Standard name Systematic name Name description Description
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs Chaperone and import receptor for newly-synthesized class I PMPs; binds peroxisomal membrane proteins (PMPs) in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane; interacts with Myo2p and contributes to peroxisome partitioning
Visualize the interactome of PEX19
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.843 0.87 0.707
Mito 0.120 NaN NaN
Cort. Patches NaN NaN 0.051
Golgi NaN NaN 0.071
SpindlePole NaN NaN 0.051
Vac/Vac Memb NaN NaN 0.091

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 5350

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PEX19 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PEX3 YDR329C Peroxisomal membrane protein (PMP) physical 9 5 6 Affinity Capture-Western, Two-hybrid, Two-hybrid, PCA, PCA, Two-hybrid, Co-localization, Two-hybrid, Reconstituted Complex
PEX11 YOL147C Peroxisomal protein required for medium-chain fatty acid oxidation physical 6 2 6 Two-hybrid, Two-hybrid, Two-hybrid, PCA, PCA, Two-hybrid
PEX13 YLR191W Peroxisomal importomer complex component physical 5 3 4 Two-hybrid, PCA, PCA, Protein-peptide, Two-hybrid
PEX17 YNL214W Membrane peroxin of the peroxisomal importomer complex physical 4 4 3 Affinity Capture-Western, Two-hybrid, PCA, Protein-peptide
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos physical 4 4 1 Reconstituted Complex, Two-hybrid, Affinity Capture-Western, Protein-peptide
PEX25 YPL112C Peripheral peroxisomal membrane peroxin physical 3 3 3 Two-hybrid, PCA, Protein-peptide
PSK2 YOL045W PAS-domain containing serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 3 2 2 Negative Genetic, Dosage Growth Defect, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
AIM22 YJL046W Lipoate-protein ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HTD2 YHR067W Mitochondrial 3-hydroxyacyl-thioester dehydratase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LIP2 YLR239C Lipoyl ligase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin physical 2 2 2 Two-hybrid, Affinity Capture-MS
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase physical 2 2 2 PCA, Protein-peptide
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
SDS24 YBR214W Protein involved in cell separation during budding genetic 2 1 2 Negative Genetic, Negative Genetic
RIP1 YEL024W Ubiquinol-cytochrome-c reductase genetic 2 1 2 Negative Genetic, Negative Genetic
ROM1 YGR070W Guanine nucleotide exchange factor (GEF) for Rho1p genetic 2 1 2 Negative Genetic, Negative Genetic
SER2 YGR208W Phosphoserine phosphatase of the phosphoglycerate pathway genetic 2 1 2 Negative Genetic, Negative Genetic
YLR152C YLR152C Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
RAS2 YNL098C GTP-binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 2 1 2 Negative Genetic, Negative Genetic
PPT2 YPL148C Phosphopantetheine:protein transferase (PPTase) genetic 2 1 2 Negative Genetic, Negative Genetic
TMH18 YPR098C Mitochondrial protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
ARP9 YMR033W Component of both the SWI/SNF and RSC chromatin remodeling complexes genetic 2 1 2 Negative Genetic, Negative Genetic
INP2 YMR163C Peroxisome-specific receptor important for peroxisome inheritance physical 2 1 2 Two-hybrid, Two-hybrid
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 2 Negative Genetic, Negative Genetic
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 2 1 2 Negative Genetic, Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 2 1 2 Negative Genetic, Negative Genetic
IRA2 YOL081W GTPase-activating protein genetic 2 1 2 Negative Genetic, Negative Genetic
KDX1 YKL161C Protein kinase genetic 2 1 2 Negative Genetic, Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 2 1 2 Negative Genetic, Negative Genetic
LUG1 YLR352W Protein of unknown function with similarity to F-box proteins genetic 2 1 2 Negative Genetic, Negative Genetic
PEX14 YGL153W Central component of the peroxisomal importomer complex physical 2 1 2 PCA, PCA
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase genetic 2 1 2 Positive Genetic, Positive Genetic
PEX12 YMR026C C3HC4-type RING-finger peroxin and E3 ubiquitin ligase genetic 2 1 2 Positive Genetic, Positive Genetic
ARP6 YLR085C Actin-related protein that binds nucleosomes genetic 2 1 2 Negative Genetic, Negative Genetic
HOS1 YPR068C Class I histone deacetylase (HDAC) family member genetic 2 1 2 Negative Genetic, Negative Genetic
ERV41 YML067C Protein localized to COPII-coated vesicles genetic 2 1 2 Negative Genetic, Negative Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 2 1 2 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 2 Negative Genetic, Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 2 1 2 Positive Genetic, Positive Genetic
CLB4 YLR210W B-type cyclin involved in cell cycle progression genetic 2 1 2 Negative Genetic, Negative Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 2 1 2 Negative Genetic, Negative Genetic
KIP3 YGL216W Kinesin-related antiparallel sliding motor protein genetic 2 1 2 Negative Genetic, Negative Genetic
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase genetic 2 1 2 Negative Genetic, Negative Genetic
MRX12 YJR003C Protein that associates with mitochondrial ribosome genetic 2 1 2 Negative Genetic, Negative Genetic
MRPL50 YNR022C Mitochondrial ribosomal protein of the large subunit genetic 2 1 2 Negative Genetic, Negative Genetic
IRC20 YLR247C E3 ubiquitin ligase and putative helicase genetic 2 1 2 Negative Genetic, Negative Genetic
ARP3 YJR065C Essential component of the Arp2/3 complex genetic 2 2 1 Positive Genetic, Negative Genetic
ANT1 YPR128C Peroxisomal adenine nucleotide transporter physical 2 2 1 Protein-peptide, Two-hybrid
SPT8 YLR055C Subunit of the SAGA transcriptional regulatory complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 2 1 1 Negative Genetic, Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 2 1 1 Negative Genetic, Negative Genetic
PAM18 YLR008C Subunit of the import motor (PAM complex) genetic 2 1 1 Negative Genetic, Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia regulation 1 1 1 DNA to cDNA expression microarray evidence
XBP1 YIL101C Transcriptional repressor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
TFC7 YOR110W RNA pol III transcription initiation factor complex (TFIIIC) subunit regulation 1 1 1 chromatin immunoprecipitation-chip evidence
MMS21 YEL019C Highly conserved SUMO E3 ligase subunit of SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 1 1 1 Positive Genetic
MAK16 YAL025C Essential nuclear protein genetic 1 1 1 Negative Genetic
NOP2 YNL061W rRNA m5C methyltransferase genetic 1 1 1 Positive Genetic
RIX7 YLL034C Putative ATPase of the AAA family physical 1 1 1 Affinity Capture-MS
YKU70 YMR284W Subunit of the telomeric Ku complex (Yku70p-Yku80p) physical 1 1 1 Affinity Capture-MS
RGR1 YLR071C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
PEX3 YDR329C Peroxisomal membrane protein (PMP) genetic 1 1 1 Positive Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis physical 1 1 1 Two-hybrid
PEX32 YBR168W Peroxisomal integral membrane protein physical 1 1 1 Two-hybrid
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting physical 1 1 1 Two-hybrid
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins physical 1 1 1 PCA
PEX22 YAL055W Putative peroxisomal membrane protein physical 1 1 1 PCA
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Positive Genetic
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase physical 1 1 1 PCA
PEX2 YJL210W RING-finger peroxin and E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
TPK2 YPL203W cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Reconstituted Complex
TGL3 YMR313C Bifunctional triacylglycerol lipase and LPE acyltransferase physical 1 1 1 PCA
PLN1 YKR046C Perilipin, involved in formation and stability of lipid droplets physical 1 1 1 PCA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
PEX27 YOR193W Peripheral peroxisomal membrane protein physical 1 1 1 Protein-peptide
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PEX35 YGR168C Regulator of peroxisome abundance physical 1 1 1 PCA
PEX19 YDL065C Chaperone and import receptor for newly-synthesized class I PMPs physical 1 1 1 PCA
SLX1 YBR228W Endonuclease involved in DNA recombination and repair genetic 1 1 1 Negative Genetic
QCR6 YFR033C Subunit 6 of the ubiquinol cytochrome-c reductase complex genetic 1 1 1 Negative Genetic
USE1 YGL098W Essential SNARE protein localized to the ER genetic 1 1 1 Positive Genetic
SPR3 YGR059W Sporulation-specific homolog of the CDC3/10/11/12 family of genes genetic 1 1 1 Negative Genetic
PTH1 YHR189W One of two mitochondrially-localized peptidyl-tRNA hydrolases genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
RSC2 YLR357W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Negative Genetic
PLB3 YOL011W Phospholipase B (lysophospholipase) involved in lipid metabolism genetic 1 1 1 Negative Genetic
SPO19 YPL130W Meiosis-specific prospore protein genetic 1 1 1 Positive Genetic
RNY1 YPL123C Vacuolar RNase of the T(2) family genetic 1 1 1 Negative Genetic
PRP4 YPR178W Splicing factor genetic 1 1 1 Positive Genetic
PEX6 YNL329C AAA-peroxin genetic 1 1 1 Positive Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Positive Genetic
PEX8 YGR077C Intraperoxisomal organizer of the peroxisomal import machinery genetic 1 1 1 Positive Genetic
TVP18 YMR071C Integral membrane protein genetic 1 1 1 Positive Genetic
REB1 YBR049C RNA polymerase I enhancer binding protein genetic 1 1 1 Positive Genetic
SRM1 YGL097W Nucleotide exchange factor for Gsp1p genetic 1 1 1 Positive Genetic
TAM41 YGR046W Mitochondrial phosphatidate cytidylyltransferase (CDP-DAG synthase) genetic 1 1 1 Positive Genetic
PRP31 YGR091W Splicing factor genetic 1 1 1 Positive Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Positive Genetic
TIF34 YMR146C eIF3i subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Positive Genetic
RPL3 YOR063W Ribosomal 60S subunit protein L3 genetic 1 1 1 Positive Genetic
SGV1 YPR161C Cyclin (Bur2p)-dependent protein kinase genetic 1 1 1 Positive Genetic
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme genetic 1 1 1 Positive Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Positive Genetic
PIR1 YKL164C O-glycosylated protein required for cell wall stability genetic 1 1 1 Positive Genetic
TVP38 YKR088C Integral membrane protein genetic 1 1 1 Positive Genetic
YMR175W-A YMR175W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
PHM7 YOL084W Protein of unknown function genetic 1 1 1 Positive Genetic
PIN2 YOR104W Exomer-dependent cargo protein genetic 1 1 1 Positive Genetic
SPS4 YOR313C Protein whose expression is induced during sporulation genetic 1 1 1 Positive Genetic
SSN3 YPL042C Component of the RNA polymerase II mediator complex genetic 1 1 1 Positive Genetic
SPO24 YPR036W-A Small (67 amino acids) protein involved in sporulation genetic 1 1 1 Positive Genetic
POL30 YBR088C Proliferating cell nuclear antigen (PCNA) genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
SNM1 YDR478W Ribonuclease MRP complex subunit genetic 1 1 1 Negative Genetic
SCC4 YER147C Subunit of cohesin loading factor (Scc2p-Scc4p) genetic 1 1 1 Negative Genetic
RSC8 YFR037C Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
RPS2 YGL123W Protein component of the small (40S) subunit genetic 1 1 1 Negative Genetic
VHT1 YGR065C High-affinity plasma membrane H+-biotin (vitamin H) symporter genetic 1 1 1 Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Negative Genetic
RPS20 YHL015W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
UTP9 YHR196W Nucleolar protein genetic 1 1 1 Negative Genetic
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat genetic 1 1 1 Negative Genetic
TIM54 YJL054W Component of the mitochondrial TIM22 complex genetic 1 1 1 Negative Genetic
YAE1 YJR067C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
SNU114 YKL173W GTPase component of U5 snRNP involved in mRNA splicing via spliceosome genetic 1 1 1 Negative Genetic
UBA1 YKL210W Ubiquitin activating enzyme (E1) genetic 1 1 1 Negative Genetic
TFA2 YKR062W TFIIE small subunit genetic 1 1 1 Negative Genetic
SEC10 YLR166C Essential 100kDa subunit of the exocyst complex genetic 1 1 1 Negative Genetic
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
TIF11 YMR260C Translation initiation factor eIF1A genetic 1 1 1 Negative Genetic
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci genetic 1 1 1 Negative Genetic
POP1 YNL221C Subunit of RNase MRP, nuclear RNase P and telomerase complexes genetic 1 1 1 Negative Genetic
RAT1 YOR048C Nuclear 5' to 3' single-stranded RNA exonuclease genetic 1 1 1 Negative Genetic
SWI1 YPL016W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
TIM50 YPL063W Essential component of the TIM23 complex genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
UTP6 YDR449C Nucleolar protein genetic 1 1 1 Negative Genetic
PRP43 YGL120C RNA helicase in the DEAH-box family genetic 1 1 1 Negative Genetic
PRP19 YLL036C Splicing factor associated with the spliceosome genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Negative Genetic
YBR298C-A YBR298C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
PST1 YDR055W Cell wall protein that contains a putative GPI-attachment site genetic 1 1 1 Negative Genetic
TMN2 YDR107C Protein with a role in cellular adhesion and filamentous growth genetic 1 1 1 Negative Genetic
YDR131C YDR131C F-box protein subunit of SCF ubiquitin ligase complex genetic 1 1 1 Negative Genetic
TCA17 YEL048C Component of transport protein particle (TRAPP) complex II genetic 1 1 1 Negative Genetic
WWM1 YFL010C WW domain containing protein of unknown function genetic 1 1 1 Negative Genetic
SAP155 YFR040W Protein required for function of the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
RMD8 YFR048W Cytosolic protein required for sporulation genetic 1 1 1 Negative Genetic
SUT1 YGL162W Zn(II)2Cys6 family transcription factor genetic 1 1 1 Negative Genetic
STR3 YGL184C Peroxisomal cystathionine beta-lyase genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
PUS6 YGR169C tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
TIM13 YGR181W Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
YGR240C-A YGR240C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
TDA11 YHR159W Putative protein of unknown function genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
PPX1 YHR201C Exopolyphosphatase genetic 1 1 1 Negative Genetic
POG1 YIL122W DNA-binding transcriptional activator genetic 1 1 1 Negative Genetic
TRK1 YJL129C Component of the Trk1p-Trk2p potassium transport system genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
SAM1 YLR180W S-adenosylmethionine synthetase genetic 1 1 1 Negative Genetic
YLR285C-A YLR285C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
RPS25B YLR333C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWC7 YLR385C Protein of unknown function genetic 1 1 1 Negative Genetic
YLR412C-A YLR412C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 1 1 1 Negative Genetic
RPL36A YMR194W Ribosomal 60S subunit protein L36A genetic 1 1 1 Negative Genetic
SSN8 YNL025C Cyclin-like component of RNA polymerase II holoenzyme genetic 1 1 1 Negative Genetic
RNH201 YNL072W Ribonuclease H2 catalytic subunit genetic 1 1 1 Negative Genetic
SWS2 YNL081C Putative mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
UBP10 YNL186W Ubiquitin-specific protease, deubiquitinates Ub-protein moieties genetic 1 1 1 Negative Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Negative Genetic
RCF2 YNR018W Cytochrome c oxidase subunit genetic 1 1 1 Negative Genetic
YOL038C-A YOL038C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOL057W YOL057W Dipeptidyl-peptidase III genetic 1 1 1 Negative Genetic
TRM10 YOL093W tRNA methyltransferase genetic 1 1 1 Negative Genetic
PTH4 YOL114C Protein similar to the human peptidyl-tRNA hydrolase gene ICT1 genetic 1 1 1 Negative Genetic
TRM11 YOL124C Catalytic subunit of adoMet-dependent tRNA methyltransferase complex genetic 1 1 1 Negative Genetic
YOR008C-A YOR008C-A Putative protein of unknown function genetic 1 1 1 Negative Genetic
YOR131C YOR131C Putative haloacid dehalogenase-like hydrolase genetic 1 1 1 Negative Genetic
YOR296W YOR296W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SRL4 YPL033C Protein of unknown function genetic 1 1 1 Negative Genetic
SSU1 YPL092W Plasma membrane sulfite pump involved in sulfite metabolism genetic 1 1 1 Negative Genetic
YPL191C YPL191C K48-specific deubiquitinating (DUB) enzyme genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
LTO1 YNL260C Substrate-specific adaptor protein involved in apo-Rli1p maturation genetic 1 1 1 Negative Genetic
NOC3 YLR002C Subunit of a nuclear complex with Noc2p and pre-replicative complexes genetic 1 1 1 Negative Genetic
NOP56 YLR197W Essential evolutionarily-conserved nucleolar protein genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-MS
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity genetic 1 1 1 Negative Genetic
PAB1 YER165W Poly(A) binding protein genetic 1 1 1 Negative Genetic
IML1 YJR138W GTPase-activating protein (GAP) subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CSL4 YNL232W Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
NIP1 YMR309C eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Positive Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
KAP104 YBR017C Transportin or cytosolic karyopherin beta 2 genetic 1 1 1 Positive Genetic
BMS1 YPL217C GTPase required for ribosomal subunit synthesis and rRNA processing genetic 1 1 1 Negative Genetic
APL3 YBL037W Alpha-adaptin genetic 1 1 1 Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 1 1 1 Positive Genetic
BMH2 YDR099W 14-3-3 protein, minor isoform genetic 1 1 1 Negative Genetic
AIM21 YIR003W Subunit of a complex that associates with actin filaments genetic 1 1 1 Negative Genetic
CDC14 YFR028C Protein phosphatase required for mitotic exit genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
BNI1 YNL271C Formin physical 1 1 1 Reconstituted Complex
AVO1 YOL078W Component of the membrane-bound TORC2 complex genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
ESP1 YGR098C Separase/separin, a caspase-like cysteine protease genetic 1 1 1 Dosage Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
KGD1 YIL125W Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex genetic 1 1 1 Negative Genetic
KGD2 YDR148C Dihydrolipoyl transsuccinylase genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MRP13 YGR084C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
HRR25 YPL204W Conserved casein kinase, monopolin subunit physical 1 1 1 Affinity Capture-MS
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
MTR10 YOR160W Nuclear import receptor genetic 1 1 1 Negative Genetic
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Positive Genetic
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Two-hybrid
AFG2 YLR397C ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
LPD1 YFL018C Dihydrolipoamide dehydrogenase genetic 1 1 1 Negative Genetic
PDA1 YER178W E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
BLM10 YFL007W Proteasome activator genetic 1 1 1 Negative Genetic
MDS3 YGL197W Putative component of the TOR regulatory pathway genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
MRPL6 YHR147C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
CCT2 YIL142W Subunit beta of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Positive Genetic
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B genetic 1 1 1 Negative Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Positive Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
HYP2 YEL034W Translation elongation factor eIF-5A genetic 1 1 1 Negative Genetic
DCS1 YLR270W Non-essential hydrolase involved in mRNA decapping genetic 1 1 1 Positive Genetic
FAA4 YMR246W Long chain fatty acyl-CoA synthetase physical 1 1 1 PCA
GLC8 YMR311C Regulatory subunit of protein phosphatase 1 (Glc7p) genetic 1 1 1 Negative Genetic
GPD2 YOL059W NAD-dependent glycerol 3-phosphate dehydrogenase genetic 1 1 1 Negative Genetic
PBR1 YNL181W Putative oxidoreductase genetic 1 1 1 Positive Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 1 1 1 Positive Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Positive Genetic
GPP2 YER062C DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
ERG6 YML008C Delta(24)-sterol C-methyltransferase physical 1 1 1 PCA
HYM1 YKL189W Component of the RAM signaling network physical 1 1 1 Affinity Capture-MS
PDX1 YGR193C E3-binding protein of the mitochondrial pyruvate dehydrogenase complex genetic 1 1 1 Negative Genetic
GIS4 YML006C CAAX box containing protein of unknown function genetic 1 1 1 Negative Genetic
HHO1 YPL127C Histone H1, linker histone with roles in meiosis and sporulation genetic 1 1 1 Negative Genetic
CTF4 YPR135W Chromatin-associated protein genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Negative Genetic
ILV2 YMR108W Acetolactate synthase physical 1 1 1 Affinity Capture-MS
ATG4 YNL223W Conserved cysteine protease required for autophagy genetic 1 1 1 Negative Genetic
NOP53 YPL146C Nucleolar protein genetic 1 1 1 Negative Genetic
PAP2 YOL115W Non-canonical poly(A) polymerase genetic 1 1 1 Positive Genetic
FZO1 YBR179C Mitofusin, protein involved in mitochondrial outer membrane fusion physical 1 1 1 Affinity Capture-Western
HMG2 YLR450W HMG-CoA reductase genetic 1 1 1 Negative Genetic
DEF1 YKL054C RNAPII degradation factor physical 1 1 1 Affinity Capture-MS
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
FMP48 YGR052W Putative protein of unknown function physical 1 1 1 Reconstituted Complex
BIM1 YER016W Microtubule plus end-tracking protein genetic 1 1 1 Negative Genetic
ATG19 YOL082W Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway genetic 1 1 1 Negative Genetic
GCN4 YEL009C bZIP transcriptional activator of amino acid biosynthetic genes genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
NUP57 YGR119C FG-nucleoporin component of central core of the nuclear pore complex physical 1 1 1 Two-hybrid
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Negative Genetic
IKS1 YJL057C Protein kinase of unknown cellular role physical 1 1 1 Reconstituted Complex
PEX14 YGL153W Central component of the peroxisomal importomer complex genetic 1 1 1 Positive Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Positive Genetic
FIS1 YIL065C Protein involved in mitochondrial fission and peroxisome abundance physical 1 1 1 Reconstituted Complex
NPR2 YEL062W Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Positive Genetic
PEX10 YDR265W Peroxisomal membrane E3 ubiquitin ligase physical 1 1 1 PCA
PEX13 YLR191W Peroxisomal importomer complex component genetic 1 1 1 Positive Genetic
GRC3 YLL035W Polynucleotide kinase present on rDNA genetic 1 1 1 Negative Genetic
NFI1 YOR156C SUMO E3 ligase genetic 1 1 1 Negative Genetic
MRS1 YIR021W Splicing protein genetic 1 1 1 Negative Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Negative Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Positive Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Negative Genetic
CTK2 YJL006C Beta subunit of C-terminal domain kinase I (CTDK-I) physical 1 1 1 Reconstituted Complex
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
MOB1 YIL106W Component of the mitotic exit network genetic 1 1 1 Negative Genetic
FCP1 YMR277W Carboxy-terminal domain (CTD) phosphatase genetic 1 1 1 Positive Genetic
GIC2 YDR309C Rho-family GTPase interacting protein and Cdc42p effector genetic 1 1 1 Negative Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 1 1 1 Negative Genetic
COX19 YLL018C-A Protein required for cytochrome c oxidase assembly genetic 1 1 1 Negative Genetic
MDM31 YHR194W Mitochondrial protein that may have a role in phospholipid metabolism genetic 1 1 1 Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane genetic 1 1 1 Negative Genetic
APM2 YHL019C Protein of unknown function genetic 1 1 1 Negative Genetic
ARR3 YPR201W Plasma membrane metalloid/H+ antiporter genetic 1 1 1 Negative Genetic
MIG2 YGL209W Zinc finger transcriptional repressor genetic 1 1 1 Negative Genetic
HUL4 YJR036C Protein with similarity to hect domain E3 ubiquitin-protein ligases genetic 1 1 1 Negative Genetic
PEX1 YKL197C AAA-peroxin genetic 1 1 1 Positive Genetic
BTT1 YDR252W Heterotrimeric nascent polypeptide-associated complex beta3 subunit genetic 1 1 1 Negative Genetic
HSP12 YFL014W Plasma membrane protein involved in maintaining membrane organization genetic 1 1 1 Negative Genetic
ASE1 YOR058C Mitotic spindle midzone-localized microtubule bundling protein genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
COI1 YDR381C-A Mitochondrial assembly factor genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
FCF2 YLR051C Nucleolar protein involved in the early steps of 35S rRNA processing genetic 1 1 1 Negative Genetic
PAM1 YDR251W Essential protein of unknown function genetic 1 1 1 Negative Genetic
MRPL17 YNL252C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GID11 YLR149C Substrate receptor of the glucose-induced degradation-deficient (GID) genetic 1 1 1 Negative Genetic
BNA1 YJR025C 3-hydroxyanthranilic acid dioxygenase genetic 1 1 1 Negative Genetic
IRC3 YDR332W Double-stranded DNA-dependent helicase of the DExH/D-box family genetic 1 1 1 Negative Genetic
NOP19 YGR251W Ribosome biogenesis factor genetic 1 1 1 Negative Genetic
MMF1 YIL051C Mitochondrial protein required for transamination of isoleucine genetic 1 1 1 Negative Genetic
PDR10 YOR328W ATP-binding cassette (ABC) transporter genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
CTP1 YBR291C Mitochondrial inner membrane citrate transporter genetic 1 1 1 Negative Genetic
LOT6 YLR011W FMN-dependent NAD(P)H:quinone reductase genetic 1 1 1 Negative Genetic
CAJ1 YER048C Nuclear type II J heat shock protein of the E. coli dnaJ family genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites genetic 1 1 1 Negative Genetic
LEU9 YOR108W Alpha-isopropylmalate synthase II (2-isopropylmalate synthase) genetic 1 1 1 Negative Genetic
LIP5 YOR196C Protein involved in biosynthesis of the coenzyme lipoic acid genetic 1 1 1 Negative Genetic
NPT1 YOR209C Nicotinate phosphoribosyltransferase genetic 1 1 1 Synthetic Growth Defect
MRS2 YOR334W Mitochondrial inner membrane Mg(2+) channel genetic 1 1 1 Negative Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Positive Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 1 1 1 Negative Genetic
MPA43 YNL249C Protein of unknown function genetic 1 1 1 Negative Genetic
GEM1 YAL048C Outer mitochondrial membrane GTPase, subunit of the ERMES complex physical 1 1 1 Reconstituted Complex
CSA1 YPR174C Protein of unknown function genetic 1 1 1 Negative Genetic
OCA5 YHL029C Cytoplasmic protein required for replication of Brome mosaic virus genetic 1 1 1 Negative Genetic
APJ1 YNL077W Hsp40 chaperone with a role in SUMO-mediated protein degradation genetic 1 1 1 Negative Genetic
CYC3 YAL039C Cytochrome c heme lyase (holocytochrome c synthase) genetic 1 1 1 Negative Genetic
FRE8 YLR047C Protein with sequence similarity to iron/copper reductases genetic 1 1 1 Negative Genetic
LAG1 YHL003C Ceramide synthase component genetic 1 1 1 Negative Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Negative Genetic
OSH6 YKR003W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
HVG1 YER039C Protein of unknown function genetic 1 1 1 Negative Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
COA1 YIL157C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 1 1 1 Negative Genetic
ERP4 YOR016C Member of the p24 family involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
INO1 YJL153C Inositol-3-phosphate synthase genetic 1 1 1 Negative Genetic
MOT3 YMR070W Transcriptional repressor, activator genetic 1 1 1 Negative Genetic
MRN1 YPL184C RNA-binding protein that may be involved in translational regulation genetic 1 1 1 Negative Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
EDC1 YGL222C RNA-binding protein that activates mRNA decapping directly genetic 1 1 1 Negative Genetic
BSC4 YNL269W Protein of unknown function genetic 1 1 1 Negative Genetic
MIC27 YNL100W Component of the MICOS complex genetic 1 1 1 Negative Genetic
MPC2 YHR162W Highly conserved subunit of the mitochondrial pyruvate carrier (MPC) genetic 1 1 1 Negative Genetic
DPI8 YJL133C-A Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
KNH1 YDL049C Protein with similarity to Kre9p genetic 1 1 1 Synthetic Lethality
LDO16 YMR148W Protein of unknown function with possible role in spore wall assembly physical 1 1 1 PCA
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 1 1 1 Synthetic Lethality
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
MFM1 YPL060W Mitochondrial inner membrane magnesium transporter genetic 1 1 1 Negative Genetic
EMC2 YJR088C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
ENV9 YOR246C Conserved oxidoreductase involved in lipid droplet morphology genetic 1 1 1 Negative Genetic
NPR3 YHL023C Subunit of the Iml1p/SEACIT complex genetic 1 1 1 Negative Genetic
CBT1 YKL208W Protein involved in 5' RNA end processing genetic 1 1 1 Negative Genetic
OAR1 YKL055C Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase genetic 1 1 1 Negative Genetic
NAR1 YNL240C Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery genetic 1 1 1 Negative Genetic
MSH1 YHR120W DNA-binding protein of the mitochondria genetic 1 1 1 Negative Genetic
PAN6 YIL145C Pantothenate synthase genetic 1 1 1 Positive Genetic
GYP8 YFL027C GTPase-activating protein for yeast Rab family members genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
MSC6 YOR354C Multicopy suppressor of HER2 involved in mitochondrial translation genetic 1 1 1 Negative Genetic
ODC2 YOR222W Mitochondrial inner membrane transporter genetic 1 1 1 Negative Genetic
OXR1 YPL196W Protein involved in regulation of vacuolar V-ATPase genetic 1 1 1 Negative Genetic
LEU5 YHR002W Mitochondrial carrier protein genetic 1 1 1 Negative Genetic
FHN1 YGR131W Protein of unknown function genetic 1 1 1 Negative Genetic
MIN10 YFR032C-B Mitochondrial protein of unknown function genetic 1 1 1 Positive Genetic