Standard name Systematic name Name description Description
GUP1 YGL084C Plasma membrane protein involved in remodeling GPI anchors Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; role in misfolded protein quality control; proposed to be involved in glycerol transport; homolog of the mammalian Hedgehog pathway modulator HHATL; GUP1 has a paralog, GUP2, that arose from the whole genome duplication
Visualize the interactome of GUP1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.173 0.306 0.164
ER 0.822 0.709 0.732
Cort. Patches NaN NaN 0.068
Endosome NaN NaN 0.050
Vac/Vac Memb NaN NaN 0.086

GFP localization & abundance

GFP localization GFP abundance
ER 672

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
GUP1 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1171 (glycerol transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
ERG6 YML008C Delta(24)-sterol C-methyltransferase genetic 10 1 7 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GAS1 YMR307W Beta-1,3-glucanosyltransferase required for cell wall assembly genetic 8 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 7 1 6 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 7 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ELO3 YLR372W Elongase genetic 7 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 7 1 5 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 6 2 5 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
BCK1 YJL095W MAPKKK acting in the protein kinase C signaling pathway genetic 6 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 6 2 4 Negative Genetic, Negative Genetic, Dosage Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
OST3 YOR085W Gamma subunit of the oligosaccharyltransferase complex of the ER lumen genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHS3 YBR023C Chitin synthase III genetic 5 2 5 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 5 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 5 3 4 Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Positive Genetic, Negative Genetic
ELM1 YKL048C Serine/threonine protein kinase genetic 5 2 4 Negative Genetic, Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CNE1 YAL058W Calnexin genetic 5 2 4 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic
BST1 YFL025C GPI inositol deacylase of the endoplasmic reticulum (ER) genetic 5 1 4 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ARV1 YLR242C Cortical ER protein genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT2 YAL023C Protein O-mannosyltransferase of the ER membrane genetic 5 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRS65 YGR166W Component of transport protein particle (TRAPP) complex II genetic 4 2 4 Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 4 3 3 Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 4 2 3 Negative Genetic, Negative Genetic, Negative Genetic, Positive Genetic
CWH43 YCR017C GPI lipid remodelase genetic 4 2 3 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CSF1 YLR087C Protein with structural similarity to lipid transport protein Vps13p genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ALG3 YBL082C Dolichol-P-Man dependent alpha(1-3) mannosyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT1 YDL095W Protein O-mannosyltransferase of the ER membrane genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMT4 YJR143C Protein O-mannosyltransferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RER1 YCL001W Protein involved in retention of membrane proteins genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
OST6 YML019W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ROT1 YMR200W Molecular chaperone involved in protein folding in ER genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PER1 YCR044C Protein of the endoplasmic reticulum genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHS7 YHR142W Protein of unknown function genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
ALG8 YOR067C Glucosyl transferase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 3 2 3 Synthetic Lethality, Negative Genetic, Negative Genetic
LCB5 YLR260W Minor sphingoid long-chain base kinase genetic 3 2 3 Negative Genetic, Positive Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ECM33 YBR078W GPI-anchored protein involved in efficient glucose uptake genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
NBP2 YDR162C Protein involved in the HOG (high osmolarity glycerol) pathway genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
MID2 YLR332W O-glycosylated plasma membrane protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
STE24 YJR117W Highly conserved zinc metalloprotease genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
ERG3 YLR056W C-5 sterol desaturase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 3 3 2 Synthetic Rescue, Positive Genetic, Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 3 2 2 Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic
CRG1 YHR209W S-AdoMet-dependent methyltransferase involved in lipid homeostasis genetic 3 2 2 Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality
CWH41 YGL027C Processing alpha glucosidase I genetic 3 2 2 Negative Genetic, Negative Genetic, Synthetic Growth Defect
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 3 2 2 Positive Genetic, Negative Genetic, Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
CNB1 YKL190W Calcineurin B genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ELO2 YCR034W Fatty acid elongase, involved in sphingolipid biosynthesis genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
ALG5 YPL227C UDP-glucose:dolichyl-phosphate glucosyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI17 YDR434W Transmembrane protein genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VAC8 YEL013W Vacuole-specific Myo2p receptor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
LAS21 YJL062W Mannose-ethanolamine phosphotransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS21 YOR089C Endosomal Rab family GTPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
KEX2 YNL238W Kexin, a subtilisin-like protease (proprotein convertase) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VPS52 YDR484W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TOH1 YJL171C GPI-anchored cell wall protein of unknown function genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SED4 YCR067C Integral ER membrane protein that stimulates Sar1p GTPase activity genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
UBX2 YML013W Bridging factor involved in ER-associated protein degradation (ERAD) genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
VPS51 YKR020W Component of the GARP (Golgi-associated retrograde protein) complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI19 YDR437W Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
ERG4 YGL012W C-24(28) sterol reductase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DIE2 YGR227W Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 2 2 2 Synthetic Rescue, Positive Genetic
CHS5 YLR330W Component of the exomer complex genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
CHS6 YJL099W Member of the ChAPs (Chs5p-Arf1p-binding proteins) family genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
KAR2 YJL034W ATPase involved in protein import into the ER genetic 2 2 2 Positive Genetic, Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 2 2 2 Synthetic Growth Defect, Negative Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 2 2 2 Synthetic Lethality, Positive Genetic
PEP1 YBL017C Type I transmembrane sorting receptor for multiple vacuolar hydrolases genetic 2 2 2 Negative Genetic, Positive Genetic
PUP1 YOR157C Beta 2 subunit of the 20S proteasome genetic 2 2 2 Positive Genetic, Negative Genetic
CDC50 YCR094W Endosomal protein that interacts with phospholipid flippase Drs2p genetic 2 2 2 Negative Genetic, Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 2 1 2 Negative Genetic, Negative Genetic
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 2 1 2 Negative Genetic, Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 2 1 2 Positive Genetic, Positive Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 2 1 2 Negative Genetic, Negative Genetic
GSF2 YML048W Endoplasmic reticulum (ER) localized integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
BUB3 YOR026W Kinetochore checkpoint WD40 repeat protein genetic 2 1 2 Positive Genetic, Positive Genetic
GPI16 YHR188C Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 2 Negative Genetic, Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 2 1 2 Negative Genetic, Negative Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 2 Positive Genetic, Positive Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 2 1 2 Negative Genetic, Negative Genetic
GUP2 YPL189W Probable membrane protein genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
GUT1 YHL032C Glycerol kinase genetic 2 1 2 Phenotypic Enhancement, Phenotypic Enhancement
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 2 1 2 Negative Genetic, Negative Genetic
PTC1 YDL006W Type 2C protein phosphatase (PP2C) genetic 2 1 2 Negative Genetic, Negative Genetic
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
WBP1 YEL002C Beta subunit of the oligosaccharyl transferase glycoprotein complex genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase genetic 2 1 2 Negative Genetic, Negative Genetic
ISC1 YER019W Inositol phosphosphingolipid phospholipase C genetic 2 1 2 Positive Genetic, Positive Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 2 Negative Genetic, Negative Genetic
SLG1 YOR008C Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 2 1 2 Negative Genetic, Negative Genetic
RGD1 YBR260C GTPase-activating protein (RhoGAP) for Rho3p and Rho4p genetic 2 1 2 Negative Genetic, Negative Genetic
MID1 YNL291C Stretch-activated Ca2+-permeable cation channel genetic 2 1 2 Negative Genetic, Negative Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways genetic 2 1 2 Negative Genetic, Negative Genetic
VPS17 YOR132W Subunit of the membrane-associated retromer complex genetic 2 1 2 Negative Genetic, Negative Genetic
MKK1 YOR231W MAPKK involved in the protein kinase C signaling pathway genetic 2 1 2 Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 2 Positive Genetic, Positive Genetic
KRE9 YJL174W Glycoprotein involved in cell wall beta-glucan assembly genetic 2 1 2 Negative Genetic, Negative Genetic
RLM1 YPL089C MADS-box transcription factor genetic 2 1 2 Negative Genetic, Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 2 1 2 Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
ERR1 YOR393W Putative phosphopyruvate hydratase genetic 2 1 2 Negative Genetic, Negative Genetic
GLD1 YPR109W Component of Dsc E3 ligase complex in Golgi and endosomes genetic 2 1 2 Negative Genetic, Negative Genetic
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth physical 2 2 1 Two-hybrid, Affinity Capture-Western
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) physical 2 2 1 Affinity Capture-MS, Affinity Capture-Western
POR1 YNL055C Mitochondrial porin (voltage-dependent anion channel) genetic 2 2 1 Synthetic Rescue, Synthetic Growth Defect
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 2 1 1 Negative Genetic, Negative Genetic
EPL1 YFL024C Subunit of NuA4, an essential histone H4/H2A acetyltransferase complex genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
CDC20 YGL116W Activator of anaphase-promoting complex/cyclosome (APC/C) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 2 1 1 Positive Genetic, Positive Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes genetic 2 1 1 Negative Genetic, Negative Genetic
EPS1 YIL005W ER protein with chaperone and co-chaperone activity genetic 2 1 1 Negative Genetic, Negative Genetic
GOS1 YHL031C v-SNARE protein involved in Golgi transport genetic 2 1 1 Negative Genetic, Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 2 1 1 Negative Genetic, Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 2 1 1 Negative Genetic, Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 2 1 1 Negative Genetic, Negative Genetic
GPI2 YPL076W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 2 1 1 Negative Genetic, Negative Genetic
GAA1 YLR088W Subunit of the GPI:protein transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 2 1 1 Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 2 1 1 Negative Genetic, Negative Genetic
SCS3 YGL126W Protein required for normal ER membrane biosynthesis in response to ER genetic 2 1 1 Negative Genetic, Negative Genetic
TRS33 YOR115C Core component of TRAPP complexes I, II and IV genetic 2 1 1 Negative Genetic, Negative Genetic
SPC2 YML055W Subunit of signal peptidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
SCJ1 YMR214W One of several homologs of bacterial chaperone DnaJ genetic 2 1 1 Negative Genetic, Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 2 1 1 Negative Genetic, Negative Genetic
NEM1 YHR004C Probable catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme genetic 2 1 1 Negative Genetic, Negative Genetic
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 2 1 1 Negative Genetic, Negative Genetic
YSY6 YBR162W-A Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
YIM1 YMR152W Aldehyde reductase genetic 2 1 1 Positive Genetic, Positive Genetic
OPT1 YJL212C Proton-coupled oligopeptide transporter of the plasma membrane genetic 2 1 1 Positive Genetic, Positive Genetic
SGM1 YJR134C Protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
YJR015W YJR015W Putative protein of unknown function genetic 2 1 1 Positive Genetic, Positive Genetic
LAG1 YHL003C Ceramide synthase component genetic 2 1 1 Positive Genetic, Positive Genetic
SND3 YBR106W Involved in SRP-independent protein targeting to the ER genetic 2 1 1 Positive Genetic, Positive Genetic
YMD8 YML038C Putative nucleotide sugar transporter genetic 2 1 1 Positive Genetic, Positive Genetic
SWC4 YGR002C Component of the Swr1p complex that incorporates Htz1p into chromatin genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
IPP1 YBR011C Cytoplasmic inorganic pyrophosphatase (PPase) genetic 2 1 1 Negative Genetic, Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
YIP1 YGR172C Integral membrane protein genetic 2 1 1 Negative Genetic, Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 2 1 1 Negative Genetic, Negative Genetic
RNA1 YMR235C GTPase activating protein (GAP) for Gsp1p genetic 2 1 1 Negative Genetic, Negative Genetic
SMP3 YOR149C Alpha 1,2-mannosyltransferase genetic 2 1 1 Negative Genetic, Negative Genetic
ALG12 YNR030W Alpha-1,6-mannosyltransferase localized to the ER genetic 2 1 1 Negative Genetic, Negative Genetic
GPI15 YNL038W Protein involved in the synthesis of GlcNAc-PI genetic 2 1 1 Negative Genetic, Negative Genetic
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CLF1 YLR117C Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
CWC25 YNL245C Splicing factor required for the first step of pre-mRNA splicing genetic 1 1 1 Negative Genetic
ESF1 YDR365C Nucleolar protein involved in pre-rRNA processing genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Negative Genetic
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Negative Genetic
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 1 1 1 Negative Genetic
AAH1 YNL141W Adenine deaminase (adenine aminohydrolase) genetic 1 1 1 Positive Genetic
AAR2 YBL074C Component of the U5 snRNP complex genetic 1 1 1 Negative Genetic
APC1 YNL172W Largest subunit of the Anaphase-Promoting Complex/Cyclosome genetic 1 1 1 Positive Genetic
BET3 YKR068C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
ASC1 YMR116C G-protein beta subunit and guanine dissociation inhibitor for Gpa2p genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
CYS4 YGR155W Cystathionine beta-synthase genetic 1 1 1 Negative Genetic
DCP1 YOL149W Subunit of the Dcp1p-Dcp2p decapping enzyme complex genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
EAF3 YPR023C Component of the Rpd3S histone deacetylase complex genetic 1 1 1 Negative Genetic
EXO84 YBR102C Exocyst subunit with dual roles in exocytosis and spliceosome assembly genetic 1 1 1 Negative Genetic
FKS1 YLR342W Catalytic subunit of 1,3-beta-D-glucan synthase genetic 1 1 1 Positive Genetic
CCT4 YDL143W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
GCD7 YLR291C Beta subunit of translation initiation factor eIF2B genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
ACK1 YDL203C Protein that functions in the cell wall integrity pathway genetic 1 1 1 Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
CRM1 YGR218W Nuclear export factor, exportin genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
ATG18 YFR021W Phosphoinositide binding protein genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
GLE2 YER107C RNA export factor associated with the nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
DEP1 YAL013W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
DAL3 YIR032C Ureidoglycolate lyase genetic 1 1 1 Positive Genetic
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Negative Genetic
FET3 YMR058W Ferro-O2-oxidoreductase physical 1 1 1 PCA
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 1 1 1 Negative Genetic
CCT5 YJR064W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
CLN1 YMR199W G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
ERG10 YPL028W Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) genetic 1 1 1 Positive Genetic
COS111 YBR203W Protein required for antifungal drug ciclopirox olamine resistance genetic 1 1 1 Negative Genetic
AIP1 YMR092C Actin cortical patch component genetic 1 1 1 Negative Genetic
ERG1 YGR175C Squalene epoxidase genetic 1 1 1 Positive Genetic
FAR10 YLR238W Protein involved in recovery from arrest in response to pheromone genetic 1 1 1 Negative Genetic
CDC60 YPL160W Cytosolic leucyl tRNA synthetase genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
GPG1 YGL121C Proposed gamma subunit of the heterotrimeric G protein genetic 1 1 1 Negative Genetic
CHS1 YNL192W Chitin synthase I genetic 1 1 1 Positive Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
DAK2 YFL053W Dihydroxyacetone kinase genetic 1 1 1 Negative Genetic
FCF1 YDR339C PINc domain endonuclease genetic 1 1 1 Negative Genetic
CLN2 YPL256C G1 cyclin involved in regulation of the cell cycle genetic 1 1 1 Negative Genetic
EXO70 YJL085W Subunit of the exocyst complex genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
ATP7 YKL016C Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
FZF1 YGL254W Transcription factor involved in sulfite metabolism genetic 1 1 1 Negative Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Negative Genetic
ASK10 YGR097W Regulator of the Fps1p glycerol channel genetic 1 1 1 Negative Genetic
DSE3 YOR264W Daughter cell-specific protein, may help establish daughter fate genetic 1 1 1 Negative Genetic
CUB1 YPL260W Conserved fungal gene linked to DNA repair and proteasome function genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
AIM4 YBR194W Protein proposed to be associated with the nuclear pore complex genetic 1 1 1 Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
CCZ1 YBR131W Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
GAP1 YKR039W General amino acid permease physical 1 1 1 Affinity Capture-Western
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Positive Genetic
ARK1 YNL020C Ser/Thr protein kinase genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Negative Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
CBS2 YDR197W Mitochondrial translational activator of the COB mRNA genetic 1 1 1 Negative Genetic
FRK1 YPL141C Protein kinase of unknown cellular role physical 1 1 1 Biochemical Activity
DAL5 YJR152W Allantoate permease genetic 1 1 1 Negative Genetic
ERI1 YPL096C-A Endoplasmic reticulum membrane protein that binds and inhibits Ras2p genetic 1 1 1 Negative Genetic
EHT1 YBR177C Octanoyl-CoA:ethanol acyltransferase genetic 1 1 1 Negative Genetic
BPH1 YCR032W Protein homologous to Chediak-Higashi syndrome and Beige proteins genetic 1 1 1 Negative Genetic
BRL1 YHR036W Essential nuclear envelope/ER integral membrane protein genetic 1 1 1 Negative Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring genetic 1 1 1 Negative Genetic
BSC2 YDR275W Protein of unknown function involved in multidrug resistance genetic 1 1 1 Negative Genetic
AGE2 YIL044C ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector genetic 1 1 1 Negative Genetic
EUG1 YDR518W Protein disulfide isomerase of the endoplasmic reticulum lumen genetic 1 1 1 Negative Genetic
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response physical 1 1 1 Biochemical Activity
SAT4 YCR008W Ser/Thr protein kinase involved in salt tolerance, nutrient response genetic 1 1 1 Negative Genetic
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
YHL042W YHL042W Endoplasmic reticulum protein physical 1 1 1 PCA
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase physical 1 1 1 PCA
MSC7 YHR039C Protein of unknown function physical 1 1 1 PCA
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 Affinity Capture-MS
SBH1 YER087C-B Beta subunit of Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p) physical 1 1 1 Two-hybrid
PIL1 YGR086C Eisosome core component physical 1 1 1 Affinity Capture-Western
PIL1 YGR086C Eisosome core component genetic 1 1 1 Synthetic Growth Defect
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Lethality
SPT21 YMR179W Protein with a role in transcriptional silencing genetic 1 1 1 Synthetic Rescue
RPT2 YDL007W ATPase of the 19S regulatory particle of the 26S proteasome genetic 1 1 1 Negative Genetic
PCF11 YDR228C mRNA 3' end processing factor genetic 1 1 1 Negative Genetic
RTT103 YDR289C Protein involved in transcription termination by RNA polymerase II genetic 1 1 1 Negative Genetic
PRE9 YGR135W Alpha 3 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
SWI3 YJL176C Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
YHC1 YLR298C Component of the U1 snRNP complex required for pre-mRNA splicing genetic 1 1 1 Positive Genetic
ORM2 YLR350W Protein that mediates sphingolipid homeostasis genetic 1 1 1 Negative Genetic
SNO4 YMR322C Possible chaperone and cysteine protease genetic 1 1 1 Negative Genetic
RIA1 YNL163C Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis genetic 1 1 1 Negative Genetic
HAL5 YJL165C Snf1p-related nutrient-responsive protein kinase genetic 1 1 1 Dosage Rescue
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
VPS27 YNR006W Endosomal protein that forms a complex with Hse1p genetic 1 1 1 Positive Genetic
TOS7 YOL019W Protein involved in secretion and cell wall organization genetic 1 1 1 Negative Genetic
VPS41 YDR080W Subunit of the HOPS endocytic tethering complex genetic 1 1 1 Negative Genetic
WHI2 YOR043W Negative regulator of TORC1 in response to limiting leucine genetic 1 1 1 Negative Genetic
VPS5 YOR069W Nexin-1 homolog genetic 1 1 1 Negative Genetic
YPT53 YNL093W Stress-induced Rab family GTPase genetic 1 1 1 Negative Genetic
SKM1 YOL113W Member of the PAK family of serine/threonine protein kinases genetic 1 1 1 Negative Genetic
PBS2 YJL128C MAP kinase kinase of the HOG signaling pathway genetic 1 1 1 Negative Genetic
PRM8 YGL053W Pheromone-regulated protein genetic 1 1 1 Negative Genetic
PDC1 YLR044C Major of three pyruvate decarboxylase isozymes genetic 1 1 1 Positive Genetic
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Negative Genetic
QNS1 YHR074W Glutamine-dependent NAD(+) synthetase genetic 1 1 1 Positive Genetic
INM1 YHR046C Inositol monophosphatase genetic 1 1 1 Negative Genetic
KCS1 YDR017C Inositol hexakisphosphate and inositol heptakisphosphate kinase genetic 1 1 1 Positive Genetic
SPE1 YKL184W Ornithine decarboxylase genetic 1 1 1 Positive Genetic
TRR1 YDR353W Cytoplasmic thioredoxin reductase genetic 1 1 1 Positive Genetic
HEM3 YDL205C Porphobilinogen deaminase genetic 1 1 1 Positive Genetic
TKL1 YPR074C Transketolase genetic 1 1 1 Positive Genetic
ODC1 YPL134C Mitochondrial inner membrane transporter genetic 1 1 1 Positive Genetic
HXT3 YDR345C Low affinity glucose transporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
NHA1 YLR138W Na+/H+ antiporter genetic 1 1 1 Positive Genetic
KTR6 YPL053C Probable mannosylphosphate transferase genetic 1 1 1 Positive Genetic
MET14 YKL001C Adenylylsulfate kinase genetic 1 1 1 Negative Genetic
STL1 YDR536W Glycerol proton symporter of the plasma membrane genetic 1 1 1 Negative Genetic
GUT2 YIL155C Mitochondrial glycerol-3-phosphate dehydrogenase genetic 1 1 1 Phenotypic Enhancement
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Synthetic Growth Defect
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
SEC13 YLR208W Structural component of 3 complexes genetic 1 1 1 Synthetic Rescue
TTI1 YKL033W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Positive Genetic
SUR2 YDR297W Sphinganine C4-hydroxylase genetic 1 1 1 Positive Genetic
LIP1 YMR298W Ceramide synthase subunit genetic 1 1 1 Positive Genetic
PEP7 YDR323C Adaptor protein involved in vesicle-mediated vacuolar protein sorting genetic 1 1 1 Negative Genetic
SHR3 YDL212W Endoplasmic reticulum packaging chaperone genetic 1 1 1 Positive Genetic
NCP1 YHR042W NADP-cytochrome P450 reductase genetic 1 1 1 Positive Genetic
KRE2 YDR483W Alpha1,2-mannosyltransferase of the Golgi genetic 1 1 1 Negative Genetic
RAM2 YKL019W Alpha subunit of farnesyltransferase and geranylgeranyltransferase-I genetic 1 1 1 Negative Genetic
SKN7 YHR206W Nuclear response regulator and transcription factor genetic 1 1 1 Negative Genetic
SEC72 YLR292C Non-essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
MNN2 YBR015C Alpha-1,2-mannosyltransferase genetic 1 1 1 Negative Genetic
MNN11 YJL183W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 1 1 1 Negative Genetic
YUR1 YJL139C Mannosyltransferase involved in protein N-glycosylation genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Positive Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
PGM1 YKL127W Phosphoglucomutase, minor isoform genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
YPT31 YER031C Rab family GTPase genetic 1 1 1 Negative Genetic
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
RIM21 YNL294C pH sensor molecule, component of the RIM101 pathway genetic 1 1 1 Negative Genetic
TSC13 YDL015C Enoyl reductase genetic 1 1 1 Positive Genetic
PSA1 YDL055C GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase) genetic 1 1 1 Positive Genetic
TSC10 YBR265W 3-ketosphinganine reductase genetic 1 1 1 Positive Genetic
SEC18 YBR080C AAA ATPase and SNARE disassembly chaperone genetic 1 1 1 Positive Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Positive Genetic
PFY1 YOR122C Profilin genetic 1 1 1 Positive Genetic
SED1 YDR077W Major stress-induced structural GPI-cell wall glycoprotein genetic 1 1 1 Negative Genetic
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins genetic 1 1 1 Negative Genetic
SEC1 YDR164C Sm-like protein involved in docking and fusion of exocytic vesicles genetic 1 1 1 Positive Genetic
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Positive Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Positive Genetic
SSC1 YJR045C Hsp70 family ATPase genetic 1 1 1 Positive Genetic
PGA2 YNL149C Essential protein required for maturation of Gas1p and Pho8p genetic 1 1 1 Positive Genetic
PRP46 YPL151C Member of the NineTeen Complex (NTC) genetic 1 1 1 Positive Genetic
SUP35 YDR172W Translation termination factor eRF3 genetic 1 1 1 Positive Genetic
OST4 YDL232W Subunit of the oligosaccharyltransferase complex of the ER lumen genetic 1 1 1 Positive Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
YCR090C YCR090C Putative protein of unknown function genetic 1 1 1 Positive Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Positive Genetic
PEP8 YJL053W Vacuolar protein component of the retromer genetic 1 1 1 Positive Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Positive Genetic
VPS13 YLL040C Lipid transport protein involved in prospore membrane morphogenesis genetic 1 1 1 Positive Genetic
VPS71 YML041C Nucleosome-binding component of the SWR1 complex genetic 1 1 1 Positive Genetic
HAP5 YOR358W Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex genetic 1 1 1 Positive Genetic
YHR050W-A YHR050W-A Protein of unknown function genetic 1 1 1 Positive Genetic
MEF2 YJL102W Mitochondrial elongation factor involved in translational elongation genetic 1 1 1 Positive Genetic
LHS1 YKL073W Molecular chaperone of the endoplasmic reticulum lumen genetic 1 1 1 Positive Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Positive Genetic
TCB3 YML072C Cortical ER protein involved in ER-plasma membrane tethering genetic 1 1 1 Positive Genetic
VAN1 YML115C Component of the mannan polymerase I genetic 1 1 1 Positive Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Positive Genetic
ZWF1 YNL241C Glucose-6-phosphate dehydrogenase (G6PD) genetic 1 1 1 Positive Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Positive Genetic
YOR381W-A YOR381W-A Putative protein of unknown function genetic 1 1 1 Positive Genetic
NCB2 YDR397C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
SPP41 YDR464W Protein of unknown function genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Negative Genetic
TUB2 YFL037W Beta-tubulin genetic 1 1 1 Negative Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
YHR020W YHR020W Prolyl-tRNA synthetase genetic 1 1 1 Negative Genetic
RPF1 YHR088W Protein involved in assembly and export of the large ribosomal subunit genetic 1 1 1 Negative Genetic
TAO3 YIL129C Component of the RAM signaling network genetic 1 1 1 Negative Genetic
LSM8 YJR022W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
MPE1 YKL059C Subunit of CPF cleavage and polyadenylation factor and E3 Ub-ligase genetic 1 1 1 Negative Genetic
RPP0 YLR340W Conserved ribosomal protein P0 of the ribosomal stalk genetic 1 1 1 Negative Genetic
UTP15 YMR093W Nucleolar protein genetic 1 1 1 Negative Genetic
RPC19 YNL113W RNA polymerase subunit AC19 genetic 1 1 1 Negative Genetic
SSU72 YNL222W Phosphatase and transcription/RNA-processing factor genetic 1 1 1 Negative Genetic
KRI1 YNL308C Essential nucleolar protein required for 40S ribosome biogenesis genetic 1 1 1 Negative Genetic
TPT1 YOL102C tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing genetic 1 1 1 Negative Genetic
NOB1 YOR056C Protein involved in proteasomal and 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
TFB2 YPL122C Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
TFB4 YPR056W Subunit of TFIIH complex genetic 1 1 1 Negative Genetic
MRD1 YPR112C Essential conserved small ribosomal subunit (40s) synthesis factor genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
MCM7 YBR202W Component of the Mcm2-7 hexameric helicase complex genetic 1 1 1 Negative Genetic
QRI1 YDL103C UDP-N-acetylglucosamine pyrophosphorylase genetic 1 1 1 Negative Genetic
MAK21 YDR060W Constituent of 66S pre-ribosomal particles genetic 1 1 1 Negative Genetic
SLU7 YDR088C RNA splicing factor genetic 1 1 1 Negative Genetic
MSS4 YDR208W Phosphatidylinositol-4-phosphate 5-kinase genetic 1 1 1 Negative Genetic
UTP5 YDR398W Subunit of U3-containing Small Subunit (SSU) processome complex genetic 1 1 1 Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 1 1 1 Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 1 1 1 Negative Genetic
RSC9 YML127W Component of the RSC chromatin remodeling complex genetic 1 1 1 Negative Genetic
TAF7 YMR227C TFIID subunit (67 kDa) genetic 1 1 1 Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
RAV2 YDR202C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 1 1 1 Negative Genetic
RPS18A YDR450W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase genetic 1 1 1 Negative Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
SWP82 YFL049W Member of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
PSK1 YAL017W PAS domain-containing serine/threonine protein kinase genetic 1 1 1 Negative Genetic
SHE1 YBL031W Mitotic spindle protein genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
YCR007C YCR007C Putative integral membrane protein genetic 1 1 1 Negative Genetic
NUR1 YDL089W Protein involved in regulation of mitotic exit genetic 1 1 1 Negative Genetic
NOP6 YDL213C rRNA-binding protein required for 40S ribosomal subunit biogenesis genetic 1 1 1 Negative Genetic
SNF11 YDR073W Subunit of the SWI/SNF chromatin remodeling complex genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
HKR1 YDR420W Mucin family member that functions as an osmosensor in the HOG pathway genetic 1 1 1 Negative Genetic
PUF6 YDR496C Pumilio-homology domain protein genetic 1 1 1 Negative Genetic
YFL051C YFL051C Putative protein of unknown function genetic 1 1 1 Negative Genetic
PHO4 YFR034C Basic helix-loop-helix (bHLH) transcription factor of the myc-family genetic 1 1 1 Negative Genetic
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex genetic 1 1 1 Negative Genetic
YIA6 YIL006W Mitochondrial NAD+ transporter genetic 1 1 1 Negative Genetic
POT1 YIL160C 3-ketoacyl-CoA thiolase with broad chain length specificity genetic 1 1 1 Negative Genetic
MND2 YIR025W Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
HYR1 YIR037W Glutathione peroxidase genetic 1 1 1 Negative Genetic
SDH9 YJL045W Minor succinate dehydrogenase isozyme genetic 1 1 1 Negative Genetic
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis genetic 1 1 1 Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
PIR5 YJL160C Putative protein of unknown function genetic 1 1 1 Negative Genetic
IME1 YJR094C Master regulator of meiosis that is active only during meiotic events genetic 1 1 1 Negative Genetic
RPL43B YJR094W-A Ribosomal 60S subunit protein L43B genetic 1 1 1 Negative Genetic
RPL14A YKL006W Ribosomal 60S subunit protein L14A genetic 1 1 1 Negative Genetic
MUD2 YKL074C Protein involved in early pre-mRNA splicing genetic 1 1 1 Negative Genetic
SSH4 YKL124W Specificity factor required for Rsp5p-dependent ubiquitination genetic 1 1 1 Negative Genetic
IRS4 YKR019C EH domain-containing protein genetic 1 1 1 Negative Genetic
SAP190 YKR028W Protein that forms a complex with the Sit4p protein phosphatase genetic 1 1 1 Negative Genetic
SET3 YKR029C Defining member of the SET3 histone deacetylase complex genetic 1 1 1 Negative Genetic
HSP104 YLL026W Disaggregase genetic 1 1 1 Negative Genetic
RPL8B YLL045C Ribosomal 60S subunit protein L8A genetic 1 1 1 Negative Genetic
UBR2 YLR024C Cytoplasmic ubiquitin-protein ligase (E3) genetic 1 1 1 Negative Genetic
SND2 YLR065C Protein involved in SRP-independent targeting of substrates to the ER genetic 1 1 1 Negative Genetic
YLR225C YLR225C Putative protein of unknown function genetic 1 1 1 Negative Genetic
MSC1 YML128C Protein of unknown function genetic 1 1 1 Negative Genetic
UBX4 YMR067C UBX domain-containing protein that interacts with Cdc48p genetic 1 1 1 Negative Genetic
MUB1 YMR100W MYND domain-containing protein genetic 1 1 1 Negative Genetic
MME1 YMR166C Transporter of the mitochondrial inner membrane that exports magnesium genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
RAD14 YMR201C Subunit of Nucleotide Excision Repair Factor 1 (NEF1) genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SSK2 YNR031C MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway genetic 1 1 1 Negative Genetic
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes genetic 1 1 1 Negative Genetic
WHI5 YOR083W Repressor of G1 transcription genetic 1 1 1 Negative Genetic
SNC2 YOR327C Vesicle membrane receptor protein (v-SNARE) genetic 1 1 1 Negative Genetic
UBC11 YOR339C Ubiquitin-conjugating enzyme genetic 1 1 1 Negative Genetic
RAD1 YPL022W Single-stranded DNA endonuclease (with Rad10p) genetic 1 1 1 Negative Genetic
MDL2 YPL270W Mitochondrial inner membrane half-type ABC transporter genetic 1 1 1 Negative Genetic
YPR078C YPR078C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR161W-C YGR161W-C Putative protein of unknown function genetic 1 1 1 Negative Genetic
OSH7 YHR001W Oxysterol-binding phosphatidylserine transferase genetic 1 1 1 Negative Genetic
PPE1 YHR075C Protein with carboxyl methyl esterase activity genetic 1 1 1 Negative Genetic
MTG2 YHR168W Putative GTPase genetic 1 1 1 Negative Genetic
ROF1 YHR177W Putative transcription factor containing a WOPR domain genetic 1 1 1 Negative Genetic
YIL102C YIL102C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YKR015C YKR015C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
YKU80 YMR106C Subunit of telomeric Ku complex (Yku70p-Yku80p) genetic 1 1 1 Phenotypic Enhancement
RUD3 YOR216C Golgi matrix protein genetic 1 1 1 Positive Genetic
SSP2 YOR242C Sporulation specific protein that localizes to the spore wall genetic 1 1 1 Positive Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Positive Genetic
PRR1 YKL116C Serine/threonine protein kinase genetic 1 1 1 Negative Genetic
STT4 YLR305C Phosphatidylinositol-4-kinase genetic 1 1 1 Negative Genetic
ECM7 YLR443W Putative integral membrane protein with a role in calcium uptake genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Positive Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Positive Genetic
AST2 YER101C Lipid raft associated protein genetic 1 1 1 Negative Genetic
CIS3 YJL158C Mannose-containing glycoprotein constituent of the cell wall genetic 1 1 1 Negative Genetic
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Positive Genetic
DAL2 YIR029W Allantoicase genetic 1 1 1 Negative Genetic
CDS1 YBR029C Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase) genetic 1 1 1 Positive Genetic
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
GPI14 YJR013W Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I genetic 1 1 1 Negative Genetic
CDC8 YJR057W Nucleoside monophosphate and nucleoside diphosphate kinase genetic 1 1 1 Negative Genetic
GPI18 YBR004C Functional ortholog of human PIG-V genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
ECM9 YKR004C Non-essential protein of unknown function genetic 1 1 1 Positive Genetic
ECM4 YKR076W S-glutathionyl-(chloro)hydroquinone reductase (GS-HQR) genetic 1 1 1 Positive Genetic
CRD1 YDL142C Cardiolipin synthase genetic 1 1 1 Synthetic Lethality
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
AVT7 YIL088C Vacuolar amino acid transporter genetic 1 1 1 Negative Genetic
AGP1 YCL025C Broad-specificity, low-affinity amino acid permease genetic 1 1 1 Negative Genetic
GPI1 YGR216C Membrane protein involved in the synthesis of GlcNAc-PI genetic 1 1 1 Negative Genetic
DAL4 YIR028W Allantoin permease genetic 1 1 1 Positive Genetic
CIN10 YDR387C Putative transporter genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
ARG7 YMR062C Mitochondrial ornithine acetyltransferase genetic 1 1 1 Positive Genetic