OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
NCE102 |
YPR149W |
Protein of unknown function |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CHO2 |
YGR157W |
Phosphatidylethanolamine methyltransferase (PEMT) |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
2 |
2 |
Synthetic Haploinsufficiency, Synthetic Haploinsufficiency, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
3 |
2 |
2 |
Negative Genetic, Negative Genetic, Positive Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
PCT1 |
YGR202C |
Cholinephosphate cytidylyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ELO2 |
YCR034W |
Fatty acid elongase, involved in sphingolipid biosynthesis |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
OST5 |
YGL226C-A |
Zeta subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
ERV14 |
YGL054C |
COPII-coated vesicle protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEY1 |
YOR165W |
Dynamin-like GTPase that mediates homotypic ER fusion |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SVP26 |
YHR181W |
ER exit adaptor for Golgi mannosyltransferases |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWH1 |
YAR042W |
Protein similar to mammalian oxysterol-binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TIP1 |
YBR067C |
Major cell wall mannoprotein with possible lipase activity |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YHR045W |
YHR045W |
Putative protein of unknown function |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YNL190W |
YNL190W |
Hydrophilin essential in desiccation-rehydration process |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Lethality |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
ERG11 |
YHR007C |
Lanosterol 14-alpha-demethylase |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ASI3 |
YNL008C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EMC2 |
YJR088C |
Member of conserved ER transmembrane complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
THR4 |
YCR053W |
Threonine synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YCK1 |
YHR135C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
physical |
2 |
2 |
1 |
Two-hybrid, Affinity Capture-MS |
GEA2 |
YEL022W |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
INO4 |
YOL108C |
Transcription factor involved in phospholipid synthesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FAR8 |
YMR029C |
Protein involved in recovery from arrest in response to pheromone |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CAF4 |
YKR036C |
WD40 repeat-containing protein associated with the CCR4-NOT complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CUE5 |
YOR042W |
Ubiquitin-binding protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ELO3 |
YLR372W |
Elongase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FMO1 |
YHR176W |
Flavin-containing monooxygenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
GAS5 |
YOL030W |
1,3-beta-glucanosyltransferase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
EUG1 |
YDR518W |
Protein disulfide isomerase of the endoplasmic reticulum lumen |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
INP54 |
YOL065C |
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PEX34 |
YCL056C |
Protein that regulates peroxisome populations |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ATX2 |
YOR079C |
Golgi membrane protein involved in manganese homeostasis |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PER1 |
YCR044C |
Protein of the endoplasmic reticulum |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RTN1 |
YDR233C |
Reticulon protein |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SBH2 |
YER019C-A |
Ssh1p-Sss1p-Sbh2p complex component |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
UBX3 |
YDL091C |
Clathrin-coated vesicle component, regulator of endocytosis |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
TVS1 |
YCR061W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SAY1 |
YGR263C |
Sterol deacetylase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YGR266W |
YGR266W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YJR015W |
YJR015W |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YPS7 |
YDR349C |
Putative GPI-anchored aspartic protease |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RDL1 |
YOR285W |
Thiosulfate sulfurtransferase |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YMR253C |
YMR253C |
Putative protein of unknown function |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
GCR1 |
YPL075W |
Transcriptional activator of genes involved in glycolysis |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CST6 |
YIL036W |
Basic leucine zipper (bZIP) transcription factor from ATF/CREB family |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKA2 |
YOR061W |
Alpha' catalytic subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAS1 |
YMR290C |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPI1 |
YHR085W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC42 |
YLR229C |
Small rho-like GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
MFT1 |
YML062C |
Subunit of the THO complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUT1 |
YGL151W |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG26 |
YGL001C |
C-3 sterol dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSC82 |
YMR186W |
Cytoplasmic chaperone of the Hsp90 family |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CMD1 |
YBR109C |
Calmodulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIS1 |
YBR084W |
Mitochondrial C1-tetrahydrofolate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HSP82 |
YPL240C |
Hsp90 chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPT2 |
YKR067W |
Glycerol-3-phosphate/dihydroxyacetone phosphate sn-1 acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
BSP1 |
YPR171W |
Adapter that links synaptojanins to the cortical actin cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
genetic |
1 |
1 |
1 |
Negative Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPP1 |
YIL053W |
Constitutively expressed DL-glycerol-3-phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV10 |
YIL097W |
Subunit of GID complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EGD1 |
YPL037C |
Subunit beta1 of the nascent polypeptide-associated complex (NAC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMF1 |
YOR378W |
Low affinity NH4+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSP104 |
YLL026W |
Disaggregase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
genetic |
1 |
1 |
1 |
Negative Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
FUS3 |
YBL016W |
Mitogen-activated serine/threonine protein kinase involved in mating |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP53 |
YMR153W |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Two-hybrid |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
PEX29 |
YDR479C |
ER-resident protein involved in peroxisomal biogenesis |
physical |
1 |
1 |
1 |
Two-hybrid |
DSL1 |
YNL258C |
Peripheral membrane protein needed for Golgi-to-ER retrograde traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIT2 |
YCR005C |
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM18 |
YHR198C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBF1 |
YJR060W |
Basic helix-loop-helix (bHLH) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALF1 |
YNL148C |
Alpha-tubulin folding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAL80 |
YML051W |
Transcriptional regulator involved in the repression of GAL genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARG80 |
YMR042W |
Transcription factor involved in regulating arginine-responsive genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Negative Genetic |
MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTT1 |
YIR038C |
ER associated glutathione S-transferase |
physical |
1 |
1 |
1 |
Two-hybrid |
HBT1 |
YDL223C |
Shmoo tip protein, substrate of Hub1p ubiquitin-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIP1 |
YBL063W |
Kinesin-related motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC6 |
YLL014W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUE1 |
YMR264W |
Ubiquitin-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAT1 |
YBR041W |
Very long chain fatty acyl-CoA synthetase and fatty acid transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
BPH1 |
YCR032W |
Protein homologous to Chediak-Higashi syndrome and Beige proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA4 |
YLR218C |
Twin Cx(9)C protein involved in cytochrome c oxidase organization |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP5 |
YOR196C |
Protein involved in biosynthesis of the coenzyme lipoic acid |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPT1 |
YOR209C |
Nicotinate phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG21 |
YPL100W |
Phosphoinositide binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OSH7 |
YHR001W |
Oxysterol-binding phosphatidylserine transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC4 |
YGL231C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NCR1 |
YPL006W |
Vacuolar membrane protein involved with Npc2p in sterol trafficking |
genetic |
1 |
1 |
1 |
Negative Genetic |
CWH43 |
YCR017C |
GPI lipid remodelase |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASI1 |
YMR119W |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASI2 |
YNL159C |
Subunit of the inner nuclear membrane Asi ubiquitin ligase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYC2 |
YOR037W |
Mitochondrial peripheral inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GOT1 |
YMR292W |
Homodimeric protein that is packaged into COPII vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
COS1 |
YNL336W |
Endosomal protein involved in turnover of plasma membrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI14 |
YJR013W |
Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD16 |
YEL029C |
Putative pyridoxal kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL32 |
YBR299W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLF1 |
YDR515W |
RNA binding protein that associates with polysomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SRO9 |
YCL037C |
Cytoplasmic RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPC82 |
YPR190C |
RNA polymerase III subunit C82 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND2 |
YLR065C |
Protein involved in SRP-independent targeting of substrates to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SND3 |
YBR106W |
Involved in SRP-independent protein targeting to the ER |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLG1 |
YOR008C |
Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCO2 |
YBR024W |
Protein anchored to mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPS2 |
YDR074W |
Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOP4 |
YJL192C |
ER-membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO86 |
YJL117W |
Endoplasmic reticulum (ER) resident protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL063C |
YKL063C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBC7 |
YMR022W |
Ubiquitin conjugating enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
1 |
1 |
1 |
Negative Genetic |
ULS1 |
YOR191W |
Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSP2 |
YOR242C |
Sporulation specific protein that localizes to the spore wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF11 |
YPL047W |
Integral subunit of SAGA histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR2 |
YPR191W |
Subunit 2 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAT1 |
YAR035W |
Outer mitochondrial carnitine acetyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWP82 |
YFL049W |
Member of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF73 |
YGL066W |
Subunit of DUBm module of SAGA and SLIK |
genetic |
1 |
1 |
1 |
Negative Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF4631 |
YGR162W |
Translation initiation factor eIF4G and scaffold protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCI37 |
YIL077C |
Protein that associates with the large mitoribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGL3 |
YMR313C |
Bifunctional triacylglycerol lipase and LPE acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE5 |
YMR314W |
Alpha 6 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD50 |
YNL250W |
Subunit of MRX complex with Mre11p and Xrs2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
1 |
1 |
1 |
Positive Genetic |
YCL001W-A |
YCL001W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TCM62 |
YBR044C |
Protein involved in assembly of the succinate dehydrogenase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJR011C |
YJR011C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFB3 |
YHR098C |
Component of the Sec23p-Sfb3p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
SFB2 |
YNL049C |
Component of the Sec23p-Sfb2p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIB5 |
YBR256C |
Riboflavin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL28 |
YGL103W |
Ribosomal 60S subunit protein L28 |
genetic |
1 |
1 |
1 |
Negative Genetic |
URB2 |
YJR041C |
Protein required for normal metabolism of the rRNA primary transcript |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOF1 |
YLL011W |
Protein required for biogenesis of 40S (small) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAD3 |
YLR316C |
Subunit of tRNA-specific adenosine-34 deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP3 |
YNL282W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF6 |
YPR016C |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMX3 |
YPR182W |
Core Sm protein Sm F |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL081W |
YGL081W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF4 |
YKL081W |
Gamma subunit of translational elongation factor eEF1B |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO80 |
YOL001W |
Cyclin |
genetic |
1 |
1 |
1 |
Negative Genetic |
REI1 |
YBR267W |
Cytoplasmic pre-60S factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP2 |
YER090W |
Anthranilate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR127W |
YHR127W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL077W-B |
YJL077W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGL1 |
YKL140W |
Steryl ester hydrolase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TMC1 |
YOR052C |
AN1-type zinc finger protein, effector of proteotoxic stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
UAF30 |
YOR295W |
Subunit of UAF (upstream activation factor) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR202W |
YPR202W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS19A |
YOL121C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL4 |
YCR014C |
DNA polymerase IV |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS11A |
YDR025W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |