Capture-MS
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-MS
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Affinity Capture-MS
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Phenotypic Enhancement
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor physical 1 1 1 Affinity Capture-MS
XPT1 YJR133W Xanthine-guanine phosphoribosyl transferase physical 1 1 1 Affinity Capture-MS
YAR010C YAR010C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YBL005W-B YBL005W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YBP1 YBR216C Protein involved in cellular response to oxidative stress physical 1 1 1 Affinity Capture-MS
YBR012W-A YBR012W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YBR012W-B YBR012W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YBR053C YBR053C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YCP4 YCR004C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YCR051W YCR051W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YDL124W YDL124W NADPH-dependent alpha-keto amide reductase physical 1 1 1 Affinity Capture-MS
YDR098C-A YDR098C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YDR170W-A YDR170W-A Retrotransposon TYA Gag gene physical 1 1 1 Affinity Capture-MS
YDR210C-C YDR210C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YDR210C-D YDR210C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR261C-C YDR261C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YDR316W-A YDR316W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YDR316W-B YDR316W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YDR365W-A YDR365W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YER137C-A YER137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YER138C YER138C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YER159C-A YER159C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YER160C YER160C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YET3 YDL072C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YGL039W YGL039W Aldehyde reductase physical 1 1 1 Affinity Capture-MS
YGR027W-A YGR027W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YGR027W-B YGR027W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YGR038C-A YGR038C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YGR054W YGR054W Eukaryotic initiation factor eIF2A physical 1 1 1 Affinity Capture-MS
YGR109W-A YGR109W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YGR161C-C YGR161C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YGR161C-D YGR161C-D Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YHI9 YHR029C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YHM2 YMR241W Citrate and oxoglutarate carrier protein physical 1 1 1 Affinity Capture-MS
YHR214C-C YHR214C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YIL108W YIL108W Putative metalloendopeptidase physical 1 1 1 Affinity Capture-MS
YIP3 YNL044W Protein localized to COPII vesicles physical 1 1 1 Affinity Capture-MS
YJR026W YJR026W Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YJR028W YJR028W Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YJR029W YJR029W Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YKR018C YKR018C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity physical 1 1 1 Affinity Capture-MS
YLR035C-A YLR035C-A Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YLR157C-A YLR157C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YLR225C YLR225C Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
YLR227W-A YLR227W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YLR256W-A YLR256W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YML040W YML040W Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YML045W-A YML045W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YMR027W YMR027W A metal-dependent phosphatase, part of the DUF89 protein family physical 1 1 1 Affinity Capture-MS
YMR045C YMR045C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YMR046C YMR046C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YMR050C YMR050C Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YMR051C YMR051C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YMR315W YMR315W Protein with NADP(H) oxidoreductase activity physical 1 1 1 Affinity Capture-MS
YNL054W-A YNL054W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YNL054W-B YNL054W-B TyB Gag-Pol protein physical 1 1 1 Affinity Capture-MS
YNL108C YNL108C Protein phosphatase physical 1 1 1 Affinity Capture-MS
YNL208W YNL208W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YNL284C-A YNL284C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YNL284C-B YNL284C-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YOL103W-A YOL103W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YOL103W-B YOL103W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
YOP1 YPR028W Reticulon-interacting protein physical 1 1 1 Affinity Capture-MS
YOR142W-A YOR142W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YOR142W-B YOR142W-B Retrotransposon TYA Gag and TYB Pol genes physical 1 1 1 Affinity Capture-MS
TUM1 YOR251C Rhodanese domain sulfur transferase physical 1 1 1 Affinity Capture-MS
YOR283W YOR283W Phosphatase with a broad substrate specificity physical 1 1 1 Affinity Capture-MS
