NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
16 |
5 |
10 |
Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
genetic |
6 |
4 |
5 |
Synthetic Growth Defect, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic |
POM34 |
YLR018C |
Subunit of the transmembrane ring of the nuclear pore complex (NPC) |
genetic |
4 |
2 |
4 |
Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality |
ECM1 |
YAL059W |
Pre-ribosomal factor involved in 60S ribosomal protein subunit export |
genetic |
4 |
3 |
3 |
Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Negative Genetic |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
3 |
2 |
3 |
Affinity Capture-RNA, Affinity Capture-MS, Affinity Capture-MS |
NSP1 |
YJL041W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
NUP82 |
YJL061W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
3 |
1 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
NUP42 |
YDR192C |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Two-hybrid |
NUP145 |
YGL092W |
Essential protein with distinct roles in two nuclear pore subcomplexes |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPN6 |
YDL097C |
Essential, non-ATPase regulatory subunit of the 26S proteasome lid |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
LCB2 |
YDR062W |
Component of serine palmitoyltransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPN11 |
YFR004W |
Metalloprotease subunit of 19S regulatory particle |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPN12 |
YFR052W |
Subunit of the 19S regulatory particle of the 26S proteasome lid |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPT6 |
YGL048C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPT1 |
YKL145W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
MCM5 |
YLR274W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
PRE2 |
YPR103W |
Beta 5 subunit of the 20S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
NUT2 |
YPR168W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CDC53 |
YDL132W |
Cullin |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Rescue |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NUP42 |
YDR192C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP84 |
YDL116W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SHE1 |
YBL031W |
Mitotic spindle protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLX9 |
YGR081C |
Protein required for pre-rRNA processing |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ICE2 |
YIL090W |
Integral ER membrane protein with type-III transmembrane domains |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STE24 |
YJR117W |
Highly conserved zinc metalloprotease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOF2 |
YKR010C |
Protein required for rDNA silencing and mitotic rDNA condensation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
POM33 |
YLL023C |
Transmembrane nucleoporin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP2 |
YLR335W |
Nucleoporin involved in nucleocytoplasmic transport |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBX4 |
YMR067C |
UBX domain-containing protein that interacts with Cdc48p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SIN3 |
YOL004W |
Component of both the Rpd3S and Rpd3L histone deacetylase complexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPL21B |
YPL079W |
Ribosomal 60S subunit protein L21B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CHL1 |
YPL008W |
Probable DNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ATG8 |
YBL078C |
Ub-like protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EMC6 |
YLL014W |
Member of conserved ER transmembrane complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DCV1 |
YFR012W |
Protein of unknown function |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
2 |
2 |
1 |
Synthetic Growth Defect, Dosage Rescue |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
RFX1 |
YLR176C |
Major transcriptional repressor of DNA-damage-regulated genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CLF1 |
YLR117C |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP7 |
YPR034W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ARX1 |
YDR101C |
Nuclear export factor for the ribosomal pre-60S subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ADE4 |
YMR300C |
Phosphoribosylpyrophosphate amidotransferase (PRPPAT) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASF1 |
YJL115W |
Nucleosome assembly factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD20 |
YLR074C |
C2H2-type zinc finger protein required for ribosome assembly |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC24 |
YAL041W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC16 |
YKL022C |
Subunit of the anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPB2 |
YPR175W |
Second largest subunit of DNA polymerase II (DNA polymerase epsilon) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ERO1 |
YML130C |
Thiol oxidase required for oxidative protein folding in the ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRO1 |
YDR300C |
Gamma-glutamyl kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP116 |
YMR047C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP159 |
YIL115C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
REA1 |
YLR106C |
Huge dynein-related AAA-type ATPase (midasin) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC3 |
YDR159W |
mRNA export factor |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP157 |
YER105C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
POM152 |
YMR129W |
Glycoprotein subunit of transmembrane ring of nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NIC96 |
YFR002W |
Linker nucleoporin component of the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SPT7 |
YBR081C |
Subunit of the SAGA transcriptional regulatory complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TAF6 |
YGL112C |
Subunit (60 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP1 |
YNL189W |
Karyopherin alpha homolog |
physical |
1 |
1 |
1 |
Two-hybrid |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
MLP1 |
YKR095W |
Myosin-like protein associated with the nuclear envelope |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
NMD3 |
YHR170W |
Protein involved in nuclear export of the large ribosomal subunit |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PUF3 |
YLL013C |
Protein of the mitochondrial outer surface |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GLE2 |
YER107C |
RNA export factor associated with the nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Reconstituted Complex |
NUP100 |
YKL068W |
FG-nucleoporin component of central core of the nuclear pore complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC61 |
YLR378C |
Conserved ER protein translocation channel |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
UBP15 |
YMR304W |
Ubiquitin-specific protease involved in protein deubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SNL1 |
YIL016W |
Ribosome-associated protein |
genetic |
1 |
1 |
1 |
Dosage Rescue |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RTN1 |
YDR233C |
Reticulon protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
YOP1 |
YPR028W |
Reticulon-interacting protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
XRN1 |
YGL173C |
Evolutionarily-conserved 5'-3' exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
MTR2 |
YKL186C |
mRNA transport regulator |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
PDC2 |
YDR081C |
Transcription factor for thiamine-regulated genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
ULP1 |
YPL020C |
Protease that specifically cleaves Smt3p protein conjugates |
genetic |
1 |
1 |
1 |
Positive Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ILM1 |
YJR118C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL14A |
YKL006W |
Ribosomal 60S subunit protein L14A |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA19 |
YKL056C |
Protein that associates with ribosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
RRP6 |
YOR001W |
Nuclear exosome exonuclease component |
genetic |
1 |
1 |
1 |
Positive Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCG1 |
YDR325W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE4 |
YFR050C |
Beta 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
STS1 |
YIR011C |
Protein required for localizing proteasomes to the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL31 |
YJR006W |
Subunit of DNA polymerase delta (polymerase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAH11 |
YJR046W |
DNA replication licensing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GSP1 |
YLR293C |
Ran GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM1 |
YMR043W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE10 |
YOR362C |
Alpha 7 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
HUR1 |
YGL168W |
Protein with a role in DNA repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEA4 |
YBL104C |
Subunit of SEACAT, a subcomplex of the SEA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC1 |
YDL006W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NNF2 |
YGR089W |
Protein that exhibits physical and genetic interactions with Rpb8p |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS62 |
YGR141W |
Vacuolar protein sorting (VPS) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PBP1 |
YGR178C |
Component of glucose deprivation induced stress granules |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR9 |
YGR183C |
Subunit 9 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT102 |
YGR275W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIA6 |
YIL006W |
Mitochondrial NAD+ transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
URM1 |
YIL008W |
Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs |
genetic |
1 |
1 |
1 |
Negative Genetic |
POT1 |
YIL160C |
3-ketoacyl-CoA thiolase with broad chain length specificity |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET28 |
YIR017C |
bZIP transcriptional activator in the Cbf1p-Met4p-Met28p complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM35 |
YKL053C-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OAR1 |
YKL055C |
Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
LIP2 |
YLR239C |
Lipoyl ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRC1 |
YML034W |
Inner nuclear membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCT1 |
YOR221C |
Predicted malonyl-CoA:ACP transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6A |
YPL090C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VIK1 |
YPL253C |
Protein that forms a kinesin-14 heterodimeric motor with Kar3p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SFH1 |
YLR321C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SCC2 |
YDR180W |
Subunit of cohesin loading factor (Scc2p-Scc4p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUB2 |
YDL084W |
Component of the TREX complex required for nuclear mRNA export |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPN1 |
YPR133C |
Protein involved in RNA polymerase II transcription |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPT15 |
YER148W |
TATA-binding protein (TBP) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF10 |
YDR167W |
Subunit (145 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF12 |
YDR145W |
Subunit (61/68 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TAF7 |
YMR227C |
TFIID subunit (67 kDa) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
TFB3 |
YDR460W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCM10 |
YIL150C |
Essential chromatin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCM2 |
YBL023C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
POL2 |
YNL262W |
Catalytic subunit of DNA polymerase (II) epsilon |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RFC5 |
YBR087W |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MAK11 |
YKL021C |
Protein involved in an early step of 60S ribosomal subunit biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SDO1 |
YLR022C |
Guanine nucleotide exchange factor (GEF) for Ria1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PUP1 |
YOR157C |
Beta 2 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC21 |
YNL287W |
Gamma subunit of coatomer |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC26 |
YDR238C |
Essential beta-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SLY1 |
YDR189W |
Hydrophilic protein involved in ER/Golgi vesicle trafficking |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
UFE1 |
YOR075W |
t-SNARE protein required for retrograde vesicular traffic |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAR2 |
YJL034W |
ATPase involved in protein import into the ER |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HTS1 |
YPR033C |
Cytoplasmic and mitochondrial histidine tRNA synthetase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KRE5 |
YOR336W |
Protein required for beta-1,6 glucan biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPG1 |
YBR079C |
eIF3a subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SUP45 |
YBR143C |
Polypeptide release factor (eRF1) in translation termination |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
URA6 |
YKL024C |
Uridylate kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MPS2 |
YGL075C |
Essential membrane protein localized at nuclear envelope and SPBs |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
GCN5 |
YGR252W |
Catalytic subunit of ADA and SAGA histone acetyltransferase complexes |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG12 |
YBR217W |
Ubiquitin-like modifier involved in autophagy and the Cvt pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASM4 |
YDL088C |
FG-nucleoporin component of central core of nuclear pore complex (NPC) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CSM3 |
YMR048W |
Replication fork associated factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC34 |
YDR054C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC11 |
YDL008W |
Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC21 |
YOR074C |
Thymidylate synthase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATG8 |
YBL078C |
Ub-like protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRN1 |
YBL097W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECO1 |
YFR027W |
Acetyltransferase required for sister chromatid cohesion |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BIK1 |
YCL029C |
Microtubule-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAL10 |
YBR019C |
UDP-glucose-4-epimerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EMC5 |
YIL027C |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLB3 |
YDL155W |
B-type cyclin involved in cell cycle progression |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG5 |
YMR015C |
C-22 sterol desaturase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASE1 |
YOR058C |
Mitotic spindle midzone-localized microtubule bundling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM22 |
YJL046W |
Lipoate-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEG1 |
YFL001W |
tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
1 |
1 |
1 |
Positive Genetic |
COX7 |
YMR256C |
Subunit VII of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ERG9 |
YHR190W |
Farnesyl-diphosphate farnesyl transferase (squalene synthase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC3 |
YKL207W |
Member of conserved ER transmembrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |