| UBI4 |
YLL039C |
Ubiquitin |
physical |
3 |
2 |
3 |
Reconstituted Complex, Co-crystal Structure, Co-crystal Structure |
| TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| AOS1 |
YPR180W |
Subunit of heterodimeric nuclear SUMO activating enzyme E1 with Uba2p |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
| CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFG1 |
YGR186W |
TFIIF (Transcription Factor II) largest subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RVB1 |
YDR190C |
ATP-dependent DNA helicase, also known as pontin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DRS1 |
YLL008W |
Nucleolar DEAD-box protein required for ribosome assembly and function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RGT2 |
YDL138W |
Plasma membrane high glucose sensor that regulates glucose transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOC3 |
YLR002C |
Subunit of a nuclear complex with Noc2p and pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAP185 |
YJL098W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP9 |
YPR137W |
Protein involved in pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPA43 |
YOR340C |
RNA polymerase I subunit A43 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GCD2 |
YGR083C |
Delta subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP10 |
YDL031W |
Putative ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
| BUD21 |
YOR078W |
Component of small ribosomal subunit (SSU) processosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RFA1 |
YAR007C |
Subunit of heterotrimeric Replication Protein A (RPA) |
physical |
1 |
1 |
1 |
Two-hybrid |
| CTI6 |
YPL181W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DBP2 |
YNL112W |
ATP-dependent RNA helicase of the DEAD-box protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CSE1 |
YGL238W |
Nuclear envelope protein that acts as a recycling factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEN54 |
YPL083C |
Subunit of the tRNA splicing endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TAF3 |
YPL011C |
TFIID subunit (47 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCT7 |
YJL111W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TRS130 |
YMR218C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPH1 |
YPR160W |
Glycogen phosphorylase required for the mobilization of glycogen |
genetic |
1 |
1 |
1 |
Positive Genetic |
| HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PMA2 |
YPL036W |
Plasma membrane H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC9 |
YDL164C |
DNA ligase I found in nucleus and mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL30 |
YBR088C |
Proliferating cell nuclear antigen (PCNA) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ADD66 |
YKL206C |
Protein involved in 20S proteasome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSO2 |
YMR137C |
Nuclease required for DNA single- and double-strand break repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IME2 |
YJL106W |
Serine/threonine protein kinase involved in activation of meiosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RUB1 |
YDR139C |
Ubiquitin-like protein with similarity to mammalian NEDD8 |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCL5 |
YHR071W |
Cyclin |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RRN9 |
YMR270C |
Protein involved in promoting high level transcription of rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRN5 |
YLR141W |
Protein involved in transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| ENT1 |
YDL161W |
Epsin-like protein involved in endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAF1 |
YIL019W |
Protein required for pre-rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| TAO3 |
YIL129C |
Component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YRA2 |
YKL214C |
Member of the REF (RNA and export factor binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CFD1 |
YIL003W |
Highly conserved iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL40B |
YKR094C |
Ubiquitin-ribosomal 60S subunit protein L40B fusion protein |
physical |
1 |
1 |
1 |
Biochemical Activity |
| RPS31 |
YLR167W |
Fusion protein cleaved to yield ribosomal protein S31 and ubiquitin |
physical |
1 |
1 |
1 |
Biochemical Activity |
| IRC7 |
YFR055W |
Cysteine desulphydrase, enables growth on cysteine as nitrogen source |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRP15 |
YPR143W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SAS10 |
YDL153C |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MSF1 |
YPR047W |
Mitochondrial phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
| GAS3 |
YMR215W |
Putative 1,3-beta-glucanosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UTP25 |
YIL091C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YBR285W |
YBR285W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PSR2 |
YLR019W |
Putative plasma membrane phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AAD15 |
YOL165C |
Putative aryl-alcohol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VMA9 |
YCL005W-A |
Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RQC2 |
YPL009C |
Component of the Ribosome Quality Control (RQC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMF2 |
YHR050W |
Divalent metal ion transporter involved in manganese homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SNG1 |
YGR197C |
Protein involved in resistance to nitrosoguanidine and 6-azauracil |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT2 |
YHR037W |
Delta-1-pyrroline-5-carboxylate dehydrogenase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RRT6 |
YGL146C |
Integral membrane protein, member of the p24 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SOG2 |
YOR353C |
Key component of the RAM signaling network |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PEX9 |
YMR018W |
Peroxisomal membrane signal receptor for peroxisomal matrix proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ZNF1 |
YFL052W |
Zinc cluster transcription factor that regulates respiratory growth |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MIN10 |
YFR032C-B |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VBA5 |
YKR105C |
Plasma membrane protein of the Major Facilitator Superfamily (MFS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTC5 |
YDR089W |
Novel subunit of the vacuolar transporter chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YLR154C-G |
YLR154C-G |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| YML003W |
YML003W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
