RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
physical |
11 |
5 |
7 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Co-crystal Structure, Protein-peptide, Two-hybrid, Affinity Capture-Western |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
genetic |
9 |
4 |
6 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Synthetic Growth Defect |
RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
physical |
8 |
3 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
8 |
3 |
5 |
Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Dosage Growth Defect, Positive Genetic, Positive Genetic |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
7 |
4 |
7 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Dosage Lethality, Negative Genetic, Synthetic Growth Defect |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
7 |
2 |
5 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
7 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
7 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
physical |
6 |
3 |
4 |
Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
6 |
3 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
6 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
6 |
2 |
4 |
Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
6 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
5 |
2 |
5 |
Positive Genetic, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Positive Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
BRE2 |
YLR015W |
Subunit of COMPASS (Set1C) complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
MMS4 |
YBR098W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
5 |
2 |
4 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
5 |
2 |
3 |
Positive Genetic, Positive Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
5 |
2 |
3 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
5 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RIF1 |
YBR275C |
Protein involved in control of DNA replication |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
LRS4 |
YDR439W |
Nucleolar protein that forms a complex with Csm1p |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Lethality, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality |
HST3 |
YOR025W |
Sirtuin, histone H3 deacetylase |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SDC1 |
YDR469W |
Subunit of the COMPASS (Set1C) complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
3 |
3 |
2 |
Negative Genetic, Synthetic Growth Defect, Dosage Rescue |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
3 |
2 |
2 |
Positive Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
RAD5 |
YLR032W |
DNA helicase/Ubiquitin ligase |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
MUS81 |
YDR386W |
Subunit of structure-specific Mms4p-Mus81p endonuclease |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
3 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
HTA1 |
YDR225W |
Histone H2A |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RAD54 |
YGL163C |
DNA-dependent ATPase that stimulates strand exchange |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PSH1 |
YOL054W |
E3 ubiquitin ligase targeting centromere-binding protein Cse4p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SAE2 |
YGL175C |
Endonuclease required for telomere elongation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRC5 |
YFR038W |
Putative ATPase containing the DEAD/H helicase-related sequence motif |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
KIP3 |
YGL216W |
Kinesin-related antiparallel sliding motor protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MCH5 |
YOR306C |
Plasma membrane riboflavin transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
EAF1 |
YDR359C |
Component of the NuA4 histone acetyltransferase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
RTT101 |
YJL047C |
Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Positive Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Suppression |
SIR2 |
YDL042C |
Conserved NAD+ dependent histone deacetylase of the Sirtuin family |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Phenotypic Suppression |
SLX4 |
YLR135W |
Endonuclease involved in processing DNA |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SUT1 |
YGL162W |
Zn(II)2Cys6 family transcription factor |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
HHF1 |
YBR009C |
Histone H4 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HTB2 |
YBL002W |
Histone H2B |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
HHT1 |
YBR010W |
Histone H3 |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RTT107 |
YHR154W |
BRCA1 C-terminal domain protein needed for recovery from DNA damage |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
STM1 |
YLR150W |
Protein required for optimal translation under nutrient stress |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPT2 |
YDL007W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAV1 |
YJR033C |
Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
URE2 |
YNL229C |
Nitrogen catabolite repression transcriptional regulator |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RNH202 |
YDR279W |
Ribonuclease H2 subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HST4 |
YDR191W |
NAD(+)-dependent protein deacetylase |
genetic |
2 |
1 |
2 |
Synthetic Rescue, Synthetic Rescue |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Synthetic Growth Defect |
CDC45 |
YLR103C |
DNA replication initiation factor |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
MCM6 |
YGL201C |
Protein involved in DNA replication |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
MCM2 |
YBL023C |
Protein involved in DNA replication |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
SLD5 |
YDR489W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
2 |
2 |
1 |
Affinity Capture-MS, Affinity Capture-Western |
MRE11 |
YMR224C |
Nuclease subunit of the MRX complex with Rad50p and Xrs2p |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Synthetic Growth Defect |
XRS2 |
YDR369C |
FHA domain-containing component of the Mre11 complex |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Synthetic Growth Defect |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
physical |
2 |
2 |
1 |
Two-hybrid, Reconstituted Complex |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
2 |
2 |
1 |
Synthetic Lethality, Dosage Rescue |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARD1 |
YHR013C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
EPL1 |
YFL024C |
Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
DUN1 |
YDL101C |
Cell-cycle checkpoint S/T protein kinase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HHT1 |
YBR010W |
Histone H3 |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PAC11 |
YDR488C |
Dynein intermediate chain, microtubule motor protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YLL058W |
YLL058W |
Putative protein of unknown function with similarity to Str2p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD55 |
YDR076W |
Protein that stimulates strand exchange |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD51 |
YER095W |
Strand exchange protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD57 |
YDR004W |
Protein that stimulates strand exchange |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
NAT1 |
YDL040C |
Subunit of protein N-terminal acetyltransferase NatA |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
POP2 |
YNR052C |
Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DPC29 |
YGR021W |
Putative mitochondrial protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CYB5 |
YNL111C |
Cytochrome b5 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
INO2 |
YDR123C |
Transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
DED81 |
YHR019C |
Cytosolic asparaginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LEO1 |
YOR123C |
Component of the Paf1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESF1 |
YDR365C |
Nucleolar protein involved in pre-rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENP2 |
YGR145W |
Component of the SSU |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRX1 |
YOL077C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP9 |
YLR276C |
DEAD-box protein required for 27S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EBP2 |
YKL172W |
Required for 25S rRNA maturation and 60S ribosomal subunit assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK16 |
YAL025C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD6 |
YDR211W |
Catalytic epsilon subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COR1 |
YBL045C |
Core subunit of the ubiquinol-cytochrome c reductase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE29 |
YER038C |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIC1 |
YHR052W |
Essential protein that interacts with proteasome components |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC1 |
YGL105W |
Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH1 |
YER177W |
14-3-3 protein, major isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSL4 |
YNL232W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MED7 |
YOL135C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BCP1 |
YDR361C |
Essential nuclear chaperone for ribosomal protein Rpl23p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE13 |
YLR359W |
Adenylosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BAT1 |
YHR208W |
Mitochondrial branched-chain amino acid (BCAA) aminotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BDF1 |
YLR399C |
BET family transcriptional regulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BMH2 |
YDR099W |
14-3-3 protein, minor isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAR1 |
YPL111W |
Arginase, catabolizes arginine to ornithine and urea |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHC1 |
YGL206C |
Clathrin heavy chain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPR1 |
YDR155C |
Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
DPB2 |
YPR175W |
Second largest subunit of DNA polymerase II (DNA polymerase epsilon) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENO1 |
YGR254W |
Enolase I, a phosphopyruvate hydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FPR1 |
YNL135C |
Peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN1 |
YGL195W |
Positive regulator of the Gcn2p kinase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLY1 |
YEL046C |
Threonine aldolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIS4 |
YCL030C |
Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRT1 |
YOL133W |
RING-H2 domain core subunit of multiple ubiquitin ligase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DPB4 |
YDR121W |
Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
IST1 |
YNL265C |
Protein with positive role in the multivesicular body sorting pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESC8 |
YOL017W |
Protein involved in telomeric and mating-type locus silencing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISW2 |
YOR304W |
ATP-dependent DNA translocase involved in chromatin remodeling |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARB1 |
YER036C |
ATPase of the ATP-binding cassette (ABC) family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRE33 |
YNL132W |
Acetyltransferase required for biogenesis of small ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRS1 |
YDR037W |
Lysyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GFA1 |
YKL104C |
Glutamine-fructose-6-phosphate amidotransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GLT1 |
YDL171C |
NAD(+)-dependent glutamate synthase (GOGAT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GAL11 |
YOL051W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HRR25 |
YPL204W |
Conserved casein kinase, monopolin subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMG1 |
YCR046C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MHR1 |
YDR296W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCM1 |
YGR150C |
Mitochondrial 15S rRNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR1 |
YDL156W |
Nuclear protein with role in transcription, protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAP114 |
YGL241W |
Karyopherin, responsible for nuclear import of specific proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
LYS12 |
YIL094C |
Homo-isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
INO80 |
YGL150C |
Nucleosome spacing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP42 |
YDR171W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HMO1 |
YDR174W |
Chromatin associated high mobility group (HMG) family member |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LAT1 |
YNL071W |
Dihydrolipoamide acetyltransferase component (E2) of the PDC |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIG1 |
YPL049C |
MAP kinase-responsive inhibitor of the Ste12p transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IDH2 |
YOR136W |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMP4 |
YNL075W |
Component of the SSU processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPA2 |
YJR109C |
Large subunit of carbamoyl phosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MKT1 |
YNL085W |
Protein similar to nucleases that forms a complex with Pbp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE57 |
YGL234W |
Bifunctional enzyme of 'de novo' purine nucleotide pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ADE3 |
YGR204W |
Cytoplasmic trifunctional enzyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAF1 |
YDR005C |
Highly conserved negative regulator of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC6 |
YJL194W |
Essential ATP-binding protein required for DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BGL2 |
YGR282C |
Endo-beta-1,3-glucanase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT2 |
YIL142W |
Subunit beta of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC25 |
YLR310C |
Membrane bound guanine nucleotide exchange factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSB3 |
YFR024C-A |
Protein containing a C-terminal SH3 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST2 |
YBR086C |
Cortical ER protein involved in ER-plasma membrane (PM) tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAM1 |
YPL048W |
One of two isoforms of the gamma subunit of eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFB1 |
YAL003W |
Translation elongation factor 1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LTV1 |
YKL143W |
Subunit of the EGO/GSE complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOT6 |
YER088C |
Protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSM12 |
YHR121W |
Protein of unknown function that may function in RNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LYS9 |
YNR050C |
Saccharopine dehydrogenase (NADP+, L-glutamate-forming) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FPR3 |
YML074C |
Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGD2 |
YHR193C |
Alpha subunit of the nascent polypeptide-associated complex (NAC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACO1 |
YLR304C |
Aconitase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDH1 |
YKL085W |
Mitochondrial malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDH1 |
YNL037C |
Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CPR6 |
YLR216C |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AHP1 |
YLR109W |
Thiol-specific peroxiredoxin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMP2 |
YML057W |
Calcineurin A |
genetic |
1 |
1 |
1 |
Positive Genetic |
DPS1 |
YLL018C |
Aspartyl-tRNA synthetase, primarily cytoplasmic |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GSP1 |
YLR293C |
Ran GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FAA4 |
YMR246W |
Long chain fatty acyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARO4 |
YBR249C |
3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV5 |
YLR355C |
Acetohydroxyacid reductoisomerase and mtDNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKH1 |
YIL131C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HXT6 |
YDR343C |
High-affinity glucose transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAT2 |
YLR027C |
Cytosolic aspartate aminotransferase involved in nitrogen metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADK1 |
YDR226W |
Adenylate kinase, required for purine metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPD2 |
YOL059W |
NAD-dependent glycerol 3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPD1 |
YDL022W |
NAD-dependent glycerol-3-phosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM10 |
YEL030W |
Heat shock protein of the Hsp70 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARG4 |
YHR018C |
Argininosuccinate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LIA1 |
YJR070C |
Deoxyhypusine hydroxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DLD3 |
YEL071W |
2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV3 |
YJR016C |
Dihydroxyacid dehydratase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADH3 |
YMR083W |
Mitochondrial alcohol dehydrogenase isozyme III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IMD4 |
YML056C |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSK2 |
YMR276W |
Nuclear-enriched ubiquitin-like polyubiquitin-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC60 |
YPL160W |
Cytosolic leucyl tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GRS1 |
YBR121C |
Cytoplasmic and mitochondrial glycyl-tRNA synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG20 |
YJL167W |
Farnesyl pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET6 |
YER091C |
Cobalamin-independent methionine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
LRO1 |
YNR008W |
Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRS2 |
YFL022C |
Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCX1 |
YBR227C |
Non-proteolytic ATPase of the AAA family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAC2 |
YML102W |
Subunit of chromatin assembly factor I (CAF-1), with Rlf2p and Msi1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACS1 |
YAL054C |
Acetyl-coA synthetase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV2 |
YMR108W |
Acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAP2 |
YBL091C |
Methionine aminopeptidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDH2 |
YOL126C |
Cytoplasmic malate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APA1 |
YCL050C |
AP4A phosphorylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM4 |
YPR019W |
Essential helicase component of heterohexameric MCM2-7 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAP1 |
YKL204W |
eIF4E-associated protein, competes with eIF4G for binding to eIF4E |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIA1 |
YDR267C |
Component of cytosolic iron-sulfur protein assembly (CIA) machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GBP2 |
YCL011C |
Poly(A+) RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDJ1 |
YFL016C |
Co-chaperone that stimulates HSP70 protein Ssc1p ATPase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARG1 |
YOL058W |
Arginosuccinate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CYS3 |
YAL012W |
Cystathionine gamma-lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APE3 |
YBR286W |
Vacuolar aminopeptidase Y |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP45 |
YAL032C |
Protein required for pre-mRNA splicing |
physical |
1 |
1 |
1 |
Two-hybrid |
SSA3 |
YBL075C |
ATPase involved in protein folding and the response to stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP1 |
YDL014W |
Histone glutamine methyltransferase, modifies H2A at Q105 in nucleolus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TDH1 |
YJL052W |
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR187C |
YMR187C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YIL082W-A |
YIL082W-A |
Retrotransposon TYA Gag and TYB Pol genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL43A |
YPR043W |
Ribosomal 60S subunit protein L43A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSR1 |
YGR159C |
Nucleolin, nucleolar protein that binds nuclear localization sequences |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP1B |
YDL130W |
Ribosomal protein P1 beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS29B |
YDL061C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31B |
YLR406C |
Ribosomal 60S subunit protein L31B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS23A |
YGR118W |
Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS10B |
YMR230W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS30A |
YLR287C-A |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL19 |
YNL185C |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET130 |
YJL023C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET130 |
YJL023C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TUB3 |
YML124C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP12 |
YOL041C |
Nucleolar protein involved in pre-25S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAL1 |
YLR354C |
Transaldolase, enzyme in the non-oxidative pentose phosphate pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL18A |
YOL120C |
Ribosomal 60S subunit protein L18A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL38 |
YLR325C |
Ribosomal 60S subunit protein L38 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL37A |
YLR185W |
Ribosomal 60S subunit protein L37A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL15A |
YLR029C |
Ribosomal 60S subunit protein L15A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS26A |
YGL189C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS29A |
YLR388W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAR1 |
YPL218W |
ARF family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL1A |
YPL220W |
Ribosomal 60S subunit protein L1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP6 |
YDL213C |
rRNA-binding protein required for 40S ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRG8 |
YPR116W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TSA1 |
YML028W |
Thioredoxin peroxidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRT4 |
YKL009W |
Protein involved in mRNA turnover and ribosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP13 |
YNL175C |
Nucleolar protein found in preribosomal complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL33A |
YPL143W |
Ribosomal 60S subunit protein L33A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THG1 |
YGR024C |
tRNAHis guanylyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL33B |
YOR234C |
Ribosomal 60S subunit protein L33B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL19A |
YBR084C-A |
Ribosomal 60S subunit protein L19A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YEF3 |
YLR249W |
Translation elongation factor 3 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCR016W |
YCR016W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP58 |
YOR310C |
Protein involved in producing mature rRNAs and snoRNAs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT1 |
YFL038C |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL24B |
YGR148C |
Ribosomal 60S subunit protein L24B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC40 |
YPR110C |
RNA polymerase subunit AC40 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC4 |
YFL005W |
Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHB1 |
YGR234W |
Nitric oxide oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PNO1 |
YOR145C |
Essential nucleolar protein required for pre-18S rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SER3 |
YER081W |
3-phosphoglycerate dehydrogenase and alpha-ketoglutarate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUB1 |
YML085C |
Alpha-tubulin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSA1 |
YDL055C |
GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSZ1 |
YHR064C |
Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRP3 |
YHR065C |
Protein involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPF2 |
YKR081C |
Essential protein involved in rRNA maturation and ribosomal assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP4 |
YPL043W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSM23 |
YGL129C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP10 |
YHR072W-A |
Subunit of box H/ACA snoRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC3 |
YNL290W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS35 |
YGR165W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RIO2 |
YNL207W |
Essential serine kinase involved in the processing of 20S pre-rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUS6 |
YGR169C |
tRNA:pseudouridine synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL34B |
YIL052C |
Ribosomal 60S subunit protein L34B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RNR2 |
YJL026W |
Ribonucleotide-diphosphate reductase (RNR), small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PPH21 |
YDL134C |
Catalytic subunit of protein phosphatase 2A, PP2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
URA3 |
YEL021W |
Orotidine-5'-phosphate (OMP) decarboxylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG1 |
YPL093W |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP23 |
YOR004W |
Component of the small subunit processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT32 |
YGL210W |
Rab family GTPase involved in the exocytic pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRB1 |
YEL060C |
Vacuolar proteinase B (yscB) with H3 N-terminal endopeptidase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHM2 |
YLR058C |
Cytosolic serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR226C |
YMR226C |
NADP(+)-dependent serine dehydrogenase and carbonyl reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT3 |
YDR394W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM9 |
YNL137C |
Mitochondrial ribosomal component of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP24 |
YLR009W |
Essential protein required for ribosomal large subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOD6 |
YBL054W |
PAC motif binding protein involved in rRNA and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP51 |
YPL118W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAB1 |
YER165W |
Poly(A) binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOG2 |
YNR053C |
Putative GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP15 |
YNL110C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP15 |
YPR143W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPA135 |
YPR010C |
RNA polymerase I second largest subunit A135 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA4 |
YOR332W |
Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS5 |
YOL061W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC53 |
YFL045C |
Phosphomannomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB8 |
YOR224C |
RNA polymerase subunit ABC14.5 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP4 |
YHL004W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP1 |
YDR347W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN3 |
YER021W |
Essential non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPF1 |
YHR088W |
Protein involved in assembly and export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SES1 |
YDR023W |
Cytosolic seryl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSF3 |
YOL146W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PST2 |
YDR032C |
FMN-dependent NAD(P)H:quinone oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL42A |
YNL162W |
Ribosomal 60S subunit protein L42A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNR4 |
YGR180C |
Ribonucleotide-diphosphate reductase (RNR) small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP14 |
YDL092W |
Signal recognition particle (SRP) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NET1 |
YJL076W |
Core subunit of the RENT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THR1 |
YHR025W |
Homoserine kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SKP1 |
YDR328C |
Evolutionarily conserved kinetochore protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS12 |
YNR036C |
Mitochondrial protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TYS1 |
YGR185C |
Cytoplasmic tyrosyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WTM1 |
YOR230W |
Transcriptional modulator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC14 |
YMR079W |
Phosphatidylinositol/phosphatidylcholine transfer protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCJ1 |
YMR214W |
One of several homologs of bacterial chaperone DnaJ |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNP1 |
YIL061C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS8 |
YMR158W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOD2 |
YHR008C |
Mitochondrial manganese superoxide dismutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PDX1 |
YGR193C |
E3-binding protein of the mitochondrial pyruvate dehydrogenase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REH1 |
YLR387C |
Cytoplasmic 60S subunit biogenesis factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRP17 |
YKL003C |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCK1 |
YKR097W |
Phosphoenolpyruvate carboxykinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YCR087C-A |
YCR087C-A |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR315W |
YMR315W |
Protein with NADP(H) oxidoreductase activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POL4 |
YCR014C |
DNA polymerase IV |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNP1 |
YGL068W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU13 |
YEL026W |
RNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMY2 |
YBR172C |
GYF domain protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP4 |
YDL053C |
Pbp1p binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP5 |
YGL026C |
Tryptophan synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNU114 |
YKL173W |
GTPase component of U5 snRNP involved in mRNA splicing via spliceosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPI1 |
YFR003C |
Regulatory subunit of the type I protein phosphatase (PP1) Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL15 |
YLR312W-A |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NHP2 |
YDL208W |
Protein related to mammalian high mobility group (HMG) proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL35 |
YDR322W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPL11 |
YDL202W |
Mitochondrial ribosomal protein of the large subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCL1 |
YOL010W |
Endonuclease that cleaves pre-rRNA at site A2 for 18S rRNA biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF7 |
YLR025W |
One of four subunits of the ESCRT-III complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDH2 |
YLL041C |
Iron-sulfur protein subunit of succinate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNQ1 |
YCL028W |
[PIN(+)] prion |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUP2 |
YGR253C |
Alpha 5 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPR148C |
YPR148C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKL075C |
YKL075C |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRS1 |
YKL181W |
5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHE1 |
YBL031W |
Mitotic spindle protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSA2 |
YER126C |
Protein constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN9 |
YDR427W |
Non-ATPase regulatory subunit of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TKL1 |
YPR074C |
Transketolase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS9 |
YBR146W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS5 |
YBR251W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPM1 |
YJL066C |
Mitochondrial intermembrane space protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP1 |
YLR196W |
Protein with WD-40 repeats involved in rRNA processing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YPT52 |
YKR014C |
Endosomal Rab family GTPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PCS60 |
YBR222C |
Oxalyl-CoA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VLD1 |
YIR014W |
Component of Dsc E3 ligase complex in vacuolar membranes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTN1 |
YDR233C |
Reticulon protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRM1 |
YDR120C |
tRNA methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDR341C |
YDR341C |
Arginyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YKL107W |
YKL107W |
NADH-dependent aldehyde reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSA4 |
YCR072C |
Ribosomal large subunit (60S) assembly factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PET123 |
YOR158W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP22 |
YGR090W |
Component of the small-subunit processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP40 |
YKR092C |
Nucleolar serine-rich protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF5 |
YBR289W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRB5 |
YGR104C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RNR1 |
YER070W |
Major isoform of large subunit of ribonucleotide-diphosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGR130C |
YGR130C |
Component of the eisosome with unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAR1 |
Q0140 |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SVF1 |
YDR346C |
Protein with a potential role in cell survival pathways |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROK1 |
YGL171W |
RNA-dependent ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAS1 |
YGR094W |
Mitochondrial and cytoplasmic valyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP7 |
YCL031C |
Essential protein involved in rRNA processing and ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTR2 |
YEL040W |
Chitin transglycosylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNZ1 |
YMR096W |
Subunit of a two-component pyridoxal-5'-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGR017W |
YGR017W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SHM1 |
YBR263W |
Mitochondrial serine hydroxymethyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBE22 |
YHR103W |
Protein involved in bud growth |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UFD4 |
YKL010C |
Ubiquitin-protein ligase (E3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP15 |
YMR093W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PGM2 |
YMR105C |
Phosphoglucomutase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MRPS28 |
YDR337W |
Mitochondrial ribosomal protein of the small subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PWP2 |
YCR057C |
Conserved 90S pre-ribosomal component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROD1 |
YOR018W |
Alpha-arrestin involved in ubiquitin-dependent endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB6 |
YML117W |
Putative RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YMR310C |
YMR310C |
Putative methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP7 |
YER082C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPR1 |
YNL183C |
Protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPR1 |
YNL183C |
Protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOP2 |
YNL088W |
Topoisomerase II |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOP2 |
YNL088W |
Topoisomerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE12 |
YHR084W |
Transcription factor that is activated by a MAPK signaling cascade |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRI1 |
YIR008C |
Subunit of DNA primase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOD5 |
YOR274W |
Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP68 |
YPL243W |
Core component of the signal recognition particle (SRP) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP14 |
YML093W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP7 |
YGR103W |
Component of several different pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP6 |
YDR449C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPP10 |
YJR002W |
Component of the SSU processome and 90S preribosome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NPR2 |
YEL062W |
Subunit of the Iml1p/SEACIT complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NAN1 |
YPL126W |
U3 snoRNP protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
STE11 |
YLR362W |
Signal transducing MEK kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RSC9 |
YML127W |
Component of the RSC chromatin remodeling complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRM3 |
YHR031C |
DNA helicase involved in rDNA replication and Ty1 transposition |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSC3 |
YLR219W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRP8 |
YHR165C |
Component of U4/U6-U5 snRNP complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP1 |
YOR098C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PYC1 |
YGL062W |
Pyruvate carboxylase isoform |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VID30 |
YGL227W |
Central component of GID Complex, involved in FBPase degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP9 |
YHR196W |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP9 |
YHR196W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RKM4 |
YDR257C |
Ribosomal lysine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF4632 |
YGL049C |
Translation initiation factor eIF4G and scaffold protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBA1 |
YKL210W |
Ubiquitin activating enzyme (E1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MSM1 |
YGR171C |
Mitochondrial methionyl-tRNA synthetase (MetRS) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SGD1 |
YLR336C |
Essential nuclear protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCH9 |
YHR205W |
AGC family protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YHR219W |
YHR219W |
Putative protein of unknown function with similarity to helicases |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VPH1 |
YOR270C |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TPS3 |
YMR261C |
Regulatory subunit of trehalose-6-phosphate synthase/phosphatase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RRP12 |
YPL012W |
Protein required for export of the ribosomal subunits |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLH1 |
YGR271W |
Subunit of ribosome-associated quality control trigger complex (RQT) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UTP20 |
YBL004W |
Component of the small-subunit (SSU) processome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSF2 |
YJL072C |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTS1 |
YOR359W |
Flap-structured DNA-binding and RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOP3 |
YLR234W |
DNA Topoisomerase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSY2 |
YNL201C |
Subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOD1 |
YJR104C |
Cytosolic copper-zinc superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA5 |
YML106W |
Major orotate phosphoribosyltransferase (OPRTase) isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM21 |
YNL294C |
pH sensor molecule, component of the RIM101 pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC2 |
YER007W |
Microtubule effector required for tubulin heterodimer formation |
genetic |
1 |
1 |
1 |
Positive Genetic |
YML119W |
YML119W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RAD14 |
YMR201C |
Subunit of Nucleotide Excision Repair Factor 1 (NEF1) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOT2 |
YER068W |
Ubiquitin-protein ligase subunit of the CCR4-NOT complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC6 |
YHR118C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RIM101 |
YHL027W |
Cys2His2 zinc-finger transcriptional repressor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIF1 |
YML061C |
DNA helicase, potent G-quadruplex DNA binder/unwinder |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD59 |
YDL059C |
Protein involved DNA double-strand break repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PEP5 |
YMR231W |
Histone E3 ligase, component of CORVET membrane tethering complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VPS36 |
YLR417W |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PEP3 |
YLR148W |
Component of CORVET membrane tethering complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SNF8 |
YPL002C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
STP22 |
YCL008C |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VPS25 |
YJR102C |
Component of the ESCRT-II complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PPZ2 |
YDR436W |
Serine/threonine protein phosphatase Z, isoform of Ppz1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
WTM2 |
YOR229W |
Transcriptional modulator |
genetic |
1 |
1 |
1 |
Positive Genetic |
PKH1 |
YDR490C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
genetic |
1 |
1 |
1 |
Positive Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNT2 |
YGL131C |
Subunit of Snt2C complex, RING finger ubiquitin ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGK3 |
