TIF5 |
YPR041W |
Translation initiation factor eIF5 |
physical |
24 |
5 |
14 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Affinity Capture-MS, Reconstituted Complex, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
20 |
4 |
12 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
19 |
6 |
15 |
Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Co-fractionation, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex |
SUI1 |
YNL244C |
Translation initiation factor eIF1 |
physical |
16 |
4 |
11 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western |
TIF34 |
YMR146C |
eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
13 |
4 |
9 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
TIF35 |
YDR429C |
eIF3g subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
7 |
2 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
physical |
6 |
2 |
5 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
4 |
4 |
3 |
Reconstituted Complex, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western |
FUN12 |
YAL035W |
Translation initiation factor eIF5B |
physical |
4 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPB4 |
YJL140W |
RNA polymerase II subunit B32 |
physical |
4 |
3 |
2 |
Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Two-hybrid |
RPS0A |
YGR214W |
Ribosomal 40S subunit protein S0A |
physical |
3 |
3 |
3 |
Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS |
RLI1 |
YDR091C |
Essential Fe-S protein |
physical |
3 |
2 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SUI1 |
YNL244C |
Translation initiation factor eIF1 |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
SUI3 |
YPL237W |
Beta subunit of the translation initiation factor eIF2 |
physical |
2 |
2 |
2 |
Two-hybrid, Affinity Capture-MS |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
2 |
1 |
2 |
DNA to cDNA expression microarray evidence, DNA to cDNA expression microarray evidence |
CBF5 |
YLR175W |
Pseudouridine synthase catalytic subunit of box H/ACA snoRNPs |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS17A |
YML024W |
Ribosomal protein 51 (rp51) of the small (40s) subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS22A |
YJL190C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS7A |
YOR096W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPS9A |
YPL081W |
Protein component of the small (40S) ribosomal subunit |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
2 |
2 |
1 |
Positive Genetic, Negative Genetic |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SPT20 |
YOL148C |
Subunit of the SAGA transcriptional regulatory complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
TUP1 |
YCR084C |
General repressor of transcription in complex with Cyc8p |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CHD1 |
YER164W |
Chromatin remodeler that regulates various aspects of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CKA1 |
YIL035C |
Alpha catalytic subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Biochemical Activity |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ECM2 |
YBR065C |
Pre-mRNA splicing factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC33 |
YOL139C |
Translation initiation factor eIF4E |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ILS1 |
YBL076C |
Cytoplasmic isoleucine-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUD1 |
YBR119W |
U1 snRNP A protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DST1 |
YGL043W |
General transcription elongation factor TFIIS |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCR1 |
YLR192C |
eIF3j component of translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PRT1 |
YOR361C |
eIF3b subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUA7 |
YPR086W |
Transcription factor TFIIB |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YGL081W |
YGL081W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
physical |
1 |
1 |
1 |
Two-hybrid |
TAH1 |
YCR060W |
Component of conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YRB2 |
YIL063C |
Protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIL1 |
YGR086C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TGL5 |
YOR081C |
Bifunctional triacylglycerol lipase and LPA acyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB7 |
YDR404C |
RNA polymerase II subunit B16 |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SBP1 |
YHL034C |
Protein that binds eIF4G and has a role in repression of translation |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RLP7 |
YNL002C |
Nucleolar protein similar to large ribosomal subunit L7 proteins |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA108 |
YIL137C |
Ribosome-associated, nascent chain binding factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL16A |
YIL133C |
Ribosomal 60S subunit protein L16A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SCP160 |
YJL080C |
Essential RNA-binding G protein effector of mating response pathway |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TMA46 |
YOR091W |
Protein of unknown function that associates with translating ribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAM50 |
YNL026W |
Component of the Sorting and Assembly Machinery (SAM) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF4 |
YGL014W |
Member of the PUF protein family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
UTP10 |
YJL109C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
TIF1 |
YKR059W |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS1A |
YLR441C |
Ribosomal protein of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS10A |
YOR293W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS12 |
YOR369C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS13 |
YDR064W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS15 |
YOL040C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS18A |
YDR450W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS20 |
YHL015W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL25 |
YOL127W |
Ribosomal 60S subunit protein L25 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL26A |
YLR344W |
Ribosomal 60S subunit protein L26A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL31A |
YDL075W |
Ribosomal 60S subunit protein L31A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS3 |
YNL178W |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPS14A |
YCR031C |
Protein component of the small (40S) ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT16 |
YGL207W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPL39 |
YJL189W |
Ribosomal 60S subunit protein L39 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
TPK1 |
YJL164C |
cAMP-dependent protein kinase catalytic subunit |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Positive Genetic |
POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP11 |
YDL043C |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP5 |
YDR398W |
Subunit of U3-containing Small Subunit (SSU) processome complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRN7 |
YJL025W |
Component of the core factor (CF) rDNA transcription factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC4 |
YGR002C |
Component of the Swr1p complex that incorporates Htz1p into chromatin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUI2 |
YJR007W |
Alpha subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSL1 |
YLR005W |
Subunit of the core form of RNA polymerase transcription factor TFIIH |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL8A |
YHL033C |
Ribosomal 60S subunit protein L8A |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA4 |
YHR111W |
E1-like protein that activates Urm1p before urmylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS53 |
YJL029C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJR120W |
YJR120W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM20 |
YOR275C |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP1 |
YBL017C |
Type I transmembrane sorting receptor for multiple vacuolar hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC6 |
YCR079W |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX19 |
YDL065C |
Chaperone and import receptor for newly-synthesized class I PMPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL075C |
YKL075C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR096C |
YPR096C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR097W |
YPR097W |
Protein that contains a PX domain and binds phosphoinositides |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR050C |
YGR050C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
OPI1 |
YHL020C |
Transcriptional regulator of a variety of genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YUH1 |
YJR099W |
Ubiquitin C-terminal hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB4 |
YMR019W |
Putative transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET8 |
YNL003C |
S-adenosylmethionine transporter of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT3 |
YOR321W |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGM1 |
YKL127W |
Phosphoglucomutase, minor isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
NST1 |
YNL091W |
Translational inhibitor and suppressor of proteasome-assembly defects |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMD3 |
YLR432W |
Inosine monophosphate dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AAR2 |
YBL074C |
Component of the U5 snRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM16 |
YMR128W |
Essential DEAH-box ATP-dependent RNA helicase specific to U3 snoRNP |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN2 |
YDR283C |
Protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HAT1 |
YPL001W |
Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHF1 |
YBR009C |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
HHF2 |
YNL030W |
Histone H4 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ISW1 |
YBR245C |
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT1 |
YPL082C |
Essential protein involved in regulation of transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MLC1 |
YGL106W |
Essential light chain for Myo1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MYO4 |
YAL029C |
Type V myosin motor involved in actin-based transport of cargos |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HSP82 |
YPL240C |
Hsp90 chaperone |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTA1 |
YDR225W |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HTA1 |
YDR225W |
Histone H2A |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTA2 |
YBL003C |
Histone H2A |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS4 |
YIL112W |
Subunit of the Set3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSP1 |
YPL004C |
Eisosome core component |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CAF20 |
YOR276W |
Phosphoprotein of the mRNA cap-binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MGE1 |
YOR232W |
Mitochondrial matrix cochaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
INM1 |
YHR046C |
Inositol monophosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HIR1 |
YBL008W |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUF1 |
YOL087C |
Ubiquitin-binding protein of unknown function |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDH1 |
YGL003C |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GDS1 |
YOR355W |
Protein involved in histone H4 acetylation at ribosomal protein genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUA2 |
YOR284W |
Cytoplasmic protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
HSP10 |
YOR020C |
Mitochondrial matrix co-chaperonin |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFI1 |
YOR156C |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MIF2 |
YKL089W |
Centromeric CDEIII region binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL4 |
YPL248C |
DNA-binding transcription factor required for activating GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPA2 |
YPR193C |
Tetrameric histone acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HBS1 |
YKR084C |
GTPase with similarity to translation release factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXP1 |
YDL121C |
A cargo receptor protein for Pma1p |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
BOL3 |
YAL046C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG32 |
YIL146C |
Mitochondrial outer membrane protein required to initiate mitophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALT1 |
YLR089C |
Alanine transaminase (glutamic pyruvic transaminase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCS1 |
YDL226C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Two-hybrid |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDS2 |
YOL047C |
Protein Involved in spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIX14 |
YDR031W |
Mitochondrial intermembrane space protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCL3 |
YGL085W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM8 |
YBR076W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |