Standard name Systematic name Name description Description
MTC1 YJL123C Protein of unknown function that may interact with ribosomes Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); mtc1 is synthetically lethal with cdc13-1
Visualize the interactome of MTC1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
M 180

CYCLoPs localization & abundance

WT1 WT2 WT3
Cort. Patches 0.050 0.124 0.226
Cytoplasm 0.333 0.724 0.314
Endosome 0.063 NaN NaN
Golgi 0.314 0.105 0.401
Mito 0.340 NaN 0.226
Vac/Vac Memb 0.126 NaN NaN
ER NaN 0.181 0.182

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
MTC1 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
GET3 YDL100C Guanine nucleotide exchange factor for Gpa1p genetic 9 2 6 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG5 YNL051W Component of the conserved oligomeric Golgi complex genetic 9 2 5 Negative Genetic, Negative Genetic, Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 8 3 6 Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG6 YNL041C Component of the conserved oligomeric Golgi complex genetic 8 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GET1 YGL020C Subunit of the GET complex genetic 7 3 5 Negative Genetic, Synthetic Lethality, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
COG8 YML071C Component of the conserved oligomeric Golgi complex genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 7 1 5 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TRS85 YDR108W Component of transport protein particle (TRAPP) complex III genetic 7 2 4 Negative Genetic, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC22 YLR268W R-SNARE protein genetic 6 2 4 Negative Genetic, Phenotypic Suppression, Phenotypic Suppression, Negative Genetic, Negative Genetic, Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 6 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SEC66 YBR171W Non-essential subunit of Sec63 complex genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SPF1 YEL031W P-type ATPase, ion transporter of the ER membrane genetic 5 1 4 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 4 2 4 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic
COG3 YER157W Essential component of the conserved oligomeric Golgi complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG2 YGR120C Essential component of the conserved oligomeric Golgi complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
ERG25 YGR060W C-4 methyl sterol oxidase genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
COY1 YKL179C Golgi membrane protein with similarity to mammalian CASP genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
USO1 YDL058W Essential protein involved in vesicle-mediated ER to Golgi transport genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 4 3 2 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic, Negative Genetic
TRM1 YDR120C tRNA methyltransferase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
SLA1 YBL007C Cytoskeletal protein binding protein genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
KIN82 YCR091W Putative serine/threonine protein kinase genetic 3 1 3 Negative Genetic, Negative Genetic, Negative Genetic
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 3 2 2 Phenotypic Suppression, Phenotypic Suppression, Negative Genetic
MDY2 YOL111C Protein involved in inserting tail-anchored proteins into ER membranes genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic
SUM1 YDR310C Transcriptional repressor that regulates middle-sporulation genes genetic 3 2 2 Phenotypic Enhancement, Phenotypic Enhancement, Positive Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
YPT1 YFL038C Rab family GTPase genetic 3 2 2 Negative Genetic, Positive Genetic, Negative Genetic
ACT1 YFL039C Actin, structural protein in cytoskeleton genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
CPR7 YJR032W Peptidyl-prolyl cis-trans isomerase (cyclophilin) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
TRS23 YDR246W Core component of transport protein particle (TRAPP) complexes I-III genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 2 2 2 Synthetic Lethality, Synthetic Growth Defect
APC11 YDL008W Catalytic core subunit, Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 2 2 2 Negative Genetic, Positive Genetic
SLT2 YHR030C Serine/threonine MAP kinase genetic 2 2 2 Dosage Growth Defect, Negative Genetic
COP1 YDL145C Alpha subunit of COPI vesicle coatomer complex genetic 2 1 2 Negative Genetic, Negative Genetic
CMD1 YBR109C Calmodulin genetic 2 1 2 Negative Genetic, Negative Genetic
HOM3 YER052C Aspartate kinase (L-aspartate 4-P-transferase) genetic 2 1 2 Negative Genetic, Negative Genetic
GDH2 YDL215C NAD(+)-dependent glutamate dehydrogenase genetic 2 1 2 Negative Genetic, Negative Genetic
IES2 YNL215W Protein that associates with the INO80 chromatin remodeling complex genetic 2 1 2 Negative Genetic, Negative Genetic
HOC1 YJR075W Alpha-1,6-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
GAB1 YLR459W Subunit of the glycosylphosphatidylinositol transamidase complex genetic 2 1 2 Positive Genetic, Positive Genetic
BTS1 YPL069C Geranylgeranyl diphosphate synthase (GGPPS) genetic 2 1 2 Negative Genetic, Negative Genetic
OYE2 YHR179W Conserved NADPH oxidoreductase containing flavin mononucleotide (FMN) genetic 2 1 2 Negative Genetic, Negative Genetic
NUP133 YKR082W Subunit of Nup84p subcomplex of nuclear pore complex (NPC) genetic 2 1 2 Negative Genetic, Negative Genetic
RPS0B YLR048W Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SHE4 YOR035C Protein containing a UCS (UNC-45/CRO1/SHE4) domain genetic 2 1 2 Negative Genetic, Negative Genetic
VPS74 YDR372C Golgi PI4K effector, PtdIns4P sensor, and retention receptor genetic 2 1 2 Negative Genetic, Negative Genetic
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 2 1 2 Negative Genetic, Negative Genetic
PAN1 YIR006C Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p genetic 2 1 2 Negative Genetic, Negative Genetic
SSL1 YLR005W Subunit of the core form of RNA polymerase transcription factor TFIIH genetic 2 1 2 Negative Genetic, Negative Genetic
SED5 YLR026C cis-Golgi t-SNARE syntaxin genetic 2 1 2 Negative Genetic, Negative Genetic
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 2 1 2 Negative Genetic, Negative Genetic
RCE1 YMR274C Type II CAAX prenyl protease genetic 2 1 2 Negative Genetic, Negative Genetic
TGS1 YPL157W Trimethyl guanosine synthase, conserved nucleolar methyl transferase genetic 2 1 2 Negative Genetic, Negative Genetic
GPX2 YBR244W Phospholipid hydroperoxide glutathione peroxidase genetic 2 1 2 Negative Genetic, Negative Genetic
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 2 1 2 Negative Genetic, Negative Genetic
RTF1 YGL244W Subunit of RNAPII-associated chromatin remodeling Paf1 complex genetic 2 2 1 Positive Genetic, Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 2 2 1 Positive Genetic, Negative Genetic
SRV2 YNL138W CAP (cyclase-associated protein) genetic 2 2 1 Positive Genetic, Negative Genetic
GOT1 YMR292W Homodimeric protein that is packaged into COPII vesicles genetic 2 2 1 Positive Genetic, Negative Genetic
KRE1 YNL322C Cell wall glycoprotein involved in beta-glucan assembly genetic 2 2 1 Positive Genetic, Negative Genetic
GWT1 YJL091C Protein involved in the inositol acylation of GlcN-PI genetic 2 1 1 Negative Genetic, Negative Genetic
HDA1 YNL021W Catalytic subunit of class II HDA1 histone deacetylase complex genetic 2 1 1 Dosage Lethality, Dosage Lethality
BET5 YML077W Core component of transport protein particle (TRAPP) complexes I-III genetic 2 1 1 Negative Genetic, Negative Genetic
GET4 YOR164C Protein involved in inserting tail-anchored proteins into ER membranes genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
BOS1 YLR078C v-SNARE (vesicle specific SNAP receptor) genetic 2 1 1 Negative Genetic, Negative Genetic
ATG8 YBL078C Ub-like protein genetic 2 1 1 Negative Genetic, Negative Genetic
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes genetic 2 1 1 Dosage Lethality, Dosage Lethality
VRG4 YGL225W Golgi GDP-mannose transporter genetic 2 1 1 Negative Genetic, Negative Genetic
NUS1 YDL193W Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 genetic 2 1 1 Positive Genetic, Positive Genetic
TLG2 YOL018C Syntaxin-like t-SNARE genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
YHR078W YHR078W High osmolarity-regulated gene of unknown function genetic 2 1 1 Phenotypic Enhancement, Phenotypic Enhancement
RUD3 YOR216C Golgi matrix protein genetic 2 1 1 Positive Genetic, Positive Genetic
DOS2 YDR068W Protein of unknown function genetic 2 1 1 Negative Genetic, Negative Genetic
BIG1 YHR101C Integral membrane protein of the endoplasmic reticulum genetic 2 1 1 Negative Genetic, Negative Genetic
GPI8 YDR331W Catalytic subunit of the ER membrane GPI transamidase complex genetic 2 1 1 Negative Genetic, Negative Genetic
CAX4 YGR036C Dolichyl pyrophosphate (Dol-P-P) phosphatase genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
BRR2 YER172C RNA-dependent ATPase RNA helicase (DEIH box) genetic 1 1 1 Synthetic Growth Defect
LSM6 YDR378C Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
CBC2 YPL178W Small subunit of the heterodimeric cap binding complex with Sto1p genetic 1 1 1 Negative Genetic
ARX1 YDR101C Nuclear export factor for the ribosomal pre-60S subunit genetic 1 1 1 Negative Genetic
CFT2 YLR115W Subunit of the mRNA cleavage and polyadenlylation factor (CPF) genetic 1 1 1 Negative Genetic
ARO1 YDR127W Pentafunctional arom protein genetic 1 1 1 Positive Genetic
BEM2 YER155C Rho GTPase activating protein (RhoGAP) genetic 1 1 1 Negative Genetic
CAP1 YKL007W Alpha subunit of the capping protein heterodimer (Cap1p and Cap2p) genetic 1 1 1 Negative Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
CTF18 YMR078C Subunit of a complex with Ctf8p genetic 1 1 1 Negative Genetic
EDE1 YBL047C Scaffold protein involved in the formation of early endocytic sites genetic 1 1 1 Negative Genetic
ELP2 YGR200C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
GDI1 YER136W GDP dissociation inhibitor genetic 1 1 1 Negative Genetic
HHF1 YBR009C Histone H4 physical 1 1 1 Affinity Capture-MS
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
HHF2 YNL030W Histone H4 physical 1 1 1 Affinity Capture-MS
DPB4 YDR121W Subunit of DNA pol epsilon and of ISW2 chromatin accessibility complex genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase genetic 1 1 1 Negative Genetic
LAS17 YOR181W Actin assembly factor genetic 1 1 1 Negative Genetic
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MRP49 YKL167C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ATG3 YNR007C E2-like enzyme genetic 1 1 1 Negative Genetic
GIN4 YDR507C Protein kinase involved in bud growth and assembly of the septin ring genetic 1 1 1 Dosage Growth Defect
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
IES1 YFL013C Subunit of the INO80 chromatin remodeling complex genetic 1 1 1 Negative Genetic
FAS2 YPL231W Alpha subunit of fatty acid synthetase genetic 1 1 1 Negative Genetic
GIM3 YNL153C Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
HSP82 YPL240C Hsp90 chaperone physical 1 1 1 Affinity Capture-MS
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Positive Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Negative Genetic
FYV8 YGR196C Protein of unknown function genetic 1 1 1 Negative Genetic
CTI6 YPL181W Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
CCT6 YDR188W Subunit of the cytosolic chaperonin Cct ring complex genetic 1 1 1 Negative Genetic
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles genetic 1 1 1 Negative Genetic
MCM2 YBL023C Protein involved in DNA replication genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Negative Genetic
BOI1 YBL085W Protein involved in polar growth, functionally redundant with Boi2p genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Lethality
ABP1 YCR088W Actin-binding protein of the cortical actin cytoskeleton genetic 1 1 1 Negative Genetic
CSR2 YPR030W Nuclear ubiquitin protein ligase binding protein genetic 1 1 1 Negative Genetic
IDH1 YNL037C Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Negative Genetic
CNB1 YKL190W Calcineurin B genetic 1 1 1 Negative Genetic
FUM1 YPL262W Fumarase genetic 1 1 1 Negative Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
MRS6 YOR370C Rab escort protein genetic 1 1 1 Negative Genetic
EST1 YLR233C TLC1 RNA-associated factor involved in telomere length regulation genetic 1 1 1 Synthetic Growth Defect
ACS1 YAL054C Acetyl-coA synthetase isoform genetic 1 1 1 Negative Genetic
HHT1 YBR010W Histone H3 physical 1 1 1 Affinity Capture-MS
MRE11 YMR224C Nuclease subunit of the MRX complex with Rad50p and Xrs2p genetic 1 1 1 Negative Genetic
BEM4 YPL161C Protein involved in establishment of cell polarity and bud emergence genetic 1 1 1 Negative Genetic
BCK2 YER167W Serine/threonine-rich protein involved in PKC1 signaling pathway genetic 1 1 1 Negative Genetic
HMG2 YLR450W HMG-CoA reductase genetic 1 1 1 Positive Genetic
MEH1 YKR007W Subunit of the EGO/GSE complex genetic 1 1 1 Negative Genetic
CBR1 YIL043C Cytochrome b reductase and NADH-dependent reductase for Dph3p genetic 1 1 1 Negative Genetic
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase genetic 1 1 1 Negative Genetic
CDC7 YDL017W S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
ATG1 YGL180W Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
ATP20 YPR020W Subunit g of the mitochondrial F1F0 ATP synthase genetic 1 1 1 Positive Genetic
FMN1 YDR236C Riboflavin kinase, produces riboflavin monophosphate (FMN) genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
GTR1 YML121W Subunit of a TORC1-stimulating GTPase and the EGO/GSE complex genetic 1 1 1 Negative Genetic
IRE1 YHR079C Serine-threonine kinase and endoribonuclease genetic 1 1 1 Positive Genetic
LPP1 YDR503C Lipid phosphate phosphatase genetic 1 1 1 Negative Genetic
MSN5 YDR335W Karyopherin genetic 1 1 1 Negative Genetic
HSP10 YOR020C Mitochondrial matrix co-chaperonin genetic 1 1 1 Negative Genetic
CLG1 YGL215W Cyclin-like protein that interacts with Pho85p genetic 1 1 1 Positive Genetic
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
KTI12 YKL110C Protein that plays a role in modification of tRNA wobble nucleosides genetic 1 1 1 Negative Genetic
ELP6 YMR312W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
COG4 YPR105C Essential component of the conserved oligomeric Golgi complex genetic 1 1 1 Negative Genetic
GMH1 YKR030W Golgi membrane protein of unknown function genetic 1 1 1 Negative Genetic
ELP3 YPL086C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 1 1 1 Negative Genetic
CHL1 YPL008W Probable DNA helicase genetic 1 1 1 Negative Genetic
BRE5 YNR051C Ubiquitin protease cofactor genetic 1 1 1 Negative Genetic
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein physical 1 1 1 Affinity Capture-MS
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
CLB5 YPR120C B-type cyclin involved in DNA replication during S phase genetic 1 1 1 Negative Genetic
CLC1 YGR167W Clathrin light chain genetic 1 1 1 Negative Genetic
COX18 YGR062C Protein required for membrane insertion of C-terminus of Cox2p genetic 1 1 1 Negative Genetic
CTF8 YHR191C Subunit of a complex with Ctf18p genetic 1 1 1 Negative Genetic
DBF4 YDR052C Regulatory subunit of Cdc7p-Dbf4p kinase complex genetic 1 1 1 Negative Genetic
BET1 YIL004C Type II membrane protein required for vesicular transport genetic 1 1 1 Negative Genetic
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Positive Genetic
CST9 YLR394W SUMO E3 ligase genetic 1 1 1 Positive Genetic
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
CSG2 YBR036C Endoplasmic reticulum membrane protein genetic 1 1 1 Negative Genetic
INP53 YOR109W Polyphosphatidylinositol phosphatase genetic 1 1 1 Positive Genetic
MSB4 YOL112W GTPase-activating protein of the Ras superfamily genetic 1 1 1 Negative Genetic
HHT2 YNL031C Histone H3 physical 1 1 1 Affinity Capture-MS
ERV14 YGL054C COPII-coated vesicle protein genetic 1 1 1 Positive Genetic
EAF7 YNL136W Subunit of the NuA4 histone acetyltransferase complex physical 1 1 1 Affinity Capture-MS
BUG1 YDL099W Cis-golgi localized protein involved in ER to Golgi transport genetic 1 1 1 Negative Genetic
BSC6 YOL137W Protein of unknown function with 8 putative transmembrane segments genetic 1 1 1 Negative Genetic
GDA1 YEL042W Guanosine diphosphatase located in the Golgi genetic 1 1 1 Negative Genetic
KEX1 YGL203C Cell death protease essential for hypochlorite-induced apoptosis genetic 1 1 1 Positive Genetic
IFA38 YBR159W Microsomal beta-keto-reductase physical 1 1 1 Affinity Capture-MS
CPR5 YDR304C Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the ER genetic 1 1 1 Negative Genetic
BPH1 YCR032W Protein homologous to Chediak-Higashi syndrome and Beige proteins genetic 1 1 1 Negative Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex genetic 1 1 1 Negative Genetic
COQ11 YLR290C Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes genetic 1 1 1 Negative Genetic
SPT15 YER148W TATA-binding protein (TBP) physical 1 1 1 Affinity Capture-MS
ZEO1 YOL109W Peripheral membrane protein of the plasma membrane physical 1 1 1 Affinity Capture-MS
RPD3 YNL330C Histone deacetylase, component of both the Rpd3S and Rpd3L complexes physical 1 1 1 Affinity Capture-MS
PTK2 YJR059W Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
YGK3 YOL128C Protein kinase related to mammalian GSK-3 glycogen synthase kinases physical 1 1 1 Affinity Capture-MS
OPY2 YPR075C Integral membrane protein that acts as a membrane anchor for Ste50p physical 1 1 1 Two-hybrid
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
PUF4 YGL014W Member of the PUF protein family physical 1 1 1 Affinity Capture-RNA
RPS9A YPL081W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS12 YOR369C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS15 YOL040C Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS27A YKL156W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
RPS3 YNL178W Protein component of the small (40S) ribosomal subunit physical 1 1 1 Affinity Capture-MS
SKT5 YBL061C Activator of Chs3p (chitin synthase III) during vegetative growth genetic 1 1 1 Negative Genetic
POP4 YBR257W Subunit of both RNase MRP and nuclear RNase P genetic 1 1 1 Negative Genetic
RPC53 YDL150W RNA polymerase III subunit C53 genetic 1 1 1 Negative Genetic
SAC3 YDR159W mRNA export factor genetic 1 1 1 Negative Genetic
TRS31 YDR472W Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex genetic 1 1 1 Negative Genetic
YTA7 YGR270W Chromatin-binding ATPase that regulates histone gene expression genetic 1 1 1 Negative Genetic
ROT2 YBR229C Glucosidase II catalytic subunit genetic 1 1 1 Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 1 1 1 Negative Genetic
YKT6 YKL196C Vesicle membrane protein (v-SNARE) with acyltransferase activity genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Negative Genetic
POL1 YNL102W Catalytic subunit of the DNA polymerase I alpha-primase complex genetic 1 1 1 Synthetic Growth Defect
POL2 YNL262W Catalytic subunit of DNA polymerase (II) epsilon genetic 1 1 1 Synthetic Growth Defect
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Positive Genetic
RSM24 YDR175C Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Positive Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Positive Genetic
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Positive Genetic
SLY1 YDR189W Hydrophilic protein involved in ER/Golgi vesicle trafficking genetic 1 1 1 Negative Genetic
TLG1 YDR468C Essential t-SNARE that mediates fusion of vesicles with the late Golgi genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
UTR5 YEL035C Protein of unknown function genetic 1 1 1 Negative Genetic
RRP4 YHR069C Exosome non-catalytic core component genetic 1 1 1 Negative Genetic
PRP2 YNR011C RNA-dependent DExD/H-box ATPase genetic 1 1 1 Negative Genetic
YTM1 YOR272W Ribosomal assembly factor and 66S pre-ribosomal particle constituent genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
RSP5 YER125W NEDD4 family E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
RPL4A YBR031W Ribosomal 60S subunit protein L4A genetic 1 1 1 Negative Genetic
TVS1 YCR061W Protein of unknown function genetic 1 1 1 Negative Genetic
RAD18 YCR066W E3 ubiquitin ligase genetic 1 1 1 Negative Genetic
RAM1 YDL090C Beta subunit of the CAAX farnesyltransferase (FTase) genetic 1 1 1 Negative Genetic
PFU1 YDR306C F-box protein that regulates pheromone-dependent morphogenesis genetic 1 1 1 Negative Genetic
YGL114W YGL114W Putative protein of unknown function genetic 1 1 1 Negative Genetic
TIM21 YGR033C Nonessential component of the TIM23 complex genetic 1 1 1 Negative Genetic
PIH1 YHR034C Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) genetic 1 1 1 Negative Genetic
YHK8 YHR048W Presumed antiporter of the major facilitator superfamily genetic 1 1 1 Negative Genetic
SEC28 YIL076W Epsilon-COP subunit of the coatomer genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
YER084W YER084W Protein of unknown function genetic 1 1 1 Negative Genetic
UPS1 YLR193C Phosphatidic acid transfer protein genetic 1 1 1 Negative Genetic
YPT7 YML001W Rab family GTPase genetic 1 1 1 Negative Genetic
PUB1 YNL016W Poly (A)+ RNA-binding protein genetic 1 1 1 Negative Genetic
PMA2 YPL036W Plasma membrane H+-ATPase genetic 1 1 1 Negative Genetic
SRO7 YPR032W Effector of Rab GTPase Sec4p genetic 1 1 1 Negative Genetic
POM33 YLL023C Transmembrane nucleoporin genetic 1 1 1 Negative Genetic
SKI2 YLR398C Ski complex component and putative RNA helicase genetic 1 1 1 Negative Genetic
RSF1 YMR030W Protein required for respiratory growth genetic 1 1 1 Negative Genetic
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
YNL165W YNL165W Putative protein of unknown function genetic 1 1 1 Negative Genetic
SLA2 YNL243W Adaptor protein that links actin to clathrin and endocytosis genetic 1 1 1 Negative Genetic
TOF1 YNL273W Subunit of a replication-pausing checkpoint complex genetic 1 1 1 Negative Genetic
NBA1 YOL070C Protein involved in axial bud site selection genetic 1 1 1 Negative Genetic
NCR1 YPL006W Vacuolar membrane protein involved with Npc2p in sterol trafficking genetic 1 1 1 Negative Genetic
YNG2 YHR090C Subunit of NuA4, an essential histone acetyltransferase complex genetic 1 1 1 Positive Genetic
SEC7 YDR170C Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors genetic 1 1 1 Negative Genetic
NTO1 YPR031W Subunit of the NuA3 histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer genetic 1 1 1 Positive Genetic
TFC3 YAL001C Subunit of RNA polymerase III transcription initiation factor complex genetic 1 1 1 Negative Genetic
SEC17 YBL050W Alpha-SNAP cochaperone genetic 1 1 1 Negative Genetic
RAD57 YDR004W Protein that stimulates strand exchange genetic 1 1 1 Negative Genetic
SOK1 YDR006C Protein of unknown function genetic 1 1 1 Negative Genetic
RRP8 YDR083W Nucleolar S-adenosylmethionine-dependent rRNA methyltransferase genetic 1 1 1 Negative Genetic
SWR1 YDR334W Swi2/Snf2-related ATPase genetic 1 1 1 Positive Genetic
SAC7 YDR389W GTPase activating protein (GAP) for Rho1p genetic 1 1 1 Positive Genetic
RPS24A YER074W Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
SWI4 YER111C DNA binding component of the SBF complex (Swi4p-Swi6p) genetic 1 1 1 Negative Genetic
RPN12 YFR052W Subunit of the 19S regulatory particle of the 26S proteasome lid genetic 1 1 1 Negative Genetic
MUP1 YGR055W High affinity methionine permease genetic 1 1 1 Negative Genetic
PEX4 YGR133W Peroxisomal ubiquitin conjugating enzyme genetic 1 1 1 Positive Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 1 1 1 Negative Genetic
STB5 YHR178W Transcription factor genetic 1 1 1 Negative Genetic
SAC1 YKL212W Phosphatidylinositol phosphate phosphatase genetic 1 1 1 Positive Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Positive Genetic
RPS30A YLR287C-A Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
VRP1 YLR337C Verprolin, proline-rich actin-associated protein genetic 1 1 1 Negative Genetic
VPS38 YLR360W Part of a Vps34p phosphatidylinositol 3-kinase complex genetic 1 1 1 Positive Genetic
NUP188 YML103C Subunit of the inner ring of the nuclear pore complex (NPC) genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Positive Genetic
PET8 YNL003C S-adenosylmethionine transporter of the mitochondrial inner membrane genetic 1 1 1 Positive Genetic
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone genetic 1 1 1 Negative Genetic
NAB3 YPL190C RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) genetic 1 1 1 Positive Genetic
SRN2 YLR119W Component of the ESCRT-I complex genetic 1 1 1 Negative Genetic
UFE1 YOR075W t-SNARE protein required for retrograde vesicular traffic genetic 1 1 1 Negative Genetic
OAF1 YAL051W Oleate-activated transcription factor genetic 1 1 1 Negative Genetic
PEX22 YAL055W Putative peroxisomal membrane protein genetic 1 1 1 Negative Genetic
NCL1 YBL024W S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 1 1 1 Negative Genetic
SEA4 YBL104C Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
PKC1 YBL105C Protein serine/threonine kinase genetic 1 1 1 Negative Genetic
RXT2 YBR095C Component of the histone deacetylase Rpd3L complex genetic 1 1 1 Negative Genetic
RTC2 YBR147W Putative vacuolar membrane transporter for cationic amino acids genetic 1 1 1 Negative Genetic
PPS1 YBR276C Protein phosphatase genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Negative Genetic
NSE4 YDL105W Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
MTC5 YDR128W Subunit of SEACAT, a subcomplex of the SEA complex genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
TCP1 YDR212W Alpha subunit of chaperonin-containing T-complex genetic 1 1 1 Negative Genetic
RPB7 YDR404C RNA polymerase II subunit B16 genetic 1 1 1 Negative Genetic
PPM1 YDR435C Carboxyl methyltransferase genetic 1 1 1 Negative Genetic
PPN1 YDR452W Dual endo- and exopolyphosphatase with a role in phosphate metabolism genetic 1 1 1 Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 1 1 1 Negative Genetic
TSC11 YER093C Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) genetic 1 1 1 Negative Genetic
RPL2A YFR031C-A Ribosomal 60S subunit protein L2A genetic 1 1 1 Negative Genetic
NBP35 YGL091C Essential cytoplasmic iron-sulfur cluster binding protein genetic 1 1 1 Negative Genetic
SLD3 YGL113W Protein involved in the initiation of DNA replication genetic 1 1 1 Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 1 1 1 Negative Genetic
TAN1 YGL232W Putative tRNA acetyltransferase genetic 1 1 1 Negative Genetic
PEF1 YGR058W Penta-EF-hand protein genetic 1 1 1 Negative Genetic
UPF3 YGR072W Component of the nonsense-mediated mRNA decay (NMD) pathway genetic 1 1 1 Negative Genetic
ZPR1 YGR211W Essential protein with two zinc fingers genetic 1 1 1 Negative Genetic
OPI1 YHL020C Transcriptional regulator of a variety of genes genetic 1 1 1 Negative Genetic
RRM3 YHR031C DNA helicase involved in rDNA replication and Ty1 transposition genetic 1 1 1 Negative Genetic
UBA4 YHR111W E1-like protein that activates Urm1p before urmylation genetic 1 1 1 Negative Genetic
URM1 YIL008W Ubiquitin-like protein involved in thiolation of cytoplasmic tRNAs genetic 1 1 1 Negative Genetic
SDS3 YIL084C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
RHO3 YIL118W Non-essential small GTPase of the Rho/Rac family of Ras-like proteins genetic 1 1 1 Negative Genetic
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
TOR1 YJR066W PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
RAD27 YKL113C 5' to 3' exonuclease, 5' flap endonuclease genetic 1 1 1 Negative Genetic
TIF1 YKR059W Translation initiation factor eIF4A genetic 1 1 1 Negative Genetic
PXL1 YKR090W Protein that localizes to sites of polarized growth genetic 1 1 1 Negative Genetic
RPL40B YKR094C Ubiquitin-ribosomal 60S subunit protein L40B fusion protein genetic 1 1 1 Negative Genetic
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex genetic 1 1 1 Negative Genetic
NSE5 YML023C Component of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
POB3 YML069W Subunit of the heterodimeric FACT complex (Spt16p-Pob3p) genetic 1 1 1 Negative Genetic
YML108W YML108W Protein of unknown function genetic 1 1 1 Negative Genetic
TAF4 YMR005W TFIID subunit (48 kDa) genetic 1 1 1 Negative Genetic
PDS5 YMR076C Cohesion maintenance factor genetic 1 1 1 Negative Genetic
NAM7 YMR080C ATP-dependent RNA helicase of the SFI superfamily genetic 1 1 1 Negative Genetic
SAP30 YMR263W Component of Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
ZDS1 YMR273C Protein with a role in regulating Swe1p-dependent polarized growth genetic 1 1 1 Negative Genetic
NCS2 YNL119W Protein required for uridine thiolation of Lys(UUU) and Glu(UUC) tRNAs genetic 1 1 1 Negative Genetic
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Negative Genetic
STI1 YOR027W Evolutionarily-conserved Hsp90 cochaperone genetic 1 1 1 Negative Genetic
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
TUM1 YOR251C Rhodanese domain sulfur transferase genetic 1 1 1 Negative Genetic
RBL2 YOR265W Protein involved in microtubule morphogenesis genetic 1 1 1 Negative Genetic
SSE1 YPL106C ATPase component of heat shock protein Hsp90 chaperone complex genetic 1 1 1 Negative Genetic
RRD2 YPL152W Peptidyl-prolyl cis/trans-isomerase genetic 1 1 1 Negative Genetic
PUS1 YPL212C tRNA:pseudouridine synthase genetic 1 1 1 Negative Genetic
TMA7 YLR262C-A Protein of unknown function that associates with ribosomes genetic 1 1 1 Negative Genetic
YPR078C YPR078C Putative protein of unknown function genetic 1 1 1 Negative Genetic
SSH1 YBR283C Subunit of the Ssh1 translocon complex genetic 1 1 1 Negative Genetic
SEC59 YMR013C Dolichol kinase genetic 1 1 1 Negative Genetic
MET10 YFR030W Subunit alpha of assimilatory sulfite reductase physical 1 1 1 Affinity Capture-MS
IAI11 YBL059W Putative mitochondrial protein of unknown function genetic 1 1 1 Negative Genetic
CYB5 YNL111C Cytochrome b5 genetic 1 1 1 Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic
DGA1 YOR245C Diacylglycerol acyltransferase genetic 1 1 1 Negative Genetic
EMC4 YGL231C Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
ERG24 YNL280C C-14 sterol reductase genetic 1 1 1 Negative Genetic
ALG6 YOR002W ER-luminal alpha 1,3 glucosyltransferase genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex genetic 1 1 1 Negative Genetic
ENA5 YDR038C Protein with similarity to P-type ATPase sodium pumps genetic 1 1 1 Negative Genetic
CEM1 YER061C Mitochondrial beta-keto-acyl synthase genetic 1 1 1 Negative Genetic
CHO2 YGR157W Phosphatidylethanolamine methyltransferase (PEMT) genetic 1 1 1 Negative Genetic
GPI13 YLL031C ER membrane localized phosphoryltransferase genetic 1 1 1 Negative Genetic
CCW12 YLR110C Cell wall mannoprotein genetic 1 1 1 Negative Genetic
DLD1 YDL174C Major mitochondrial D-lactate dehydrogenase genetic 1 1 1 Negative Genetic
DPL1 YDR294C Dihydrosphingosine phosphate lyase genetic 1 1 1 Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 1 1 1 Negative Genetic
MDM35 YKL053C-A Mitochondrial intermembrane space protein genetic 1 1 1 Negative Genetic
GPI10 YGL142C Integral membrane protein involved in GPI anchor synthesis genetic 1 1 1 Negative Genetic
CMC2 YBL059C-A Protein involved in respiratory chain complex assembly or maintenance genetic 1 1 1 Negative Genetic
EMC3 YKL207W Member of conserved ER transmembrane complex genetic 1 1 1 Negative Genetic
DGK1 YOR311C Diacylglycerol kinase genetic 1 1 1 Negative Genetic
CNE1 YAL058W Calnexin genetic 1 1 1 Negative Genetic
MGR2 YPL098C Subunit of the TIM23 translocase complex genetic 1 1 1 Negative Genetic
LST4 YKL176C Subunit of the Lst4p-Lst7p GTPase activating protein complex for Gtr2p genetic 1 1 1 Negative Genetic
ATP23 YNR020C Putative metalloprotease of the mitochondrial inner membrane genetic 1 1 1 Negative Genetic
ICE2 YIL090W Integral ER membrane protein with type-III transmembrane domains genetic 1 1 1 Positive Genetic
KRE5 YOR336W Protein required for beta-1,6 glucan biosynthesis genetic 1 1 1 Negative Genetic