Standard name Systematic name Name description Description
VTC1 YER072W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex Regulatory subunit of the vacuolar transporter chaperone (VTC) complex; VTC complex is involved in membrane trafficking, vacuolar polyphosphate accumulation, microautophagy and non-autophagic vacuolar fusion; also has mRNA binding activity; protein abundance increases in response to DNA replication stress
Visualize the interactome of VTC1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
G1(P) 23

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.457 0.579 0.506
ER 0.139 0.219 0.296
Vac/Vac Memb 0.459 0.230 0.235

GFP localization & abundance

GFP localization GFP abundance
ER 12100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
VTC1 5 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
CHK1 YBR274W Serine/threonine kinase and DNA damage checkpoint effector genetic 4 1 2 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
VTC3 YPL019C Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 2 2 2 Affinity Capture-MS, Affinity Capture-Western
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
TGL2 YDR058C Triacylglycerol lipase that is localized to the mitochondria genetic 2 1 2 Negative Genetic, Negative Genetic
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 2 1 2 Positive Genetic, Positive Genetic
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
RPS21B YJL136C Protein component of the small (40S) ribosomal subunit genetic 2 1 2 Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 2 2 1 Negative Genetic, Positive Genetic
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth physical 2 2 1 Two-hybrid, Affinity Capture-Western
GLC7 YER133W Type 1 S/T protein phosphatase (PP1) catalytic subunit genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
HEK2 YBL032W RNA binding protein involved in asymmetric localization of ASH1 mRNA genetic 2 1 1 Negative Genetic, Negative Genetic
GET2 YER083C Subunit of the GET complex genetic 2 1 1 Phenotypic Suppression, Phenotypic Suppression
PDI1 YCL043C Protein disulfide isomerase genetic 2 1 1 Synthetic Lethality, Synthetic Lethality
IPK1 YDR315C Inositol 1,3,4,5,6-pentakisphosphate 2-kinase genetic 2 1 1 Negative Genetic, Negative Genetic
RMD1 YDL001W Cytoplasmic protein required for sporulation genetic 2 1 1 Negative Genetic, Negative Genetic
ELP4 YPL101W Subunit of hexameric RecA-like ATPase Elp456 Elongator subcomplex genetic 2 1 1 Negative Genetic, Negative Genetic
VTC5 YDR089W Novel subunit of the vacuolar transporter chaperone complex physical 2 1 1 Affinity Capture-Western, Affinity Capture-Western
YAR029W YAR029W Member of DUP240 gene family but contains no transmembrane domains genetic 2 1 1 Negative Genetic, Negative Genetic
DSF2 YBR007C Deletion suppressor of mpt5 mutation genetic 2 1 1 Negative Genetic, Negative Genetic
MSS1 YMR023C Mitochondrial protein genetic 2 1 1 Positive Genetic, Positive Genetic
DFM1 YDR411C Endoplasmic reticulum (ER) localized protein genetic 2 1 1 Negative Genetic, Negative Genetic
SFT2 YBL102W Tetra-spanning membrane protein found mostly in the late Golgi genetic 2 1 1 Negative Genetic, Negative Genetic
ERD1 YDR414C Predicted membrane protein required for lumenal ER protein retention genetic 2 1 1 Negative Genetic, Negative Genetic
VPS9 YML097C Guanine nucleotide exchange factor (GEF) and ubiquitin receptor genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CBF1 YJR060W Basic helix-loop-helix (bHLH) protein regulation 1 1 1 chromatin immunoprecipitation-chip evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
GCR1 YPL075W Transcriptional activator of genes involved in glycolysis regulation 1 1 1 DNA to cDNA expression microarray evidence
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
RAP1 YNL216W Essential DNA-binding transcription regulator that binds many loci regulation 1 1 1 DNA to cDNA expression microarray evidence
HSF1 YGL073W Trimeric heat shock transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 1 1 1 DNA to cDNA expression microarray evidence
MED4 YOR174W Subunit of the RNA polymerase II mediator complex regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 DNA to cDNA expression microarray evidence
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
ARP4 YJL081C Nuclear actin-related protein involved in chromatin remodeling genetic 1 1 1 Negative Genetic
UTP13 YLR222C Nucleolar protein genetic 1 1 1 Negative Genetic
MES1 YGR264C Methionyl-tRNA synthetase physical 1 1 1 Affinity Capture-RNA
DBP7 YKR024C Putative ATP-dependent RNA helicase of the DEAD-box family genetic 1 1 1 Negative Genetic
PAT1 YCR077C Deadenylation-dependent mRNA-decapping factor physical 1 1 1 Affinity Capture-RNA
DED1 YOR204W ATP-dependent DEAD-box RNA helicase with strand-annealing activity physical 1 1 1 Affinity Capture-MS
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Rescue
PRE2 YPR103W Beta 5 subunit of the 20S proteasome genetic 1 1 1 Negative Genetic
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CDC24 YAL041W Guanine nucleotide exchange factor (GEF) for Cdc42p genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CKS1 YBR135W Cyclin-dependent protein kinase regulatory subunit and adaptor genetic 1 1 1 Negative Genetic
MAL12 YGR292W Maltase (alpha-D-glucosidase) genetic 1 1 1 Negative Genetic
MLH1 YMR167W Protein required for mismatch repair in mitosis and meiosis genetic 1 1 1 Negative Genetic
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MYO2 YOR326W Type V myosin motor involved in actin-based transport of cargos genetic 1 1 1 Negative Genetic
SWH1 YAR042W Protein similar to mammalian oxysterol-binding protein genetic 1 1 1 Negative Genetic
PDB1 YBR221C E1 beta subunit of the pyruvate dehydrogenase (PDH) complex genetic 1 1 1 Negative Genetic
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
LEA1 YPL213W Component of U2 snRNP complex genetic 1 1 1 Negative Genetic
INO4 YOL108C Transcription factor involved in phospholipid synthesis genetic 1 1 1 Negative Genetic
NOP14 YDL148C Nucleolar protein physical 1 1 1 Affinity Capture-MS
RFA1 YAR007C Subunit of heterotrimeric Replication Protein A (RPA) genetic 1 1 1 Negative Genetic
MNN10 YDR245W Subunit of a Golgi mannosyltransferase complex genetic 1 1 1 Negative Genetic
SEC63 YOR254C Essential subunit of Sec63 complex physical 1 1 1 Two-hybrid
SMD1 YGR074W Core Sm protein Sm D1 genetic 1 1 1 Negative Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SEN1 YLR430W ATP-dependent 5' to 3' RNA/DNA and DNA helicase genetic 1 1 1 Negative Genetic
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Positive Genetic
DTD1 YDL219W D-Tyr-tRNA(Tyr) deacylase genetic 1 1 1 Negative Genetic
PUF3 YLL013C Protein of the mitochondrial outer surface physical 1 1 1 Affinity Capture-RNA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-MS
CDC5 YMR001C Polo-like kinase required for mitotic exit physical 1 1 1 Proximity Label-MS
PPQ1 YPL179W Protein phosphatase that regulates the mating response genetic 1 1 1 Negative Genetic
PMA1 YGL008C Plasma membrane P2-type H+-ATPase physical 1 1 1 Affinity Capture-MS
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Positive Genetic
MET30 YIL046W F-box protein containing five copies of the WD40 motif genetic 1 1 1 Negative Genetic
UFD2 YDL190C Ubiquitin (Ub) chain assembly factor (E4) genetic 1 1 1 Negative Genetic
CDC4 YFL009W F-box protein required for both the G1/S and G2/M phase transitions genetic 1 1 1 Negative Genetic
THI21 YPL258C Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase genetic 1 1 1 Negative Genetic
CIN5 YOR028C Basic leucine zipper (bZIP) transcription factor of the yAP-1 family genetic 1 1 1 Negative Genetic
SNF4 YGL115W Activating gamma subunit of the AMP-activated Snf1p kinase complex genetic 1 1 1 Positive Genetic
APL4 YPR029C Gamma-adaptin genetic 1 1 1 Negative Genetic
DCK1 YLR422W Dock family protein (Dedicator Of CytoKinesis), homolog of human DOCK1 genetic 1 1 1 Negative Genetic
DAD1 YDR016C Essential subunit of the Dam1 complex (aka DASH complex) genetic 1 1 1 Negative Genetic
EBS1 YDR206W Protein involved in translation inhibition and nonsense-mediated decay genetic 1 1 1 Negative Genetic
GNA1 YFL017C Glucosamine-6-phosphate acetyltransferase genetic 1 1 1 Negative Genetic
MOB2 YFL034C-B Activator of Cbk1p kinase genetic 1 1 1 Positive Genetic
CSM3 YMR048W Replication fork associated factor genetic 1 1 1 Negative Genetic
RAD4 YER162C Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 genetic 1 1 1 Negative Genetic
AIM18 YHR198C Protein of unknown function genetic 1 1 1 Negative Genetic
ADY3 YDL239C Protein required for spore wall formation genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
SWC5 YBR231C Component of the SWR1 complex genetic 1 1 1 Negative Genetic
SWI6 YLR182W Transcription cofactor genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
KAR3 YPR141C Minus-end-directed microtubule motor genetic 1 1 1 Negative Genetic
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex genetic 1 1 1 Phenotypic Suppression
PHO80 YOL001W Cyclin genetic 1 1 1 Phenotypic Suppression
SEC22 YLR268W R-SNARE protein genetic 1 1 1 Negative Genetic
STU1 YBL034C Microtubule plus-end-tracking non-motor protein genetic 1 1 1 Negative Genetic
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Affinity Capture-Western
KAR2 YJL034W ATPase involved in protein import into the ER genetic 1 1 1 Positive Genetic
GAP1 YKR039W General amino acid permease physical 1 1 1 Affinity Capture-Western
MPT5 YGL178W mRNA-binding protein of the PUF family physical 1 1 1 Affinity Capture-RNA
POL32 YJR043C Third subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
CDC19 YAL038W Pyruvate kinase physical 1 1 1 Affinity Capture-MS
MGA1 YGR249W Protein similar to heat shock transcription factor genetic 1 1 1 Negative Genetic
BSD2 YBR290W Heavy metal ion homeostasis protein genetic 1 1 1 Positive Genetic
SSB2 YNL209W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Co-purification
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p genetic 1 1 1 Negative Genetic
MRC1 YCL061C S-phase checkpoint protein required for DNA replication genetic 1 1 1 Negative Genetic
HCM1 YCR065W Forkhead transcription factor genetic 1 1 1 Negative Genetic
ASF2 YDL197C Anti-silencing protein genetic 1 1 1 Negative Genetic
ERG2 YMR202W C-8 sterol isomerase genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
VTC4 YJL012C Vacuolar membrane polyphosphate polymerase physical 1 1 1 Affinity Capture-MS
VTC2 YFL004W Regulatory subunit of the vacuolar transporter chaperone (VTC) complex physical 1 1 1 Affinity Capture-MS
YPP1 YGR198W Cargo-transport protein involved in endocytosis genetic 1 1 1 Phenotypic Enhancement
YBP1 YBR216C Protein involved in cellular response to oxidative stress genetic 1 1 1 Negative Genetic
YBR284W YBR284W Putative metallo-dependent hydrolase superfamily protein genetic 1 1 1 Negative Genetic
YBR287W YBR287W Protein of unknown function genetic 1 1 1 Negative Genetic
YCR102C YCR102C Putative quinone oxidoreductase genetic 1 1 1 Negative Genetic
WHI4 YDL224C Putative RNA binding protein genetic 1 1 1 Negative Genetic
YGL230C YGL230C Putative protein of unknown function genetic 1 1 1 Negative Genetic
XKS1 YGR194C Xylulokinase genetic 1 1 1 Negative Genetic
YJL163C YJL163C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YGR126W YGR126W Putative protein of unknown function genetic 1 1 1 Positive Genetic
SLF1 YDR515W RNA binding protein that associates with polysomes physical 1 1 1 Affinity Capture-RNA
MTC1 YJL123C Protein of unknown function that may interact with ribosomes genetic 1 1 1 Negative Genetic
BAR1 YIL015W Aspartyl protease secreted to periplasmic space of mating type a cell genetic 1 1 1 Negative Genetic
ETR1 YBR026C 2-enoyl thioester reductase genetic 1 1 1 Negative Genetic
RPP1A YDL081C Ribosomal stalk protein P1 alpha genetic 1 1 1 Negative Genetic
APS1 YLR170C Small subunit of the clathrin-associated adaptor complex AP-1 genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Negative Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
SYF2 YGR129W Member of the NineTeen Complex (NTC) genetic 1 1 1 Negative Genetic
SLM3 YDL033C tRNA-specific 2-thiouridylase genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
NMT1 YLR195C N-myristoyl transferase genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Biochemical Activity
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Negative Genetic
PNT1 YOR266W Mitochondrial integral inner membrane protein genetic 1 1 1 Negative Genetic
GSC2 YGR032W Catalytic subunit of 1,3-beta-glucan synthase genetic 1 1 1 Negative Genetic
RPP1B YDL130W Ribosomal protein P1 beta genetic 1 1 1 Negative Genetic
MDM34 YGL219C Mitochondrial component of the ERMES complex physical 1 1 1 Affinity Capture-MS
RPS16B YDL083C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Positive Genetic
SNQ2 YDR011W Plasma membrane ATP-binding cassette (ABC) transporter physical 1 1 1 PCA
CGR1 YGL029W Protein involved in nucleolar integrity and processing of pre-rRNA genetic 1 1 1 Negative Genetic
VOA1 YGR106C ER protein that functions in assembly of the V0 sector of V-ATPase genetic 1 1 1 Synthetic Growth Defect
ATG15 YCR068W Phospholipase genetic 1 1 1 Negative Genetic
TDH3 YGR192C Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), isozyme 3 physical 1 1 1 Affinity Capture-MS
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
RBK1 YCR036W Ribokinase, phosphorylates ribose to ribose-5-phosphate genetic 1 1 1 Negative Genetic
ATG22 YCL038C Vacuolar integral membrane protein required for efflux of amino acids genetic 1 1 1 Negative Genetic
TNA1 YGR260W High affinity nicotinic acid plasma membrane permease genetic 1 1 1 Negative Genetic
MMM1 YLL006W ER integral membrane protein, ERMES complex subunit physical 1 1 1 Affinity Capture-MS
RSM28 YDR494W Mitochondrial ribosomal protein of the small subunit genetic 1 1 1 Negative Genetic
VMS1 YDR049W Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic