USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
physical |
8 |
3 |
7 |
Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
physical |
5 |
2 |
5 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
RER1 |
YCL001W |
Protein involved in retention of membrane proteins |
genetic |
4 |
2 |
3 |
Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
physical |
3 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
PRC1 |
YMR297W |
Vacuolar carboxypeptidase Y (proteinase C, CPY) |
physical |
3 |
1 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
USA1 |
YML029W |
Scaffold subunit of the Hrd1p ubiquitin ligase |
genetic |
3 |
2 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Enhancement |
UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
3 |
2 |
2 |
Positive Genetic, Positive Genetic, Negative Genetic |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
3 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic |
HRD1 |
YOL013C |
Ubiquitin-protein ligase involved in ER-associated degradation (ERAD) |
genetic |
3 |
1 |
2 |
Phenotypic Suppression, Phenotypic Suppression, Phenotypic Suppression |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
PRX1 |
YBL064C |
Mitochondrial peroxiredoxin with thioredoxin peroxidase activity |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MHP1 |
YJL042W |
Microtubule-associated protein involved in microtubule organization |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HOM6 |
YJR139C |
Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
IRS4 |
YKR019C |
EH domain-containing protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
ERG6 |
YML008C |
Delta(24)-sterol C-methyltransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MSS1 |
YMR023C |
Mitochondrial protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HIR2 |
YOR038C |
Subunit of HIR nucleosome assembly complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
WHI2 |
YOR043W |
Negative regulator of TORC1 in response to limiting leucine |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
DIA2 |
YOR080W |
Origin-binding F-box protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
YOP1 |
YPR028W |
Reticulon-interacting protein |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
NPL4 |
YBR170C |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
UBX2 |
YML013W |
Bridging factor involved in ER-associated protein degradation (ERAD) |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS |
IRE1 |
YHR079C |
Serine-threonine kinase and endoribonuclease |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG18 |
YFR021W |
Phosphoinositide binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD13 |
YGL174W |
Subunit of the RES complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG11 |
YPR049C |
Adapter protein for pexophagy and the Cvt targeting pathway |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CAJ1 |
YER048C |
Nuclear type II J heat shock protein of the E. coli dnaJ family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DIN7 |
YDR263C |
Mitochondrial nuclease functioning in DNA repair and replication |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MMS2 |
YGL087C |
Ubiquitin-conjugating enzyme variant |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MVB12 |
YGR206W |
ESCRT-I subunit required to stabilize ESCRT-I core complex oligomers |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SOD2 |
YHR008C |
Mitochondrial manganese superoxide dismutase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS27B |
YHR021C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PPE1 |
YHR075C |
Protein with carboxyl methyl esterase activity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RRD1 |
YIL153W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YAK1 |
YJL141C |
Serine-threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAM17 |
YKR065C |
Constituent of the TIM23 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT7 |
YML001W |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PFK2 |
YMR205C |
Beta subunit of heterooctameric phosphofructokinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWS2 |
YNL081C |
Putative mitochondrial ribosomal protein of the small subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ITR2 |
YOL103W |
Myo-inositol transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDH5 |
YOL071W |
Protein required for flavinylation of Sdh1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPE2 |
YOL052C |
S-adenosylmethionine decarboxylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GSH2 |
YOL049W |
Glutathione synthetase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTC5 |
YOR090C |
Mitochondrial type 2C protein phosphatase (PP2C) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
INP53 |
YOR109W |
Polyphosphatidylinositol phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HUA2 |
YOR284W |
Cytoplasmic protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SNU66 |
YOR308C |
Component of the U4/U6.U5 snRNP complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ISU1 |
YPL135W |
Conserved protein of the mitochondrial matrix |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MFM1 |
YPL060W |
Mitochondrial inner membrane magnesium transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DBR1 |
YKL149C |
RNA lariat debranching enzyme |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
HRD3 |
YLR207W |
ER membrane protein that plays a central role in ERAD |
genetic |
2 |
1 |
1 |
Phenotypic Suppression, Phenotypic Suppression |
DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PGA3 |
YML125C |
Putative cytochrome b5 reductase, localized to the plasma membrane |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RGP1 |
YDR137W |
Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RPP2B |
YDR382W |
Ribosomal protein P2 beta |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VAM3 |
YOR106W |
Syntaxin-like vacuolar t-SNARE |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
LEM3 |
YNL323W |
Membrane protein of the plasma membrane and ER |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
FKH1 |
YIL131C |
Forkhead family transcription factor |
genetic |
2 |
1 |
1 |
Phenotypic Enhancement, Phenotypic Enhancement |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBP3 |
YGL078C |
RNA-Dependent ATPase, member of DExD/H-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
AEP2 |
YMR282C |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APP1 |
YNL094W |
Phosphatidate phosphatase, converts phosphatidate to diacylglycerol |
genetic |
1 |
1 |
1 |
Negative Genetic |
COF1 |
YLL050C |
Cofilin, involved in pH-dependent actin filament depolarization |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAT5 |
YOR125C |
Protein required for ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
APE2 |
YKL157W |
Aminopeptidase yscII |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIR1 |
YJR089W |
Subunit of chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSG2 |
YBR036C |
Endoplasmic reticulum membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB4 |
YGR277C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ6 |
YGR255C |
Flavin-dependent monooxygenase involved in ubiquinone biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOS9 |
YDR057W |
ER quality-control lectin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YOS9 |
YDR057W |
ER quality-control lectin |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DFM1 |
YDR411C |
Endoplasmic reticulum (ER) localized protein |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PEP4 |
YPL154C |
Vacuolar aspartyl protease (proteinase A) |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM8 |
YGL045W |
Protein involved in proteolytic activation of Rim101p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCP1 |
YGR101W |
Mitochondrial serine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAL12 |
YGR292W |
Maltase (alpha-D-glucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHR1 |
YIL056W |
Transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCK2 |
YLR248W |
Protein kinase involved in response to oxidative and osmotic stress |
genetic |
1 |
1 |
1 |
Negative Genetic |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAM37 |
YMR060C |
Component of the Sorting and Assembly Machinery (SAM) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSO2 |
YMR183C |
Plasma membrane t-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERV41 |
YML067C |
Protein localized to COPII-coated vesicles |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
HAC1 |
YFL031W |
Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP43 |
YCR035C |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG2 |
YGL252C |
Sensor of mitochondrial dysfunction |
genetic |
1 |
1 |
1 |
Positive Genetic |
GTR2 |
YGR163W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP4 |
YKL109W |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MEH1 |
YKR007W |
Subunit of the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTG1 |
YOL067C |
Transcription factor (bHLH) involved in interorganelle communication |
genetic |
1 |
1 |
1 |
Positive Genetic |
RTC1 |
YOL138C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HPF1 |
YOL155C |
Haze-protective mannoprotein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGT2 |
YOR007C |
Glutamine-rich cytoplasmic cochaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
EEB1 |
YPL095C |
Acyl-coenzymeA:ethanol O-acyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RMD9 |
YGL107C |
Mitochondrial protein that controls mitochondrial gene expression |
genetic |
1 |
1 |
1 |
Positive Genetic |
ROF1 |
YHR177W |
Putative transcription factor containing a WOPR domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED6 |
YHR058C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUA7 |
YPR086W |
Transcription factor TFIIB |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR1 |
YCL044C |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMG2 |
YCR071C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPT1 |
YDR072C |
Inositolphosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET2 |
YER083C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER084W |
YER084W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS2 |
YER120W |
Integral ER membrane protein, regulates phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR018C |
YGR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKN1 |
YGR143W |
Protein involved in sphingolipid biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTD2 |
YHR067W |
Mitochondrial 3-hydroxyacyl-thioester dehydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
XBP1 |
YIL101C |
Transcriptional repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP21 |
YIL154C |
Transcriptional activator involved in maintenance of ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH9 |
YJL045W |
Minor succinate dehydrogenase isozyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS24 |
YKL041W |
One of four subunits of the ESCRT-III complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS27A |
YKL156W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE1 |
YKL184W |
Ornithine decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMM1 |
YLL006W |
ER integral membrane protein, ERMES complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSR1 |
YLL010C |
Plasma membrane-associated protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS3 |
YLR094C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPS1 |
YLR193C |
Phosphatidic acid transfer protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI7 |
YLR237W |
Plasma membrane transporter responsible for the uptake of thiamine |
genetic |
1 |
1 |
1 |
Negative Genetic |
EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUS3 |
YLR401C |
Dihydrouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD52 |
YML032C |
Protein involved in homologous recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCB3 |
YML072C |
Cortical ER protein involved in ER-plasma membrane tethering |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGR3 |
YMR115W |
Subunit of the mitochondrial (mt) i-AAA protease supercomplex |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR11 |
YNL127W |
Protein involved in recovery from cell cycle arrest |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
STD1 |
YOR047C |
Protein involved in control of glucose-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
WHI5 |
YOR083W |
Repressor of G1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENV9 |
YOR246C |
Conserved oxidoreductase involved in lipid droplet morphology |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMI1 |
YPL024W |
Subunit of the RecQ (Sgs1p) - Topo III (Top3p) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELP3 |
YPL086C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS62 |
YGR141W |
Vacuolar protein sorting (VPS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPI8 |
YJL133C-A |
Putative mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGM101 |
YJR144W |
Protein with a role in mitochondrial DNA recombinational repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG24 |
YNL280C |
C-14 sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARO7 |
YPR060C |
Chorismate mutase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR6 |
YGL247W |
Essential nuclear envelope integral membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
AIM32 |
YML050W |
2Fe-2S mitochondrial protein involved in redox quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRD1 |
YDL142C |
Cardiolipin synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADY2 |
YCR010C |
Acetate transporter required for normal sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIF1 |
YNR074C |
Mitochondrial cell death effector |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |