Standard name Systematic name Name description Description
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) Subunit of the prohibitin complex (Phb1p-Phb2p); prohibitin is a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation; prohibitin deficiency induces a mitochondrial unfolded protein response (mtUPR)
Visualize the interactome of PHB2
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Mito 0.969 0.653 0.565
Nucleolus 0.115 0.061 NaN
Vac/Vac Memb 0.094 0.238 0.141
Nucleus NaN 0.068 0.076
Cell Periphery NaN NaN 0.054
Endosome NaN NaN 0.076
Golgi NaN NaN 0.120
SpindlePole NaN NaN 0.109

GFP localization & abundance

GFP localization GFP abundance
mitochondrion 2850

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PHB2 1 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PSD1 YNL169C Phosphatidylserine decarboxylase of the mitochondrial inner membrane genetic 6 3 6 Synthetic Lethality, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 5 4 5 Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect, Positive Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 4 3 4 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 4 3 4 Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 4 3 4 Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Co-fractionation
PUF3 YLL013C Protein of the mitochondrial outer surface physical 4 1 4 Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA, Affinity Capture-RNA
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 4 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic
INA17 YPL099C F1F0 ATPase synthase peripheral stalk assembly factor genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 3 2 3 Synthetic Rescue, Negative Genetic, Negative Genetic
KIN4 YOR233W Serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 3 2 2 Positive Genetic, Negative Genetic, Positive Genetic
ATP10 YLR393W Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UBP3 YER151C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
UPS2 YLR168C Mitochondrial intermembrane space protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CRD1 YDL142C Cardiolipin synthase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ARD1 YHR013C Subunit of protein N-terminal acetyltransferase NatA genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
DOA4 YDR069C Ubiquitin hydrolase genetic 2 2 2 Negative Genetic, Positive Genetic
PET9 YBL030C Major ADP/ATP carrier of the mitochondrial inner membrane genetic 2 2 2 Synthetic Lethality, Positive Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
SPE1 YKL184W Ornithine decarboxylase genetic 2 2 2 Negative Genetic, Positive Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 2 2 2 Synthetic Lethality, Negative Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
AIM25 YJR100C Mitochondria protein of unknown function genetic 2 1 2 Positive Genetic, Positive Genetic
ECM2 YBR065C Pre-mRNA splicing factor genetic 2 1 2 Negative Genetic, Negative Genetic
BDF1 YLR399C BET family transcriptional regulator genetic 2 1 2 Negative Genetic, Negative Genetic
IWR1 YDL115C RNA polymerase II transport factor, conserved from yeast to humans genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
DNM1 YLL001W Dynamin-related GTPase involved in mitochondrial organization genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
APP1 YNL094W Phosphatidate phosphatase, converts phosphatidate to diacylglycerol genetic 2 1 2 Negative Genetic, Negative Genetic
MGE1 YOR232W Mitochondrial matrix cochaperone genetic 2 1 2 Negative Genetic, Negative Genetic
OYE3 YPL171C Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 2 1 2 Negative Genetic, Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 2 1 2 Negative Genetic, Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 2 1 2 Negative Genetic, Negative Genetic
AFG3 YER017C Mitochondrial inner membrane m-AAA protease component genetic 2 1 2 Negative Genetic, Negative Genetic
FMP16 YDR070C Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance genetic 2 1 2 Negative Genetic, Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 2 1 2 Negative Genetic, Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 2 1 2 Negative Genetic, Negative Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 2 1 2 Negative Genetic, Negative Genetic
FUS2 YMR232W Cell fusion regulator genetic 2 1 2 Negative Genetic, Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 2 1 2 Negative Genetic, Negative Genetic
MDL1 YLR188W Mitochondrial inner membrane half-type ABC transporter genetic 2 1 2 Negative Genetic, Negative Genetic
ILV6 YCL009C Regulatory subunit of acetolactate synthase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP18 YML081C-A Subunit of the mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
ATP14 YLR295C Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase genetic 2 1 2 Negative Genetic, Negative Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component genetic 2 1 2 Negative Genetic, Negative Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
PRX1 YBL064C Mitochondrial peroxiredoxin with thioredoxin peroxidase activity genetic 2 1 2 Negative Genetic, Negative Genetic
TAF5 YBR198C Subunit (90 kDa) of TFIID and SAGA complexes genetic 2 1 2 Negative Genetic, Negative Genetic
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 2 1 2 Negative Genetic, Negative Genetic
TIM22 YDL217C Essential core component of mitochondrial TIM22 complex genetic 2 1 2 Negative Genetic, Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 2 1 2 Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 2 1 2 Negative Genetic, Negative Genetic
UBC6 YER100W Ubiquitin-conjugating enzyme involved in ERAD genetic 2 1 2 Negative Genetic, Negative Genetic
SVP26 YHR181W ER exit adaptor for Golgi mannosyltransferases genetic 2 1 2 Negative Genetic, Negative Genetic
TPM2 YIL138C Minor isoform of tropomyosin genetic 2 1 2 Negative Genetic, Negative Genetic
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 2 1 2 Negative Genetic, Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 2 1 2 Negative Genetic, Negative Genetic
YET2 YMR040W Protein of unknown function that may interact with ribosomes genetic 2 1 2 Negative Genetic, Negative Genetic
PYP1 YNL010W Sugar alcohol phosphatase genetic 2 1 2 Negative Genetic, Negative Genetic
SLY41 YOR307C Protein involved in ER-to-Golgi transport genetic 2 1 2 Negative Genetic, Negative Genetic
YPL264C YPL264C Endoplasmic reticulum protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TIM18 YOR297C Component of the mitochondrial TIM22 complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS11B YBR048W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Positive Genetic, Positive Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 2 1 2 Positive Genetic, Positive Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 2 1 2 Negative Genetic, Negative Genetic
YML108W YML108W Protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 2 1 2 Positive Genetic, Positive Genetic
DEG1 YFL001W tRNA:pseudouridine synthase genetic 2 1 2 Negative Genetic, Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 2 1 2 Negative Genetic, Negative Genetic
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 2 1 2 Negative Genetic, Negative Genetic
EMI1 YDR512C Non-essential protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
FMP30 YPL103C Protein with a role in maintaining mitochondrial morphology genetic 2 1 2 Negative Genetic, Negative Genetic
PDE2 YOR360C High-affinity cyclic AMP phosphodiesterase genetic 2 1 2 Negative Genetic, Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 2 1 1 Negative Genetic, Negative Genetic
PAM17 YKR065C Constituent of the TIM23 complex genetic 2 1 1 Negative Genetic, Negative Genetic
GEP7 YGL057C Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
YDL157C YDL157C Putative protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
MTC3 YGL226W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CDC73 YLR418C Component of the Paf1p complex genetic 1 1 1 Negative Genetic
DSN1 YIR010W Essential component of the outer kinetochore MIND complex genetic 1 1 1 Negative Genetic
NSL1 YPL233W Essential component of the MIND kinetochore complex genetic 1 1 1 Negative Genetic
NSE1 YLR007W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NOP9 YJL010C Essential subunit of U3-containing 90S preribosome genetic 1 1 1 Negative Genetic
HOL1 YNR055C Putative transporter in the major facilitator superfamily genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
CDC42 YLR229C Small rho-like GTPase genetic 1 1 1 Positive Genetic
GAR1 YHR089C Protein component of the H/ACA snoRNP pseudouridylase complex genetic 1 1 1 Negative Genetic
HCA4 YJL033W DEAD box RNA helicase genetic 1 1 1 Negative Genetic
LSM1 YJL124C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CDC48 YDL126C AAA ATPase with protein-unfoldase activity genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
ERG26 YGL001C C-3 sterol dehydrogenase genetic 1 1 1 Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 1 1 1 Positive Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 1 1 1 Negative Genetic
COX6 YHR051W Subunit VI of cytochrome c oxidase (Complex IV) genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CUS1 YMR240C Protein required for assembly of U2 snRNP into the spliceosome genetic 1 1 1 Negative Genetic
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
ECM1 YAL059W Pre-ribosomal factor involved in 60S ribosomal protein subunit export genetic 1 1 1 Positive Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
ERP2 YAL007C Member of the p24 family involved in ER to Golgi transport physical 1 1 1 Affinity Capture-MS
FRS1 YLR060W Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
AEP1 YMR064W Protein required for expression of the mitochondrial OLI1 gene genetic 1 1 1 Negative Genetic
HTB2 YBL002W Histone H2B genetic 1 1 1 Negative Genetic
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Positive Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
KRS1 YDR037W Lysyl-tRNA synthetase genetic 1 1 1 Negative Genetic
GEA2 YEL022W Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) physical 1 1 1 Affinity Capture-MS
LCB1 YMR296C Component of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
MED11 YMR112C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
MRPL1 YDR116C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MRP20 YDR405W Mitochondrial ribosomal protein of the large subunit physical 1 1 1 Proximity Label-MS
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
HDA3 YPR179C Subunit of HDA1 histone deacetylase complex genetic 1 1 1 Positive Genetic
MGM101 YJR144W Protein with a role in mitochondrial DNA recombinational repair genetic 1 1 1 Negative Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
KCC4 YCL024W Protein kinase of the bud neck involved in the septin checkpoint physical 1 1 1 Biochemical Activity
ARP8 YOR141C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ITC1 YGL133W Subunit of ATP-dependent Isw2p-Itc1p chromatin remodeling complex genetic 1 1 1 Positive Genetic
NHP10 YDL002C Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
NPL4 YBR170C Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Positive Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
MIR1 YJR077C Mitochondrial phosphate carrier genetic 1 1 1 Positive Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
NAT1 YDL040C Subunit of protein N-terminal acetyltransferase NatA genetic 1 1 1 Synthetic Growth Defect
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Negative Genetic
CCT7 YJL111W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
CAB5 YDR196C Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) genetic 1 1 1 Negative Genetic
ATP2 YJR121W Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
AIM41 YOR215C Protein of unknown function genetic 1 1 1 Negative Genetic
ATP4 YPL078C Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) genetic 1 1 1 Positive Genetic
CRZ1 YNL027W Transcription factor, activates transcription of stress response genes genetic 1 1 1 Negative Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Positive Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
AAC3 YBR085W Mitochondrial inner membrane ADP/ATP translocator genetic 1 1 1 Positive Genetic
CMP2 YML057W Calcineurin A genetic 1 1 1 Positive Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
HXT6 YDR343C High-affinity glucose transporter genetic 1 1 1 Negative Genetic
ESL2 YKR096W hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
PDI1 YCL043C Protein disulfide isomerase genetic 1 1 1 Negative Genetic
KDX1 YKL161C Protein kinase genetic 1 1 1 Negative Genetic
AYR1 YIL124W Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase genetic 1 1 1 Negative Genetic
DYN2 YDR424C Cytoplasmic light chain dynein, microtubule motor protein genetic 1 1 1 Negative Genetic
MLH3 YPL164C Protein involved in DNA mismatch repair and meiotic recombination genetic 1 1 1 Negative Genetic
CCT3 YJL014W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
KAP122 YGL016W Karyopherin beta physical 1 1 1 Affinity Capture-MS
GDB1 YPR184W Glycogen debranching enzyme genetic 1 1 1 Negative Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Negative Genetic
HRT3 YLR097C Putative SCF-ubiquitin ligase F-box protein genetic 1 1 1 Negative Genetic
LRO1 YNR008W Acyltransferase that converts diacylglycerol to triacylglycerol (TGA) genetic 1 1 1 Negative Genetic
FRS2 YFL022C Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
DNL4 YOR005C DNA ligase required for nonhomologous end-joining (NHEJ) genetic 1 1 1 Negative Genetic
CDC15 YAR019C Hippo-like kinase of the Mitotic Exit Network genetic 1 1 1 Positive Genetic
MKK2 YPL140C MAPKK involved in the protein kinase C signaling pathway genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Negative Genetic
MNN9 YPL050C Subunit of Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
HAP3 YBL021C Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Negative Genetic
ELC1 YPL046C Elongin C, conserved among eukaryotes genetic 1 1 1 Negative Genetic
ELG1 YOR144C Subunit of an alternative replication factor C complex genetic 1 1 1 Negative Genetic
ASR1 YPR093C Ubiquitin ligase that modifies and regulates RNA Pol II genetic 1 1 1 Negative Genetic
CPR3 YML078W Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 1 1 1 Positive Genetic
DEF1 YKL054C RNAPII degradation factor genetic 1 1 1 Positive Genetic
MSG5 YNL053W Dual-specificity protein phosphatase genetic 1 1 1 Positive Genetic
FUS3 YBL016W Mitogen-activated serine/threonine protein kinase involved in mating genetic 1 1 1 Positive Genetic
MIC19 YFR011C Component of the MICOS complex genetic 1 1 1 Negative Genetic
NUP53 YMR153W FG-nucleoporin component of central core of nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
GBP2 YCL011C Poly(A+) RNA-binding protein genetic 1 1 1 Negative Genetic
ADE6 YGR061C Formylglycinamidine-ribonucleotide (FGAM)-synthetase genetic 1 1 1 Negative Genetic
APE2 YKL157W Aminopeptidase yscII genetic 1 1 1 Negative Genetic
NTA1 YJR062C Amidase genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Positive Genetic
JJJ1 YNL227C Co-chaperone that stimulates the ATPase activity of Ssa1p genetic 1 1 1 Positive Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
DAL82 YNL314W Positive regulator of allophanate inducible genes genetic 1 1 1 Negative Genetic
INO2 YDR123C Transcription factor genetic 1 1 1 Negative Genetic
LEU4 YNL104C Alpha-isopropylmalate synthase (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
PCL8 YPL219W Cyclin genetic 1 1 1 Negative Genetic
MCO14 YHL018W Putative 4a-hydroxytetrahydrobiopterin dehydratase genetic 1 1 1 Negative Genetic
PFS1 YHR185C Sporulation protein required for prospore membrane formation genetic 1 1 1 Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex physical 1 1 1 Affinity Capture-MS
BMT2 YBR141C Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
ART5 YGR068C Protein proposed to regulate endocytosis of plasma membrane proteins genetic 1 1 1 Negative Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 1 1 1 Negative Genetic
ESL1 YIL151C hEST1A/B (SMG5/6)-like protein genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Synthetic Growth Defect
DOC1 YGL240W Processivity factor genetic 1 1 1 Positive Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
IES4 YOR189W Component of the INO80 chromatiin remodeling complex genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
DBP5 YOR046C Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Synthetic Growth Defect
DCD1 YHR144C Deoxycytidine monophosphate (dCMP) deaminase genetic 1 1 1 Negative Genetic
ELO3 YLR372W Elongase genetic 1 1 1 Positive Genetic
GIM4 YEL003W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
ORC3 YLL004W Subunit of the origin recognition complex (ORC) genetic 1 1 1 Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 1 1 1 Positive Genetic
FIG4 YNL325C Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase genetic 1 1 1 Negative Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Negative Genetic
GAL4 YPL248C DNA-binding transcription factor required for activating GAL genes genetic 1 1 1 Negative Genetic
EMP46 YLR080W Integral membrane component of ER-derived COPII-coated vesicles genetic 1 1 1 Negative Genetic
GAP1 YKR039W General amino acid permease genetic 1 1 1 Positive Genetic
ESC2 YDR363W Sumo-like domain protein genetic 1 1 1 Positive Genetic
CAD1 YDR423C AP-1-like basic leucine zipper (bZIP) transcriptional activator genetic 1 1 1 Negative Genetic
GSY2 YLR258W Glycogen synthase genetic 1 1 1 Negative Genetic
HCH1 YNL281W Heat shock protein regulator genetic 1 1 1 Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
HFA1 YMR207C Mitochondrial acetyl-coenzyme A carboxylase genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
DJP1 YIR004W ER-associated chaperone involved in protein targeting genetic 1 1 1 Negative Genetic
NNK1 YKL171W Protein kinase physical 1 1 1 Biochemical Activity
BAT2 YJR148W Cytosolic branched-chain amino acid (BCAA) aminotransferase genetic 1 1 1 Negative Genetic
BUD17 YNR027W Putative pyridoxal kinase genetic 1 1 1 Negative Genetic
LRS4 YDR439W Nucleolar protein that forms a complex with Csm1p genetic 1 1 1 Negative Genetic
CQD1 YPL109C UbiB family mitochondrial protein genetic 1 1 1 Negative Genetic
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
AUR1 YKL004W Phosphatidylinositol:ceramide phosphoinositol transferase genetic 1 1 1 Negative Genetic
PAM16 YJL104W Subunit of the import motor (PAM complex) genetic 1 1 1 Synthetic Growth Defect
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex physical 1 1 1 Affinity Capture-MS
OXA1 YER154W Mitochondrial inner membrane insertase physical 1 1 1 Proximity Label-MS
OXA1 YER154W Mitochondrial inner membrane insertase genetic 1 1 1 Negative Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Affinity Capture-RNA
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
PHB1 YGR132C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Positive Genetic
ENT1 YDL161W Epsin-like protein involved in endocytosis and actin patch assembly genetic 1 1 1 Negative Genetic
DYS1 YHR068W Deoxyhypusine synthase genetic 1 1 1 Negative Genetic
ATM1 YMR301C Mitochondrial inner membrane ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
CNN1 YFR046C Kinetochore protein genetic 1 1 1 Negative Genetic
GLR1 YPL091W Cytosolic and mitochondrial glutathione oxidoreductase genetic 1 1 1 Positive Genetic
ASF2 YDL197C Anti-silencing protein genetic 1 1 1 Negative Genetic
GEF1 YJR040W Voltage-gated chloride channel genetic 1 1 1 Positive Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 1 1 1 Positive Genetic
ALG1 YBR110W Mannosyltransferase genetic 1 1 1 Negative Genetic
ASG7 YJL170C Protein that regulates signaling from G protein beta subunit Ste4p genetic 1 1 1 Negative Genetic
JHD2 YJR119C JmjC domain family histone demethylase genetic 1 1 1 Negative Genetic
DDR2 YOL052C-A Multi-stress response protein genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Positive Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Negative Genetic
DIC1 YLR348C Mitochondrial dicarboxylate carrier genetic 1 1 1 Negative Genetic
BTT1 YDR252W Heterotrimeric nascent polypeptide-associated complex beta3 subunit genetic 1 1 1 Positive Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Negative Genetic
ADE16 YLR028C Enzyme of 'de novo' purine biosynthesis genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
CRS1 YNL247W Cysteinyl-tRNA synthetase genetic 1 1 1 Negative Genetic
MVB12 YGR206W ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers genetic 1 1 1 Negative Genetic
INA22 YIR024C F1F0 ATP synthase peripheral stalk assembly factor genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Positive Genetic
ELF1 YKL160W Transcription elongation factor with a conserved zinc finger domain genetic 1 1 1 Negative Genetic
NAM2 YLR382C Mitochondrial leucyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CSS1 YIL169C Protein of unknown function, secreted when constitutively expressed genetic 1 1 1 Negative Genetic
IRC25 YLR021W Component of a heterodimeric Poc4p-Irc25p chaperone genetic 1 1 1 Positive Genetic
JID1 YPR061C Probable Hsp40p co-chaperone genetic 1 1 1 Negative Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase physical 1 1 1 Affinity Capture-MS
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 1 1 1 Positive Genetic
YTA12 YMR089C Mitochondrial inner membrane m-AAA protease component physical 1 1 1 Affinity Capture-MS
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
PIM1 YBL022C ATP-dependent Lon protease physical 1 1 1 Affinity Capture-Western
PIM1 YBL022C ATP-dependent Lon protease genetic 1 1 1 Synthetic Growth Defect
SIP2 YGL208W One of three alternate beta subunits of the Snf1 kinase complex physical 1 1 1 Affinity Capture-MS
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) physical 1 1 1 Affinity Capture-MS
RMP1 YLR145W Subunit of RNase MRP physical 1 1 1 Affinity Capture-RNA
PUF3 YLL013C Protein of the mitochondrial outer surface genetic 1 1 1 Positive Genetic
SSC1 YJR045C Hsp70 family ATPase physical 1 1 1 Affinity Capture-MS
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
TMA108 YIL137C Ribosome-associated, nascent chain binding factor physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
PTC5 YOR090C Mitochondrial type 2C protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
PTC7 YHR076W Type 2C serine/threonine protein phosphatase (PP2C) physical 1 1 1 Affinity Capture-MS
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
TOM22 YNL131W Component of the TOM (Translocase of Outer Membrane) complex physical 1 1 1 Affinity Capture-MS
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex physical 1 1 1 Affinity Capture-MS
SAS3 YBL052C Histone acetyltransferase catalytic subunit of NuA3 complex genetic 1 1 1 Negative Genetic
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
TFC1 YBR123C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
YBR238C YBR238C Mitochondrial membrane protein genetic 1 1 1 Negative Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Negative Genetic
UBP1 YDL122W Ubiquitin-specific protease genetic 1 1 1 Negative Genetic
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Positive Genetic
SWM1 YDR260C Subunit of the anaphase-promoting complex (APC) genetic 1 1 1 Negative Genetic
RMT2 YDR465C Arginine N5 methyltransferase genetic 1 1 1 Negative Genetic
PXP1 YEL020C Peroxisomal matrix protein genetic 1 1 1 Negative Genetic
SMC1 YFL008W Subunit of the multiprotein cohesin complex genetic 1 1 1 Negative Genetic
STR3 YGL184C Peroxisomal cystathionine beta-lyase genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 1 1 1 Negative Genetic
YJR120W YJR120W Protein of unknown function genetic 1 1 1 Negative Genetic
SRY1 YKL218C 3-hydroxyaspartate dehydratase genetic 1 1 1 Negative Genetic
YRA2 YKL214C Member of the REF (RNA and export factor binding proteins) family genetic 1 1 1 Negative Genetic
PIR1 YKL164C O-glycosylated protein required for cell wall stability genetic 1 1 1 Negative Genetic
SNZ1 YMR096W Subunit of a two-component pyridoxal-5'-phosphate synthase genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
SNO4 YMR322C Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Positive Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Positive Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
RSC6 YCR052W Component of the RSC chromatin remodeling complex genetic 1 1 1 Positive Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
SMD2 YLR275W Core Sm protein Sm D2 genetic 1 1 1 Positive Genetic
UTP14 YML093W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Positive Genetic
SOM1 YEL059C-A Subunit of the mitochondrial inner membrane peptidase (IMP) genetic 1 1 1 Positive Genetic
TDA8 YAL064C-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
RGT1 YKL038W Glucose-responsive transcription factor genetic 1 1 1 Positive Genetic
RPS21A YKR057W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
RPS7B YNL096C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SYH1 YPL105C Protein of unknown function that influences nuclear pore distribution genetic 1 1 1 Positive Genetic
YPL150W YPL150W Protein kinase of unknown cellular role genetic 1 1 1 Positive Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Positive Genetic
RSO55 YLR281C Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
RRG9 YNL213C Protein of unknown function genetic 1 1 1 Positive Genetic
PRP45 YAL032C Protein required for pre-mRNA splicing genetic 1 1 1 Negative Genetic
TSC3 YBR058C-A Protein that stimulates the activity of serine palmitoyltransferase genetic 1 1 1 Negative Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
SRB6 YBR253W Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Negative Genetic
SEC31 YDL195W Component of the Sec13p-Sec31p complex of the COPII vesicle coat genetic 1 1 1 Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
SPC25 YER018C Component of the kinetochore-associated Ndc80 complex genetic 1 1 1 Negative Genetic
SEC15 YGL233W Essential 113 kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
UTP18 YJL069C Small-subunit processome protein involved in pre-18S rRNA maturation genetic 1 1 1 Negative Genetic
URA6 YKL024C Uridylate kinase genetic 1 1 1 Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 1 1 1 Negative Genetic
STU2 YLR045C Microtubule polymerase of the XMAP215/Dis1 family genetic 1 1 1 Negative Genetic
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
TEM1 YML064C GTPase involved in initiation of Mitotic Exit Network (MEN) genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Negative Genetic
SEC2 YNL272C Guanyl-nucleotide exchange factor for the small G-protein Sec4p genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
RFC1 YOR217W Subunit of heteropentameric Replication factor C (RF-C) genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
RVB2 YPL235W ATP-dependent DNA helicase, also known as reptin genetic 1 1 1 Negative Genetic
RDS3 YPR094W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
YAR068W YAR068W Fungal-specific protein of unknown function genetic 1 1 1 Negative Genetic
YBR200W-A YBR200W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLC1 YDL052C 1-acyl-sn-glycerol-3-phosphate acyltransferase genetic 1 1 1 Negative Genetic
PPH3 YDR075W Catalytic subunit of protein phosphatase PP4 complex genetic 1 1 1 Negative Genetic
TMA64 YDR117C Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes genetic 1 1 1 Negative Genetic
TSA2 YDR453C Stress inducible cytoplasmic thioredoxin peroxidase genetic 1 1 1 Negative Genetic
SDD1 YEL057C Protein of unknown function genetic 1 1 1 Negative Genetic
YER039C-A YER039C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
PRS2 YER099C 5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase genetic 1 1 1 Negative Genetic
YFL012W YFL012W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
SCT1 YBL011W Glycerol 3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase genetic 1 1 1 Negative Genetic
SEF1 YBL066C Putative transcription factor genetic 1 1 1 Negative Genetic
YSA1 YBR111C Nudix hydrolase family member with ADP-ribose pyrophosphatase activity genetic 1 1 1 Negative Genetic
YDL012C YDL012C Tail-anchored plasma membrane protein with a conserved CYSTM module genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
PTC2 YER089C Type 2C protein phosphatase (PP2C) genetic 1 1 1 Negative Genetic
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Negative Genetic
YJR084W YJR084W Protein that forms a complex with Thp3p genetic 1 1 1 Negative Genetic
YET1 YKL065C Endoplasmic reticulum transmembrane protein genetic 1 1 1 Negative Genetic
PSR1 YLL010C Plasma membrane-associated protein phosphatase genetic 1 1 1 Negative Genetic
PUS5 YLR165C Pseudouridine synthase genetic 1 1 1 Negative Genetic
YOL153C YOL153C Blocked reading frame, contains two in-frame stops in translation genetic 1 1 1 Negative Genetic
VHS3 YOR054C Negative regulatory subunit of protein phosphatase 1 Ppz1p genetic 1 1 1 Negative Genetic
RIM20 YOR275C Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
TRM44 YPL030W tRNA(Ser) Um(44) 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
YHR045W YHR045W Putative protein of unknown function genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
XBP1 YIL101C Transcriptional repressor genetic 1 1 1 Negative Genetic
YIR021W-A YIR021W-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YJL107C YJL107C Putative protein of unknown function genetic 1 1 1 Negative Genetic
RAD26 YJR035W Protein involved in transcription-coupled nucleotide excision repair genetic 1 1 1 Negative Genetic
YJR098C YJR098C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SOR1 YJR159W Sorbitol dehydrogenase genetic 1 1 1 Negative Genetic
YKL063C YKL063C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SEG2 YKL105C Eisosome component genetic 1 1 1 Negative Genetic
YKR011C YKR011C Protein of unknown function genetic 1 1 1 Negative Genetic
PSR2 YLR019W Putative plasma membrane phosphatase genetic 1 1 1 Negative Genetic
YLR419W YLR419W Putative helicase with limited sequence similarity to human Rb protein genetic 1 1 1 Negative Genetic
RCF1 YML030W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
YML053C YML053C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YML054C-A YML054C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
STB4 YMR019W Putative transcription factor genetic 1 1 1 Negative Genetic
PSO2 YMR137C Nuclease required for DNA single- and double-strand break repair genetic 1 1 1 Negative Genetic
YMR226C YMR226C NADP(+)-dependent serine dehydrogenase and carbonyl reductase genetic 1 1 1 Negative Genetic
TPS3 YMR261C Regulatory subunit of trehalose-6-phosphate synthase/phosphatase genetic 1 1 1 Negative Genetic
TPM1 YNL079C Major isoform of tropomyosin genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
YNL134C YNL134C NADH-dependent aldehyde reductase genetic 1 1 1 Negative Genetic
TOS6 YNL300W Glycosylphosphatidylinositol-dependent cell wall protein genetic 1 1 1 Negative Genetic
TRM13 YOL125W 2'-O-methyltransferase genetic 1 1 1 Negative Genetic
TOM6 YOR045W Component of the TOM (translocase of outer membrane) complex genetic 1 1 1 Negative Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
SPE2 YOL052C S-adenosylmethionine decarboxylase genetic 1 1 1 Positive Genetic
PUT2 YHR037W Delta-1-pyrroline-5-carboxylate dehydrogenase genetic 1 1 1 Positive Genetic
URA5 YML106W Major orotate phosphoribosyltransferase (OPRTase) isozyme genetic 1 1 1 Positive Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Positive Genetic
RPS19A YOL121C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SAK1 YER129W Upstream serine/threonine kinase for the SNF1 complex genetic 1 1 1 Negative Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Positive Genetic
SSM4 YIL030C Membrane-embedded ubiquitin-protein ligase and retrotranslocase genetic 1 1 1 Negative Genetic
RPL11B YGR085C Ribosomal 60S subunit protein L11B genetic 1 1 1 Positive Genetic
YBT1 YLL048C Transporter of the ATP-binding cassette (ABC) family genetic 1 1 1 Positive Genetic
RRD1 YIL153W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Positive Genetic
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Positive Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
RPS10B YMR230W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
YAT1 YAR035W Outer mitochondrial carnitine acetyltransferase genetic 1 1 1 Positive Genetic
SNF5 YBR289W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YUH1 YJR099W Ubiquitin C-terminal hydrolase genetic 1 1 1 Positive Genetic
TOP1 YOL006C Topoisomerase I genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SIW14 YNL032W Inositol phosphatase involved in inositol pyrophosphate metabolism genetic 1 1 1 Positive Genetic
QCR2 YPR191W Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Positive Genetic
SNF1 YDR477W AMP-activated S/T protein kinase genetic 1 1 1 Negative Genetic
RPS10A YOR293W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
RPS19B YNL302C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting genetic 1 1 1 Positive Genetic
UME1 YPL139C Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Positive Genetic
PRE7 YBL041W Beta 6 subunit of the 20S proteasome genetic 1 1 1 Positive Genetic
SKI8 YGL213C Ski complex component and WD-repeat protein genetic 1 1 1 Positive Genetic
PML39 YML107C Protein required for nuclear retention of unspliced pre-mRNAs genetic 1 1 1 Positive Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Negative Genetic
REC8 YPR007C Meiosis-specific component of the sister chromatid cohesion complex genetic 1 1 1 Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 1 1 1 Negative Genetic
TDA1 YMR291W Protein kinase of unknown cellular role genetic 1 1 1 Negative Genetic
SER1 YOR184W 3-phosphoserine aminotransferase genetic 1 1 1 Negative Genetic
SCD6 YPR129W Repressor of translation initiation genetic 1 1 1 Negative Genetic
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 1 1 1 Positive Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 1 1 1 Negative Genetic
CMK2 YOL016C Calmodulin-dependent protein kinase genetic 1 1 1 Negative Genetic
ADD37 YMR184W Protein of unknown function genetic 1 1 1 Negative Genetic
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Positive Genetic
AIM11 YER093C-A Protein of unknown function genetic 1 1 1 Negative Genetic
ENT4 YLL038C Protein of unknown function genetic 1 1 1 Negative Genetic
MGR3 YMR115W Subunit of the mitochondrial (mt) i-AAA protease supercomplex genetic 1 1 1 Negative Genetic
PAU22 YPL282C Protein of unknown function genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
AAD4 YDL243C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Positive Genetic
MDM38 YOL027C Membrane-associated mitochondrial ribosome receptor genetic 1 1 1 Positive Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 1 1 1 Positive Genetic
GIS1 YDR096W Histone demethylase and transcription factor physical 1 1 1 Affinity Capture-MS
OM14 YBR230C Mitochondrial outer membrane receptor for cytosolic ribosomes physical 1 1 1 Affinity Capture-MS
ERV1 YGR029W Flavin-linked sulfhydryl oxidase of the mitochondrial IMS genetic 1 1 1 Negative Genetic
ASI1 YMR119W Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Positive Genetic
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
HVG1 YER039C Protein of unknown function genetic 1 1 1 Negative Genetic
AAD14 YNL331C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
NOP10 YHR072W-A Subunit of box H/ACA snoRNP complex genetic 1 1 1 Negative Genetic
ALG14 YBR070C Component of UDP-GlcNAc transferase genetic 1 1 1 Positive Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
ADK2 YER170W Mitochondrial adenylate kinase genetic 1 1 1 Negative Genetic
MLO127 YJR039W Mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
ALG9 YNL219C Mannosyltransferase, involved in N-linked glycosylation genetic 1 1 1 Positive Genetic
FIT2 YOR382W Mannoprotein that is incorporated into the cell wall genetic 1 1 1 Negative Genetic
GCG1 YER163C Gamma-glutamyl cyclotransferase genetic 1 1 1 Negative Genetic
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
MIC60 YKR016W Component of the MICOS complex genetic 1 1 1 Negative Genetic
APA2 YDR530C Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase II genetic 1 1 1 Negative Genetic
ERG9 YHR190W Farnesyl-diphosphate farnesyl transferase (squalene synthase) genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
MIC12 YBR262C Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
DPC25 YPL107W Putative mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic
CYT2 YKL087C Cytochrome c1 heme lyase genetic 1 1 1 Negative Genetic
MCH4 YOL119C Protein with similarity to mammalian monocarboxylate permeases genetic 1 1 1 Negative Genetic
EFM4 YIL064W Lysine methyltransferase genetic 1 1 1 Negative Genetic
MCT1 YOR221C Predicted malonyl-CoA:ACP transferase genetic 1 1 1 Negative Genetic
MIC10 YCL057C-A Conserved component of the MICOS complex physical 1 1 1 Affinity Capture-MS
ICY1 YMR195W Protein of unknown function genetic 1 1 1 Negative Genetic
ALD3 YMR169C Cytoplasmic aldehyde dehydrogenase genetic 1 1 1 Positive Genetic
CUP1-2 YHR055C Metallothionein genetic 1 1 1 Negative Genetic
DFR1 YOR236W Dihydrofolate reductase involved in tetrahydrofolate biosynthesis genetic 1 1 1 Positive Genetic
GAS2 YLR343W 1,3-beta-glucanosyltransferase genetic 1 1 1 Negative Genetic
ITR2 YOL103W Myo-inositol transporter genetic 1 1 1 Negative Genetic
GCV1 YDR019C T subunit of the mitochondrial glycine decarboxylase complex genetic 1 1 1 Negative Genetic
AIM33 YML087C Protein of unknown function, highly conserved across species genetic 1 1 1 Positive Genetic
NGL1 YOL042W Putative endonuclease genetic 1 1 1 Negative Genetic
BNA4 YBL098W Kynurenine 3-monooxygenase genetic 1 1 1 Positive Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Positive Genetic
OCT1 YKL134C Mitochondrial intermediate peptidase genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane physical 1 1 1 Affinity Capture-MS
IRC21 YMR073C Protein of unknown function genetic 1 1 1 Positive Genetic
PET20 YPL159C Mitochondrial protein genetic 1 1 1 Negative Genetic
BUD25 YER014C-A Protein involved in bud-site selection genetic 1 1 1 Positive Genetic
MNE1 YOR350C Protein involved in splicing Group I aI5-beta intron from COX1 mRNA genetic 1 1 1 Negative Genetic
ECM23 YPL021W Non-essential protein of unconfirmed function genetic 1 1 1 Negative Genetic
NPP2 YEL016C Nucleotide pyrophosphatase/phosphodiesterase genetic 1 1 1 Negative Genetic
PAU10 YDR542W Protein of unknown function genetic 1 1 1 Negative Genetic
PAU16 YKL224C Protein of unknown function genetic 1 1 1 Negative Genetic