NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
physical |
6 |
3 |
5 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Two-hybrid |
RBA50 |
YDR527W |
Protein involved in transcription |
genetic |
4 |
3 |
2 |
Negative Genetic, Negative Genetic, Dosage Rescue, Synthetic Growth Defect |
ESS1 |
YJR017C |
Peptidylprolyl-cis/trans-isomerase (PPIase) |
genetic |
3 |
2 |
2 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
3 |
2 |
2 |
Synthetic Growth Defect, Negative Genetic, Negative Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
3 |
2 |
1 |
Positive Genetic, Negative Genetic, Negative Genetic |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Lethality |
NPA3 |
YJR072C |
Member of the conserved GPN-loop GTPase family |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Dosage Rescue |
GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
genetic |
2 |
2 |
2 |
Negative Genetic, Dosage Rescue |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CEF1 |
YMR213W |
Essential splicing factor |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CCT6 |
YDR188W |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
2 |
1 |
1 |
Affinity Capture-Western, Affinity Capture-Western |
PSF1 |
YDR013W |
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p) |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
SDS3 |
YIL084C |
Component of the Rpd3L histone deacetylase complex |
genetic |
2 |
1 |
1 |
Positive Genetic, Positive Genetic |
RPB5 |
YBR154C |
RNA polymerase subunit ABC27 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
POP7 |
YBR167C |
Subunit of RNase MRP, nuclear RNase P and telomerase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SNU23 |
YDL098C |
Component of the U4/U6.U5 snRNP complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
TIM22 |
YDL217C |
Essential core component of mitochondrial TIM22 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HEM13 |
YDR044W |
Coproporphyrinogen III oxidase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RPC11 |
YDR045C |
RNA polymerase III subunit C11 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SUP35 |
YDR172W |
Translation termination factor eRF3 |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HSF1 |
YGL073W |
Trimeric heat shock transcription factor |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
MET30 |
YIL046W |
F-box protein containing five copies of the WD40 motif |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SEC22 |
YLR268W |
R-SNARE protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
YHC1 |
YLR298C |
Component of the U1 snRNP complex required for pre-mRNA splicing |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
NSE5 |
YML023C |
Component of the SMC5-SMC6 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VTI1 |
YMR197C |
Protein involved in cis-Golgi membrane traffic |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWC3 |
YAL011W |
Protein of unknown function |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VMS1 |
YDR049W |
Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HOM2 |
YDR158W |
Aspartic beta semi-aldehyde dehydrogenase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SWR1 |
YDR334W |
Swi2/Snf2-related ATPase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
HOS2 |
YGL194C |
Histone deacetylase and subunit of Set3 and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
PBS2 |
YJL128C |
MAP kinase kinase of the HOG signaling pathway |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
ARP6 |
YLR085C |
Actin-related protein that binds nucleosomes |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
GCD10 |
YNL062C |
Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
BET1 |
YIL004C |
Type II membrane protein required for vesicular transport |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
CDC19 |
YAL038W |
Pyruvate kinase |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
IXR1 |
YKL032C |
Transcriptional repressor that regulates hypoxic genes during normoxia |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
RPN4 |
YDL020C |
Transcription factor that stimulates expression of proteasome genes |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
XBP1 |
YIL101C |
Transcriptional repressor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
ABF1 |
YKL112W |
DNA binding protein with possible chromatin-reorganizing activity |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CAD1 |
YDR423C |
AP-1-like basic leucine zipper (bZIP) transcriptional activator |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
CWC25 |
YNL245C |
Splicing factor required for the first step of pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
CKB2 |
YOR039W |
Beta' regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
GCD11 |
YER025W |
Gamma subunit of the translation initiation factor eIF2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Positive Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET2 |
YPR176C |
Beta subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCA1 |
YER168C |
ATP (CTP):tRNA-specific tRNA nucleotidyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCL1 |
YPR025C |
Cyclin partner of the cyclin-dependent kinase (CDK) Kin28p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC11 |
YJR076C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
1 |
1 |
1 |
Negative Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELP2 |
YGR200C |
Subunit of Elongator complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
ENP1 |
YBR247C |
Protein associated with U3 and U14 snoRNAs |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG13 |
YML126C |
3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTO1 |
YCR015C |
Protein required for cold tolerance |
genetic |
1 |
1 |
1 |
Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CWC22 |
YGR278W |
Spliceosome-associated protein that is required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
BET5 |
YML077W |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
CAB5 |
YDR196C |
Subunit of the CoA-Synthesizing Protein Complex (CoA-SPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC13 |
YDL220C |
Single stranded DNA-binding protein found at TG1-3 telomere G-tails |
genetic |
1 |
1 |
1 |
Negative Genetic |
DCS1 |
YLR270W |
Non-essential hydrolase involved in mRNA decapping |
genetic |
1 |
1 |
1 |
Negative Genetic |
GET1 |
YGL020C |
Subunit of the GET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Negative Genetic |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
DUO1 |
YGL061C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
1 |
1 |
1 |
Positive Genetic |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CLG1 |
YGL215W |
Cyclin-like protein that interacts with Pho85p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT5 |
YML010W |
Spt4p/5p (DSIF) transcription elongation factor complex subunit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SBA1 |
YKL117W |
Co-chaperone that binds and regulates Hsp90 family chaperones |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
GPN3 |
YLR243W |
Putative GTPase with a role in biogenesis of RNA pol II and polIII |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSB2 |
YNL209W |
Cytoplasmic ATPase that is a ribosome-associated molecular chaperone |
physical |
1 |
1 |
1 |
Co-purification |
RET1 |
YOR207C |
Second-largest subunit of RNA polymerase III |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
RPC10 |
YHR143W-A |
RNA polymerase subunit ABC10-alpha, found in RNA pol I, II, and III |
genetic |
1 |
1 |
1 |
Dosage Rescue |
RBA50 |
YDR527W |
Protein involved in transcription |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
MLH3 |
YPL164C |
Protein involved in DNA mismatch repair and meiotic recombination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
RPB2 |
YOR151C |
RNA polymerase II second largest subunit B150 |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
RPA190 |
YOR341W |
RNA polymerase I largest subunit A190 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RPO31 |
YOR116C |
RNA polymerase III largest subunit C160 |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
RRN3 |
YKL125W |
Protein required for transcription of rDNA by RNA polymerase I |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IWR1 |
YDL115C |
RNA polymerase II transport factor, conserved from yeast to humans |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
TAF1 |
YGR274C |
TFIID subunit, involved in RNA pol II transcription initiation |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NCB2 |
YDR397C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP22 |
YER013W |
DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPS2 |
YGL123W |
Protein component of the small (40S) subunit |
genetic |
1 |
1 |
1 |
Positive Genetic |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
YJU2 |
YKL095W |
Essential protein required for pre-mRNA splicing |
genetic |
1 |
1 |
1 |
Positive Genetic |
RSC58 |
YLR033W |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPL10 |
YLR075W |
Ribosomal 60S subunit protein L10 |
genetic |
1 |
1 |
1 |
Positive Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPP0 |
YLR340W |
Conserved ribosomal protein P0 of the ribosomal stalk |
genetic |
1 |
1 |
1 |
Positive Genetic |
ORC2 |
YBR060C |
Subunit of the origin recognition complex (ORC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TAF5 |
YBR198C |
Subunit (90 kDa) of TFIID and SAGA complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP28 |
YDR243C |
Pre-mRNA splicing factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
PRP43 |
YGL120C |
RNA helicase in the DEAH-box family |
genetic |
1 |
1 |
1 |
Positive Genetic |
IPA1 |
YJR141W |
Protein implicated in pre-mRNA processing and proteasomal degradation |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP56 |
YLR197W |
Essential evolutionarily-conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Positive Genetic |
NOP2 |
YNL061W |
rRNA m5C methyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
SEC62 |
YPL094C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPN7 |
YPR108W |
Essential non-ATPase regulatory subunit of the 26S proteasome |
genetic |
1 |
1 |
1 |
Positive Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSF1 |
YHR066W |
Constituent of 66S pre-ribosomal particles |
genetic |
1 |
1 |
1 |
Positive Genetic |
IST3 |
YIR005W |
Component of the U2 snRNP |
genetic |
1 |
1 |
1 |
Positive Genetic |
TMA22 |
YJR014W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
OPY2 |
YPR075C |
Integral membrane protein that acts as a membrane anchor for Ste50p |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN2 |
