| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
10 |
6 |
9 |
Dosage Rescue, Synthetic Rescue, Synthetic Rescue, Phenotypic Suppression, Synthetic Rescue, Phenotypic Suppression, Synthetic Lethality, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
9 |
5 |
7 |
Affinity Capture-Western, Reconstituted Complex, Biochemical Activity, Biochemical Activity, Biochemical Activity, Biochemical Activity, Two-hybrid, Two-hybrid, Affinity Capture-MS |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
3 |
3 |
2 |
Dosage Rescue, Synthetic Growth Defect, Negative Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
physical |
3 |
2 |
2 |
Two-hybrid, Affinity Capture-Western, Two-hybrid |
| EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Synthetic Rescue |
| SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
physical |
2 |
2 |
2 |
Two-hybrid, Biochemical Activity |
| SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
genetic |
2 |
2 |
2 |
Dosage Rescue, Positive Genetic |
| CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
| SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Negative Genetic |
| KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RPA14 |
YDR156W |
RNA polymerase I subunit A14 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKI8 |
YGL213C |
Ski complex component and WD-repeat protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| CTK2 |
YJL006C |
Beta subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC23 |
YHR166C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| NAP1 |
YKR048C |
Histone chaperone and assembly chaperone for Rps6a/b |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PTP2 |
YOR208W |
Phosphotyrosine-specific phosphatase |
genetic |
2 |
2 |
1 |
Dosage Lethality, Synthetic Rescue |
| PTP3 |
YER075C |
Phosphotyrosine-specific protein phosphatase |
genetic |
2 |
2 |
1 |
Dosage Lethality, Synthetic Rescue |
| CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
2 |
2 |
1 |
Dosage Rescue, Synthetic Lethality |
| SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
2 |
2 |
1 |
Positive Genetic, Synthetic Rescue |
| GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| SMK1 |
YPR054W |
Middle sporulation-specific mitogen-activated protein kinase (MAPK) |
regulation |
1 |
1 |
1 |
protein kinase assay evidence |
| APC2 |
YLR127C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BDF1 |
YLR399C |
BET family transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUR2 |
YLR226W |
Cyclin for the Sgv1p (Bur1p) protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG27 |
YJL178C |
Type I membrane protein involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
physical |
1 |
1 |
1 |
Biochemical Activity |
| CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
| TWF1 |
YGR080W |
Twinfilin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SIT4 |
YDL047W |
Ceramide-activated, type 2A-related serine-threonine phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| GPI1 |
YGR216C |
Membrane protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRP1 |
YNL189W |
Karyopherin alpha homolog |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KAP122 |
YGL016W |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PML39 |
YML107C |
Protein required for nuclear retention of unspliced pre-mRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PML1 |
YLR016C |
Subunit of the RES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIS11 |
YLR136C |
mRNA-binding protein expressed during iron starvation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NNT1 |
YLR285W |
S-adenosylmethionine-dependent methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POA1 |
YBR022W |
Phosphatase that is highly specific for ADP-ribose 1''-phosphate |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NGR1 |
YBR212W |
RNA binding protein that negatively regulates growth rate |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PUS2 |
YGL063W |
Mitochondrial tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YGR283C |
YGR283C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRM2 |
YKR056W |
tRNA methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNL1 |
YIL016W |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UBP8 |
YMR223W |
Ubiquitin-specific protease component of the SAGA acetylation complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RNH201 |
YNL072W |
Ribonuclease H2 catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOL1 |
YNR034W |
Protein with a possible role in tRNA export |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STP2 |
YHR006W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIP6 |
YHR015W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EDC3 |
YEL015W |
Non-essential conserved protein with a role in mRNA decapping |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLS1 |
YLR139C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRE9 |
YGR135W |
Alpha 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YJR084W |
YJR084W |
Protein that forms a complex with Thp3p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IFM1 |
YOL023W |
Mitochondrial translation initiation factor 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SWD1 |
YAR003W |
Subunit of the COMPASS (Set1C) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TPS1 |
YBR126C |
Synthase subunit of trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSL1 |
YML100W |
Large subunit of trehalose 6-phosphate synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REG1 |
YDR028C |
Regulatory subunit of type 1 protein phosphatase Glc7p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DPP1 |
YDR284C |
Diacylglycerol pyrophosphate (DGPP) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GIN4 |
YDR507C |
Protein kinase involved in bud growth and assembly of the septin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCK1 |
YGL158W |
Protein kinase involved in oxidative stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOG1 |
YHR044C |
2-deoxyglucose-6-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| KSP1 |
YHR082C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRK1 |
YIL095W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FBP1 |
YLR377C |
Fructose-1,6-bisphosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP4 |
YGL229C |
Protein required for function of the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SIC1 |
YLR079W |
Cyclin-dependent kinase inhibitor (CKI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTK3 |
YML112W |
Gamma subunit of C-terminal domain kinase I |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TUB3 |
YML124C |
Alpha-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFK27 |
YOL136C |
6-phosphofructo-2-kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CIN2 |
YPL241C |
GTPase-activating protein (GAP) for Cin4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM16 |
YPR046W |
Component of the Ctf19 complex and the COMA subcomplex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| MCM2 |
YBL023C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| POL12 |
YBL035C |
B subunit of DNA polymerase alpha-primase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CTR86 |
YCR054C |
Essential protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| REF2 |
YDR195W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCE1 |
YKL011C |
Mitochondrial cruciform cutting endonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLU7 |
YDR088C |
RNA splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA15 |
YGL044C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO80 |
YGL150C |
Nucleosome spacing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAS17 |
YOR181W |
Actin assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YTH1 |
YPR107C |
Essential RNA-binding component of cleavage and polyadenylation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL4 |
YCR014C |
DNA polymerase IV |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL057W |
YDL057W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGT1 |
YDL200C |
DNA repair methyltransferase (6-O-methylguanine-DNA methylase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDL211C |
YDL211C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL12B |
YDR418W |
Ribosomal 60S subunit protein L12B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS60 |
YDR486C |
Protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIT1 |
YEL007W |
Transcriptional regulator of pseudohyphal growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MXR1 |
YER042W |
Methionine-S-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER076C |
YER076C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES5 |
YER092W |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT2 |
YER161C |
Protein involved in negative regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX18 |
YGR062C |
Protein required for membrane insertion of C-terminus of Cox2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDR11 |
YIL013C |
ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDS2 |
YJL146W |
Protein involved in modulation of Ime2p activity during meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCD2 |
YKL027W |
tRNA threonylcarbamoyladenosine dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTT109 |
YLL002W |
Histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES3 |
YLR052W |
Subunit of the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSO55 |
YLR281C |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUB1 |
YMR039C |
Transcriptional regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IBD2 |
YNL164C |
Component of the BUB2-dependent spindle checkpoint pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MCH4 |
YOL119C |
Protein with similarity to mammalian monocarboxylate permeases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTS1 |
YOR014W |
B-type regulatory subunit of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SNC2 |
YOR327C |
Vesicle membrane receptor protein (v-SNARE) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPL245W |
YPL245W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FEX2 |
YPL279C |
Protein involved in fluoride export |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR063C |
YPR063C |
ER-localized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RKM3 |
YBR030W |
Ribosomal lysine methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SFM1 |
YOR021C |
SPOUT methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STI1 |
YOR027W |
Evolutionarily-conserved Hsp90 cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL82 |
YNL314W |
Positive regulator of allophanate inducible genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TEN1 |
YLR010C |
Protein that regulates telomeric length |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARK1 |
YNL020C |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
