Standard name | Systematic name | Name description | Description |
---|---|---|---|
TGL3 | YMR313C | Bifunctional triacylglycerol lipase and LPE acyltransferase | Bifunctional triacylglycerol lipase and LPE acyltransferase; major lipid particle-localized triacylglycerol (TAG) lipase; catalyzes acylation of lysophosphatidylethanolamine (LPE), a function which is essential for sporulation; protein level and stability of Tgl3p are markedly reduced in the absence of lipid droplets; required with Tgl4p for timely bud formation |
Cell cycle phase and timing of transcription peak
Cell cycle phase | Time (min) |
---|---|
CYCLoPs localization & abundance
WT1 | WT2 | WT3 | |
---|---|---|---|
Endosome | 0.165 | 0.188 | 0.268 |
Mito | 0.377 | 0.392 | 0.109 |
Nucleolus | 0.217 | 0.174 | 0.132 |
Peroxisome | 0.453 | 0.420 | 0.355 |
SpindlePole | 0.349 | 0.205 | 0.445 |
GFP localization & abundance
GFP localization | GFP abundance |
---|---|
punctate composite, lipid particle | 3210 |
GO term count
Metabolism | Cell cycle | Cell division | Signal transduction | DNA replication | |
---|---|---|---|---|---|
TGL3 | 3 | 0 | 2 | 0 | 0 |
Enzyme information
Catalyzed reactions in Yeast8 |
---|
r_3302 (DAG lipase (1-18:0, 2-18:1), lipid particle), r_3282 (TAG lipase (1-16:0, 2-18:1, 3-18:0), lipid particle), r_3287 (TAG lipase (1-16:1, 2-18:1, 3-18:1), lipid particle), r_3315 (lysoPE (1-18:1) oleoyl-CoA acyltransferase, lipid particle), r_3268 (TAG lipase (1-16:1, 2-16:1, 3-16:0), lipid particle), r_3292 (TAG lipase (1-18:1, 2-18:1, 3-16:0), lipid particle), r_3297 (DAG lipase (1-16:1, 2-16:1), lipid particle), r_3303 (DAG lipase (1-18:1, 2-18:1), lipid particle), r_3273 (TAG lipase (1-18:0, 2-16:1, 3-16:1), lipid particle), r_3296 (DAG lipase (1-16:0, 2-16:1), lipid particle), r_3278 (TAG lipase (1-18:1, 2-16:1, 3-18:0), lipid particle), r_3283 (TAG lipase (1-16:0, 2-18:1, 3-18:1), lipid particle), r_3264 (TAG lipase (1-16:0, 2-16:1, 3-16:0), lipid particle), r_3288 (TAG lipase (1-18:0, 2-18:1, 3-16:0), lipid particle), r_3298 (DAG lipase (1-18:0, 2-16:1), lipid particle), r_3269 (TAG lipase (1-16:1, 2-16:1, 3-16:1), lipid particle), r_3293 (TAG lipase (1-18:1, 2-18:1, 3-16:1), lipid particle), r_3274 (TAG lipase (1-18:0, 2-16:1, 3-18:0), lipid particle), r_3279 (TAG lipase (1-18:1, 2-16:1, 3-18:1), lipid particle), r_3284 (TAG lipase (1-16:1, 2-18:1, 3-16:0), lipid particle), r_3299 (DAG lipase (1-18:1, 2-16:1), lipid particle), r_3265 (TAG lipase (1-16:0, 2-16:1, 3-16:1), lipid particle), r_3289 (TAG lipase (1-18:0, 2-18:1, 3-16:1), lipid particle), r_3270 (TAG lipase (1-16:1, 2-16:1, 3-18:0), lipid particle), r_3294 (TAG lipase (1-18:1, 2-18:1, 3-18:0), lipid particle), r_3277 (TAG lipase (1-18:1, 2-16:1, 3-16:1), lipid particle), r_3275 (TAG lipase (1-18:0, 2-16:1, 3-18:1), lipid particle), r_3280 (TAG lipase (1-16:0, 2-18:1, 3-16:0), lipid particle), r_3312 (lysoPE (1-16:0) oleoyl-CoA acyltransferase, lipid particle), r_3300 (DAG lipase (1-16:0, 2-18:1), lipid particle), r_3285 (TAG lipase (1-16:1, 2-18:1, 3-16:1), lipid particle), r_3266 (TAG lipase (1-16:0, 2-16:1, 3-18:0), lipid particle), r_3290 (TAG lipase (1-18:0, 2-18:1, 3-18:0), lipid particle), r_3271 (TAG lipase (1-16:1, 2-16:1, 3-18:1), lipid particle), r_3295 (TAG lipase (1-18:1, 2-18:1, 3-18:1), lipid particle), r_3313 (lysoPE (1-16:1) oleoyl-CoA acyltransferase, lipid particle), r_3276 (TAG lipase (1-18:1, 2-16:1, 3-16:0), lipid particle), r_3301 (DAG lipase (1-16:1, 2-18:1), lipid particle), r_3281 (TAG lipase (1-16:0, 2-18:1, 3-16:1), lipid particle), r_3286 (TAG lipase (1-16:1, 2-18:1, 3-18:0), lipid particle), r_3291 (TAG lipase (1-18:0, 2-18:1, 3-18:1), lipid particle), r_3267 (TAG lipase (1-16:0, 2-16:1, 3-18:1), lipid particle), r_3314 (lysoPE (1-18:0) oleoyl-CoA acyltransferase, lipid particle), r_3272 (TAG lipase (1-18:0, 2-16:1, 3-16:0), lipid particle) |
List of interactors
Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.Standard name | Systematic name | Name description | Type | #Experiments | #Methods | #Publications | Evidence |
---|---|---|---|---|---|---|---|
MGA2 | YIR033W | ER membrane protein involved in regulation of OLE1 transcription | genetic | 4 | 1 | 2 | Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
TGL4 | YKR089C | Multifunctional lipase/hydrolase/phospholipase | genetic | 3 | 2 | 2 | Phenotypic Enhancement, Synthetic Growth Defect, Phenotypic Enhancement |
RIC1 | YLR039C | Protein involved in retrograde transport to the cis-Golgi network | genetic | 3 | 1 | 2 | Positive Genetic, Positive Genetic, Positive Genetic |
OPI3 | YJR073C | Methylene-fatty-acyl-phospholipid synthase | genetic | 3 | 1 | 2 | Positive Genetic, Positive Genetic, Positive Genetic |
GAS1 | YMR307W | Beta-1,3-glucanosyltransferase required for cell wall assembly | genetic | 2 | 1 | 2 | Synthetic Lethality, Synthetic Lethality |
FAR10 | YLR238W | Protein involved in recovery from arrest in response to pheromone | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
PEX5 | YDR244W | Peroxisomal membrane signal receptor for peroxisomal matrix proteins | genetic | 2 | 1 | 2 | Positive Genetic, Positive Genetic |
MNE1 | YOR350C | Protein involved in splicing Group I aI5-beta intron from COX1 mRNA | genetic | 2 | 1 | 2 | Negative Genetic, Negative Genetic |
ATG15 | YCR068W | Phospholipase | genetic | 2 | 2 | 1 | Phenotypic Suppression, Synthetic Rescue |
RGP1 | YDR137W | Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) | genetic | 2 | 1 | 1 | Positive Genetic, Positive Genetic |
LPP1 | YDR503C | Lipid phosphate phosphatase | genetic | 2 | 1 | 1 | Positive Genetic, Positive Genetic |
ALD6 | YPL061W | Cytosolic aldehyde dehydrogenase | genetic | 2 | 1 | 1 | Negative Genetic, Negative Genetic |
TSC3 | YBR058C-A | Protein that stimulates the activity of serine palmitoyltransferase | genetic | 2 | 1 | 1 | Positive Genetic, Positive Genetic |
SPF1 | YEL031W | P-type ATPase, ion transporter of the ER membrane | genetic | 2 | 1 | 1 | Positive Genetic, Positive Genetic |
SPT10 | YJL127C | Histone H3 acetylase with a role in transcriptional regulation | regulation | 1 | 1 | 1 | quantitative reverse transcription polymerase chain reaction evidence |
BUR6 | YER159C | Subunit of a heterodimeric NC2 transcription regulator complex | regulation | 1 | 1 | 1 | chromatin immunoprecipitation-chip evidence |
PEX19 | YDL065C | Chaperone and import receptor for newly-synthesized class I PMPs | physical | 1 | 1 | 1 | PCA |
RAT1 | YOR048C | Nuclear 5' to 3' single-stranded RNA exonuclease | genetic | 1 | 1 | 1 | Negative Genetic |
PRP40 | YKL012W | U1 snRNP protein involved in splicing | physical | 1 | 1 | 1 | Protein-peptide |
RPN1 | YHR027C | Non-ATPase base subunit of the 19S RP of the 26S proteasome | genetic | 1 | 1 | 1 | Negative Genetic |
RPN8 | YOR261C | Essential non-ATPase regulatory subunit of the 26S proteasome | genetic | 1 | 1 | 1 | Negative Genetic |
CCR4 | YAL021C | Component of the CCR4-NOT transcriptional complex | physical | 1 | 1 | 1 | Affinity Capture-RNA |
REB1 | YBR049C | RNA polymerase I enhancer binding protein | genetic | 1 | 1 | 1 | Positive Genetic |
ARC15 | YIL062C | Subunit of the ARP2/3 complex | physical | 1 | 1 | 1 | PCA |
CDC28 | YBR160W | Cyclin-dependent kinase (CDK) catalytic subunit | genetic | 1 | 1 | 1 | Phenotypic Suppression |
CDC55 | YGL190C | Regulatory subunit B of protein phosphatase 2A (PP2A) | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
COX5A | YNL052W | Subunit Va of cytochrome c oxidase | genetic | 1 | 1 | 1 | Negative Genetic |
DHH1 | YDL160C | Cytoplasmic DEAD-box helicase and mRNA decapping activator | physical | 1 | 1 | 1 | Affinity Capture-RNA |
ISW1 | YBR245C | ATPase subunit of imitation-switch (ISWI) class chromatin remodelers | physical | 1 | 1 | 1 | Affinity Capture-RNA |
IMG2 | YCR071C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic |
MRPL24 | YMR193W | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic |
PRP4 | YPR178W | Splicing factor | genetic | 1 | 1 | 1 | Negative Genetic |
MRPL6 | YHR147C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic |
SIN3 | YOL004W | Component of both the Rpd3S and Rpd3L histone deacetylase complexes | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
BZZ1 | YHR114W | SH3 domain protein implicated in regulating actin polymerization | physical | 1 | 1 | 1 | Two-hybrid |
SLA1 | YBL007C | Cytoskeletal protein binding protein | physical | 1 | 1 | 1 | Two-hybrid |
PHO85 | YPL031C | Cyclin-dependent kinase | physical | 1 | 1 | 1 | Biochemical Activity |
AYR1 | YIL124W | Bifunctional triacylglycerol lipase and 1-acyl DHAP reductase | physical | 1 | 1 | 1 | PCA |
ILV3 | YJR016C | Dihydroxyacid dehydratase | genetic | 1 | 1 | 1 | Negative Genetic |
GPP2 | YER062C | DL-glycerol-3-phosphate phosphatase involved in glycerol biosynthesis | genetic | 1 | 1 | 1 | Negative Genetic |
SGS1 | YMR190C | RecQ family nucleolar DNA helicase | genetic | 1 | 1 | 1 | Negative Genetic |
SWE1 | YJL187C | Protein kinase that regulates the G2/M transition | genetic | 1 | 1 | 1 | Phenotypic Suppression |
HOF1 | YMR032W | F-BAR protein that regulates actin cytoskeleton organization | genetic | 1 | 1 | 1 | Positive Genetic |
PKC1 | YBL105C | Protein serine/threonine kinase | genetic | 1 | 1 | 1 | Negative Genetic |
NBA1 | YOL070C | Protein involved in axial bud site selection | genetic | 1 | 1 | 1 | Negative Genetic |
MET14 | YKL001C | Adenylylsulfate kinase | genetic | 1 | 1 | 1 | Negative Genetic |
BRE5 | YNR051C | Ubiquitin protease cofactor | genetic | 1 | 1 | 1 | Negative Genetic |
RPL20B | YOR312C | Ribosomal 60S subunit protein L20B | genetic | 1 | 1 | 1 | Negative Genetic |
PUP1 | YOR157C | Beta 2 subunit of the 20S proteasome | genetic | 1 | 1 | 1 | Negative Genetic |
RSM19 | YNR037C | Mitochondrial ribosomal protein of the small subunit | genetic | 1 | 1 | 1 | Negative Genetic |
OST4 | YDL232W | Subunit of the oligosaccharyltransferase complex of the ER lumen | genetic | 1 | 1 | 1 | Negative Genetic |
MPT5 | YGL178W | mRNA-binding protein of the PUF family | physical | 1 | 1 | 1 | Affinity Capture-RNA |
CSG2 | YBR036C | Endoplasmic reticulum membrane protein | genetic | 1 | 1 | 1 | Positive Genetic |
RBL2 | YOR265W | Protein involved in microtubule morphogenesis | genetic | 1 | 1 | 1 | Negative Genetic |
SMI1 | YGR229C | Protein involved in the regulation of cell wall synthesis | genetic | 1 | 1 | 1 | Positive Genetic |
MRF1 | YGL143C | Mitochondrial translation release factor | genetic | 1 | 1 | 1 | Negative Genetic |
SNM1 | YDR478W | Ribonuclease MRP complex subunit | genetic | 1 | 1 | 1 | Negative Genetic |
FAT1 | YBR041W | Very long chain fatty acyl-CoA synthetase and fatty acid transporter | physical | 1 | 1 | 1 | Co-fractionation |
HRQ1 | YDR291W | 3'-5' DNA helicase of the conserved RecQ family | genetic | 1 | 1 | 1 | Negative Genetic |
KCS1 | YDR017C | Inositol hexakisphosphate and inositol heptakisphosphate kinase | genetic | 1 | 1 | 1 | Positive Genetic |
MRPL22 | YNL177C | Mitochondrial ribosomal protein of the large subunit | genetic | 1 | 1 | 1 | Negative Genetic |
JID1 | YPR061C | Probable Hsp40p co-chaperone | genetic | 1 | 1 | 1 | Negative Genetic |
DGA1 | YOR245C | Diacylglycerol acyltransferase | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
COQ8 | YGL119W | ATPase required for ubiquinone biosynthesis and respiratory growth | genetic | 1 | 1 | 1 | Negative Genetic |
EOS1 | YNL080C | Protein involved in N-glycosylation | genetic | 1 | 1 | 1 | Negative Genetic |
COX10 | YPL172C | Heme A:farnesyltransferase | genetic | 1 | 1 | 1 | Negative Genetic |
CYT1 | YOR065W | Cytochrome c1 | genetic | 1 | 1 | 1 | Negative Genetic |
OM14 | YBR230C | Mitochondrial outer membrane receptor for cytosolic ribosomes | physical | 1 | 1 | 1 | PCA |
AST2 | YER101C | Lipid raft associated protein | genetic | 1 | 1 | 1 | Negative Genetic |
ERG9 | YHR190W | Farnesyl-diphosphate farnesyl transferase (squalene synthase) | genetic | 1 | 1 | 1 | Negative Genetic |
YSC84 | YHR016C | Actin-binding protein | physical | 1 | 1 | 1 | Two-hybrid |
TGL3 | YMR313C | Bifunctional triacylglycerol lipase and LPE acyltransferase | physical | 1 | 1 | 1 | Affinity Capture-MS |
VAM6 | YDL077C | Guanine nucleotide exchange factor for the GTPase Gtr1p | physical | 1 | 1 | 1 | Affinity Capture-MS |
TOP1 | YOL006C | Topoisomerase I | genetic | 1 | 1 | 1 | Synthetic Growth Defect |
TSC13 | YDL015C | Enoyl reductase | genetic | 1 | 1 | 1 | Negative Genetic |
URB2 | YJR041C | Protein required for normal metabolism of the rRNA primary transcript | genetic | 1 | 1 | 1 | Negative Genetic |
VPS64 | YDR200C | Protein required for cytoplasm to vacuole targeting of proteins | genetic | 1 | 1 | 1 | Negative Genetic |
YJL070C | YJL070C | Putative metallo-dependent hydrolase superfamily protein | genetic | 1 | 1 | 1 | Negative Genetic |
TOK1 | YJL093C | Outward-rectifier potassium channel of the plasma membrane | genetic | 1 | 1 | 1 | Negative Genetic |
TOR1 | YJR066W | PIK-related protein kinase and rapamycin target | genetic | 1 | 1 | 1 | Phenotypic Enhancement |
TSR3 | YOR006C | Protein required for 20S pre-rRNA processing | genetic | 1 | 1 | 1 | Negative Genetic |
VPS5 | YOR069W | Nexin-1 homolog | genetic | 1 | 1 | 1 | Negative Genetic |
VPS30 | YPL120W | Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II | genetic | 1 | 1 | 1 | Negative Genetic |
VPS4 | YPR173C | AAA-ATPase involved in multivesicular body (MVB) protein sorting | genetic | 1 | 1 | 1 | Phenotypic Suppression |
ALG8 | YOR067C | Glucosyl transferase | genetic | 1 | 1 | 1 | Negative Genetic |
PGA3 | YML125C | Putative cytochrome b5 reductase, localized to the plasma membrane | genetic | 1 | 1 | 1 | Negative Genetic |
NCE101 | YJL205C | Protein of unknown function | genetic | 1 | 1 | 1 | Negative Genetic |
MRX11 | YPL041C | Protein that associates with mitochondrial ribosome | genetic | 1 | 1 | 1 | Negative Genetic |
SRF1 | YDL133W | Regulator of phospholipase D (Spo14p) | genetic | 1 | 1 | 1 | Negative Genetic |