RVS161 |
YCR009C |
Amphiphysin-like lipid raft protein |
genetic |
6 |
3 |
5 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
CHS5 |
YLR330W |
Component of the exomer complex |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
CHS7 |
YHR142W |
Protein of unknown function |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
5 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
5 |
2 |
4 |
Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
PSK2 |
YOL045W |
PAS-domain containing serine/threonine protein kinase |
genetic |
5 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
physical |
5 |
3 |
3 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid |
SLT2 |
YHR030C |
Serine/threonine MAP kinase |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
SKT5 |
YBL061C |
Activator of Chs3p (chitin synthase III) during vegetative growth |
genetic |
4 |
3 |
4 |
Synthetic Lethality, Negative Genetic, Synthetic Growth Defect, Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
4 |
2 |
4 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HSL1 |
YKL101W |
Nim1p-related protein kinase |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SWI4 |
YER111C |
DNA binding component of the SBF complex (Swi4p-Swi6p) |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BCK1 |
YJL095W |
MAPKKK acting in the protein kinase C signaling pathway |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
MMR1 |
YLR190W |
Phosphorylated protein of the mitochondrial outer membrane |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
BRE5 |
YNR051C |
Ubiquitin protease cofactor |
genetic |
4 |
1 |
4 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CDC10 |
YCR002C |
Component of the septin ring, required for cytokinesis |
genetic |
4 |
2 |
3 |
Negative Genetic, Negative Genetic, Positive Genetic, Negative Genetic |
MNN9 |
YPL050C |
Subunit of Golgi mannosyltransferase complex |
physical |
4 |
2 |
3 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS |
RVS167 |
YDR388W |
Calmodulin-binding actin-associated protein |
genetic |
4 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Synthetic Lethality, Negative Genetic |
VAC14 |
YLR386W |
Enzyme regulator |
genetic |
4 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic |
CHS6 |
YJL099W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
4 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ORM2 |
YLR350W |
Protein that mediates sphingolipid homeostasis |
genetic |
4 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
ANP1 |
YEL036C |
Subunit of the alpha-1,6 mannosyltransferase complex |
physical |
4 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
CMD1 |
YBR109C |
Calmodulin |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Negative Genetic, Positive Genetic |
CHS3 |
YBR023C |
Chitin synthase III |
genetic |
3 |
3 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Synthetic Growth Defect |
GIM5 |
YML094W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Growth Defect, Synthetic Lethality |
POL32 |
YJR043C |
Third subunit of DNA polymerase delta |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Synthetic Lethality, Negative Genetic |
OPI3 |
YJR073C |
Methylene-fatty-acyl-phospholipid synthase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
YPT6 |
YLR262C |
Rab family GTPase |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
TLG2 |
YOL018C |
Syntaxin-like t-SNARE |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
UBP3 |
YER151C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
GIM4 |
YEL003W |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
3 |
2 |
3 |
Negative Genetic, Synthetic Growth Defect, Negative Genetic |
ALG8 |
YOR067C |
Glucosyl transferase |
genetic |
3 |
2 |
3 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
ARL1 |
YBR164C |
Soluble GTPase with a role in regulation of membrane traffic |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC28 |
YIL076W |
Epsilon-COP subunit of the coatomer |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PHO23 |
YNL097C |
Component of the Rpd3L histone deacetylase complex |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
SSK2 |
YNR031C |
MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
ELM1 |
YKL048C |
Serine/threonine protein kinase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
HOG1 |
YLR113W |
Mitogen-activated protein kinase involved in osmoregulation |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CLN3 |
YAL040C |
G1 cyclin involved in cell cycle progression |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
BNI4 |
YNL233W |
Targeting subunit for Glc7p protein phosphatase |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
CSF1 |
YLR087C |
Protein with structural similarity to lipid transport protein Vps13p |
genetic |
3 |
1 |
3 |
Negative Genetic, Negative Genetic, Negative Genetic |
PKR1 |
YMR123W |
V-ATPase assembly factor |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
UBC4 |
YBR082C |
Ubiquitin-conjugating enzyme (E2) |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
SEC72 |
YLR292C |
Non-essential subunit of Sec63 complex |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MVP1 |
YMR004W |
Protein required for sorting proteins to the vacuole |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MRL1 |
YPR079W |
Membrane protein |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
HOC1 |
YJR075W |
Alpha-1,6-mannosyltransferase |
genetic |
3 |
1 |
2 |
Positive Genetic, Positive Genetic, Positive Genetic |
LAS21 |
YJL062W |
Mannose-ethanolamine phosphotransferase |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
HSP60 |
YLR259C |
Tetradecameric mitochondrial chaperonin |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
MBP1 |
YDL056W |
Transcription factor |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SED1 |
YDR077W |
Major stress-induced structural GPI-cell wall glycoprotein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
UBP6 |
YFR010W |
Ubiquitin-specific protease |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
SUR1 |
YPL057C |
Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
NBP2 |
YDR162C |
Protein involved in the HOG (high osmolarity glycerol) pathway |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SYN8 |
YAL014C |
Endosomal SNARE related to mammalian syntaxin 8 |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
SSK1 |
YLR006C |
Cytoplasmic phosphorelay intermediate osmosensor and regulator |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
PDR3 |
YBL005W |
Transcriptional activator of the pleiotropic drug resistance network |
genetic |
2 |
2 |
2 |
Positive Genetic, Phenotypic Enhancement |
SAP4 |
YGL229C |
Protein required for function of the Sit4p protein phosphatase |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
2 |
2 |
Negative Genetic, Positive Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
HAL5 |
YJL165C |
Snf1p-related nutrient-responsive protein kinase |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
CLN2 |
YPL256C |
G1 cyclin involved in regulation of the cell cycle |
genetic |
2 |
2 |
2 |
Negative Genetic, Synthetic Growth Defect |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CAP2 |
YIL034C |
Beta subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Synthetic Growth Defect |
ALG6 |
YOR002W |
ER-luminal alpha 1,3 glucosyltransferase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic |
CCW12 |
YLR110C |
Cell wall mannoprotein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
GWT1 |
YJL091C |
Protein involved in the inositol acylation of GlcN-PI |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM3 |
YLR438C-A |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LSM6 |
YDR378C |
Lsm (Like Sm) protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
LRP1 |
YHR081W |
Nuclear exosome-associated nucleic acid binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARO1 |
YDR127W |
Pentafunctional arom protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BEM1 |
YBR200W |
Protein containing SH3-domains |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DOA1 |
YKL213C |
WD-repeat protein involved in ubiquitin-mediated protein degradation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EDE1 |
YBL047C |
Scaffold protein involved in the formation of early endocytic sites |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FAB1 |
YFR019W |
1-phosphatidylinositol-3-phosphate 5-kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
genetic |
2 |
1 |
2 |
Synthetic Lethality, Synthetic Lethality |
SWI6 |
YLR182W |
Transcription cofactor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPA34 |
YJL148W |
RNA polymerase I subunit A34.5 |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RFA2 |
YNL312W |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VRP1 |
YLR337C |
Verprolin, proline-rich actin-associated protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TMA20 |
YER007C-A |
Protein of unknown function that associates with ribosomes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MON1 |
YGL124C |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SOH1 |
YGL127C |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RXT2 |
YBR095C |
Component of the histone deacetylase Rpd3L complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VID22 |
YLR373C |
G-quadruplex (G4) DNA binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RIC1 |
YLR039C |
Protein involved in retrograde transport to the cis-Golgi network |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWD3 |
YBR175W |
Essential subunit of the COMPASS (Set1C) complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YBL036C |
YBL036C |
Putative non-specific single-domain racemase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
SKN7 |
YHR206W |
Nuclear response regulator and transcription factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PIK1 |
YNL267W |
Phosphatidylinositol 4-kinase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
PKC1 |
YBL105C |
Protein serine/threonine kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBP14 |
YBR058C |
Ubiquitin-specific protease |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC66 |
YBR171W |
Non-essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RGD1 |
YBR260C |
GTPase-activating protein (RhoGAP) for Rho3p and Rho4p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YIH1 |
YCR059C |
Negative regulator of eIF2 kinase Gcn2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TRM3 |
YDL112W |
2'-O-ribose methyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTR2 |
YEL040W |
Chitin transglycosylase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
WBP1 |
YEL002C |
Beta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YND1 |
YER005W |
Apyrase with wide substrate specificity |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
YPT31 |
YER031C |
Rab family GTPase |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEH1 |
YGL100W |
Subunit of the Nup84 nuclear pore and SEACAT subcomplexes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS25A |
YGR027C |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SPR3 |
YGR059W |
Sporulation-specific homolog of the CDC3/10/11/12 family of genes |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UBR1 |
YGR184C |
E3 ubiquitin ligase (N-recognin) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NEO1 |
YIL048W |
Phospholipid translocase (flippase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SGN1 |
YIR001C |
Cytoplasmic RNA-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
UTR1 |
YJR049C |
ATP-NADH kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
STR2 |
YJR130C |
Cystathionine gamma-synthase, converts cysteine into cystathionine |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
TOR2 |
YKL203C |
PIK-related protein kinase and rapamycin target |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PTK1 |
YKL198C |
Putative serine/threonine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PRP16 |
YKR086W |
DEAH-box RNA helicase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RPS28B |
YLR264W |
Protein component of the small (40S) ribosomal subunit |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
VIP1 |
YLR410W |
Bifunctional inositol pyrophosphate kinase and phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP188 |
YML103C |
Subunit of the inner ring of the nuclear pore complex (NPC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SWP1 |
YMR149W |
Delta subunit of the oligosaccharyl transferase glycoprotein complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PAH1 |
YMR165C |
Mg2+-dependent phosphatidate (PA) phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RAP1 |
YNL216W |
Essential DNA-binding transcription regulator that binds many loci |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PBR1 |
YNL181W |
Putative oxidoreductase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PSD1 |
YNL169C |
Phosphatidylserine decarboxylase of the mitochondrial inner membrane |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
RAS2 |
YNL098C |
GTP-binding protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
PYP1 |
YNL010W |
Sugar alcohol phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MSO1 |
YNR049C |
Lipid-interacting protein in SNARE complex assembly machinery |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OST3 |
YOR085W |
Gamma subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
OST2 |
YOR103C |
Epsilon subunit of the oligosaccharyltransferase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
RGA1 |
YOR127W |
GTPase-activating protein for polarity-regulator Cdc42p (RhoGAP) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SKI3 |
YPR189W |
Ski complex component and TPR protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CNB1 |
YKL190W |
Calcineurin B |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ERG10 |
YPL028W |
Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUL1 |
YMR275C |
Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MIH1 |
YMR036C |
Protein tyrosine phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ECM33 |
YBR078W |
GPI-anchored protein involved in efficient glucose uptake |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
EXG1 |
YLR300W |
Major exo-1,3-beta-glucanase of the cell wall |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
APL4 |
YPR029C |
Gamma-adaptin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
AIM3 |
YBR108W |
Protein that inhibits barbed-end actin filament elongation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GPI16 |
YHR188C |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG6 |
YNL041C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CET1 |
YPL228W |
RNA 5'-triphosphatase involved in mRNA 5' capping |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DAL81 |
YIR023W |
Positive regulator of genes in multiple nitrogen degradation pathways |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IES2 |
YNL215W |
Protein that associates with the INO80 chromatin remodeling complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FIG4 |
YNL325C |
Phosphatidylinositol 3,5-bisphosphate (PtdIns[3,5]P) phosphatase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
MID2 |
YLR332W |
O-glycosylated plasma membrane protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG5 |
YPL227C |
UDP-glucose:dolichyl-phosphate glucosyltransferase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HUB1 |
YNR032C-A |
Ubiquitin-like protein modifier |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ABZ1 |
YNR033W |
Para-aminobenzoate (PABA) synthase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
GAB1 |
YLR459W |
Subunit of the glycosylphosphatidylinositol transamidase complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERI1 |
YPL096C-A |
Endoplasmic reticulum membrane protein that binds and inhibits Ras2p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BST1 |
YFL025C |
GPI inositol deacylase of the endoplasmic reticulum (ER) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ARV1 |
YLR242C |
Cortical ER protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
FPS1 |
YLL043W |
Aquaglyceroporin, plasma membrane channel |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DYN3 |
YMR299C |
Dynein light intermediate chain (LIC) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KRE1 |
YNL322C |
Cell wall glycoprotein involved in beta-glucan assembly |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ALG9 |
YNL219C |
Mannosyltransferase, involved in N-linked glycosylation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CNE1 |
YAL058W |
Calnexin |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IZH1 |
YDR492W |
Membrane protein involved in zinc ion homeostasis |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
COG8 |
YML071C |
Component of the conserved oligomeric Golgi complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TAF9 |
YMR236W |
Subunit (17 kDa) of TFIID and SAGA complexes |
genetic |
2 |
1 |
1 |
Synthetic Lethality, Synthetic Lethality |
TNA1 |
YGR260W |
High affinity nicotinic acid plasma membrane permease |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SYT1 |
YPR095C |
Guanine nucleotide exchange factor (GEF) for Arf proteins |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ACS2 |
YLR153C |
Acetyl-coA synthetase isoform |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
LRG1 |
YDL240W |
GTPase-activating protein (GAP) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CWP2 |
YKL096W-A |
Covalently linked cell wall mannoprotein |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
MSN2 |
YMR037C |
Stress-responsive transcriptional activator |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CTR9 |
YOL145C |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
1 |
1 |
1 |
Positive Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Positive Genetic |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IKI3 |
YLR384C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
EAF5 |
YEL018W |
Non-essential subunit of the NuA4 acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ADH1 |
YOL086C |
Alcohol dehydrogenase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KAP123 |
YER110C |
Karyopherin beta |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTO1 |
YNL260C |
Substrate-specific adaptor protein involved in apo-Rli1p maturation |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRE1 |
YDL074C |
E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP5 |
YOR358W |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MES1 |
YGR264C |
Methionyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAR1 |
YHR089C |
Protein component of the H/ACA snoRNP pseudouridylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP7 |
YKR024C |
Putative ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK21 |
YDR060W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM20 |
YOL076W |
Non-catalytic subunit of the NatB N-terminal acetyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DED1 |
YOR204W |
ATP-dependent DEAD-box RNA helicase with strand-annealing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIS3 |
YOL021C |
Exosome core complex catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP9 |
YMR033W |
Component of both the SWI/SNF and RSC chromatin remodeling complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAP95 |
YLR347C |
Karyopherin beta |
genetic |
1 |
1 |
1 |
Positive Genetic |
CFT2 |
YLR115W |
Subunit of the mRNA cleavage and polyadenlylation factor (CPF) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC39 |
YCR093W |
Subunit of the CCR4-NOT1 core complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BMS1 |
YPL217C |
GTPase required for ribosomal subunit synthesis and rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
APL6 |
YGR261C |
Beta3-like subunit of the yeast AP-3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC40 |
YBR234C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
ASC1 |
YMR116C |
G-protein beta subunit and guanine dissociation inhibitor for Gpa2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
CAP1 |
YKL007W |
Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CAF130 |
YGR134W |
Subunit of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP11 |
YNL315C |
Molecular chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC36 |
YDL165W |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
BNI1 |
YNL271C |
Formin |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC55 |
YGL190C |
Regulatory subunit B of protein phosphatase 2A (PP2A) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX6 |
YHR051W |
Subunit VI of cytochrome c oxidase (Complex IV) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYS4 |
YGR155W |
Cystathionine beta-synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP1 |
YOL149W |
Subunit of the Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DCP2 |
YNL118C |
Catalytic subunit of Dcp1p-Dcp2p decapping enzyme complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DNA2 |
YHR164C |
ATP-dependent 5'-flap endonuclease and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
EAF3 |
YPR023C |
Component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FRS1 |
YLR060W |
Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FKS1 |
YLR342W |
Catalytic subunit of 1,3-beta-D-glucan synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLO3 |
YER122C |
ADP-ribosylation factor GTPase activating protein (ARF GAP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESP1 |
YGR098C |
Separase/separin, a caspase-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
AEP1 |
YMR064W |
Protein required for expression of the mitochondrial OLI1 gene |
genetic |
1 |
1 |
1 |
Positive Genetic |
ACK1 |
YDL203C |
Protein that functions in the cell wall integrity pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLU1 |
YMR012W |
Subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KRR1 |
YCL059C |
Nucleolar protein required for rRNA synthesis and ribosomal assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB1 |
YMR296C |
Component of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM2 |
YBL026W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM6 |
YGL201C |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED11 |
YMR112C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED2 |
YDL005C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD3 |
YCL014W |
Guanine nucleotide exchange factor (GEF) for Cdc42p |
genetic |
1 |
1 |
1 |
Positive Genetic |
HTZ1 |
YOL012C |
Histone variant H2AZ |
genetic |
1 |
1 |
1 |
Positive Genetic |
KCC4 |
YCL024W |
Protein kinase of the bud neck involved in the septin checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP8 |
YOR141C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFG2 |
YLR397C |
ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST3 |
YIL009C-A |
Component of the telomerase holoenzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESF2 |
YNR054C |
Essential nucleolar protein involved in pre-18S rRNA processing |
genetic |
1 |
1 |
1 |
Negative Genetic |
ILV1 |
YER086W |
Threonine deaminase, catalyzes first step in isoleucine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
FYV8 |
YGR196C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED8 |
YBR193C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN11 |
YJL183W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL4B |
YDR012W |
Ribosomal 60S subunit protein L4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
physical |
1 |
1 |
1 |
Co-purification |
NAB2 |
YGL122C |
Nuclear polyadenylated RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP14 |
YDL148C |
Nucleolar protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSB1 |
YDL229W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAM6 |
YDL077C |
Guanine nucleotide exchange factor for the GTPase Gtr1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TOM1 |
YDR457W |
E3 ubiquitin ligase of the hect-domain class |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PSG1 |
YKL077W |
Protein that promotes the transport and maturation of Pma1 with Exp1 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MPS3 |
YJL019W |
Nuclear envelope protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAC6 |
YDR129C |
Fimbrin, actin-bundling protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAF1 |
YBR279W |
Component of the Paf1p complex involved in transcription elongation |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC25 |
YKL144C |
RNA polymerase III subunit C25 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF14 |
YPL129W |
Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP30 |
YMR263W |
Component of Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB2 |
YHR041C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PGD1 |
YGL025C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SQS1 |
YNL224C |
Protein that stimulates the ATPase and helicase activities of Prp43p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD6 |
YGL058W |
Ubiquitin-conjugating enzyme (E2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFG2 |
YGR005C |
TFIIF (Transcription Factor II) middle subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNG2 |
YHR090C |
Subunit of NuA4, an essential histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAF13 |
YML098W |
TFIID subunit (19 kDa) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NGG1 |
YDR176W |
Subunit of chromatin modifying histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RXT3 |
YDL076C |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTA1 |
YAL043C |
Subunit of holo-CPF |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWD2 |
YKL018W |
Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGO1 |
YOR073W |
Component of the spindle checkpoint |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS64 |
YDR200C |
Protein required for cytoplasm to vacuole targeting of proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT3 |
YDR392W |
Subunit of the SAGA and SAGA-like transcriptional regulatory complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RKM2 |
YDR198C |
Ribosomal protein lysine methyltransferase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MRC1 |
YCL061C |
S-phase checkpoint protein required for DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB1 |
YDR311W |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RED1 |
YLR263W |
Protein component of the synaptonemal complex axial elements |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGF29 |
YCL010C |
Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT21 |
YMR179W |
Protein with a role in transcriptional silencing |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS29 |
YHR012W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMS1 |
YNL082W |
ATP-binding protein required for mismatch repair |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MSN5 |
YDR335W |
Karyopherin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RAD27 |
YKL113C |
5' to 3' exonuclease, 5' flap endonuclease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SSN8 |
YNL025C |
Cyclin-like component of RNA polymerase II holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAN3 |
YKL025C |
Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NAM7 |
YMR080C |
ATP-dependent RNA helicase of the SFI superfamily |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SMY1 |
YKL079W |
Kinesin-like myosin passenger-protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STE50 |
YCL032W |
Adaptor protein for various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTC3 |
YBL056W |
Type 2C protein phosphatase (PP2C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPY1 |
YBR129C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMP1 |
YBR182C |
MADS-box transcription factor involved in osmotic stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAT4 |
YCR008W |
Ser/Thr protein kinase involved in salt tolerance, nutrient response |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRK1 |
YDL079C |
Glycogen synthase kinase 3 (GSK-3) homolog |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPD1 |
YDL235C |
Osmotic stress-responsive phosphorelay intermediate sensor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPH3 |
YDR075W |
Catalytic subunit of protein phosphatase PP4 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI5 |
YDR146C |
Transcription factor that recruits Mediator and Swi/Snf complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
PLM2 |
YDR501W |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
PFK1 |
YGR240C |
Alpha subunit of heterooctameric phosphofructokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOS4 |
YLR183C |
Putative transcription factor, contains Forkhead Associated domain |
genetic |
1 |
1 |
1 |
Positive Genetic |
PPZ1 |
YML016C |
Serine/threonine protein phosphatase Z, isoform of Ppz2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NRM1 |
YNR009W |
Transcriptional co-repressor of MBF-regulated gene expression |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCH1 |
YGR203W |
Phosphatase with sequence similarity to Mih1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
STE20 |
YHL007C |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAP1 |
YML007W |
Basic leucine zipper (bZIP) transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSG5 |
YNL053W |
Dual-specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA1 |
YNL099C |
Putative protein tyrosine phosphatase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TEP1 |
YNL128W |
PTEN homolog with no demonstrated inositol lipid phosphatase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRA1 |
YHR099W |
Subunit of SAGA and NuA4 histone acetyltransferase complexes |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
TSC13 |
YDL015C |
Enoyl reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUG1 |
YER006W |
GTPase that associates with nuclear 60S pre-ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAM7 |
YGL212W |
Vacuolar SNARE protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC27 |
YGL137W |
Essential beta'-coat protein of the COPI coatomer |
genetic |
1 |
1 |
1 |
Negative Genetic |
UPF3 |
YGR072W |
Component of the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMD2 |
YHR077C |
Protein involved in the nonsense-mediated mRNA decay (NMD) pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM1 |
YIL105C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWI3 |
YJL176C |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
URA8 |
YJR103W |
Minor CTP synthase isozyme (see also URA7) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SDH1 |
YKL148C |
Flavoprotein subunit of succinate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJU3 |
YKL094W |
Monoglyceride lipase (MGL) that hydrolyzes fatty acid ethyl esters |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSN4 |
YKL062W |
Stress-responsive transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
NFU1 |
YKL040C |
Protein involved in Fe-S cluster transfer to mitochondrial clients |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKR018C |
YKR018C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTH1 |
YKR042W |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
POB3 |
YML069W |
Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS1B |
YML063W |
Ribosomal protein of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIN4 |
YNL236W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOM70 |
YNL121C |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RHO2 |
YNL090W |
Non-essential small GTPase of the Rho/Rac family of Ras-like proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA21 |
YGR105W |
Integral membrane protein required for V-ATPase function |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
VOA1 |
YGR106C |
ER protein that functions in assembly of the V0 sector of V-ATPase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NRD1 |
YNL251C |
RNA-binding subunit of Nrd1 complex |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
NPL3 |
YDR432W |
RNA-binding protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PDR1 |
YGL013C |
Transcription factor that regulates the pleiotropic drug response |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
PFY1 |
YOR122C |
Profilin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
TRS20 |
YBR254C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Positive Genetic |
PMI40 |
YER003C |
Mannose-6-phosphate isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
TOM20 |
YGR082W |
Component of the TOM (translocase of outer membrane) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMD2 |
YLR275W |
Core Sm protein Sm D2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP39 |
YML046W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP24 |
YMR268C |
Splicing factor that reanneals snRNPs during spliceosome recycling |
genetic |
1 |
1 |
1 |
Positive Genetic |
PGA2 |
YNL149C |
Essential protein required for maturation of Gas1p and Pho8p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPO7 |
YAL009W |
Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme |
genetic |
1 |
1 |
1 |
Positive Genetic |
PIN4 |
YBL051C |
Protein involved in G2/M phase progression and response to DNA damage |
genetic |
1 |
1 |
1 |
Positive Genetic |
UBP13 |
YBL067C |
Ubiquitin-specific protease that cleaves Ub-protein fusions |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
RIM15 |
YFL033C |
Protein kinase involved in cell proliferation in response to nutrients |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP2A |
YOL039W |
Ribosomal protein P2 alpha |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRM4 |
YPL156C |
Pheromone-regulated protein proposed to be involved in mating |
genetic |
1 |
1 |
1 |
Positive Genetic |
PXP1 |
YEL020C |
Peroxisomal matrix protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
POX1 |
YGL205W |
Fatty-acyl coenzyme A oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YGL235W |
YGL235W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
XKS1 |
YGR194C |
Xylulokinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
PET130 |
YJL023C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMT1 |
YJL147C |
Translational repressor of the mitochondrial ATP6/8 mRNA |
genetic |
1 |
1 |
1 |
Positive Genetic |
QCR8 |
YJL166W |
Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Positive Genetic |
SAG1 |
YJR004C |
Alpha-agglutinin of alpha-cells |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSM7 |
YJR113C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
PUT1 |
YLR142W |
Proline oxidase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEI1 |
YLR404W |
Seipin involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMA2 |
YML066C |
Meiosis-specific prospore membrane protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YMR030W-A |
YMR030W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
RCO1 |
YMR075W |
Essential component of the Rpd3S histone deacetylase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ZWF1 |
YNL241C |
Glucose-6-phosphate dehydrogenase (G6PD) |
genetic |
1 |
1 |
1 |
Positive Genetic |
MON2 |
YNL297C |
Protein with a role in endocytosis and vacuole integrity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SUV3 |
YPL029W |
ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YPL039W |
YPL039W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
MRN1 |
YPL184C |
RNA-binding protein that may be involved in translational regulation |
genetic |
1 |
1 |
1 |
Positive Genetic |
NTO1 |
YPR031W |
Subunit of the NuA3 histone acetyltransferase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RER2 |
YBR002C |
Forms the dehydrodolichyl diphosphate synthase (DDS) complex with NUS1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC3 |
YBR058C-A |
Protein that stimulates the activity of serine palmitoyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRB6 |
YBR253W |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDI1 |
YCL043C |
Protein disulfide isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC31 |
YDL195W |
Component of the Sec13p-Sec31p complex of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
TLG1 |
YDR468C |
Essential t-SNARE that mediates fusion of vesicles with the late Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
POL5 |
YEL055C |
Protein involved in 60S assembly and pre-40S AFs recycling |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE1 |
YER012W |
Beta 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUP3 |
YER094C |
Beta 3 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPB4 |
YFL002C |
Putative ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSC8 |
YFR037C |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET2 |
YFR051C |
Delta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STT3 |
YGL022W |
Catalytic subunit of the oligosaccharyltransferase complex of the ER l |
genetic |
1 |
1 |
1 |
Negative Genetic |
NBP35 |
YGL091C |
Essential cytoplasmic iron-sulfur cluster binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRM1 |
YGL097W |
Nucleotide exchange factor for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSA1 |
YGL111W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC15 |
YGL233W |
Essential 113 kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP18 |
YGR006W |
Splicing factor and component of snRNP U5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP8 |
YGR128C |
Nucleolar protein required for export of tRNAs from the nucleus |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKI6 |
YGR195W |
Exosome non-catalytic core component |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZPR1 |
YGR211W |
Essential protein with two zinc fingers |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN1 |
YHR027C |
Non-ATPase base subunit of the 19S RP of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
QNS1 |
YHR074W |
Glutamine-dependent NAD(+) synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIX1 |
YHR197W |
Component of the Rix1 complex and possibly pre-replicative complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLN1 |
YIL147C |
Transmembrane histidine phosphotransfer kinase and osmosensor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFA3 |
YJL173C |
Subunit of heterotrimeric Replication Protein A (RPA) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE1 |
YLR007W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NMT1 |
YLR195C |
N-myristoyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP13 |
YLR222C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP21 |
YLR409C |
Subunit of U3-containing 90S preribosome and SSU processome complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEN1 |
YLR430W |
ATP-dependent 5' to 3' RNA/DNA and DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROT1 |
YMR200W |
Molecular chaperone involved in protein folding in ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RNT1 |
YMR239C |
Nuclear dsRNA-specific ribonuclease (RNase III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF11 |
YMR260C |
Translation initiation factor eIF1A |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP1 |
YMR309C |
eIF3c subunit of the eukaryotic translation initiation factor 3 (eIF3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIA1 |
YNL163C |
Cytoplasmic GTPase/eEF2-like factor involved in ribosomal biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAR1 |
YNL240C |
Subunit of the cytosolic iron-sulfur (FeS) protein assembly machinery |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP2 |
YNR011C |
RNA-dependent DExD/H-box ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MVD1 |
YNR043W |
Mevalonate pyrophosphate decarboxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG2 |
YNR053C |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRE6 |
YOL038W |
Alpha 4 subunit of the 20S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
TPT1 |
YOL102C |
tRNA 2'-phosphotransferase that catalyzes final step in tRNA splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT5 |
YOR117W |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN8 |
YOR261C |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
YTM1 |
YOR272W |
Ribosomal assembly factor and 66S pre-ribosomal particle constituent |
genetic |
1 |
1 |
1 |
Negative Genetic |
RET3 |
YPL010W |
Zeta subunit of the coatomer complex (COPI) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC16 |
YPL085W |
COPII vesicle coat protein required for ER transport vesicle budding |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOG1 |
YPL093W |
Putative GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFB2 |
YPL122C |
Subunit of TFIIH and nucleotide excision repair factor 3 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP53 |
YPL146C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP72 |
YPL210C |
Core component of the signal recognition particle (SRP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RDS3 |
YPR094W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRD1 |
YPR112C |
Essential conserved small ribosomal subunit (40s) synthesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT2 |
YAL023C |
Protein O-mannosyltransferase of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBL081W |
YBL081W |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN2 |
YBR015C |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEF2 |
YBR118W |
Translational elongation factor EF-1 alpha |
genetic |
1 |
1 |
1 |
Negative Genetic |
TOS1 |
YBR162C |
Covalently-bound cell wall protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YSY6 |
YBR162W-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS54 |
YDR027C |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TVP23 |
YDR084C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHP10 |
YDL002C |
Non-essential INO80 chromatin remodeling complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
QRI7 |
YDL104C |
Protein involved in threonylcarbamoyl adenosine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL35A |
YDL191W |
Ribosomal 60S subunit protein L35A |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST4 |
YDL232W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRS85 |
YDR108W |
Component of transport protein particle (TRAPP) complex III |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC7 |
YDR389W |
GTPase activating protein (GAP) for Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
URC2 |
YDR520C |
Putative Zn(II)2Cys6 motif containing transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE10 |
YGL228W |
Protein involved in outer spore wall assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIM1 |
YIL123W |
Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SYS1 |
YJL004C |
Integral membrane protein of the Golgi |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS21B |
YJL136C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS55 |
YJR044C |
Late endosomal protein involved in late endosome to vacuole transport |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS38 |
YLR360W |
Part of a Vps34p phosphatidylinositol 3-kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSP2 |
YML017W |
Asn rich cytoplasmic protein that contains RGG motifs |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB6 |
YML117W |
Putative RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM9 |
YMR063W |
Plasma membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS16A |
YMR143W |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIM13 |
YMR154C |
Calpain-like cysteine protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR027C |
YPR027C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR063C |
YPR063C |
ER-localized protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS4 |
YPR173C |
AAA-ATPase involved in multivesicular body (MVB) protein sorting |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS52 |
YDR484W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC8 |
YEL013W |
Vacuole-specific Myo2p receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA3 |
YEL027W |
Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TCA17 |
YEL048C |
Component of transport protein particle (TRAPP) complex II |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA8 |
YEL051W |
Subunit D of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPR6 |
YER115C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YER134C |
YER134C |
Magnesium-dependent acid phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTR1 |
YER139C |
Dual specificity protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGL188C-A |
YGL188C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RMR1 |
YGL250W |
Protein required for meiotic recombination and gene conversion |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEF1 |
YGR058W |
Penta-EF-hand protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR122W |
YGR122W |
Protein that may be involved in pH regulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR161W-C |
YGR161W-C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YGR174W-A |
YGR174W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEL1 |
YHR035W |
Activator of Sar1p GTPase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP10 |
YHR072W-A |
Subunit of box H/ACA snoRNP complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
OSH3 |
YHR073W |
Member of an oxysterol-binding protein family |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
POG1 |
YIL122W |
DNA-binding transcriptional activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL40A |
YIL148W |
Ubiquitin-ribosomal 60S subunit protein L40A fusion protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIR016W |
YIR016W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YJL077W-B |
YJL077W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTC1 |
YJL123C |
Protein of unknown function that may interact with ribosomes |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIF2 |
YJL138C |
Translation initiation factor eIF4A |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT4 |
YJR143C |
Protein O-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSA1 |
YML028W |
Thioredoxin peroxidase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
STE6 |
YKL209C |
Plasma membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
TRP3 |
YKL211C |
Indole-3-glycerol-phosphate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU16 |
YKL224C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS51 |
YKR020W |
Component of the GARP (Golgi-associated retrograde protein) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLL066W-B |
YLL066W-B |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR264C-A |
YLR264C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS25B |
YLR333C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
YLR419W |
YLR419W |
Putative helicase with limited sequence similarity to human Rb protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
OST6 |
YML019W |
Subunit of the oligosaccharyltransferase complex of the ER lumen |
genetic |
1 |
1 |
1 |
Negative Genetic |
MOT3 |
YMR070W |
Transcriptional repressor, activator |
genetic |
1 |
1 |
1 |
Negative Genetic |
VBA1 |
YMR088C |
Permease of basic amino acids in the vacuolar membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
MYO5 |
YMR109W |
One of two type I myosin motors |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHH3 |
YMR118C |
Putative mitochondrial inner membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIS1 |
YNL078W |
Protein involved in axial bud site selection |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX17 |
YNL214W |
Membrane peroxin of the peroxisomal importomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPA49 |
YNL248C |
RNA polymerase I subunit A49 |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL320W |
YNL320W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPP6 |
YNR024W |
Nuclear exosome-associated RNA binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZRG17 |
YNR039C |
Endoplasmic reticulum zinc transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PFA4 |
YOL003C |
Palmitoyltransferase with autoacylation activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI20 |
YOL055C |
Trifunctional enzyme of thiamine biosynthesis, degradation and salvage |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS68 |
YOL129W |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOL164W-A |
YOL164W-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR012W |
YOR012W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHE4 |
YOR035C |
Protein containing a UCS (UNC-45/CRO1/SHE4) domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSB1 |
YOR049C |
Sphingoid long-chain base (LCB) efflux transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS21 |
YOR089C |
Endosomal Rab family GTPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPC54 |
YOR177C |
Component of the meiotic outer plaque |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR186W |
YOR186W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RUD3 |
YOR216C |
Golgi matrix protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YOR292C |
YOR292C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SVL3 |
YPL032C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RGL1 |
YPL066W |
Regulator of Rho1p signaling, cofactor of Tus1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
REC8 |
YPR007C |
Meiosis-specific component of the sister chromatid cohesion complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VMA13 |
YPR036W |
Subunit H of the V1 peripheral membrane domain of V-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB4 |
YLR212C |
Gamma-tubulin |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
genetic |
1 |
1 |
1 |
Negative Genetic |
INP52 |
YNL106C |
Polyphosphatidylinositol phosphatase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
HFI1 |
YPL254W |
Adaptor protein required for structural integrity of the SAGA complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG9 |
YDL149W |
Transmembrane protein involved in forming Cvt and autophagic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTE1 |
YAL024C |
Protein similar to GDP/GTP exchange factors |
genetic |
1 |
1 |
1 |
Positive Genetic |
GLN1 |
YPR035W |
Glutamine synthetase (GS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEK2 |
YBL032W |
RNA binding protein involved in asymmetric localization of ASH1 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
FES1 |
YBR101C |
Hsp70 (Ssa1p) nucleotide exchange factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRZ1 |
YNL027W |
Transcription factor, activates transcription of stress response genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADR1 |
YDR216W |
Carbon source-responsive zinc-finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADH2 |
YMR303C |
Glucose-repressible alcohol dehydrogenase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
HYP2 |
YEL034W |
Translation elongation factor eIF-5A |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADO1 |
YJR105W |
Adenosine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ASA1 |
YPR085C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAC3 |
YBR085W |
Mitochondrial inner membrane ADP/ATP translocator |
genetic |
1 |
1 |
1 |
Positive Genetic |
DMA2 |
YNL116W |
Ubiquitin-protein ligase (E3) |
genetic |
1 |
1 |
1 |
Positive Genetic |
HIR3 |
YJR140C |
Subunit of the HIR complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
GSF2 |
YML048W |
Endoplasmic reticulum (ER) localized integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
APM3 |
YBR288C |
Mu3-like subunit of the clathrin associated protein complex (AP-3) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
LCP5 |
YER127W |
Essential protein involved in maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ESL2 |
YKR096W |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT5 |
YJR064W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLN1 |
YMR199W |
G1 cyclin involved in regulation of the cell cycle |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ECM10 |
YEL030W |
Heat shock protein of the Hsp70 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG27 |
YLR100W |
3-keto sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
GID8 |
YMR135C |
Subunit of GID Complex, binds strongly to central component Vid30p |
genetic |
1 |
1 |
1 |
Positive Genetic |
APE1 |
YKL103C |
Vacuolar aminopeptidase yscI |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG7 |
YHR171W |
Autophagy-related protein and dual specificity member of the E1 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
FAR10 |
YLR238W |
Protein involved in recovery from arrest in response to pheromone |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSL7 |
YBR133C |
Protein arginine N-methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LTP1 |
YPR073C |
Protein phosphotyrosine phosphatase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
EST1 |
YLR233C |
TLC1 RNA-associated factor involved in telomere length regulation |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CDC4 |
YFL009W |
F-box protein required for both the G1/S and G2/M phase transitions |
genetic |
1 |
1 |
1 |
Negative Genetic |
DNL4 |
YOR005C |
DNA ligase required for nonhomologous end-joining (NHEJ) |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRI1 |
YNL308C |
Essential nucleolar protein required for 40S ribosome biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAS1 |
YKR063C |
Endonuclease involved in pre-rRNA processing at both ends of ITS2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
HHO1 |
YPL127C |
Histone H1, linker histone with roles in meiosis and sporulation |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTF4 |
YPR135W |
Chromatin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DPB11 |
YJL090C |
DNA replication initiation protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC123 |
YLR215C |
Assembly factor for the eIF2 translation initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKK2 |
YPL140C |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
BEM4 |
YPL161C |
Protein involved in establishment of cell polarity and bud emergence |
genetic |
1 |
1 |
1 |
Negative Genetic |
KSS1 |
YGR040W |
Mitogen-activated protein kinase (MAPK) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCK2 |
YER167W |
Serine/threonine-rich protein involved in PKC1 signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Positive Genetic |
KIN28 |
YDL108W |
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG4 |
YNL223W |
Conserved cysteine protease required for autophagy |
genetic |
1 |
1 |
1 |
Negative Genetic |
FPK1 |
YNR047W |
Ser/Thr protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CIK1 |
YMR198W |
Kinesin-associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAK2 |
YFL053W |
Dihydroxyacetone kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HAP3 |
YBL021C |
Subunit of the Hap2p/3p/4p/5p CCAAT-binding complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
FKH2 |
YNL068C |
Forkhead family transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIG1 |
YGL035C |
Transcription factor involved in glucose repression |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDH3 |
YDL078C |
Peroxisomal malate dehydrogenase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
FMP48 |
YGR052W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAD2 |
YKR083C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG1 |
YGL180W |
Protein serine/threonine kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GTR1 |
YML121W |
Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPK1 |
YDR315C |
Inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LPP1 |
YDR503C |
Lipid phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST7 |
YGR057C |
Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCN4 |
YEL009C |
bZIP transcriptional activator of amino acid biosynthetic genes |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GNP1 |
YDR508C |
Broad specificity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAK1 |
YFL029C |
Cyclin-dependent kinase-activating kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ5 |
YML110C |
2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ESL1 |
YIL151C |
hEST1A/B (SMG5/6)-like protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPN2 |
YOR262W |
Putative GTPase with a specific role in RNA pol II and polIII biogenes |
genetic |
1 |
1 |
1 |
Negative Genetic |
LAA2 |
YBL010C |
Clathrin adaptor (adaptin) accessory protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GMH1 |
YKR030W |
Golgi membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
COG7 |
YGL005C |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GRC3 |
YLL035W |
Polynucleotide kinase present on rDNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
1 |
1 |
1 |
Positive Genetic |
BFR1 |
YOR198C |
Component of mRNP complexes associated with polyribosomes |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BUD4 |
YJR092W |
Anillin-like protein involved in bud-site selection |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLC1 |
YGR167W |
Clathrin light chain |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
HXK2 |
YGL253W |
Hexokinase isoenzyme 2 |
genetic |
1 |
1 |
1 |
Positive Genetic |
KAR3 |
YPR141C |
Minus-end-directed microtubule motor |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM3 |
YEL032W |
Protein involved in DNA replication |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG2 |
YNL242W |
Peripheral membrane protein required for autophagic vesicle formation |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLN3 |
YER040W |
Transcriptional activator in nitrogen catabolite repression system |
genetic |
1 |
1 |
1 |
Positive Genetic |
EMC1 |
YCL045C |
Member of conserved endoplasmic reticulum membrane complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCS1 |
YMR038C |
Copper chaperone for superoxide dismutase Sod1p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
MCM7 |
YBR202W |
Component of the Mcm2-7 hexameric helicase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG25 |
YGR060W |
C-4 methyl sterol oxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCH1 |
YMR237W |
Member of the ChAPs family (Chs5p-Arf1p-binding proteins) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HKR1 |
YDR420W |
Mucin family member that functions as an osmosensor in the HOG pathway |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GFD2 |
YCL036W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKK1 |
YOR231W |
MAPKK involved in the protein kinase C signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATP10 |
YLR393W |
Assembly factor for the F0 sector of mitochondrial F1F0 ATP synthase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ENT2 |
YLR206W |
Epsin-like protein required for endocytosis and actin patch assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
CPR7 |
YJR032W |
Peptidyl-prolyl cis-trans isomerase (cyclophilin) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GAT1 |
YFL021W |
Transcriptional activator of nitrogen catabolite repression genes |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX17 |
YLL009C |
Copper metallochaperone that transfers copper to Sco1p and Cox11p |
genetic |
1 |
1 |
1 |
Positive Genetic |
AUR1 |
YKL004W |
Phosphatidylinositol:ceramide phosphoinositol transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BSD2 |
YBR290W |
Heavy metal ion homeostasis protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MID1 |
YNL291C |
Stretch-activated Ca2+-permeable cation channel |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ATM1 |
YMR301C |
Mitochondrial inner membrane ATP-binding cassette (ABC) transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
INN1 |
YNL152W |
Essential protein that associates with contractile actomyosin ring |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM31 |
YHR194W |
Mitochondrial protein that may have a role in phospholipid metabolism |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
GEF1 |
YJR040W |
Voltage-gated chloride channel |
genetic |
1 |
1 |
1 |
Negative Genetic |
BCH2 |
YKR027W |
Member of the ChAPs (Chs5p-Arf1p-binding proteins) family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MMS1 |
YPR164W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Negative Genetic |
GDA1 |
YEL042W |
Guanosine diphosphatase located in the Golgi |
genetic |
1 |
1 |
1 |
Positive Genetic |
GPI2 |
YPL076W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG3 |
YBL082C |
Dolichol-P-Man dependent alpha(1-3) mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ADE16 |
YLR028C |
Enzyme of 'de novo' purine biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRL1 |
YHR036W |
Essential nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB5 |
YLR260W |
Minor sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUL3 |
YGR003W |
Ubiquitin-protein ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEF2 |
YJL102W |
Mitochondrial elongation factor involved in translational elongation |
genetic |
1 |
1 |
1 |
Positive Genetic |
MBR1 |
YKL093W |
Protein involved in mitochondrial functions and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
IRC25 |
YLR021W |
Component of a heterodimeric Poc4p-Irc25p chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
JID1 |
YPR061C |
Probable Hsp40p co-chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
CWH41 |
YGL027C |
Processing alpha glucosidase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
COA3 |
YJL062W-A |
Mitochondrial protein required for cytochrome c oxidase assembly |
genetic |
1 |
1 |
1 |
Positive Genetic |
GAA1 |
YLR088W |
Subunit of the GPI:protein transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ISR1 |
YPR106W |
Predicted protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
IDI1 |
YPL117C |
Isopentenyl diphosphate:dimethylallyl diphosphate isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT3 |
YKL146W |
Vacuolar transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB1 |
YDR531W |
Pantothenate kinase, ATP:D-pantothenate 4'-phosphotransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUP1 |
YGL084C |
Plasma membrane protein involved in remodeling GPI anchors |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM7 |
YLR443W |
Putative integral membrane protein with a role in calcium uptake |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX10 |
YPL172C |
Heme A:farnesyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CYT1 |
YOR065W |
Cytochrome c1 |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG13 |
YGL047W |
Catalytic component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIS1 |
YDR096W |
Histone demethylase and transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CHS2 |
YBR038W |
Chitin synthase II |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
AST2 |
YER101C |
Lipid raft associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG4 |
YGL012W |
C-24(28) sterol reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG14 |
YBR070C |
Component of UDP-GlcNAc transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEP1 |
YGR121C |
Ammonium permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX23 |
YHR116W |
Protein that functions in mitochondrial copper homeostasis |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG12 |
YNR030W |
Alpha-1,6-mannosyltransferase localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BIG1 |
YHR101C |
Integral membrane protein of the endoplasmic reticulum |
genetic |
1 |
1 |
1 |
Negative Genetic |
HPT1 |
YDR399W |
Dimeric hypoxanthine-guanine phosphoribosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI14 |
YJR013W |
Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC8 |
YJR057W |
Nucleoside monophosphate and nucleoside diphosphate kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUR1 |
YPR158W |
Sorting factor, central regulator of spatial protein quality control |
genetic |
1 |
1 |
1 |
Negative Genetic |
FIT2 |
YOR382W |
Mannoprotein that is incorporated into the cell wall |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI18 |
YBR004C |
Functional ortholog of human PIG-V |
genetic |
1 |
1 |
1 |
Negative Genetic |
DIE2 |
YGR227W |
Dolichyl-phosphoglucose-dependent alpha-1,2-glucosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
LCB4 |
YOR171C |
Sphingoid long-chain base kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
physical |
1 |
1 |
1 |
PCA |
ERD1 |
YDR414C |
Predicted membrane protein required for lumenal ER protein retention |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCP1 |
YOR228C |
Mitochondrial protein of unknown function involved in lipid homeostas |
genetic |
1 |
1 |
1 |
Negative Genetic |
LMO1 |
YLL007C |
Homolog of mammalian ELMO (Engulfment and celL MOtility) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI15 |
YNL038W |
Protein involved in the synthesis of GlcNAc-PI |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG12 |
YMR208W |
Mevalonate kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMP2 |
YMR035W |
Catalytic subunit of mitochondrial inner membrane peptidase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
HXT14 |
YNL318C |
Protein with similarity to hexose transporter family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTR86 |
YCR054C |
Essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
DFR1 |
YOR236W |
Dihydrofolate reductase involved in tetrahydrofolate biosynthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
AGP1 |
YCL025C |
Broad-specificity, low-affinity amino acid permease |
genetic |
1 |
1 |
1 |
Negative Genetic |
DGK1 |
YOR311C |
Diacylglycerol kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALK2 |
YBL009W |
Atypical protein kinase |
genetic |
1 |
1 |
1 |
Positive Genetic |
HEM4 |
YOR278W |
Uroporphyrinogen III synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRE7 |
YOL152W |
Putative ferric reductase with similarity to Fre2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
APQ12 |
YIL040W |
Nuclear envelope/ER integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAX4 |
YGR036C |
Dolichyl pyrophosphate (Dol-P-P) phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ANS1 |
YHR126C |
Putative GPI protein |
genetic |
1 |
1 |
1 |
Negative Genetic |