| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
genetic |
5 |
3 |
3 |
Dosage Rescue, Synthetic Growth Defect, Dosage Rescue, Synthetic Rescue, Synthetic Rescue |
| SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
physical |
4 |
4 |
3 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Two-hybrid |
| CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| STO1 |
YMR125W |
Large subunit of the nuclear mRNA cap-binding protein complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
| NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| ERV15 |
YBR210W |
Protein involved in export of proteins from the endoplasmic reticulum |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| HMI1 |
YOL095C |
Mitochondrial inner membrane localized ATP-dependent DNA helicase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
| SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
| COX5A |
YNL052W |
Subunit Va of cytochrome c oxidase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MRPL1 |
YDR116C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
| RAD18 |
YCR066W |
E3 ubiquitin ligase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
| YRA1 |
YDR381W |
Nuclear polyadenylated RNA-binding protein |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
| GEP7 |
YGL057C |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RPL8B |
YLL045C |
Ribosomal 60S subunit protein L8A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKY1 |
YMR216C |
SR protein kinase (SRPK) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MIC60 |
YKR016W |
Component of the MICOS complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| OYE2 |
YHR179W |
Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SLM3 |
YDL033C |
tRNA-specific 2-thiouridylase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| APS2 |
YJR058C |
Small subunit of the clathrin-associated adaptor complex AP-2 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
| COX12 |
YLR038C |
Subunit VIb of cytochrome c oxidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SUT1 |
YGL162W |
Zn(II)2Cys6 family transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| XDJ1 |
YLR090W |
Chaperone with a role in facilitating mitochondrial protein import |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ASH1 |
YKL185W |
Component of the Rpd3L histone deacetylase complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIM50 |
YPL063W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BFR2 |
YDR299W |
Component of the SSU and 90S preribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ERB1 |
YMR049C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POP4 |
YBR257W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HCA4 |
YJL033W |
DEAD box RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIR2 |
YDL175C |
RNA-binding subunit of the TRAMP nuclear RNA surveillance complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP3 |
YDR473C |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HPR1 |
YDR138W |
Subunit of THO/TREX complexes |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| THP2 |
YHR167W |
Subunit of the THO and TREX complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RBG2 |
YGR173W |
Protein with a role in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OLA1 |
YBR025C |
P-loop ATPase with similarity to human OLA1 and bacterial YchF |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HAP2 |
YGL237C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| ATP22 |
YDR350C |
Specific translational activator for the mitochondrial ATP6 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MDM10 |
YAL010C |
Subunit of both the ERMES and the SAM complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GEP3 |
YOR205C |
Protein required for mitochondrial ribosome small subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HDA2 |
YDR295C |
Subunit of HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| FAS2 |
YPL231W |
Alpha subunit of fatty acid synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PDB1 |
YBR221C |
E1 beta subunit of the pyruvate dehydrogenase (PDH) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL1 |
YNL102W |
Catalytic subunit of the DNA polymerase I alpha-primase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL6 |
YHR147C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC23 |
YPR181C |
GTPase-activating protein, stimulates the GTPase activity of Sar1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NEM1 |
YHR004C |
Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSH4 |
YFL003C |
Protein involved in meiotic recombination |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LAP2 |
YNL045W |
Leucyl aminopeptidase yscIV with epoxide hydrolase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC53 |
YDL132W |
Cullin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FDO1 |
YMR144W |
Protein involved in directionality of mating type switching |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GLC8 |
YMR311C |
Regulatory subunit of protein phosphatase 1 (Glc7p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HEF3 |
YNL014W |
Translational elongation factor EF-3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SOD2 |
YHR008C |
Mitochondrial manganese superoxide dismutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APT1 |
YML022W |
Adenine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF13 |
YMR094W |
Subunit of the CBF3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LSC1 |
YOR142W |
Alpha subunit of succinyl-CoA ligase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MAS2 |
YHR024C |
Alpha subunit of the mitochondrial processing protease (MPP) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIC19 |
YFR011C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ISA1 |
YLL027W |
Protein required for maturation of mitochondrial [4Fe-4S] proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR3 |
YMR052W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATG19 |
YOL082W |
Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL2 |
YDL127W |
Cyclin, interacts with cyclin-dependent kinase Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPO1 |
YNL012W |
Meiosis-specific prospore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SEC10 |
YLR166C |
Essential 100kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
physical |
1 |
1 |
1 |
Two-hybrid |
| SNO4 |
YMR322C |
Possible chaperone and cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFT1 |
YBL020W |
Membrane protein required for translocation of Man5GlcNac2-PP-Dol |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
physical |
1 |
1 |
1 |
Two-hybrid |
| DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PET111 |
YMR257C |
Mitochondrial translational activator specific for the COX2 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM19 |
YNR037C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPO20 |
YMR017W |
Meiosis-specific subunit of the t-SNARE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC19 |
YAL038W |
Pyruvate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MET31 |
YPL038W |
Zinc-finger DNA-binding transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OTU1 |
YFL044C |
Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TOF1 |
YNL273W |
Subunit of a replication-pausing checkpoint complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBN1 |
YCL052C |
Component of glycosylphosphatidylinositol-mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
| YUH1 |
YJR099W |
Ubiquitin C-terminal hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PLP1 |
YDR183W |
Protein that interacts with CCT (chaperonin containing TCP-1) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATX1 |
YNL259C |
Cytosolic copper metallochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMN1 |
YHR202W |
Putative AMP hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INP1 |
YMR204C |
Peripheral membrane protein of peroxisomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRN1 |
YGR093W |
Splicing factor that modulates turnover of branched RNAs by Dbr1p |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NFS1 |
YCL017C |
Cysteine desulfurase involved in iron-sulfur cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS23 |
YDR246W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRE3 |
YHR104W |
Aldose reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOB2 |
YPR117W |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC3 |
YHR087W |
Protein of unknown function involved in RNA metabolism |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YML131W |
YML131W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRPL22 |
YNL177C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERV2 |
YPR037C |
Flavin-linked sulfhydryl oxidase localized to the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MRPL32 |
YCR003W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| IMO32 |
YGR031W |
Conserved mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OGG1 |
YML060W |
Nuclear and mitochondrial glycosylase/lyase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDD3 |
YOL098C |
Putative metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPL35B |
YDL136W |
Ribosomal 60S subunit protein L35B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL36A |
YMR194W |
Ribosomal 60S subunit protein L36A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RDR1 |
YOR380W |
Transcriptional repressor involved in regulating multidrug resistance |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCT1 |
YBL011W |
Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTR1 |
YJR049C |
ATP-NADH kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DCR2 |
YLR361C |
Protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RIP1 |
YEL024W |
Ubiquinol-cytochrome-c reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPM2 |
YDL021W |
Nonfunctional homolog of Gpm1p phosphoglycerate mutase |
physical |
1 |
1 |
1 |
PCA |
| MAL13 |
YGR288W |
MAL-activator protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COS7 |
YDL248W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP17 |
YDR412W |
5' exoribonuclease required for 5' end processing of pre-60S rRNA |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| AMD2 |
YDR242W |
Putative amidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSN1 |
YOL116W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TEL2 |
YGR099W |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TCA17 |
YEL048C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YNR064C |
YNR064C |
Epoxide hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EDC1 |
YGL222C |
RNA-binding protein that activates mRNA decapping directly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGA2 |
YGL032C |
Adhesion subunit of a-agglutinin of a-cells |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHA2 |
YNL316C |
Prephenate dehydratase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| JAC1 |
YGL018C |
Specialized J-protein that functions in Fe-S cluster biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CMI7 |
YIL002W-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ECM4 |
YKR076W |
S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CPR8 |
YNR028W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR140W |
YHR140W |
Endoplasmic reticulum protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NGL1 |
YOL042W |
Putative endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF2 |
YNR018W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SDH5 |
YOL071W |
Protein required for flavinylation of Sdh1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BNA4 |
YBL098W |
Kynurenine 3-monooxygenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MME1 |
YMR166C |
Transporter of the mitochondrial inner membrane that exports magnesium |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRF1 |
YHR038W |
Mitochondrial ribosome recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCF3 |
YBR255C-A |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| THR4 |
YCR053W |
Threonine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPR172W |
YPR172W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IMA4 |
YJL221C |
Alpha-glucosidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PES4 |
YFR023W |
Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YME1 |
YPR024W |
Catalytic subunit of i-AAA protease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC59 |
YMR013C |
Dolichol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC5 |
YOR118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PEX9 |
YMR018W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YIL152W |
YIL152W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR053C |
YLR053C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YLR152C |
YLR152C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL242C |
YGL242C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YCL001W-B |
YCL001W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHH3 |
YMR118C |
Putative mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL036W |
YGL036W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR278C |
YLR278C |
Zinc-cluster protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YMR272W-B |
YMR272W-B |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YNL194C |
YNL194C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YOL159C-A |
YOL159C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YPR108W-A |
YPR108W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TSR4 |
YOL022C |
Cytoplasmic assembly chaperone for ribosomal protein Rps2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YDR034W-B |
YDR034W-B |
Predicted tail-anchored plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YER134C |
YER134C |
Magnesium-dependent acid phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YPS5 |
YGL259W |
Protein with similarity to GPI-anchored aspartic proteases |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGL262W |
YGL262W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YGR035W-A |
YGR035W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YHR050W-A |
YHR050W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YJL118W |
YJL118W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR154C-G |
YLR154C-G |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR179C |
YLR179C |
Protein of unknown function with similarity to Tfs1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR464W |
YLR464W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR030W-A |
YMR030W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR084W |
YMR084W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YMR310C |
YMR310C |
Putative methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
