Standard name Systematic name Name description Description
DST1 YGL043W General transcription elongation factor TFIIS General transcription elongation factor TFIIS; enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites; maintains RNAPII elongation activity on ribosomal protein genes during conditions of transcriptional stress
Visualize the interactome of DST1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Nucleolus 0.318 NaN 0.500
Nucleus 0.941 NaN 0.833

GFP localization & abundance

GFP localization GFP abundance
nucleus 6260

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
DST1 23 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 8 3 7 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 8 3 7 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Phenotypic Enhancement, Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 physical 8 4 6 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-MS
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 7 6 7 Dosage Rescue, Synthetic Lethality, Phenotypic Enhancement, Synthetic Lethality, Synthetic Rescue, Negative Genetic, Phenotypic Suppression
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 7 3 6 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 7 2 6 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 6 4 6 Negative Genetic, Negative Genetic, Synthetic Rescue, Synthetic Growth Defect, Synthetic Lethality, Negative Genetic
RAD51 YER095W Strand exchange protein genetic 6 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 6 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SOH1 YGL127C Subunit of the RNA polymerase II mediator complex genetic 6 4 5 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic, Synthetic Growth Defect
SWC3 YAL011W Protein of unknown function genetic 6 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
RPB4 YJL140W RNA polymerase II subunit B32 genetic 6 2 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Synthetic Rescue, Synthetic Lethality
CDC73 YLR418C Component of the Paf1p complex genetic 5 3 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
RAD52 YML032C Protein involved in homologous recombination genetic 5 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
RTT109 YLL002W Histone acetyltransferase genetic 5 2 5 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RPB9 YGL070C RNA polymerase II subunit B12.6 genetic 5 5 4 Dosage Rescue, Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue
SWC5 YBR231C Component of the SWR1 complex genetic 5 2 4 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 5 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPT4 YGR063C Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 4 3 4 Phenotypic Enhancement, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Lethality
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 4 3 4 Phenotypic Enhancement, Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
BRE1 YDL074C E3 ubiquitin ligase genetic 4 2 4 Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit genetic 4 2 4 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
SPN1 YPR133C Protein involved in RNA polymerase II transcription genetic 4 2 4 Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
ASF1 YJL115W Nucleosome assembly factor genetic 4 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
MED7 YOL135C Subunit of the RNA polymerase II mediator complex genetic 4 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SIN4 YNL236W Subunit of the RNA polymerase II mediator complex genetic 3 3 3 Synthetic Growth Defect, Negative Genetic, Positive Genetic
VPS75 YNL246W NAP family histone chaperone genetic 3 3 3 Negative Genetic, Synthetic Growth Defect, Positive Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 genetic 3 2 3 Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect
RPB9 YGL070C RNA polymerase II subunit B12.6 physical 3 2 3 Affinity Capture-MS, PCA, PCA
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation genetic 3 2 3 Synthetic Lethality, Synthetic Lethality, Negative Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 3 2 3 Negative Genetic, Synthetic Growth Defect, Negative Genetic
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 3 2 3 Positive Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SDC1 YDR469W Subunit of the COMPASS (Set1C) complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTT101 YJL047C Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MMS1 YPR164W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MMS22 YLR320W Subunit of E3 ubiquitin ligase complex involved in replication repair genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RCO1 YMR075W Essential component of the Rpd3S histone deacetylase complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SKI3 YPR189W Ski complex component and TPR protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 3 3 2 Synthetic Lethality, Positive Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect
HHT1 YBR010W Histone H3 genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Rescue
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 3 2 2 Synthetic Lethality, Negative Genetic, Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 3 2 2 Synthetic Lethality, Synthetic Lethality, Positive Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MED8 YBR193C Subunit of the RNA polymerase II mediator complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 3 2 1 Positive Genetic, Negative Genetic, Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 physical 2 2 2 Affinity Capture-MS, Reconstituted Complex
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex genetic 2 2 2 Positive Genetic, Synthetic Growth Defect
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SET2 YJL168C Histone methyltransferase with a role in transcriptional elongation genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
HPR1 YDR138W Subunit of THO/TREX complexes genetic 2 2 2 Synthetic Rescue, Negative Genetic
SRC1 YML034W Inner nuclear membrane protein genetic 2 2 2 Phenotypic Enhancement, Negative Genetic
GCD11 YER025W Gamma subunit of the translation initiation factor eIF2 genetic 2 2 2 Phenotypic Suppression, Positive Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 2 2 2 Negative Genetic, Positive Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 2 2 Negative Genetic, Synthetic Rescue
RTR1 YER139C Dual specificity protein phosphatase genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
GGA2 YHR108W Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
SNG1 YGR197C Protein involved in resistance to nitrosoguanidine and 6-azauracil genetic 2 2 2 Dosage Rescue, Negative Genetic
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 2 2 2 Synthetic Growth Defect, Phenotypic Suppression
SCH9 YHR205W AGC family protein kinase genetic 2 2 2 Phenotypic Suppression, Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 2 2 2 Negative Genetic, Positive Genetic
RFC5 YBR087W Subunit of heteropentameric Replication factor C (RF-C) genetic 2 2 2 Positive Genetic, Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 2 2 2 Positive Genetic, Phenotypic Suppression
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
TUB4 YLR212C Gamma-tubulin genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
BUR2 YLR226W Cyclin for the Sgv1p (Bur1p) protein kinase genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 2 2 Negative Genetic, Positive Genetic
CTK3 YML112W Gamma subunit of C-terminal domain kinase I genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 2 2 2 Synthetic Rescue, Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
RPB5 YBR154C RNA polymerase subunit ABC27 physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 2 1 2 Positive Genetic, Positive Genetic
RPB3 YIL021W RNA polymerase II third largest subunit B44 genetic 2 1 2 Negative Genetic, Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
LEO1 YOR123C Component of the Paf1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAD6 YGL058W Ubiquitin-conjugating enzyme (E2) genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
TAF14 YPL129W Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes genetic 2 1 2 Synthetic Lethality, Synthetic Lethality
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
GCR2 YNL199C Transcriptional activator of genes involved in glycolysis genetic 2 1 2 Negative Genetic, Negative Genetic
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 2 1 2 Negative Genetic, Negative Genetic
RAD54 YGL163C DNA-dependent ATPase that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
MED1 YPR070W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAD55 YDR076W Protein that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
LSM6 YDR378C Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 2 1 2 Negative Genetic, Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 2 1 2 Negative Genetic, Negative Genetic
HPC2 YBR215W Subunit of the HIR complex genetic 2 1 2 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
RAD50 YNL250W Subunit of MRX complex with Mre11p and Xrs2p genetic 2 1 2 Negative Genetic, Negative Genetic
XRS2 YDR369C FHA domain-containing component of the Mre11 complex genetic 2 1 2 Negative Genetic, Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 1 2 Negative Genetic, Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 2 1 2 Positive Genetic, Positive Genetic
LSM3 YLR438C-A Lsm (Like Sm) protein genetic 2 1 2 Negative Genetic, Negative Genetic
LCP5 YER127W Essential protein involved in maturation of 18S rRNA genetic 2 1 2 Positive Genetic, Positive Genetic
SUS1 YBR111W-A Global transcriptional regulator, component of SAGA, TREX-2 complexes genetic 2 1 2 Negative Genetic, Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
YDR131C YDR131C F-box protein subunit of SCF ubiquitin ligase complex genetic 2 1 2 Negative Genetic, Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 2 1 2 Negative Genetic, Negative Genetic
SPS2 YDR522C Protein expressed during sporulation genetic 2 1 2 Negative Genetic, Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 2 1 2 Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
VID28 YIL017C GID Complex subunit, serves as adaptor for regulatory subunit Vid24p genetic 2 1 2 Negative Genetic, Negative Genetic
PTK1 YKL198C Putative serine/threonine protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
RIM13 YMR154C Calpain-like cysteine protease genetic 2 1 2 Negative Genetic, Negative Genetic
YSP3 YOR003W Putative precursor of the subtilisin-like protease III genetic 2 1 2 Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 2 1 2 Negative Genetic, Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 2 1 2 Negative Genetic, Negative Genetic
NPR1 YNL183C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
SPC24 YMR117C Component of the kinetochore-associated Ndc80 complex genetic 2 1 2 Negative Genetic, Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 2 1 2 Negative Genetic, Negative Genetic
MUS81 YDR386W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 2 1 2 Negative Genetic, Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 2 1 2 Negative Genetic, Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 2 1 2 Negative Genetic, Negative Genetic
LSM12 YHR121W Protein of unknown function that may function in RNA processing genetic 2 1 2 Negative Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 2 1 2 Negative Genetic, Negative Genetic
BET2 YPR176C Beta subunit of Type II geranylgeranyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 2 1 2 Synthetic Growth Defect, Synthetic Growth Defect
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
BCY1 YIL033C Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA) genetic 2 1 2 Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Negative Genetic, Negative Genetic
DFG16 YOR030W Probable multiple transmembrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex physical 2 2 1 Two-hybrid, Affinity Capture-Western
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex physical 2 2 1 Two-hybrid, Affinity Capture-Western
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 2 2 1 Positive Genetic, Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 2 2 1 Positive Genetic, Negative Genetic
UTP21 YLR409C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 2 2 1 Positive Genetic, Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 2 2 1 Positive Genetic, Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 2 2 1 Positive Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
NMD5 YJR132W Karyopherin physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
HSP78 YDR258C Oligomeric mitochondrial matrix chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 2 1 1 Affinity Capture-MS, Affinity Capture-MS
MOT2 YER068W Ubiquitin-protein ligase subunit of the CCR4-NOT complex physical 2 1 1 Reconstituted Complex, Reconstituted Complex
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
PUF6 YDR496C Pumilio-homology domain protein genetic 2 1 1 Positive Genetic, Positive Genetic
TAF12 YDR145W Subunit (61/68 kDa) of TFIID and SAGA complexes genetic 2 1 1 Negative Genetic, Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
TAF13 YML098W TFIID subunit (19 kDa) genetic 2 1 1 Negative Genetic, Negative Genetic
PFY1 YOR122C Profilin genetic 2 1 1 Negative Genetic, Negative Genetic
MED4 YOR174W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 2 1 1 Negative Genetic, Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 2 1 1 Negative Genetic, Negative Genetic
ADA2 YDR448W Transcription coactivator genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP1 YML007W Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
YAP5 YIR018W Basic leucine zipper (bZIP) iron-sensing transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
INO4 YOL108C Transcription factor involved in phospholipid synthesis regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator regulation 1 1 1 DNA to cDNA expression microarray evidence
DED81 YHR019C Cytosolic asparaginyl-tRNA synthetase genetic 1 1 1 Positive Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Positive Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
ARP7 YPR034W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 1 1 1 Negative Genetic
DST1 YGL043W General transcription elongation factor TFIIS physical 1 1 1 Affinity Capture-MS
POL5 YEL055C Protein involved in 60S assembly and pre-40S AFs recycling physical 1 1 1 Affinity Capture-MS
SPT5 YML010W Spt4p/5p (DSIF) transcription elongation factor complex subunit physical 1 1 1 Affinity Capture-MS
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 1 1 1 Synthetic Growth Defect
SSN2 YDR443C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex physical 1 1 1 Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes physical 1 1 1 Affinity Capture-Western
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes genetic 1 1 1 Negative Genetic
SPT7 YBR081C Subunit of the SAGA transcriptional regulatory complex physical 1 1 1 Affinity Capture-Western
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit physical 1 1 1 Co-purification
TFG2 YGR005C TFIIF (Transcription Factor II) middle subunit genetic 1 1 1 Negative Genetic
RPB11 YOL005C RNA polymerase II subunit B12.5 physical 1 1 1 Affinity Capture-MS
RPB11 YOL005C RNA polymerase II subunit B12.5 genetic 1 1 1 Negative Genetic
HAA1 YPR008W Transcriptional activator involved in adaptation to weak acid stress physical 1 1 1 Affinity Capture-MS
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
HOG1 YLR113W Mitogen-activated protein kinase involved in osmoregulation physical 1 1 1 Affinity Capture-Western
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions physical 1 1 1 Affinity Capture-MS
GCN2 YDR283C Protein kinase physical 1 1 1 Reconstituted Complex
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Reconstituted Complex
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Two-hybrid
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones genetic 1 1 1 Synthetic Lethality
SMT3 YDR510W Ubiquitin-like protein of the SUMO family physical 1 1 1 PCA
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation physical 1 1 1 Reconstituted Complex
POP2 YNR052C Subunit of Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation genetic 1 1 1 Synthetic Growth Defect
RPC82 YPR190C RNA polymerase III subunit C82 physical 1 1 1 Affinity Capture-MS
PAF1 YBR279W Component of the Paf1p complex involved in transcription elongation physical 1 1 1 Reconstituted Complex
LEO1 YOR123C Component of the Paf1 complex physical 1 1 1 Reconstituted Complex
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
SPT6 YGR116W Nucleosome remodeling protein genetic 1 1 1 Synthetic Growth Defect
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 1 1 1 Synthetic Lethality
PEA2 YER149C Coiled-coil 12S polarisome subunit genetic 1 1 1 Synthetic Lethality
PET122 YER153C Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Synthetic Lethality
SNF2 YOR290C Catalytic subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Synthetic Lethality
SPI1 YER150W GPI-anchored cell wall protein involved in weak acid resistance genetic 1 1 1 Synthetic Lethality
SPT15 YER148W TATA-binding protein (TBP) genetic 1 1 1 Synthetic Lethality
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Synthetic Lethality
UBC12 YLR306W Enzyme that mediates the conjugation of Rub1p genetic 1 1 1 Synthetic Lethality
SIT1 YEL065W Ferrioxamine B transporter genetic 1 1 1 Synthetic Lethality
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers genetic 1 1 1 Synthetic Rescue
SDT1 YGL224C Pyrimidine nucleotidase genetic 1 1 1 Dosage Rescue
MFT1 YML062C Subunit of the THO complex genetic 1 1 1 Synthetic Rescue
RRP6 YOR001W Nuclear exosome exonuclease component genetic 1 1 1 Synthetic Rescue
FYV4 YHR059W Protein of unknown function genetic 1 1 1 Synthetic Growth Defect
SRB5 YGR104C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Synthetic Lethality
LGE1 YPL055C Protein involved in histone H2B ubiquitination genetic 1 1 1 Synthetic Lethality
SWD1 YAR003W Subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Lethality
SWD3 YBR175W Essential subunit of the COMPASS (Set1C) complex genetic 1 1 1 Synthetic Lethality
TFG1 YGR186W TFIIF (Transcription Factor II) largest subunit genetic 1 1 1 Synthetic Lethality
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase genetic 1 1 1 Phenotypic Enhancement
MAD1 YGL086W Coiled-coil protein involved in spindle-assembly checkpoint genetic 1 1 1 Phenotypic Enhancement
RSC1 YGR056W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Negative Genetic
PFD1 YJL179W Subunit of heterohexameric prefoldin genetic 1 1 1 Negative Genetic
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes genetic 1 1 1 Negative Genetic
RAD17 YOR368W Checkpoint protein genetic 1 1 1 Phenotypic Suppression
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
HAT2 YEL056W Subunit of the Hat1p-Hat2p histone acetyltransferase complex genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
ESC8 YOL017W Protein involved in telomeric and mating-type locus silencing genetic 1 1 1 Negative Genetic
VPS64 YDR200C Protein required for cytoplasm to vacuole targeting of proteins genetic 1 1 1 Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 1 1 1 Negative Genetic
RAD3 YER171W 5' to 3' DNA helicase genetic 1 1 1 Negative Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Negative Genetic
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
PAC10 YGR078C Part of the heteromeric co-chaperone GimC/prefoldin complex genetic 1 1 1 Negative Genetic
MMS4 YBR098W Subunit of structure-specific Mms4p-Mus81p endonuclease genetic 1 1 1 Negative Genetic
TAF6 YGL112C Subunit (60 kDa) of TFIID and SAGA complexes genetic 1 1 1 Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 1 1 1 Negative Genetic
SRB8 YCR081W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Positive Genetic
RAD2 YGR258C Single-stranded DNA endonuclease genetic 1 1 1 Phenotypic Enhancement
SLS1 YLR139C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
TSR2 YLR435W Protein with a potential role in pre-rRNA processing genetic 1 1 1 Negative Genetic
GCD14 YJL125C Subunit of tRNA (1-methyladenosine) methyltransferase genetic 1 1 1 Negative Genetic
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
STO1 YMR125W Large subunit of the nuclear mRNA cap-binding protein complex genetic 1 1 1 Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
RIE1 YGR250C RNA binding protein and negative regulator of START genetic 1 1 1 Positive Genetic
TIF4631 YGR162W Translation initiation factor eIF4G and scaffold protein genetic 1 1 1 Positive Genetic
SUB1 YMR039C Transcriptional regulator genetic 1 1 1 Synthetic Rescue
IMD2 YHR216W Inosine monophosphate dehydrogenase genetic 1 1 1 Dosage Rescue
RTT106 YNL206C Histone chaperone genetic 1 1 1 Synthetic Growth Defect
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
ERV15 YBR210W Protein involved in export of proteins from the endoplasmic reticulum genetic 1 1 1 Positive Genetic
YCR016W YCR016W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MPS1 YDL028C Dual-specificity kinase genetic 1 1 1 Positive Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 1 1 1 Positive Genetic
RVB1 YDR190C ATP-dependent DNA helicase, also known as pontin genetic 1 1 1 Positive Genetic
SSD1 YDR293C Translational repressor genetic 1 1 1 Negative Genetic
EFT2 YDR385W Elongation factor 2 (EF-2), also encoded by EFT1 genetic 1 1 1 Negative Genetic
SDD1 YEL057C Protein of unknown function genetic 1 1 1 Negative Genetic
UTR2 YEL040W Chitin transglycosylase genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
PRP22 YER013W DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
HXK1 YFR053C Hexokinase isoenzyme 1 genetic 1 1 1 Negative Genetic
RKR1 YMR247C RING domain E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
ERP5 YHR110W Protein with similarity to Emp24p and Erv25p genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Positive Genetic
TAF8 YML114C TFIID subunit (65 kDa) genetic 1 1 1 Negative Genetic
PAH1 YMR165C Mg2+-dependent phosphatidate (PA) phosphatase genetic 1 1 1 Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Positive Genetic
TCO89 YPL180W Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p) genetic 1 1 1 Negative Genetic
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Negative Genetic
HTA1 YDR225W Histone H2A genetic 1 1 1 Positive Genetic
HTB1 YDR224C Histone H2B genetic 1 1 1 Positive Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Growth Defect
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
UBP8 YMR223W Ubiquitin-specific protease component of the SAGA acetylation complex genetic 1 1 1 Synthetic Rescue
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Synthetic Growth Defect
VIP1 YLR410W Bifunctional inositol pyrophosphate kinase and phosphatase genetic 1 1 1 Synthetic Growth Defect
SGF73 YGL066W Subunit of DUBm module of SAGA and SLIK genetic 1 1 1 Synthetic Growth Defect
HHT2 YNL031C Histone H3 genetic 1 1 1 Synthetic Rescue
NUP84 YDL116W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 1 1 1 Synthetic Lethality
MVP1 YMR004W Protein required for sorting proteins to the vacuole genetic 1 1 1 Synthetic Rescue
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
RPL40A YIL148W Ubiquitin-ribosomal 60S subunit protein L40A fusion protein genetic 1 1 1 Phenotypic Suppression
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes genetic 1 1 1 Phenotypic Suppression
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Negative Genetic
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation genetic 1 1 1 Synthetic Lethality
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
NOT5 YPR072W Component of the CCR4-NOT core complex, involved in mRNA decapping genetic 1 1 1 Synthetic Growth Defect
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Positive Genetic
PBN1 YCL052C Component of glycosylphosphatidylinositol-mannosyltransferase I genetic 1 1 1 Positive Genetic
LCB2 YDR062W Component of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
SPB4 YFL002C Putative ATP-dependent RNA helicase genetic 1 1 1 Positive Genetic
RIX1 YHR197W Component of the Rix1 complex and possibly pre-replicative complexes genetic 1 1 1 Positive Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Positive Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
RLP24 YLR009W Essential protein required for ribosomal large subunit biogenesis genetic 1 1 1 Positive Genetic
RPL10 YLR075W Ribosomal 60S subunit protein L10 genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Positive Genetic
TRS130 YMR218C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Positive Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Positive Genetic
RIO2 YNL207W Essential serine kinase involved in the processing of 20S pre-rRNA genetic 1 1 1 Positive Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Positive Genetic
RIO1 YOR119C Serine kinase involved in cell cycle regulation and rDNA integrity genetic 1 1 1 Positive Genetic
SME1 YOR159C Core Sm protein Sm E genetic 1 1 1 Positive Genetic
RPA43 YOR340C RNA polymerase I subunit A43 genetic 1 1 1 Positive Genetic
RPA190 YOR341W RNA polymerase I largest subunit A190 genetic 1 1 1 Positive Genetic
SMX3 YPR182W Core Sm protein Sm F genetic 1 1 1 Positive Genetic
QDR3 YBR043C Multidrug transporter of the major facilitator superfamily genetic 1 1 1 Positive Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Positive Genetic
UMP1 YBR173C Chaperone required for correct maturation of the 20S proteasome genetic 1 1 1 Positive Genetic
GDT1 YBR187W Calcium and manganese transporter with higher affinity for Ca2+ genetic 1 1 1 Positive Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex genetic 1 1 1 Positive Genetic
MYG1 YER156C Protein involved in mitochondrial function genetic 1 1 1 Positive Genetic
LSB3 YFR024C-A Protein containing a C-terminal SH3 domain genetic 1 1 1 Positive Genetic
YLL032C YLL032C Protein of unknown function genetic 1 1 1 Positive Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Positive Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Positive Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Positive Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Positive Genetic
SIM1 YIL123W Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) genetic 1 1 1 Positive Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Positive Genetic
YJL132W YJL132W Putative protein of unknown function genetic 1 1 1 Positive Genetic
NTA1 YJR062C Amidase genetic 1 1 1 Positive Genetic
HMS2 YJR147W Protein with similarity to heat shock transcription factors genetic 1 1 1 Positive Genetic
TCD2 YKL027W tRNA threonylcarbamoyladenosine dehydratase genetic 1 1 1 Positive Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Positive Genetic
PML1 YLR016C Subunit of the RES complex genetic 1 1 1 Positive Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Positive Genetic
JLP2 YMR132C Protein of unknown function genetic 1 1 1 Positive Genetic
RPL9B YNL067W Ribosomal 60S subunit protein L9B genetic 1 1 1 Positive Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Positive Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Positive Genetic
RPA49 YNL248C RNA polymerase I subunit A49 genetic 1 1 1 Positive Genetic
LPL1 YOR059C Phospholipase genetic 1 1 1 Positive Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Positive Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Positive Genetic
MMT2 YPL224C Putative metal transporter involved in mitochondrial iron accumulation genetic 1 1 1 Positive Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
FAD1 YDL045C Flavin adenine dinucleotide (FAD) synthetase genetic 1 1 1 Negative Genetic
TSR1 YDL060W Protein required for processing of 20S pre-rRNA in the cytoplasm genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
HEM1 YDR232W 5-aminolevulinate synthase genetic 1 1 1 Negative Genetic
UTP4 YDR324C Subunit of U3-containing 90S preribosome and SSU processome complexes genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
RPP1 YHR062C Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
ERG7 YHR072W Lanosterol synthase genetic 1 1 1 Negative Genetic
ORC6 YHR118C Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
UTP25 YIL091C Nucleolar protein genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
MSL5 YLR116W Component of commitment complex genetic 1 1 1 Negative Genetic
MAS1 YLR163C Beta subunit of the mitochondrial processing protease (MPP) genetic 1 1 1 Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
RRB1 YMR131C Specific assembly chaperone for ribosomal protein Rpl3p genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
RPC31 YNL151C RNA polymerase III subunit C31 genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Negative Genetic
POP3 YNL282W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RFA2 YNL312W Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
WRS1 YOL097C Cytoplasmic tryptophanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Negative Genetic
GLN4 YOR168W Glutamine tRNA synthetase genetic 1 1 1 Negative Genetic
RPB10 YOR210W RNA polymerase subunit ABC10-beta genetic 1 1 1 Negative Genetic
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
IDI1 YPL117C Isopentenyl diphosphate:dimethylallyl diphosphate isomerase genetic 1 1 1 Negative Genetic
SPC29 YPL124W Inner plaque spindle pole body (SPB) component genetic 1 1 1 Negative Genetic
RPL5 YPL131W Ribosomal 60S subunit protein L5 genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
TFB4 YPR056W Subunit of TFIIH complex genetic 1 1 1 Negative Genetic
MTW1 YAL034W-A Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
POL12 YBL035C B subunit of DNA polymerase alpha-primase complex genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TAF11 YML015C TFIID subunit (40 kDa) genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
SGT1 YOR057W Cochaperone protein genetic 1 1 1 Negative Genetic
TOA1 YOR194C TFIIA large subunit genetic 1 1 1 Negative Genetic
SUA7 YPR086W Transcription factor TFIIB genetic 1 1 1 Negative Genetic
YPK3 YBR028C AGC kinase genetic 1 1 1 Negative Genetic
TBS1 YBR150C Protein of unknown function genetic 1 1 1 Negative Genetic
SMP1 YBR182C MADS-box transcription factor involved in osmotic stress response genetic 1 1 1 Negative Genetic
YDL012C YDL012C Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
GPD1 YDL022W NAD-dependent glycerol-3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
HDA2 YDR295C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Negative Genetic
YSP2 YDR326C Sterol-binding protein genetic 1 1 1 Negative Genetic
PHO92 YDR374C Posttranscriptional regulator of phosphate and glucose metabolism genetic 1 1 1 Negative Genetic
QCR7 YDR529C Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
GTA1 YEL043W Protein of unknown function genetic 1 1 1 Negative Genetic
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
MXR1 YER042W Methionine-S-sulfoxide reductase genetic 1 1 1 Negative Genetic
RPL23B YER117W Ribosomal 60S subunit protein L23B genetic 1 1 1 Negative Genetic
YFR006W YFR006W Putative X-Pro aminopeptidase genetic 1 1 1 Negative Genetic
IRC7 YFR055W Cysteine desulphydrase, enables growth on cysteine as nitrogen source genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
RTG3 YBL103C bHLH/Zip transcription factor for retrograde (RTG) and TOR pathways genetic 1 1 1 Negative Genetic
ECM8 YBR076W Non-essential protein of unknown function genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
MKC7 YDR144C GPI-anchored aspartyl protease genetic 1 1 1 Negative Genetic
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 1 1 1 Negative Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
SKA1 YKL023W SKI complex-associated protein genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
YLR225C YLR225C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 1 1 1 Negative Genetic
MKS1 YNL076W Pleiotropic negative transcriptional regulator genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
YGR240C-A YGR240C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
YIL152W YIL152W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase genetic 1 1 1 Negative Genetic
MRPL8 YJL063C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein genetic 1 1 1 Negative Genetic
MTC2 YKL098W Protein of unknown function genetic 1 1 1 Negative Genetic
RSM22 YKL155C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
KDX1 YKL161C Protein kinase genetic 1 1 1 Negative Genetic
YKL183C-A YKL183C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
GPT2 YKR067W Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
MET1 YKR069W S-adenosyl-L-methionine uroporphyrinogen III transmethylase genetic 1 1 1 Negative Genetic
VBA5 YKR105C Plasma membrane protein of the Major Facilitator Superfamily (MFS) genetic 1 1 1 Negative Genetic
PET309 YLR067C Specific translational activator for the COX1 mRNA genetic 1 1 1 Negative Genetic
YPS1 YLR120C Aspartic protease genetic 1 1 1 Negative Genetic
ENT2 YLR206W Epsin-like protein required for endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
RIF2 YLR453C Protein that binds to the Rap1p C-terminus genetic 1 1 1 Negative Genetic
NTG1 YAL015C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Phenotypic Suppression
NTG2 YOL043C DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase genetic 1 1 1 Phenotypic Suppression
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MDM1 YML104C PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs genetic 1 1 1 Negative Genetic
YML108W YML108W Protein of unknown function genetic 1 1 1 Negative Genetic
PLB2 YMR006C Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
MSN2 YMR037C Stress-responsive transcriptional activator genetic 1 1 1 Negative Genetic
YMR084W YMR084W Putative protein of unknown function genetic 1 1 1 Negative Genetic
MTG1 YMR097C Putative GTPase peripheral to the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
YMR295C YMR295C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 1 1 1 Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 1 1 1 Negative Genetic
YNL108C YNL108C Protein phosphatase genetic 1 1 1 Negative Genetic
MRPL19 YNL185C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
VNX1 YNL321W Calcium/H+ antiporter localized to the endoplasmic reticulum membrane genetic 1 1 1 Negative Genetic
PET494 YNR045W Mitochondrial translational activator specific for the COX3 mRNA genetic 1 1 1 Negative Genetic
IFM1 YOL023W Mitochondrial translation initiation factor 2 genetic 1 1 1 Negative Genetic
YOL057W YOL057W Dipeptidyl-peptidase III genetic 1 1 1 Negative Genetic
YOL164W-A YOL164W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR032W-A YOR032W-A Protein of unknown function genetic 1 1 1 Negative Genetic
REV1 YOR346W Deoxycytidyl transferase genetic 1 1 1 Negative Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex genetic 1 1 1 Negative Genetic
YPR159C-A YPR159C-A Protein of unknown function genetic 1 1 1 Negative Genetic
ERG1 YGR175C Squalene epoxidase genetic 1 1 1 Negative Genetic
TOP3 YLR234W DNA Topoisomerase III genetic 1 1 1 Negative Genetic
URA1 YKL216W Dihydroorotate dehydrogenase genetic 1 1 1 Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 1 1 1 Negative Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
YJR096W YJR096W Xylose and arabinose reductase genetic 1 1 1 Negative Genetic
HIR1 YBL008W Subunit of the HIR complex genetic 1 1 1 Negative Genetic
SPS19 YNL202W Peroxisomal 2,4-dienoyl-CoA reductase genetic 1 1 1 Positive Genetic
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 1 1 1 Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 1 1 1 Positive Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
YPT32 YGL210W Rab family GTPase involved in the exocytic pathway genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Negative Genetic
HIR3 YJR140C Subunit of the HIR complex genetic 1 1 1 Negative Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
NUC1 YJL208C Major mitochondrial nuclease genetic 1 1 1 Negative Genetic
OCT1 YKL134C Mitochondrial intermediate peptidase genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
MET32 YDR253C Zinc-finger DNA-binding transcription factor genetic 1 1 1 Negative Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
HIR2 YOR038C Subunit of HIR nucleosome assembly complex genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
HMG2 YLR450W HMG-CoA reductase genetic 1 1 1 Positive Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Positive Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Positive Genetic
TCM62 YBR044C Protein involved in assembly of the succinate dehydrogenase complex genetic 1 1 1 Positive Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Positive Genetic
SPC3 YLR066W Subunit of signal peptidase complex genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
UBP15 YMR304W Ubiquitin-specific protease involved in protein deubiquitination genetic 1 1 1 Synthetic Rescue
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Synthetic Growth Defect
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
CDC39 YCR093W Subunit of the CCR4-NOT1 core complex physical 1 1 1 Reconstituted Complex
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Positive Genetic
AOS1 YPR180W Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CAF40 YNL288W Component of the CCR4-NOT transcriptional complex genetic 1 1 1 Synthetic Growth Defect
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Positive Genetic
DBP10 YDL031W Putative ATP-dependent RNA helicase of the DEAD-box protein family genetic 1 1 1 Negative Genetic
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
BDF2 YDL070W Protein involved in transcription initiation genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator genetic 1 1 1 Synthetic Growth Defect
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Positive Genetic
ACE2 YLR131C Transcription factor required for septum destruction after cytokinesis genetic 1 1 1 Positive Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Positive Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Positive Genetic
ASA1 YPR085C Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Negative Genetic
ATG12 YBR217W Ubiquitin-like modifier involved in autophagy and the Cvt pathway genetic 1 1 1 Negative Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Positive Genetic
DAS1 YJL149W Putative SCF ubiquitin ligase F-box protein genetic 1 1 1 Phenotypic Suppression
BUL1 YMR275C Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Positive Genetic
CIN8 YEL061C Bipolar kinesin motor protein genetic 1 1 1 Negative Genetic
AIM46 YHR199C Protein of unknown function genetic 1 1 1 Positive Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
DPB11 YJL090C DNA replication initiation protein genetic 1 1 1 Negative Genetic
CIK1 YMR198W Kinesin-associated protein genetic 1 1 1 Positive Genetic
CPR3 YML078W Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Synthetic Growth Defect
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
ADH5 YBR145W Alcohol dehydrogenase isoenzyme V genetic 1 1 1 Positive Genetic
BIT2 YBR270C Subunit of TORC2 membrane-associated complex genetic 1 1 1 Negative Genetic
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
BAS1 YKR099W Myb-related transcription factor genetic 1 1 1 Positive Genetic
CAK1 YFL029C Cyclin-dependent kinase-activating kinase genetic 1 1 1 Negative Genetic
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Phenotypic Suppression
ASK10 YGR097W Regulator of the Fps1p glycerol channel physical 1 1 1 Affinity Capture-Western
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Positive Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AMD1 YML035C AMP deaminase genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein genetic 1 1 1 Negative Genetic
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Negative Genetic
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Positive Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
CCS1 YMR038C Copper chaperone for superoxide dismutase Sod1p genetic 1 1 1 Synthetic Growth Defect
DPH6 YLR143W Diphthamide synthetase genetic 1 1 1 Negative Genetic
AZF1 YOR113W Zinc-finger transcription factor genetic 1 1 1 Negative Genetic
ADY4 YLR227C Structural component of the meiotic outer plaque genetic 1 1 1 Positive Genetic
ACM1 YPL267W Pseudosubstrate inhibitor of the APC/C genetic 1 1 1 Negative Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Positive Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Positive Genetic
DIC1 YLR348C Mitochondrial dicarboxylate carrier genetic 1 1 1 Negative Genetic
DCC1 YCL016C Subunit of a complex with Ctf8p and Ctf18p genetic 1 1 1 Negative Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Positive Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Positive Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Synthetic Growth Defect
CUZ1 YNL155W Protein with a role in the ubiquitin-proteasome pathway genetic 1 1 1 Negative Genetic
DPH5 YLR172C Methyltransferase required for synthesis of diphthamide genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Negative Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Positive Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Negative Genetic
DAL4 YIR028W Allantoin permease genetic 1 1 1 Negative Genetic
BCD1 YHR040W Essential protein required for the accumulation of box C/D snoRNA genetic 1 1 1 Negative Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 1 1 1 Positive Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Positive Genetic
AIM36 YMR157C Protein of unknown function genetic 1 1 1 Negative Genetic