YPK1 YKL126W S/T protein kinase physical 1 1 1 Affinity Capture-MS
YPL088W YPL088W Putative aryl alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
YPL225W YPL225W Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPL257W-A YPL257W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPR1 YDR368W NADPH-dependent aldo-keto reductase physical 1 1 1 Affinity Capture-MS
YPR137C-A YPR137C-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPR148C YPR148C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YPR158C-C YPR158C-C Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPR158W-A YPR158W-A Retrotransposon TYA Gag gene co-transcribed with TYB Pol physical 1 1 1 Affinity Capture-MS
YPT1 YFL038C Rab family GTPase physical 1 1 1 Affinity Capture-MS
YPT31 YER031C Rab family GTPase physical 1 1 1 Affinity Capture-MS
YRB2 YIL063C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity physical 1 1 1 Affinity Capture-MS
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Positive Genetic
SRP1 YNL189W Karyopherin alpha homolog genetic 1 1 1 Dosage Rescue
UFO1 YML088W F-box receptor protein physical 1 1 1 Affinity Capture-Western
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SIZ1 YDR409W SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
ULP2 YIL031W Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins physical 1 1 1 Affinity Capture-MS
RPS11A YDR025W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
TIF1 YKR059W Translation initiation factor eIF4A physical 1 1 1 Affinity Capture-MS
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RUB1 YDR139C Ubiquitin-like protein with similarity to mammalian NEDD8 physical 1 1 1 Biochemical Activity
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TFC6 YDR362C Subunit of RNA polymerase III transcription initiation factor complex physical 1 1 1 Affinity Capture-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) physical 1 1 1 Proximity Label-MS
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
RPP2B YDR382W Ribosomal protein P2 beta genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Positive Genetic
SKI7 YOR076C GTP-binding protein that couples the Ski complex and exosome genetic 1 1 1 Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Positive Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Positive Genetic
RRP1 YDR087C Essential evolutionarily conserved nucleolar protein genetic 1 1 1 Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 1 1 1 Positive Genetic
YCG1 YDR325W Subunit of the condensin complex genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
SOG2 YOR353C Key component of the RAM signaling network genetic 1 1 1 Positive Genetic
YTH1 YPR107C Essential RNA-binding component of cleavage and polyadenylation factor genetic 1 1 1 Positive Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Positive Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
SIF2 YBR103W WD40 repeat-containing subunit of Set3C histone deacetylase complex genetic 1 1 1 Positive Genetic
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Positive Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Positive Genetic
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Positive Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Positive Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 1 1 1 Positive Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 1 1 1 Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RRP42 YDL111C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
UBC1 YDR177W Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
SMT3 YDR510W Ubiquitin-like protein of the SUMO family genetic 1 1 1 Negative Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Negative Genetic
SPC19 YDR201W Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SPC97 YHR172W Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex genetic 1 1 1 Negative Genetic
RPO31 YOR116C RNA polymerase III largest subunit C160 genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
SPC42 YKL042W Central plaque component of spindle pole body (SPB) genetic 1 1 1 Negative Genetic
SDO1 YLR022C Guanine nucleotide exchange factor (GEF) for Ria1p genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Negative Genetic
YCS4 YLR272C Subunit of the condensin complex genetic 1 1 1 Negative Genetic
TAP42 YMR028W Essential protein involved in the TOR signaling pathway genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SEC16 YPL085W COPII vesicle coat protein required for ER transport vesicle budding genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Negative Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 1 1 1 Negative Genetic
RPS28A YOR167C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RPS6A YPL090C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SPO11 YHL022C Meiosis-specific protein required for meiotic recombination genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
YCL068C YCL068C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SYO1 YDL063C Transport adaptor or symportin genetic 1 1 1 Negative Genetic
RXT3 YDL076C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
YOS9 YDR057W ER quality-control lectin genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Negative Genetic
SPT2 YER161C Protein involved in negative regulation of transcription genetic 1 1 1 Negative Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Negative Genetic
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
YGR122W YGR122W Protein that may be involved in pH regulation genetic 1 1 1 Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 1 1 1 Negative Genetic
YHL008C YHL008C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SET1 YHR119W Histone methyltransferase, subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
RPS4A YJR145C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YLR154C-H YLR154C-H Putative protein of unknown function genetic 1 1 1 Negative Genetic
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Negative Genetic
RPS29A YLR388W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
TRM9 YML014W tRNA methyltransferase genetic 1 1 1 Negative Genetic
YMR001C-A YMR001C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YMR175W-A YMR175W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
YNL067W-B YNL067W-B Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGP1 YNL160W Cell wall-related secretory glycoprotein genetic 1 1 1 Negative Genetic
YPT11 YNL304W Rab GTPase genetic 1 1 1 Negative Genetic
RTG1 YOL067C Transcription factor (bHLH) involved in interorganelle communication genetic 1 1 1 Negative Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RTS1 YOR014W B-type regulatory subunit of protein phosphatase 2A (PP2A) genetic 1 1 1 Negative Genetic
UAF30 YOR295W Subunit of UAF (upstream activation factor) complex genetic 1 1 1 Negative Genetic
YTA6 YPL074W Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family genetic 1 1 1 Negative Genetic
YPL108W YPL108W Cytoplasmic protein of unknown function genetic 1 1 1 Negative Genetic
SDD4 YPR022C Putative transcription factor, as suggested by computational analysis genetic 1 1 1 Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 1 1 1 Negative Genetic
PRT1 YOR361C eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) physical 1 1 1 Affinity Capture-MS
RPG1 YBR079C eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
GCD1 YOR260W Gamma subunit of the translation initiation factor eIF2B genetic 1 1 1 Positive Genetic
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
IMD2 YHR216W Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
RBG2 YGR173W Protein with a role in translation physical 1 1 1 Affinity Capture-MS
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) physical 1 1 1 Affinity Capture-MS
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Positive Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Negative Genetic
LSG1 YGL099W Putative GTPase involved in 60S ribosomal subunit biogenesis physical 1 1 1 Affinity Capture-MS
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 physical 1 1 1 Affinity Capture-MS
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily physical 1 1 1 Affinity Capture-MS
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
OLA1 YBR025C P-loop ATPase with similarity to human OLA1 and bacterial YchF genetic 1 1 1 Negative Genetic
ADE4 YMR300C Phosphoribosylpyrophosphate amidotransferase (PRPPAT) physical 1 1 1 Affinity Capture-MS
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
APC2 YLR127C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ARC40 YBR234C Subunit of the ARP2/3 complex physical 1 1 1 Affinity Capture-MS
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 1 1 1 Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 1 1 1 Negative Genetic
CAF130 YGR134W Subunit of the CCR4-NOT transcriptional regulatory complex genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Dosage Rescue
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit physical 1 1 1 Affinity Capture-MS
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 1 1 1 Affinity Capture-MS
ERG26 YGL001C C-3 sterol dehydrogenase physical 1 1 1 Affinity Capture-MS
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
NOG2 YNR053C Putative GTPase physical 1 1 1 Affinity Capture-MS
NOG2 YNR053C Putative GTPase genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CHC1 YGL206C Clathrin heavy chain physical 1 1 1 Affinity Capture-MS
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex physical 1 1 1 Affinity Capture-MS
DCP2 YNL118C Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation physical 1 1 1 Affinity Capture-MS
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites physical 1 1 1 Affinity Capture-MS
ELP2 YGR200C Subunit of Elongator complex physical 1 1 1 Affinity Capture-MS
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
EMG1 YLR186W Methyltransferase for rRNA genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Positive Genetic
FPR1 YNL135C Peptidyl-prolyl cis-trans isomerase (PPIase) genetic 1 1 1 Negative Genetic
GCN2 YDR283C Protein kinase genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor physical 1 1 1 Affinity Capture-MS
HRP1 YOL123W Subunit of cleavage factor I physical 1 1 1 Affinity Capture-MS
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
KRR1 YCL059C Nucleolar protein required for rRNA synthesis and ribosomal assembly genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance genetic 1 1 1 Negative Genetic
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
MRP7 YNL005C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRM1 YOR201C Ribose methyltransferase genetic 1 1 1 Positive Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 1 1 1 Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
INO80 YGL150C Nucleosome spacing factor physical 1 1 1 Affinity Capture-MS
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NOT3 YIL038C Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Negative Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Positive Genetic
PAP1 YKR002W Poly(A) polymerase physical 1 1 1 Affinity Capture-MS
HMO1 YDR174W Chromatin associated high mobility group (HMG) family member genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex physical 1 1 1 Affinity Capture-MS
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase physical 1 1 1 Affinity Capture-MS
BLM10 YFL007W Proteasome activator physical 1 1 1 Affinity Capture-MS
HTA1 YDR225W Histone H2A genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
PSE1 YMR308C Karyopherin/importin that interacts with the nuclear pore complex physical 1 1 1 Affinity Capture-MS
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PAA1 YDR071C Polyamine acetyltransferase physical 1 1 1 Affinity Capture-MS
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
GCN20 YFR009W Positive regulator of the Gcn2p kinase activity physical 1 1 1 Affinity Capture-MS
REF2 YDR195W RNA-binding protein genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RFC3 YNL290W Subunit of heteropentameric Replication factor C (RF-C) physical 1 1 1 Affinity Capture-MS
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
RPL23A YBL087C Ribosomal 60S subunit protein L23A physical 1 1 1 Affinity Capture-MS
RPL23A YBL087C Ribosomal 60S subunit protein L23A genetic 1 1 1 Negative Genetic
ADE3 YGR204W Cytoplasmic trifunctional enzyme physical 1 1 1 Affinity Capture-MS
CSN9 YDR179C Subunit of the Cop9 signalosome genetic 1 1 1 Synthetic Growth Defect
PCI8 YIL071C Possible shared subunit of Cop9 signalosome (CSN) and eIF3 genetic 1 1 1 Synthetic Growth Defect
CSI1 YMR025W Subunit of the Cop9 signalosome genetic 1 1 1 Synthetic Growth Defect
NUM1 YDR150W Protein required for nuclear migration genetic 1 1 1 Positive Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
CSE1 YGL238W Nuclear envelope protein that acts as a recycling factor genetic 1 1 1 Negative Genetic
DUG1 YFR044C Cys-Gly metallo-di-peptidase physical 1 1 1 Affinity Capture-MS
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain physical 1 1 1 Affinity Capture-MS
REG1 YDR028C Regulatory subunit of type 1 protein phosphatase Glc7p physical 1 1 1 Affinity Capture-MS
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) physical 1 1 1 Affinity Capture-MS
BRO1 YPL084W Cytoplasmic class E vacuolar protein sorting (VPS) factor genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 1 1 1 Negative Genetic
BNA3 YJL060W Kynurenine aminotransferase physical 1 1 1 Affinity Capture-MS
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-MS
FAR11 YNL127W Protein involved in recovery from cell cycle arrest genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization physical 1 1 1 Affinity Capture-MS
CAR2 YLR438W L-ornithine transaminase (OTAse) physical 1 1 1 Affinity Capture-MS
ACO1 YLR304C Aconitase physical 1 1 1 Affinity Capture-MS
BBC1 YJL020C Protein possibly involved in assembly of actin patches physical 1 1 1 Affinity Capture-MS
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Affinity Capture-MS
NGL2 YMR285C Protein involved in 5.8S rRNA processing physical 1 1 1 Affinity Capture-MS
PYC1 YGL062W Pyruvate carboxylase isoform genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Affinity Capture-MS
RNR2 YJL026W Ribonucleotide-diphosphate reductase (RNR), small subunit physical 1 1 1 Affinity Capture-MS
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator physical 1 1 1 Affinity Capture-MS
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 Affinity Capture-MS
GDE1 YPL110C Glycerophosphocholine (GroPCho) phosphodiesterase physical 1 1 1 Affinity Capture-MS
ARO4 YBR249C 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Positive Genetic
PRO1 YDR300C Gamma-glutamyl kinase physical 1 1 1 Affinity Capture-MS
AAT2 YLR027C Cytosolic aspartate aminotransferase involved in nitrogen metabolism physical 1 1 1 Affinity Capture-MS
GET2 YER083C Subunit of the GET complex genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Positive Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex physical 1 1 1 Affinity Capture-MS
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) physical 1 1 1 Affinity Capture-MS
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
PRS3 YHL011C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-MS
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor physical 1 1 1 Affinity Capture-MS
CYC8 YBR112C General transcriptional co-repressor genetic 1 1 1 Negative Genetic
MAE1 YKL029C Mitochondrial malic enzyme physical 1 1 1 Affinity Capture-MS
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
ILV3 YJR016C Dihydroxyacid dehydratase physical 1 1 1 Affinity Capture-MS
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins physical 1 1 1 Affinity Capture-MS
RHO1 YPR165W GTP-binding protein of the rho subfamily of Ras-like proteins genetic 1 1 1 Negative Genetic
AIP1 YMR092C Actin cortical patch component physical 1 1 1 Affinity Capture-MS
PDS1 YDR113C Securin physical 1 1 1 Biochemical Activity
ERG1 YGR175C Squalene epoxidase physical 1 1 1 Affinity Capture-MS
HRT3 YLR097C Putative SCF-ubiquitin ligase F-box protein physical 1 1 1 Affinity Capture-MS
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis physical 1 1 1 Affinity Capture-MS
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III physical 1 1 1 Affinity Capture-MS
IMD4 YML056C Inosine monophosphate dehydrogenase physical 1 1 1 Affinity Capture-MS
APE1 YKL103C Vacuolar aminopeptidase yscI physical 1 1 1 Affinity Capture-MS
DSK2 YMR276W Nuclear-enriched ubiquitin-like polyubiquitin-binding protein genetic 1 1 1 Synthetic Rescue
HMF1 YER057C Member of the p14.5 protein family physical 1 1 1 Affinity Capture-MS
HSL7 YBR133C Protein arginine N-methyltransferase genetic 1 1 1 Negative Genetic
GRS1 YBR121C Cytoplasmic and mitochondrial glycyl-tRNA synthase genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) physical 1 1 1 Affinity Capture-MS
CDC37 YDR168W Essential Hsp90p co-chaperone physical 1 1 1 Affinity Capture-MS
CDC37 YDR168W Essential Hsp90p co-chaperone genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation physical 1 1 1 Affinity Capture-MS
GPN3 YLR243W Putative GTPase with a role in biogenesis of RNA pol II and polIII physical 1 1 1 Affinity Capture-MS
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) physical 1 1 1 Affinity Capture-MS
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
HUL5 YGL141W Multiubiquitin chain assembly factor (E4) physical 1 1 1 Affinity Capture-Western
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 1 1 1 Affinity Capture-MS
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Negative Genetic
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-MS
ISU1 YPL135W Conserved protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein physical 1 1 1 PCA
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Positive Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p physical 1 1 1 Affinity Capture-MS
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 1 1 1 Negative Genetic
RCN2 YOR220W Protein of unknown function physical 1 1 1 Affinity Capture-MS
PGM1 YKL127W Phosphoglucomutase, minor isoform physical 1 1 1 Affinity Capture-MS
ILV2 YMR108W Acetolactate synthase physical 1 1 1 Affinity Capture-MS
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase physical 1 1 1 Affinity Capture-MS
RGI1 YER067W Protein involved in energy metabolism under respiratory conditions physical 1 1 1 Affinity Capture-MS
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Negative Genetic
ARF2 YDL137W ADP-ribosylation factor physical 1 1 1 Affinity Capture-MS
MAP2 YBL091C Methionine aminopeptidase genetic 1 1 1 Negative Genetic
MCK1 YNL307C Dual-specificity ser/thr and tyrosine protein kinase genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
FUB1 YCR076C Proteasome-binding protein physical 1 1 1 Affinity Capture-Western
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response physical 1 1 1 Affinity Capture-MS
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating physical 1 1 1 Affinity Capture-MS
LEM3 YNL323W Membrane protein of the plasma membrane and ER genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein physical 1 1 1 Affinity Capture-MS
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p physical 1 1 1 Affinity Capture-MS
ADH6 YMR318C NADPH-dependent medium chain alcohol dehydrogenase physical 1 1 1 Affinity Capture-MS
PMI40 YER003C Mannose-6-phosphate isomerase physical 1 1 1 Affinity Capture-MS
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase physical 1 1 1 Affinity Capture-Western
MGT1 YDL200C DNA repair methyltransferase (6-O-methylguanine-DNA methylase) genetic 1 1 1 Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) physical 1 1 1 Affinity Capture-MS
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair physical 1 1 1 Affinity Capture-MS
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) physical 1 1 1 Affinity Capture-MS
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
CUE5 YOR042W Ubiquitin-binding protein physical 1 1 1 Affinity Capture-MS
DAD2 YKR083C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
ECM11 YDR446W Meiosis-specific protein genetic 1 1 1 Negative Genetic
DID4 YKL002W Class E Vps protein of the ESCRT-III complex genetic 1 1 1 Negative Genetic
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 Affinity Capture-MS
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
FIG1 YBR040W Integral membrane protein required for efficient mating physical 1 1 1 Affinity Capture-MS
LST7 YGR057C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes physical 1 1 1 Reconstituted Complex
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Positive Genetic
PEX21 YGR239C Peroxin required for peroxisomal matrix protein targeting genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Negative Genetic
PRM3 YPL192C Protein required for nuclear envelope fusion during karyogamy physical 1 1 1 Affinity Capture-MS
CHA4 YLR098C DNA binding transcriptional activator genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
MET14 YKL001C Adenylylsulfate kinase physical 1 1 1 Affinity Capture-MS
OCA2 YNL056W Protein of unknown function genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Positive Genetic
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CWC15 YDR163W Non-essential protein involved in pre-mRNA splicing genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
IKI1 YHR187W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins genetic 1 1 1 Negative Genetic
NFI1 YOR156C SUMO E3 ligase physical 1 1 1 Affinity Capture-MS
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Positive Genetic
CET1 YPL228W RNA 5'-triphosphatase involved in mRNA 5' capping genetic 1 1 1 Positive Genetic
MSN2 YMR037C Stress-responsive transcriptional activator physical 1 1 1 Affinity Capture-MS
ARP5 YNL059C Nuclear actin-related protein involved in chromatin remodeling physical 1 1 1 Affinity Capture-MS
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-MS
BRN1 YBL097W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Negative Genetic
MYO5 YMR109W One of two type I myosin motors physical 1 1 1 Affinity Capture-MS
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Positive Genetic
PNG1 YPL096W Conserved peptide N-glycanase physical 1 1 1 Affinity Capture-MS
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 1 1 1 Negative Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
DPH2 YKL191W Protein required for synthesis of diphthamide physical 1 1 1 Affinity Capture-MS
KTI11 YBL071W-A Zn-ribbon protein that co-purifies with Dph1 and Dph2 genetic 1 1 1 Negative Genetic
MBF1 YOR298C-A Transcriptional coactivator physical 1 1 1 Affinity Capture-MS
MOB1 YIL106W Component of the mitotic exit network physical 1 1 1 Proximity Label-MS
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
NUP170 YBL079W Subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
MPT5 YGL178W mRNA-binding protein of the PUF family genetic 1 1 1 Negative Genetic
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity physical 1 1 1 Affinity Capture-MS
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Positive Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase physical 1 1 1 Affinity Capture-MS
HMT1 YBR034C Nuclear SAM-dependent mono- and asymmetric methyltransferase physical 1 1 1 Affinity Capture-MS
PRP16 YKR086W DEAH-box RNA helicase genetic 1 1 1 Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p physical 1 1 1 Affinity Capture-MS
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 1 1 1 Negative Genetic
RGD2 YFL047W GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p physical 1 1 1 Affinity Capture-MS
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase physical 1 1 1 Affinity Capture-MS
NIP100 YPL174C Large subunit of the dynactin complex genetic 1 1 1 Positive Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Negative Genetic
NCP1 YHR042W NADP-cytochrome P450 reductase physical 1 1 1 Affinity Capture-MS
RPL25 YOL127W Ribosomal 60S subunit protein L25 physical 1 1 1 Affinity Capture-MS
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane physical 1 1 1 Affinity Capture-MS
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
ENT5 YDR153C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
ATG10 YLL042C Conserved E2-like conjugating enzyme genetic 1 1 1 Negative Genetic
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Positive Genetic
HBT1 YDL223C Shmoo tip protein, substrate of Hub1p ubiquitin-like protein physical 1 1 1 Affinity Capture-MS
ERV14 YGL054C COPII-coated vesicle protein physical 1 1 1 Affinity Capture-MS
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Positive Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
EFT1 YOR133W Elongation factor 2 (EF-2), also encoded by EFT2 physical 1 1 1 Affinity Capture-MS
RPL18B YNL301C Ribosomal 60S subunit protein L18B physical 1 1 1 Affinity Capture-MS
PER33 YLR064W Protein that localizes to the endoplasmic reticulum genetic 1 1 1 Negative Genetic
RPL14B YHL001W Ribosomal 60S subunit protein L14B genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
RPL15A YLR029C Ribosomal 60S subunit protein L15A physical 1 1 1 Affinity Capture-MS
RPL15A YLR029C Ribosomal 60S subunit protein L15A genetic 1 1 1 Negative Genetic
ERG5 YMR015C C-22 sterol desaturase physical 1 1 1 Affinity Capture-MS
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
ILV6 YCL009C Regulatory subunit of acetolactate synthase physical 1 1 1 Affinity Capture-MS
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) physical 1 1 1 Affinity Capture-MS
MEU1 YLR017W Methylthioadenosine phosphorylase (MTAP) genetic 1 1 1 Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis physical 1 1 1 Affinity Capture-MS
RPL16B YNL069C Ribosomal 60S subunit protein L16B physical 1 1 1 Affinity Capture-MS
HSP26 YBR072W Small heat shock protein (sHSP) with chaperone activity physical 1 1 1 Affinity Capture-MS
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 1 1 1 Positive Genetic
FRA1 YLL029W Protein involved in negative regulation of iron regulon transcription physical 1 1 1 Affinity Capture-MS
ASG7 YJL170C Protein that regulates signaling from G protein beta subunit Ste4p physical 1 1 1 Affinity Capture-MS
CAN1 YEL063C Plasma membrane arginine permease physical 1 1 1 Affinity Capture-Western
MXR1 YER042W Methionine-S-sulfoxide reductase physical 1 1 1 Affinity Capture-MS
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Negative Genetic
KRE2 YDR483W Alpha1,2-mannosyltransferase of the Golgi physical 1 1 1 Affinity Capture-MS
MRH1 YDR033W Protein that localizes primarily to the plasma membrane physical 1 1 1 Affinity Capture-MS
NCE102 YPR149W Protein of unknown function physical 1 1 1 Affinity Capture-MS
MET17 YLR303W O-acetyl homoserine-O-acetyl serine sulfhydrylase physical 1 1 1 Affinity Capture-MS
BDH1 YAL060W NAD-dependent (R,R)-butanediol dehydrogenase physical 1 1 1 Affinity Capture-MS
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization physical 1 1 1 Affinity Capture-MS
MAP1 YLR244C Methionine aminopeptidase physical 1 1 1 Affinity Capture-MS
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Affinity Capture-MS
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B physical 1 1 1 Affinity Capture-MS
NFS1 YCL017C Cysteine desulfurase involved in iron-sulfur cluster biogenesis genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
NTH1 YDR001C Neutral trehalase, degrades trehalose physical 1 1 1 Affinity Capture-MS
HXK1 YFR053C Hexokinase isoenzyme 1 physical 1 1 1 Affinity Capture-MS
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-MS
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Positive Genetic
GUK1 YDR454C Guanylate kinase physical 1 1 1 Affinity Capture-MS
ISD11 YER048W-A Cysteine desulfurase (Nfs1p) activator genetic 1 1 1 Negative Genetic
DDR48 YMR173W DNA damage-responsive protein physical 1 1 1 Affinity Capture-MS
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase physical 1 1 1 Affinity Capture-MS
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
CRS1 YNL247W Cysteinyl-tRNA synthetase physical 1 1 1 Affinity Capture-MS
CUE3 YGL110C Subunit of ribosome-associated quality control trigger complex (RQT) genetic 1 1 1 Negative Genetic
PPT1 YGR123C Protein serine/threonine phosphatase physical 1 1 1 Affinity Capture-MS
PPX1 YHR201C Exopolyphosphatase physical 1 1 1 Affinity Capture-MS
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
OLE1 YGL055W Delta(9) fatty acid desaturase physical 1 1 1 Affinity Capture-MS
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway physical 1 1 1 Affinity Capture-Western
ADE12 YNL220W Adenylosuccinate synthase physical 1 1 1 Affinity Capture-MS
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ERV2 YPR037C Flavin-linked sulfhydryl oxidase localized to the ER lumen physical 1 1 1 Affinity Capture-MS
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
LAG2 YOL025W Protein that negatively regulates the SCF E3-ubiquitin ligase genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
ALD4 YOR374W Mitochondrial aldehyde dehydrogenase physical 1 1 1 Affinity Capture-MS
CYC7 YEL039C Cytochrome c isoform 2, expressed under hypoxic conditions physical 1 1 1 Affinity Capture-MS
OXP1 YKL215C 5-oxoprolinase physical 1 1 1 Affinity Capture-MS
FCY1 YPR062W Cytosine deaminase physical 1 1 1 Affinity Capture-MS
PHO13 YDL236W Conserved phosphatase acting as a metabolite repair enzyme physical 1 1 1 Affinity Capture-MS
ARO3 YDR035W 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase physical 1 1 1 Affinity Capture-MS
RPL4B YDR012W Ribosomal 60S subunit protein L4B physical 1 1 1 Affinity Capture-MS
ACL4 YDR161W Specific assembly chaperone for ribosomal protein Rpl4a/Rpl4b physical 1 1 1 Affinity Capture-MS
RPL17B YJL177W Ribosomal 60S subunit protein L17B physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B physical 1 1 1 Affinity Capture-MS
RPL6B YLR448W Ribosomal 60S subunit protein L6B genetic 1 1 1 Negative Genetic
RPL8A YHL033C Ribosomal 60S subunit protein L8A physical 1 1 1 Affinity Capture-MS
RPL33B YOR234C Ribosomal 60S subunit protein L33B physical 1 1 1 Affinity Capture-MS
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
RPL43A YPR043W Ribosomal 60S subunit protein L43A genetic 1 1 1 Negative Genetic
RPL6A YML073C Ribosomal 60S subunit protein L6A physical 1 1 1 Affinity Capture-MS
RPL6A YML073C Ribosomal 60S subunit protein L6A genetic 1 1 1 Negative Genetic
GVP36 YIL041W BAR domain protein that localizes to early and late Golgi vesicles physical 1 1 1 Affinity Capture-MS
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase physical 1 1 1 Affinity Capture-MS
RPL35B YDL136W Ribosomal 60S subunit protein L35B physical 1 1 1 Affinity Capture-MS
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Negative Genetic
RPL34A YER056C-A Ribosomal 60S subunit protein L34A genetic 1 1 1 Negative Genetic
ABP140 YOR239W AdoMet-dependent tRNA methyltransferase and actin binding protein physical 1 1 1 Affinity Capture-MS
CMK2 YOL016C Calmodulin-dependent protein kinase physical 1 1 1 Affinity Capture-MS
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein physical 1 1 1 Affinity Capture-MS
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase physical 1 1 1 Affinity Capture-MS
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
MNR2 YKL064W Vacuolar membrane protein required for magnesium homeostasis genetic 1 1 1 Negative Genetic
HIS5 YIL116W Histidinol-phosphate aminotransferase physical 1 1 1 Affinity Capture-MS
RNH70 YGR276C 3'-5' exoribonuclease physical 1 1 1 Affinity Capture-MS
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
MET2 YNL277W L-homoserine-O-acetyltransferase genetic 1 1 1 Negative Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
CYT1 YOR065W Cytochrome c1 physical 1 1 1 Affinity Capture-MS
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 1 1 1 Positive Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
KTR1 YOR099W Alpha-1,2-mannosyltransferase physical 1 1 1 Affinity Capture-MS
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase physical 1 1 1 Affinity Capture-MS
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase physical 1 1 1 Affinity Capture-MS
RIB1 YBL033C GTP cyclohydrolase II physical 1 1 1 Affinity Capture-MS
ASP1 YDR321W Cytosolic L-asparaginase, involved in asparagine catabolism physical 1 1 1 Affinity Capture-MS
MRX18 YBR056W Putative glycoside hydrolase of the mitochondrial intermembrane space physical 1 1 1 Affinity Capture-MS
HEM2 YGL040C Aminolevulinate dehydratase physical 1 1 1 Affinity Capture-MS
RIM13 YMR154C Calpain-like cysteine protease genetic 1 1 1 Negative Genetic
CHS2 YBR038W Chitin synthase II genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Synthetic Growth Defect
PCS60 YBR222C Oxalyl-CoA synthetase physical 1 1 1 Affinity Capture-MS
NPR1 YNL183C Protein kinase physical 1 1 1 Affinity Capture-MS
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 1 1 1 Negative Genetic
RER2 YBR002C Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 genetic 1 1 1 Positive Genetic
RBS1 YDL189W Protein involved in assembly of the RNA Pol III complex genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Positive Genetic
NIT3 YLR351C Nit protein physical 1 1 1 Affinity Capture-MS
RMR1 YGL250W Protein required for meiotic recombination and gene conversion genetic 1 1 1 Positive Genetic
NRE1 YIR035C Putative cytoplasmic short-chain dehydrogenase/reductase physical 1 1 1 Affinity Capture-MS
IRC24 YIR036C Putative benzil reductase physical 1 1 1 Affinity Capture-MS
CHO1 YER026C Phosphatidylserine synthase physical 1 1 1 Affinity Capture-MS
DAK1 YML070W Dihydroxyacetone kinase physical 1 1 1 Affinity Capture-MS
DAN4 YJR151C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase physical 1 1 1 Affinity Capture-MS
MET13 YGL125W Major isozyme of methylenetetrahydrofolate reductase physical 1 1 1 Affinity Capture-MS
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase physical 1 1 1 Affinity Capture-MS
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
HIS1 YER055C ATP phosphoribosyltransferase physical 1 1 1 Affinity Capture-MS
RPL33A YPL143W Ribosomal 60S subunit protein L33A physical 1 1 1 Affinity Capture-MS
MYG1 YER156C Protein involved in mitochondrial function physical 1 1 1 Affinity Capture-MS
CBP4 YGR174C Mitochondrial protein required for assembly of cytochrome bc1 complex genetic 1 1 1 Negative Genetic
COQ21 YBR230W-A Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
LSC2 YGR244C Beta subunit of succinyl-CoA ligase physical 1 1 1 Affinity Capture-MS
FSH3 YOR280C Putative serine hydrolase physical 1 1 1 Affinity Capture-MS
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
LOG1 YJL055W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
GLD1 YPR109W Component of Dsc E3 ligase complex in Golgi and endosomes genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex genetic 1 1 1 Positive Genetic
MSS2 YDL107W Peripherally bound inner membrane protein of the mitochondrial matrix genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Positive Genetic
ENB1 YOL158C Ferric enterobactin transmembrane transporter physical 1 1 1 Affinity Capture-MS
GCV2 YMR189W P subunit of the mitochondrial glycine decarboxylase complex physical 1 1 1 Affinity Capture-MS
NMA111 YNL123W Serine protease and general molecular chaperone physical 1 1 1 Affinity Capture-MS
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate physical 1 1 1 Affinity Capture-MS
RPL21B YPL079W Ribosomal 60S subunit protein L21B physical 1 1 1 Affinity Capture-MS
RPL21B YPL079W Ribosomal 60S subunit protein L21B genetic 1 1 1 Negative Genetic
PIC2 YER053C Mitochondrial copper and phosphate carrier genetic 1 1 1 Negative Genetic
NHX1 YDR456W Na+/H+ and K+/H+ exchanger genetic 1 1 1 Negative Genetic
RIB2 YOL066C Bifunctional DRAP deaminase tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
CTS2 YDR371W Putative chitinase genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Negative Genetic
MRX11 YPL041C Protein that associates with mitochondrial ribosome genetic 1 1 1 Negative Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Negative Genetic
LDB16 YCL005W Protein involved in lipid droplet (LD) assembly genetic 1 1 1 Negative Genetic
HXT13 YEL069C Putative transmembrane polyol transporter genetic 1 1 1 Negative Genetic
RCH1 YMR034C Negative regulator of cytosolic calcium homeostasis genetic 1 1 1 Negative Genetic