Standard name Systematic name Name description Description
RAD55 YDR076W Protein that stimulates strand exchange Protein that stimulates strand exchange; stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p
Visualize the interactome of RAD55
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.105 0.091 0.087
Mito 0.184 0.188 0.130
Nucleus 0.816 0.738 0.723
Vac/Vac Memb 0.184 0.097 0.147

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 1050

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
RAD55 4 1 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 20 7 16 Synthetic Rescue, Synthetic Rescue, Synthetic Growth Defect, Phenotypic Suppression, Dosage Lethality, Positive Genetic, Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Positive Genetic, Negative Genetic, Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Suppression
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 12 2 10 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange physical 11 3 9 Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Affinity Capture-Western
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 10 3 8 Synthetic Growth Defect, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 9 4 9 Dosage Rescue, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Positive Genetic, Phenotypic Suppression, Dosage Rescue, Synthetic Rescue, Positive Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 9 4 7 Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Phenotypic Suppression, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD51 YER095W Strand exchange protein physical 8 2 8 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 8 3 7 Synthetic Rescue, Synthetic Rescue, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Phenotypic Enhancement, Positive Genetic, Positive Genetic
NUP60 YAR002W FG-nucleoporin component of central core of the nuclear pore complex genetic 8 2 7 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 8 2 6 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 7 4 5 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Positive Genetic, Dosage Lethality
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 6 2 6 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Synthetic Rescue, Positive Genetic
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) physical 6 2 3 Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 5 3 4 Synthetic Growth Defect, Phenotypic Suppression, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement
REV1 YOR346W Deoxycytidyl transferase genetic 5 3 4 Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 5 2 4 Synthetic Rescue, Synthetic Rescue, Positive Genetic, Positive Genetic, Positive Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 5 3 3 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Positive Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 5 2 3 Negative Genetic, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 4 2 4 Positive Genetic, Positive Genetic, Phenotypic Suppression, Positive Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 3 3 Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 4 3 3 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Positive Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 4 3 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Positive Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 3 3 3 Synthetic Lethality, Negative Genetic, Synthetic Growth Defect
LTE1 YAL024C Protein similar to GDP/GTP exchange factors genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 3 2 3 Synthetic Rescue, Synthetic Rescue, Positive Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 3 3 2 Negative Genetic, Synthetic Lethality, Synthetic Growth Defect
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RPN10 YHR200W Proteasome polyubiquitin receptor genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect
RNH202 YDR279W Ribonuclease H2 subunit genetic 3 2 2 Synthetic Rescue, Synthetic Rescue, Negative Genetic
RAD53 YPL153C DNA damage response kinase physical 3 2 2 Biochemical Activity, Two-hybrid, Biochemical Activity
BIM1 YER016W Microtubule plus end-tracking protein genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Growth Defect
CSM3 YMR048W Replication fork associated factor genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Positive Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
REV7 YIL139C Accessory subunit of DNA polymerase zeta genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RFC4 YOL094C Subunit of heteropentameric Replication factor C (RF-C) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CTF4 YPR135W Chromatin-associated protein genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 3 1 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 2 2 2 Positive Genetic, Phenotypic Suppression
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Synthetic Lethality, Positive Genetic
MPH1 YIR002C 3'-5' DNA helicase involved in error-free bypass of DNA lesions genetic 2 2 2 Synthetic Rescue, Positive Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ORC2 YBR060C Subunit of the origin recognition complex (ORC) genetic 2 2 2 Synthetic Lethality, Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
ULP1 YPL020C Protease that specifically cleaves Smt3p protein conjugates genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 2 2 2 Synthetic Growth Defect, Synthetic Rescue
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 2 2 2 Synthetic Rescue, Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 2 2 Synthetic Growth Defect, Positive Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 2 2 2 Negative Genetic, Positive Genetic
DST1 YGL043W General transcription elongation factor TFIIS genetic 2 1 2 Negative Genetic, Negative Genetic
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I genetic 2 1 2 Negative Genetic, Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 2 1 2 Negative Genetic, Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member physical 2 1 2 Biochemical Activity, Biochemical Activity
SRS2 YJL092W DNA helicase and DNA-dependent ATPase physical 2 1 2 Reconstituted Complex, Reconstituted Complex
WHI5 YOR083W Repressor of G1 transcription genetic 2 1 2 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 2 1 2 Negative Genetic, Negative Genetic
HOM6 YJR139C Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) genetic 2 1 2 Negative Genetic, Negative Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 2 1 2 Negative Genetic, Negative Genetic
JLP1 YLL057C Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination physical 2 2 1 Two-hybrid, Reconstituted Complex
DIA2 YOR080W Origin-binding F-box protein genetic 2 2 1 Synthetic Lethality, Synthetic Growth Defect
BRE1 YDL074C E3 ubiquitin ligase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BNI1 YNL271C Formin genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
DNA2 YHR164C ATP-dependent 5'-flap endonuclease and DNA helicase genetic 2 1 1 Negative Genetic, Negative Genetic
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GET1 YGL020C Subunit of the GET complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
GET2 YER083C Subunit of the GET complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DUN1 YDL101C Cell-cycle checkpoint S/T protein kinase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
SLX5 YDL013W Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN4 YDL020C Transcription factor that stimulates expression of proteasome genes genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle genetic 2 1 1 Negative Genetic, Negative Genetic
RFC2 YJR068W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 1 1 Negative Genetic, Negative Genetic
YJR124C YJR124C Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CSM1 YCR086W Nucleolar protein that mediates homolog segregation during meiosis I genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
POL31 YJR006W Subunit of DNA polymerase delta (polymerase III) genetic 2 1 1 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PDR1 YGL013C Transcription factor that regulates the pleiotropic drug response regulation 1 1 1 DNA to cDNA expression microarray evidence
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Synthetic Growth Defect
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 1 1 1 Synthetic Growth Defect
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
PSY2 YNL201C Subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Synthetic Rescue
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
FIP1 YJR093C Subunit of cleavage polyadenylation factor (CPF) genetic 1 1 1 Negative Genetic
CTO1 YCR015C Protein required for cold tolerance genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Positive Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Synthetic Growth Defect
MOT1 YPL082C Essential protein involved in regulation of transcription genetic 1 1 1 Negative Genetic
IMG2 YCR071C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MEC1 YBR136W Genome integrity checkpoint protein and PI kinase superfamily member genetic 1 1 1 Synthetic Growth Defect
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Synthetic Growth Defect
INO80 YGL150C Nucleosome spacing factor genetic 1 1 1 Synthetic Growth Defect
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Synthetic Growth Defect
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
PTC3 YBL056W Type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Synthetic Growth Defect
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
PUP3 YER094C Beta 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
BRE2 YLR015W Subunit of COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Negative Genetic
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 1 1 1 Synthetic Growth Defect
PST2 YDR032C FMN-dependent NAD(P)H:quinone oxidoreductase genetic 1 1 1 Synthetic Rescue
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
YHR033W YHR033W Putative protein of unknown function physical 1 1 1 Affinity Capture-MS
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage physical 1 1 1 Two-hybrid
RLF2 YPR018W Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) genetic 1 1 1 Phenotypic Enhancement
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 1 1 1 Phenotypic Enhancement
SIR3 YLR442C Silencing protein genetic 1 1 1 Synthetic Rescue
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 1 1 1 Negative Genetic
RTT105 YER104W Chaperone for Replication Protein A complex (RPA) genetic 1 1 1 Negative Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Negative Genetic
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Negative Genetic
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Negative Genetic
UBC9 YDL064W SUMO-conjugating enzyme involved in the Smt3p conjugation pathway genetic 1 1 1 Synthetic Lethality
SRF1 YDL133W Regulator of phospholipase D (Spo14p) genetic 1 1 1 Negative Genetic
YFH1 YDL120W Mitochondrial matrix iron chaperone genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
SIR2 YDL042C Conserved NAD+ dependent histone deacetylase of the Sirtuin family genetic 1 1 1 Synthetic Growth Defect
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
SLX8 YER116C Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex genetic 1 1 1 Synthetic Growth Defect
RML2 YEL050C Mitochondrial ribosomal protein of the large subunit (L2) genetic 1 1 1 Synthetic Growth Defect
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Growth Defect
STP22 YCL008C Component of the ESCRT-I complex genetic 1 1 1 Synthetic Growth Defect
VAC7 YNL054W Integral vacuolar membrane protein genetic 1 1 1 Synthetic Growth Defect
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate genetic 1 1 1 Synthetic Growth Defect
RNR4 YGR180C Ribonucleotide-diphosphate reductase (RNR) small subunit genetic 1 1 1 Synthetic Lethality
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Synthetic Lethality
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Synthetic Lethality
SIZ1 YDR409W SUMO E3 ligase genetic 1 1 1 Phenotypic Suppression
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Synthetic Growth Defect
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Phenotypic Suppression
RFS1 YBR052C Protein of unknown function genetic 1 1 1 Synthetic Rescue
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Synthetic Growth Defect
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Synthetic Growth Defect
YBR138C YBR138C Cytoplasmic protein of unknown function genetic 1 1 1 Positive Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Positive Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 1 1 1 Positive Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
RPT6 YGL048C ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Negative Genetic
RFA3 YJL173C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
RPN8 YOR261C Essential non-ATPase regulatory subunit of the 26S proteasome genetic 1 1 1 Negative Genetic
RPT1 YKL145W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
YBL081W YBL081W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
SYN8 YAL014C Endosomal SNARE related to mammalian syntaxin 8 genetic 1 1 1 Negative Genetic
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Negative Genetic
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Negative Genetic
YBR259W YBR259W Protein of unknown function genetic 1 1 1 Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
YCL049C YCL049C Protein of unknown function genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
RIM1 YCR028C-A ssDNA-binding protein essential for mitochondrial genome maintenance genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Negative Genetic
YIL165C YIL165C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
YKL069W YKL069W Methionine-R-sulfoxide reductase genetic 1 1 1 Negative Genetic
RIM9 YMR063W Plasma membrane protein of unknown function genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
YOR131C YOR131C Putative haloacid dehalogenase-like hydrolase genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
THI73 YLR004C Putative plasma membrane permease genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
YMR310C YMR310C Putative methyltransferase genetic 1 1 1 Negative Genetic
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
THI22 YPR121W Protein with similarity to hydroxymethylpyrimidine phosphate kinases genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
UFD4 YKL010C Ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
RAD59 YDL059C Protein involved DNA double-strand break repair genetic 1 1 1 Negative Genetic
SHU2 YDR078C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 1 1 1 Positive Genetic
RAD61 YDR014W Subunit of a complex that inhibits sister chromatid cohesion genetic 1 1 1 Negative Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Synthetic Rescue
RAD24 YER173W Checkpoint protein genetic 1 1 1 Phenotypic Suppression
EPT1 YHR123W sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase genetic 1 1 1 Positive Genetic
HMG2 YLR450W HMG-CoA reductase genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Phenotypic Suppression
LIF1 YGL090W Component of the DNA ligase IV complex genetic 1 1 1 Synthetic Rescue
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Synthetic Growth Defect
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Positive Genetic
CDH1 YGL003C Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Synthetic Growth Defect
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 1 1 1 Synthetic Lethality
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 1 1 1 Negative Genetic
ADE8 YDR408C Phosphoribosyl-glycinamide transformylase genetic 1 1 1 Negative Genetic
HCS1 YKL017C Hexameric DNA polymerase alpha-associated DNA helicase A genetic 1 1 1 Positive Genetic
CTL1 YMR180C RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm genetic 1 1 1 Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
DOC1 YGL240W Processivity factor genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Synthetic Growth Defect
IES6 YEL044W Component of the INO80 chromatin remodeling complex genetic 1 1 1 Synthetic Growth Defect
MCM1 YMR043W Transcription factor genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Synthetic Lethality
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
MDV1 YJL112W Peripheral protein of cytosolic face of mitochondrial outer membrane genetic 1 1 1 Negative Genetic
ORC5 YNL261W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Synthetic Lethality
PRI1 YIR008C Subunit of DNA primase genetic 1 1 1 Negative Genetic
MFA2 YNL145W Mating pheromone a-factor genetic 1 1 1 Negative Genetic
BCS1 YDR375C Protein translocase and chaperone required for Complex III assembly genetic 1 1 1 Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Synthetic Lethality
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Negative Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Negative Genetic
PSY3 YLR376C Component of Shu complex (aka PCSS complex) physical 1 1 1 Affinity Capture-Western
HYR1 YIR037W Glutathione peroxidase genetic 1 1 1 Negative Genetic
RAD30 YDR419W DNA polymerase eta genetic 1 1 1 Synthetic Growth Defect
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Synthetic Growth Defect
ADE12 YNL220W Adenylosuccinate synthase genetic 1 1 1 Negative Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
PRI2 YKL045W Subunit of DNA primase genetic 1 1 1 Negative Genetic
PDX3 YBR035C Pyridoxine (pyridoxamine) phosphate oxidase genetic 1 1 1 Negative Genetic
NEJ1 YLR265C DNA end-binding protein required for nonhomologous end joining (NHEJ) genetic 1 1 1 Synthetic Rescue
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
ALO1 YML086C D-Arabinono-1,4-lactone oxidase genetic 1 1 1 Negative Genetic
EST2 YLR318W Reverse transcriptase subunit of the telomerase holoenzyme genetic 1 1 1 Synthetic Growth Defect
MET7 YOR241W Folylpolyglutamate synthetase genetic 1 1 1 Negative Genetic
PTR2 YKR093W Integral membrane peptide transporter genetic 1 1 1 Negative Genetic
MSP1 YGR028W Highly-conserved N-terminally anchored AAA-ATPase genetic 1 1 1 Negative Genetic
COX23 YHR116W Protein that functions in mitochondrial copper homeostasis genetic 1 1 1 Negative Genetic
DAK1 YML070W Dihydroxyacetone kinase genetic 1 1 1 Negative Genetic
FLO9 YAL063C Lectin-like protein with similarity to Flo1p genetic 1 1 1 Negative Genetic
MRM2 YGL136C Mitochondrial 2' O-ribose methyltransferase genetic 1 1 1 Positive Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
PIF1 YML061C DNA helicase, potent G-quadruplex DNA binder/unwinder genetic 1 1 1 Synthetic Rescue
AIM10 YER087W Protein with similarity to tRNA synthetases genetic 1 1 1 Synthetic Growth Defect
HEM4 YOR278W Uroporphyrinogen III synthase genetic 1 1 1 Negative Genetic
PRY3 YJL078C GPI-anchored cell wall protein involved in export of sterols genetic 1 1 1 Negative Genetic