| SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
11 |
3 |
7 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
physical |
10 |
6 |
6 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, Reconstituted Complex, Co-purification, Co-purification, Co-crystal Structure, Reconstituted Complex, Affinity Capture-Western |
| CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
9 |
3 |
8 |
Synthetic Lethality, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
9 |
3 |
5 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic, Negative Genetic, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
8 |
2 |
6 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
6 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
5 |
2 |
5 |
Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Synthetic Growth Defect |
| ILM1 |
YJR118C |
Protein of unknown function |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| BUD7 |
YOR299W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
physical |
5 |
2 |
4 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western |
| TPM1 |
YNL079C |
Major isoform of tropomyosin |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Co-purification, Affinity Capture-Western, Affinity Capture-Western |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Affinity Capture-Western |
| CHS3 |
YBR023C |
Chitin synthase III |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex |
| MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
4 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect, Synthetic Growth Defect |
| BEM2 |
YER155C |
Rho GTPase activating protein (RhoGAP) |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| CYK3 |
YDL117W |
SH3-domain protein located in the bud neck and cytokinetic actin ring |
genetic |
4 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
| VAN1 |
YML115C |
Component of the mannan polymerase I |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
| APL2 |
YKL135C |
Beta-adaptin subunit of the clathrin-associated protein (AP-1) complex |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Phenotypic Suppression, Phenotypic Suppression |
| ARC18 |
YLR370C |
Subunit of the ARP2/3 complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
| ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
| ARP2 |
YDL029W |
Essential component of the Arp2/3 complex |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
| BNI1 |
YNL271C |
Formin |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
| GAS1 |
YMR307W |
Beta-1,3-glucanosyltransferase required for cell wall assembly |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
| RPO41 |
YFL036W |
Mitochondrial RNA polymerase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
| KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| ARV1 |
YLR242C |
Cortical ER protein |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Synthetic Lethality, Synthetic Growth Defect |
| PFY1 |
YOR122C |
Profilin |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
| BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CMD1 |
YBR109C |
Calmodulin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SSD1 |
YDR293C |
Translational repressor |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RAD51 |
YER095W |
Strand exchange protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| FLX1 |
YIL134W |
Mitochondrial flavin adenine dinucleotide transporter |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| EXO1 |
YOR033C |
5'-3' exonuclease and flap-endonuclease |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
3 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect, Synthetic Growth Defect |
| PAN1 |
YIR006C |
Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| AVL9 |
YLR114C |
Conserved protein involved in exocytic transport from the Golgi |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
| CHC1 |
YGL206C |
Clathrin heavy chain |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Lethality |
| APM1 |
YPL259C |
Mu1-like medium subunit of the AP-1 complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Suppression |
| APL4 |
YPR029C |
Gamma-adaptin |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Lethality |
| BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
2 |
2 |
2 |
Phenotypic Enhancement, Negative Genetic |
| MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
| ENT3 |
YJR125C |
Protein containing an N-terminal epsin-like domain |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Positive Genetic |
| ENT5 |
YDR153C |
Protein containing an N-terminal epsin-like domain |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Synthetic Growth Defect |
| GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
| CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CDC3 |
YLR314C |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATG20 |
YDL113C |
Sorting nexin family member |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BUD8 |
YLR353W |
Protein involved in bud-site selection |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
physical |
2 |
1 |
2 |
Affinity Capture-Western, Affinity Capture-Western |
| SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SEC9 |
YGR009C |
t-SNARE protein required for secretory vesicle-plasma membrane fusion |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| FTH1 |
YBR207W |
Putative high affinity iron transporter |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| GEA1 |
YJR031C |
Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| KTI12 |
YKL110C |
Protein that plays a role in modification of tRNA wobble nucleosides |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| CYT2 |
YKL087C |
Cytochrome c1 heme lyase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SKA1 |
YKL023W |
SKI complex-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SMF3 |
YLR034C |
Putative divalent metal ion transporter involved in iron homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| HMG2 |
YLR450W |
HMG-CoA reductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MSN5 |
YDR335W |
Karyopherin |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| NUP133 |
YKR082W |
Subunit of Nup84p subcomplex of nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Synthetic Growth Defect, Synthetic Growth Defect |
| SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| ATR2 |
YMR279C |
Putative boron transporter involved in boron efflux and resistance |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
| COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
2 |
1 |
Negative Genetic, Positive Genetic |
| ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MPS3 |
YJL019W |
Nuclear envelope protein |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
| MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SRV2 |
YNL138W |
CAP (cyclase-associated protein) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| MYO2 |
YOR326W |
Type V myosin motor involved in actin-based transport of cargos |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
| SPT10 |
YJL127C |
Histone H3 acetylase with a role in transcriptional regulation |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
| YAP6 |
YDR259C |
Basic leucine zipper (bZIP) transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| TFC7 |
YOR110W |
RNA pol III transcription initiation factor complex (TFIIIC) subunit |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| UGA3 |
YDL170W |
Transcriptional activator for GABA-dependent induction of GABA genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
| ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ARC15 |
YIL062C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
| ACE2 |
YLR131C |
Transcription factor required for septum destruction after cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| ARF1 |
YDL192W |
ADP-ribosylation factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP7 |
YKL016C |
Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ASK10 |
YGR097W |
Regulator of the Fps1p glycerol channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS3 |
YBR023C |
Chitin synthase III |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| AKR1 |
YDR264C |
Palmitoyl transferase involved in protein palmitoylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| BCS1 |
YDR375C |
Protein translocase and chaperone required for Complex III assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| BAR1 |
YIL015W |
Aspartyl protease secreted to periplasmic space of mating type a cell |
genetic |
1 |
1 |
1 |
Negative Genetic |
| APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| AIM26 |
YKL037W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GRH1 |
YDR517W |
Acetylated cis-Golgi protein, homolog of human GRASP65 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| TEF1 |
YPR080W |
Translational elongation factor EF-1 alpha |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
| NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
| PIN2 |
YOR104W |
Exomer-dependent cargo protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
| SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
| UBI4 |
YLL039C |
Ubiquitin |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| CHS7 |
YHR142W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| GGA1 |
YDR358W |
Golgi-localized protein with homology to gamma-adaptin |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| GGA2 |
YHR108W |
Protein that regulates Arf1p, Arf2p to facilitate Golgi trafficking |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| DRS2 |
YAL026C |
Trans-golgi network aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
| WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| YBR287W |
YBR287W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPS16B |
YDL083C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RPL24A |
YGL031C |
Ribosomal 60S subunit protein L24A |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PCP1 |
YGR101W |
Mitochondrial serine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSF1 |
YMR030W |
Protein required for respiratory growth |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POC4 |
YPL144W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
| VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
| ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| IRC6 |
YFR043C |
Clathrin coat accessory factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| YPT31 |
YER031C |
Rab family GTPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
| GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| DNF1 |
YER166W |
Aminophospholipid translocase (flippase) |
genetic |
1 |
1 |
1 |
Dosage Rescue |
| COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP9 |
YDL030W |
Subunit of the SF3a splicing factor complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| QRI1 |
YDL103C |
UDP-N-acetylglucosamine pyrophosphorylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
1 |
1 |
1 |
Positive Genetic |
| PRP19 |
YLL036C |
Splicing factor associated with the spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
| NBP1 |
YLR457C |
Spindle pole body (SPB) component |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| OAC1 |
YKL120W |
Mitochondrial inner membrane transporter |
genetic |
1 |
1 |
1 |
Positive Genetic |
| DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IPP1 |
YBR011C |
Cytoplasmic inorganic pyrophosphatase (PPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSC6 |
YCR052W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| POL3 |
YDL102W |
Catalytic subunit of DNA polymerase delta |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MSS4 |
YDR208W |
Phosphatidylinositol-4-phosphate 5-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VRG4 |
YGL225W |
Golgi GDP-mannose transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UGP1 |
YKL035W |
UDP-glucose pyrophosphorylase (UGPase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| EXO84 |
YBR102C |
Exocyst subunit with dual roles in exocytosis and spliceosome assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
| MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SYF1 |
YDR416W |
Member of the NineTeen Complex (NTC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SCL1 |
YGL011C |
Alpha 1 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
| STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SMD1 |
YGR074W |
Core Sm protein Sm D1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SHQ1 |
YIL104C |
Chaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CLP1 |
YOR250C |
Component of the cleavage and polyadenylation factor I (CF I) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| QRI7 |
YDL104C |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PHB2 |
YGR231C |
Subunit of the prohibitin complex (Phb1p-Phb2p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
| DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VHS3 |
YOR054C |
Negative regulatory subunit of protein phosphatase 1 Ppz1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
| RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PUT7 |
YLR283W |
Regulator of mitochondrial proline metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
| TUS1 |
YLR425W |
Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
| UFO1 |
YML088W |
F-box receptor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| FAR3 |
YMR052W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC7 |
YDR170C |
Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors |
genetic |
1 |
1 |
1 |
Negative Genetic |
| COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
| USO1 |
YDL058W |
Essential protein involved in vesicle-mediated ER to Golgi transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
| SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
| PAC1 |
YOR269W |
Regulator of dynein, involved in intracellular transport |
genetic |
1 |
1 |
1 |
Positive Genetic |
| GPI19 |
YDR437W |
Subunit of GPI-GlcNAc transferase involved in synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Positive Genetic |
| RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Positive Genetic |
| TRS65 |
YGR166W |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CST9 |
YLR394W |
SUMO E3 ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| IES4 |
YOR189W |
Component of the INO80 chromatiin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
| STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
| NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AGE2 |
YIL044C |
ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC50 |
YCR094W |
Endosomal protein that interacts with phospholipid flippase Drs2p |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
| CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
| AIM34 |
YMR003W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
| CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
1 |
1 |
1 |
Negative Genetic |
| CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
| ATP23 |
YNR020C |
Putative metalloprotease of the mitochondrial inner membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