YOL128C |
Protein kinase related to mammalian GSK-3 glycogen synthase kinases |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRR1 |
YKL116C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG3 |
YBL103C |
bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB1 |
YNL309W |
Protein with role in regulation of MBF-specific transcription at Start |
genetic |
1 |
1 |
1 |
Negative Genetic |
PML1 |
YLR016C |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK3 |
YER123W |
Palmitoylated vacuolar membrane-localized casein kinase I isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
TYW3 |
YGL050W |
tRNA methyltransferase required for synthesis of wybutosine |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA22 |
YHR060W |
Protein that is required for vacuolar H+-ATPase (V-ATPase) function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MTG2 |
YHR168W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRPL10 |
YNL284C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC1 |
YDR177W |
Ubiquitin-conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA3 |
YJL173C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP21 |
YJL203W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDS5 |
YMR076C |
Cohesion maintenance factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC1 |
YOR217W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
UMP1 |
YBR173C |
Chaperone required for correct maturation of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR221W-A |
YBR221W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL177C |
YDL177C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR169C-A |
YDR169C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIZ1 |
YDR409W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR541C |
YDR541C |
Aldehyde reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTR4 |
YEL038W |
Protein with sequence similarity to acireductone synthases |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC2 |
YER089C |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX14 |
YGL153W |
Central component of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUP1 |
YGR055W |
High affinity methionine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR121W-A |
YGR121W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA5 |
YHL029C |
Cytoplasmic protein required for replication of Brome mosaic virus |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSC83 |
YHR017W |
Non-essential mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR022C-A |
YHR022C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
VID28 |
YIL017C |
GID Complex subunit, serves as adaptor for regulatory subunit Vid24p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN6 |
YIL145C |
Pantothenate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL070C |
YJL070C |
Putative metallo-dependent hydrolase superfamily protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMH11 |
YJR085C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR124C |
YJR124C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
XPT1 |
YJR133W |
Xanthine-guanine phosphoribosyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPK3 |
YKL166C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR005C |
YKR005C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP11 |
YKR098C |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPR1 |
YLR014C |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML037C |
YML037C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YML131W |
YML131W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR158C-A |
YMR158C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGL2 |
YMR285C |
Protein involved in 5.8S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKU80 |
YMR106C |
Subunit of telomeric Ku complex (Yku70p-Yku80p) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PLB3 |
YOL011W |
Phospholipase B (lysophospholipase) involved in lipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SFM1 |
YOR021C |
SPOUT methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB6 |
YOR352W |
Subunit of TFIIH complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR385W |
YOR385W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM3 |
YPL192C |
Protein required for nuclear envelope fusion during karyogamy |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPL229W |
YPL229W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROX1 |
YPR065W |
Heme-dependent repressor of hypoxic genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE7 |
YBL041W |
Beta 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SHR5 |
YOL110W |
Palmitoyltransferase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
1 |
1 |
1 |
Negative Genetic |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTT106 |
YNL206C |
Histone chaperone |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SMC5 |
YOL034W |
Subunit of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GDH2 |
YDL215C |
NAD(+)-dependent glutamate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ARG3 |
YJL088W |
Ornithine carbamoyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEU4 |
YNL104C |
Alpha-isopropylmalate synthase (2-isopropylmalate synthase) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IKS1 |
YJL057C |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM3 |
YMR048W |
Replication fork associated factor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
IME1 |
YJR094C |
Master regulator of meiosis that is active only during meiotic events |
genetic |
1 |
1 |
1 |
Negative Genetic |
JSN1 |
YJR091C |
Member of the Puf family of RNA-binding proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FOB1 |
YDR110W |
Nucleolar protein that binds the rDNA replication fork barrier site |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC9 |
YLR102C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DOC1 |
YGL240W |
Processivity factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEU3 |
YLR451W |
Zinc-knuckle transcription factor, repressor and activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
HPC2 |
YBR215W |
Subunit of the HIR complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
BNI5 |
YNL166C |
Linker protein responsible for recruitment of myosin to the bud neck |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM3 |
YEL032W |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRB1 |
YNL004W |
Poly(A+) RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MBF1 |
YOR298C-A |
Transcriptional coactivator |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESC1 |
YMR219W |
Protein involved in telomeric silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ESC2 |
YDR363W |
Sumo-like domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP1 |
YPL119C |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALY1 |
YKR021W |
Alpha arrestin, substrate of calcineurin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GIC2 |
YDR309C |
Rho-family GTPase interacting protein and Cdc42p effector |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMR2 |
YOR093C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIR1 |
YER032W |
Protein involved in 3' mRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYL1 |
YMR192W |
Putative GTPase activating protein (GAP) with a role in exocytosis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IVY1 |
YDR229W |
Phospholipid-binding protein that interacts with both Ypt7p and Vps33p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ACF2 |
YLR144C |
Intracellular beta-1,3-endoglucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CQD1 |
YPL109C |
UbiB family mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ETT1 |
YOR051C |
Nuclear protein that inhibits replication of Brome mosaic virus |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EIS1 |
YMR031C |
Component of the eisosome required for proper eisosome assembly |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP6 |
YNR038W |
Essential protein involved in ribosome biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
LEU1 |
YGL009C |
Isopropylmalate isomerase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MET1 |
YKR069W |
S-adenosyl-L-methionine uroporphyrinogen III transmethylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ASN2 |
YGR124W |
Asparagine synthetase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EUC1 |
YMR111C |
Sequence-specific DNA binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ILV6 |
YCL009C |
Regulatory subunit of acetolactate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EPO1 |
YMR124W |
Protein involved in septin-ER tethering |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLR1 |
YPL091W |
Cytosolic and mitochondrial glutathione oxidoreductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP26 |
YBR072W |
Small heat shock protein (sHSP) with chaperone activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CIT1 |
YNR001C |
Mitochondrial citrate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARR3 |
YPR201W |
Plasma membrane metalloid/H+ antiporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD22 |
YMR014W |
Protein required for rRNA maturation and ribosomal subunit biogenesis |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EGT2 |
YNL327W |
Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM14 |
YER014W |
Protoporphyrinogen oxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KTR2 |
YKR061W |
Mannosyltransferase involved in N-linked protein glycosylation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GTB1 |
YDR221W |
Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ATP16 |
YDL004W |
Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BOL3 |
YAL046C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MET17 |
YLR303W |
O-acetyl homoserine-O-acetyl serine sulfhydrylase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP12 |
YFL014W |
Plasma membrane protein involved in maintaining membrane organization |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GLK1 |
YCL040W |
Glucokinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AYT1 |
YLL063C |
Acetyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BUL2 |
YML111W |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICL1 |
YER065C |
Isocitrate lyase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GID11 |
YLR149C |
Substrate receptor of the glucose-induced degradation-deficient (GID) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACP1 |
YKL192C |
Mitochondrial matrix acyl carrier protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARG56 |
YER069W |
Acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CRS1 |
YNL247W |
Cysteinyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DTR1 |
YBR180W |
Putative dityrosine transporter of the major facilitator superfamily |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DIN7 |
YDR263C |
Mitochondrial nuclease functioning in DNA repair and replication |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDP1 |
YDL066W |
Mitochondrial NADP-specific isocitrate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALD4 |
YOR374W |
Mitochondrial aldehyde dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IRC19 |
YLL033W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IRC19 |
YLL033W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GEP5 |
YLR091W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GEP5 |
YLR091W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GVP36 |
YIL041W |
BAR domain protein that localizes to early and late Golgi vesicles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUA1 |
YMR217W |
GMP synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
APJ1 |
YNL077W |
Hsp40 chaperone with a role in SUMO-mediated protein degradation |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MAM1 |
YER106W |
Monopolin |
physical |
1 |
1 |
1 |
Two-hybrid |
LDB18 |
YLL049W |
Component of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MDM32 |
YOR147W |
Mitochondrial inner membrane protein with similarity to Mdm31p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO1 |
YJL153C |
Inositol-3-phosphate synthase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISC1 |
YER019W |
Inositol phosphosphingolipid phospholipase C |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD16 |
YEL029C |
Putative pyridoxal kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
FCY22 |
YER060W-A |
Putative purine-cytosine permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFT2 |
YPL202C |
Iron-regulated transcriptional activator |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GLO1 |
YML004C |
Monomeric glyoxalase I |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
EFM5 |
YGR001C |
S-adenosylmethionine-dependent lysine methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HIS1 |
YER055C |
ATP phosphoribosyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GTF1 |
YGR102C |
Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MIN8 |
YPR010C-A |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL31 |
YBR298C |
Maltose permease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DSC2 |
YOL073C |
Multi-transmembrane subunit of the DSC ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL33 |
YBR297W |
MAL-activator protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGO2 |
YCR075W-A |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM10 |
YER087W |
Protein with similarity to tRNA synthetases |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
AI2 |
Q0055 |
Reverse transcriptase required for splicing of the COX1 pre-mRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MET22 |
YOL064C |
Bisphosphate-3'-nucleotidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD25 |
YER014C-A |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
KCH1 |
YJR054W |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |