RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
14 |
4 |
10 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex |
WTM1 |
YOR230W |
Transcriptional modulator |
physical |
8 |
4 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-Western, Co-localization, Affinity Capture-Western, Affinity Capture-Western |
WTM2 |
YOR229W |
Transcriptional modulator |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-purification |
RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
3 |
3 |
3 |
Two-hybrid, Co-crystal Structure, Reconstituted Complex |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
3 |
3 |
3 |
Affinity Capture-MS, Co-crystal Structure, FRET |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
3 |
2 |
3 |
chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
HUG1 |
YML058W-A |
Ribonucleotide reductase inhibitor |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
HUG1 |
YML058W-A |
Ribonucleotide reductase inhibitor |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Phenotypic Suppression |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
physical |
2 |
1 |
1 |
Biochemical Activity, Biochemical Activity |
DIF1 |
YLR437C |
Protein that regulates nuclear import of Rnr2p and Rnr4p |
physical |
2 |
1 |
1 |
Reconstituted Complex, Reconstituted Complex |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
AFT1 |
YGL071W |
Transcription factor involved in iron utilization and homeostasis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC40 |
YDR364C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ASF1 |
YJL115W |
Nucleosome assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BNI1 |
YNL271C |
Formin |
physical |
1 |
1 |
1 |
Reconstituted Complex |
CYR1 |
YJL005W |
Adenylate cyclase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MEC1 |
YBR136W |
Genome integrity checkpoint protein and PI kinase superfamily member |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
NHP6B |
YBR089C-A |
High-mobility group (HMG) protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP8 |
YHR169W |
ATPase, putative RNA helicase of the DEAD-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
1 |
1 |
1 |
Dosage Lethality |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DRE2 |
YKR071C |
Component of the cytosolic Fe-S protein assembly (CIA) machinery |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RAD10 |
YML095C |
Single-stranded DNA endonuclease (with Rad1p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACO1 |
YLR304C |
Aconitase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GND1 |
YHR183W |
6-phosphogluconate dehydrogenase (decarboxylating) |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEN15 |
YMR059W |
Subunit of the tRNA splicing endonuclease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIR3 |
YLR442C |
Silencing protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TIS11 |
YLR136C |
mRNA-binding protein expressed during iron starvation |
physical |
1 |
1 |
1 |
Two-hybrid |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
UBP10 |
YNL186W |
Ubiquitin-specific protease, deubiquitinates Ub-protein moieties |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPO16 |
YHR153C |
Meiosis-specific protein involved in synaptonemal complex assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL11A |
YPR102C |
Ribosomal 60S subunit protein L11A |
genetic |
1 |
1 |
1 |
Negative Genetic |
SML1 |
YML058W |
Ribonucleotide reductase inhibitor |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP122 |
YGL016W |
Karyopherin beta |
physical |
1 |
1 |
1 |
Co-localization |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACO2 |
YJL200C |
Putative mitochondrial aconitase isozyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
1 |
1 |
1 |
Dosage Rescue |
DPH1 |
YIL103W |
Protein required for synthesis of diphthamide |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP15 |
YPL271W |
Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC7 |
YFR055W |
Cysteine desulphydrase, enables growth on cysteine as nitrogen source |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTH1 |
YDR151C |
mRNA binding protein, member of the CCCH zinc finger family |
physical |
1 |
1 |
1 |
Two-hybrid |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |