Standard name Systematic name Name description Description
YOP1 YPR028W Reticulon-interacting protein Reticulon-interacting protein; ER integral membrane protein involved in the generation of tubular ER morphology; promotes membrane curvature; forms tubules in vitro; regulates the ER asymmetry-induced inheritance block during ER stress; role in ER-derived peroxisomal biogenesis; interacts with Yip1p to mediate membrane traffic and with Sey1p to maintain ER morphology; facilitates lipid exchange between the ER and mitochondria; forms ER foci upon DNA replication stress
Visualize the interactome of YOP1
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cell Periphery 0.191 0.298 0.199
Cort. Patches 0.108 0.239 0.352
Cytoplasm 0.181 0.112 0.065
ER 0.621 0.574 0.578
Golgi 0.076 NaN 0.158
Bud NaN NaN 0.067

GFP localization & abundance

GFP localization GFP abundance
ER 1760

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
YOP1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
SEY1 YOR165W Dynamin-like GTPase that mediates homotypic ER fusion genetic 7 2 6 Negative Genetic, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Phenotypic Enhancement, Negative Genetic, Negative Genetic
PEX30 YLR324W ER-resident protein involved in peroxisomal biogenesis physical 5 3 2 Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
PEX29 YDR479C ER-resident protein involved in peroxisomal biogenesis physical 4 2 1 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
RTN1 YDR233C Reticulon protein physical 4 2 1 Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
LNP1 YHR192W Lunapark family member involved in ER network formation genetic 3 2 3 Synthetic Growth Defect, Synthetic Growth Defect, Phenotypic Suppression
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 3 2 2 PCA, Affinity Capture-Western, PCA
DER1 YBR201W ER membrane protein that promotes export of misfolded polypeptides genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
YIP1 YGR172C Integral membrane protein physical 3 2 1 Affinity Capture-Western, Two-hybrid, Two-hybrid
FKH2 YNL068C Forkhead family transcription factor regulation 2 2 2 chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) physical 2 2 2 Affinity Capture-Western, Two-hybrid
RTN1 YDR233C Reticulon protein genetic 2 2 2 Synthetic Growth Defect, Phenotypic Enhancement
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit genetic 2 2 2 Negative Genetic, Synthetic Growth Defect
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
POM34 YLR018C Subunit of the transmembrane ring of the nuclear pore complex (NPC) physical 2 1 2 PCA, PCA
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 2 2 1 Phenotypic Enhancement, Phenotypic Suppression
YPR003C YPR003C Putative sulfate permease genetic 2 1 1 Negative Genetic, Negative Genetic
YPR063C YPR063C ER-localized protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
SST2 YLR452C GTPase-activating protein for Gpa1p genetic 2 1 1 Negative Genetic, Negative Genetic
SEY1 YOR165W Dynamin-like GTPase that mediates homotypic ER fusion physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YET2 YMR040W Protein of unknown function that may interact with ribosomes genetic 2 1 1 Negative Genetic, Negative Genetic
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
MSN2 YMR037C Stress-responsive transcriptional activator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ABF1 YKL112W DNA binding protein with possible chromatin-reorganizing activity regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ADA2 YDR448W Transcription coactivator regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PAB1 YER165W Poly(A) binding protein physical 1 1 1 Affinity Capture-MS
RPN11 YFR004W Metalloprotease subunit of 19S regulatory particle physical 1 1 1 Affinity Capture-MS
KAP95 YLR347C Karyopherin beta genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
NUP82 YJL061W Linker nucleoporin component of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
ATG14 YBR128C Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I physical 1 1 1 Affinity Capture-MS
CDC23 YHR166C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
MDM10 YAL010C Subunit of both the ERMES and the SAM complex genetic 1 1 1 Synthetic Growth Defect
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family physical 1 1 1 Affinity Capture-MS
NUP116 YMR047C FG-nucleoporin component of central core of the nuclear pore complex genetic 1 1 1 Synthetic Lethality
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
SCS2 YER120W Integral ER membrane protein, regulates phospholipid metabolism physical 1 1 1 Affinity Capture-MS
NUP120 YKL057C Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
NUP145 YGL092W Essential protein with distinct roles in two nuclear pore subcomplexes genetic 1 1 1 Synthetic Lethality
NUP85 YJR042W Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
AVT4 YNL101W Vacuolar transporter physical 1 1 1 PCA
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Synthetic Lethality
SPO7 YAL009W Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 1 1 1 Synthetic Lethality
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
ACO1 YLR304C Aconitase genetic 1 1 1 Negative Genetic
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
SEC4 YFL005W Rab family GTPase physical 1 1 1 Affinity Capture-Western
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
NDC1 YML031W Subunit of the transmembrane ring of the nuclear pore complex (NPC) genetic 1 1 1 Phenotypic Suppression
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) genetic 1 1 1 Synthetic Growth Defect
PPA2 YMR267W Mitochondrial inorganic pyrophosphatase genetic 1 1 1 Positive Genetic
NUR1 YDL089W Protein involved in regulation of mitotic exit physical 1 1 1 Two-hybrid
YIF1 YNL263C Integral membrane protein physical 1 1 1 Two-hybrid
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
IES3 YLR052W Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
MDM12 YOL009C Mitochondrial outer membrane protein, ERMES complex subunit genetic 1 1 1 Synthetic Growth Defect
SIP5 YMR140W Protein of unknown function genetic 1 1 1 Phenotypic Suppression
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs genetic 1 1 1 Phenotypic Suppression
SSA1 YAL005C ATPase involved in protein folding and NLS-directed nuclear transport physical 1 1 1 Affinity Capture-MS
TUB4 YLR212C Gamma-tubulin genetic 1 1 1 Synthetic Growth Defect
YIP1 YGR172C Integral membrane protein genetic 1 1 1 Dosage Rescue
ATG2 YNL242W Peripheral membrane protein required for autophagic vesicle formation physical 1 1 1 Affinity Capture-MS
BBP1 YPL255W Protein required for the spindle pole body (SPB) duplication genetic 1 1 1 Phenotypic Suppression
SSA2 YLL024C HSP70 family ATP-binding protein physical 1 1 1 Affinity Capture-MS
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
YPT52 YKR014C Endosomal Rab family GTPase physical 1 1 1 Affinity Capture-Western
YPT6 YLR262C Rab family GTPase physical 1 1 1 Affinity Capture-Western
YPT7 YML001W Rab family GTPase physical 1 1 1 Affinity Capture-Western
YOP1 YPR028W Reticulon-interacting protein physical 1 1 1 Co-purification
YPL264C YPL264C Endoplasmic reticulum protein of unknown function physical 1 1 1 PCA
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Positive Genetic
ERG25 YGR060W C-4 methyl sterol oxidase physical 1 1 1 PCA
BSD2 YBR290W Heavy metal ion homeostasis protein physical 1 1 1 PCA
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Synthetic Lethality
BET4 YJL031C Alpha subunit of Type II geranylgeranyltransferase genetic 1 1 1 Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
DPM1 YPR183W Dolichol phosphate mannose (Dol-P-Man) synthase of ER membrane physical 1 1 1 Affinity Capture-MS
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex physical 1 1 1 PCA
POM152 YMR129W Glycoprotein subunit of transmembrane ring of nuclear pore complex genetic 1 1 1 Synthetic Lethality
AGP2 YBR132C Plasma membrane regulator of polyamine and carnitine transport genetic 1 1 1 Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI physical 1 1 1 PCA
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
SSH1 YBR283C Subunit of the Ssh1 translocon complex physical 1 1 1 PCA
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase physical 1 1 1 PCA
POM33 YLL023C Transmembrane nucleoporin physical 1 1 1 PCA
PET130 YJL023C Protein of unknown function genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase physical 1 1 1 PCA
GAS3 YMR215W Putative 1,3-beta-glucanosyltransferase physical 1 1 1 PCA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
NSG1 YHR133C Protein involved in regulation of sterol biosynthesis physical 1 1 1 PCA
PEX31 YGR004W Peroxisomal integral membrane protein physical 1 1 1 Two-hybrid
ASI2 YNL159C Subunit of the inner nuclear membrane Asi ubiquitin ligase complex genetic 1 1 1 Negative Genetic
MPS3 YJL019W Nuclear envelope protein physical 1 1 1 Affinity Capture-MS
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
COS8 YHL048W Endosomal protein involved in turnover of plasma membrane proteins physical 1 1 1 PCA
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
ELO1 YJL196C Elongase I, medium-chain acyl elongase physical 1 1 1 PCA
SAM50 YNL026W Component of the Sorting and Assembly Machinery (SAM) complex physical 1 1 1 Affinity Capture-MS
COX20 YDR231C Mitochondrial inner membrane protein physical 1 1 1 Affinity Capture-MS
MAL11 YGR289C High-affinity maltose transporter (alpha-glucoside transporter) physical 1 1 1 PCA
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
MCD4 YKL165C Protein involved in GPI anchor synthesis physical 1 1 1 PCA
LNP1 YHR192W Lunapark family member involved in ER network formation physical 1 1 1 Affinity Capture-Western
ALG11 YNL048W Alpha-1,2-mannosyltransferase physical 1 1 1 PCA
YHR140W YHR140W Endoplasmic reticulum protein physical 1 1 1 PCA
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex physical 1 1 1 PCA
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Dosage Growth Defect
VPS73 YGL104C Mitochondrial protein physical 1 1 1 PCA
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease physical 1 1 1 PCA
YHL042W YHL042W Endoplasmic reticulum protein physical 1 1 1 PCA
YET3 YDL072C Protein of unknown function physical 1 1 1 Affinity Capture-MS
YOL036W YOL036W Protein of unknown function genetic 1 1 1 Negative Genetic
YML020W YML020W Putative protein of unknown function genetic 1 1 1 Negative Genetic