Standard name Systematic name Name description Description
PSY3 YLR376C Component of Shu complex (aka PCSS complex) Component of Shu complex (aka PCSS complex); Shu complex also includes Shu1, Csm2, Shu2, and promotes error-free DNA repair; promotes Rad51p filament assembly; Shu complex mediates inhibition of Srs2p function; Psy3p and Csm2p contain similar DNA-binding regions which work together to form a single DNA binding site; deletion of PSY3 results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C
Visualize the interactome of PSY3
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 57

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.914 0.763 0.967
Vac/Vac Memb 0.057 0.066 NaN
Mito NaN 0.184 NaN

GFP localization & abundance

GFP localization GFP abundance
cytoplasm, nucleus 876

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PSY3 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) physical 14 5 9 Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Co-purification, Co-crystal Structure, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Co-purification, Affinity Capture-Western, Two-hybrid, Reconstituted Complex
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 7 3 7 Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Positive Genetic, Synthetic Rescue, Positive Genetic, Positive Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) physical 5 3 4 Two-hybrid, Two-hybrid, Affinity Capture-Western, Two-hybrid, Reconstituted Complex
SHU2 YDR078C Component of Shu complex (aka PCSS complex) physical 5 3 4 Two-hybrid, Two-hybrid, Co-crystal Structure, Reconstituted Complex, Two-hybrid
SRS2 YJL092W DNA helicase and DNA-dependent ATPase genetic 4 2 4 Synthetic Rescue, Positive Genetic, Synthetic Rescue, Positive Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 4 2 3 Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement
SLX4 YLR135W Endonuclease involved in processing DNA genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RIM15 YFL033C Protein kinase involved in cell proliferation in response to nutrients genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 3 2 3 Negative Genetic, Synthetic Rescue, Negative Genetic
MAG1 YER142C 3-methyl-adenine DNA glycosylase genetic 3 2 2 Negative Genetic, Synthetic Growth Defect, Negative Genetic
PAC11 YDR488C Dynein intermediate chain, microtubule motor protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 2 2 Negative Genetic, Phenotypic Suppression
RAD51 YER095W Strand exchange protein physical 2 2 2 Reconstituted Complex, Affinity Capture-Western
RAD18 YCR066W E3 ubiquitin ligase genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
REV3 YPL167C Catalytic subunit of DNA polymerase zeta genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CSM2 YIL132C Subunit of the Shu complex (aka PCSS complex) genetic 2 1 2 Positive Genetic, Positive Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SHU1 YHL006C Component of Shu complex (aka PCSS complex) genetic 2 1 2 Positive Genetic, Positive Genetic
SHU2 YDR078C Component of Shu complex (aka PCSS complex) genetic 2 1 2 Positive Genetic, Positive Genetic
STE50 YCL032W Adaptor protein for various signaling pathways genetic 2 1 2 Negative Genetic, Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 2 1 2 Negative Genetic, Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 2 1 1 Negative Genetic, Negative Genetic
VAM7 YGL212W Vacuolar SNARE protein genetic 2 1 1 Negative Genetic, Negative Genetic
TEL1 YBL088C Protein kinase primarily involved in telomere length regulation genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Synthetic Growth Defect
PIN4 YBL051C Protein involved in G2/M phase progression and response to DNA damage genetic 1 1 1 Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion genetic 1 1 1 Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Positive Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Positive Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein physical 1 1 1 Two-hybrid
CST6 YIL036W Basic leucine zipper (bZIP) transcription factor from ATF/CREB family genetic 1 1 1 Negative Genetic
GPR1 YDL035C Plasma membrane G protein coupled receptor (GPCR) genetic 1 1 1 Positive Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Positive Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 1 1 1 Negative Genetic
RAD51 YER095W Strand exchange protein genetic 1 1 1 Positive Genetic
RAD55 YDR076W Protein that stimulates strand exchange physical 1 1 1 Affinity Capture-Western
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) physical 1 1 1 Affinity Capture-Western
RAD52 YML032C Protein involved in homologous recombination physical 1 1 1 Reconstituted Complex
RAD52 YML032C Protein involved in homologous recombination genetic 1 1 1 Negative Genetic
VTS1 YOR359W Flap-structured DNA-binding and RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Phenotypic Enhancement
RAD24 YER173W Checkpoint protein genetic 1 1 1 Phenotypic Enhancement
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Negative Genetic
SPT3 YDR392W Subunit of the SAGA and SAGA-like transcriptional regulatory complexes genetic 1 1 1 Negative Genetic
TSA1 YML028W Thioredoxin peroxidase genetic 1 1 1 Negative Genetic
SAW1 YAL027W 5'- and 3'-flap DNA binding protein genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Synthetic Growth Defect
SNT1 YCR033W Set3C histone deacetylase scaffold genetic 1 1 1 Synthetic Growth Defect
ZRT1 YGL255W High-affinity zinc transporter of the plasma membrane genetic 1 1 1 Negative Genetic
TEF4 YKL081W Gamma subunit of translational elongation factor eEF1B genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Synthetic Rescue
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Positive Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 1 1 1 Positive Genetic
RMI1 YPL024W Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
SMC4 YLR086W Subunit of the condensin complex genetic 1 1 1 Negative Genetic
SLM5 YCR024C Mitochondrial asparaginyl-tRNA synthetase genetic 1 1 1 Negative Genetic
VAM3 YOR106W Syntaxin-like vacuolar t-SNARE genetic 1 1 1 Negative Genetic
YOL162W YOL162W Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPL33B YOR234C Ribosomal 60S subunit protein L33B genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase genetic 1 1 1 Synthetic Rescue
RAD5 YLR032W DNA helicase/Ubiquitin ligase genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Negative Genetic
ATG33 YLR356W Mitochondrial mitophagy-specific protein genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
DEG1 YFL001W tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
HMX1 YLR205C ER localized heme oxygenase genetic 1 1 1 Negative Genetic