YDR443C |
Subunit of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
MSC1 |
YML128C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
IRC21 |
YMR073C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Positive Genetic |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
1 |
1 |
1 |
Positive Genetic |
SSN3 |
YPL042C |
Component of the RNA polymerase II mediator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
POP5 |
YAL033W |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC1 |
YBR123C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC53 |
YDL150W |
RNA polymerase III subunit C53 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUS1 |
YDL193W |
Forms dehydrodolichyl diphosphate synthase complex with RER2 or SRT1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC1 |
YDR164C |
Sm-like protein involved in docking and fusion of exocytic vesicles |
genetic |
1 |
1 |
1 |
Negative Genetic |
HEM1 |
YDR232W |
5-aminolevulinate synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP42 |
YDR235W |
U1 snRNP protein involved in splicing |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM44 |
YIL022W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAB1 |
YER165W |
Poly(A) binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TUB2 |
YFL037W |
Beta-tubulin |
genetic |
1 |
1 |
1 |
Negative Genetic |
USE1 |
YGL098W |
Essential SNARE protein localized to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Negative Genetic |
GUS1 |
YGL245W |
Glutamyl-tRNA synthetase (GluRS) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHT1 |
YGR065C |
High-affinity plasma membrane H+-biotin (vitamin H) symporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTI1 |
YGR156W |
Essential component of CPF (cleavage and polyadenylation factor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YIP1 |
YGR172C |
Integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPP1 |
YHR062C |
Subunit of both RNase MRP and nuclear RNase P |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC6 |
YIL068C |
Essential 88kDa subunit of the exocyst complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THS1 |
YIL078W |
Threonyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSL5 |
YLR116W |
Component of commitment complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TEM1 |
YML064C |
GTPase involved in initiation of Mitotic Exit Network (MEN) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC19 |
YNL113W |
RNA polymerase subunit AC19 |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAF1 |
YNL124W |
RNA-binding protein required for the assembly of box H/ACA snoRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC31 |
YNL151C |
RNA polymerase III subunit C31 |
genetic |
1 |
1 |
1 |
Negative Genetic |
POP1 |
YNL221C |
Subunit of RNase MRP, nuclear RNase P and telomerase complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSU72 |
YNL222W |
Phosphatase and transcription/RNA-processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
WRS1 |
YOL097C |
Cytoplasmic tryptophanyl-tRNA synthetase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE4 |
YDL105W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSE3 |
YDR288W |
Component of the SMC5-SMC6 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC6 |
YDR362C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSP5 |
YER125W |
NEDD4 family E3 ubiquitin ligase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC4 |
YGR047C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC24 |
YIL109C |
Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC17 |
YJL011C |
RNA polymerase III subunit C17 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM16 |
YJL104W |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SED5 |
YLR026C |
cis-Golgi t-SNARE syntaxin |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC39 |
YLR440C |
Component of the Dsl1p tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LST8 |
YNL006W |
Protein required for the transport of Gap1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM23 |
YNR017W |
Essential component of the TIM23 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIB2 |
YOL066C |
Bifunctional DRAP deaminase tRNA:pseudouridine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRP1 |
YOL123W |
Subunit of cleavage factor I |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGT1 |
YOR057W |
Cochaperone protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TBF1 |
YPL128C |
Telobox-containing general regulatory factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAB3 |
YPL190C |
RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RVB2 |
YPL235W |
ATP-dependent DNA helicase, also known as reptin |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRP4 |
YPR178W |
Splicing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
TFC8 |
YPL007C |
Subunit of RNA polymerase III transcription initiation factor complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
MET8 |
YBR213W |
Bifunctional dehydrogenase and ferrochelatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWC5 |
YBR231C |
Component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGL2 |
YDR058C |
Triacylglycerol lipase that is localized to the mitochondria |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS41 |
YDR080W |
Subunit of the HOPS endocytic tethering complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MKC7 |
YDR144C |
GPI-anchored aspartyl protease |
genetic |
1 |
1 |
1 |
Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
MNN10 |
YDR245W |
Subunit of a Golgi mannosyltransferase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX41 |
YDR425W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS72 |
YDR485C |
Htz1p-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD4 |
YER162C |
Damaged-DNA binding subunit of Nuclear Excision Repair Factor 2 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAU5 |
YFL020C |
Member of the seripauperin multigene family |
genetic |
1 |
1 |
1 |
Negative Genetic |
HXK1 |
YFR053C |
Hexokinase isoenzyme 1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAN2 |
YGL094C |
Catalytic subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRM2 |
YGL136C |
Mitochondrial 2' O-ribose methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM34 |
YGL219C |
Mitochondrial component of the ERMES complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTF1 |
YGL244W |
Subunit of RNAPII-associated chromatin remodeling Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF6 |
YHL025W |
Subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIH1 |
YHR034C |
Component of the conserved R2TP complex (Rvb1-Rvb2-Tah1-Pih1) |
genetic |
1 |
1 |
1 |
Negative Genetic |
STB5 |
YHR178W |
Transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNX4 |
YJL036W |
Sorting nexin |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIR1 |
YJR077C |
Mitochondrial phosphate carrier |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAC1 |
YKL212W |
Phosphatidylinositol phosphate phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SAP190 |
YKR028W |
Protein that forms a complex with the Sit4p protein phosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
ROM2 |
YLR371W |
Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL6B |
YLR448W |
Ribosomal 60S subunit protein L6B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIT1 |
YMR283C |
Initiator methionine 2'-O-ribosyl phosphate transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TDA1 |
YMR291W |
Protein kinase of unknown cellular role |
genetic |
1 |
1 |
1 |
Negative Genetic |
OCA2 |
YNL056W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDJ1 |
YNL064C |
Type I HSP40 co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCK2 |
YNL154C |
Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
THI6 |
YPL214C |
Thiamine-phosphate diphosphorylase and hydroxyethylthiazole kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
NEW1 |
YPL226W |
Translation termination and ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRO7 |
YPR032W |
Effector of Rab GTPase Sec4p |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTB2 |
YBL002W |
Histone H2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIF2 |
YBR103W |
WD40 repeat-containing subunit of Set3C histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEX32 |
YBR168W |
Peroxisomal integral membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR238C |
YBR238C |
Mitochondrial membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIC12 |
YBR262C |
Component of the MICOS complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
LDB16 |
YCL005W |
Protein involved in lipid droplet (LD) assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
HTL1 |
YCR020W-B |
Component of the RSC chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPR1 |
YDL035C |
Plasma membrane G protein coupled receptor (GPCR) |
genetic |
1 |
1 |
1 |
Negative Genetic |
LHP1 |
YDL051W |
RNA binding protein required for maturation of tRNA and U6 snRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAM1 |
YDL090C |
Beta subunit of the CAAX farnesyltransferase (FTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HNT1 |
YDL125C |
Adenosine 5'-monophosphoramidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDL211C |
YDL211C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHS1 |
YDL225W |
Component of the septin ring that is required for cytokinesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
YDR061W |
YDR061W |
Protein with similarity to ABC transporter family members |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS116 |
YDR194C |
Mitochondrial transcription elongation factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAD9 |
YDR217C |
DNA damage-dependent checkpoint protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSD1 |
YDR293C |
Translational repressor |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMT7 |
YDR307W |
Putative protein mannosyltransferase similar to Pmt1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPQ2 |
YDR352W |
Putative vacuolar membrane transporter for cationic amino acids |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP20 |
YDR405W |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RSM28 |
YDR494W |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
QCR7 |
YDR529C |
Subunit 7 of ubiquinol cytochrome-c reductase (Complex III) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RML2 |
YEL050C |
Mitochondrial ribosomal protein of the large subunit (L2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SOM1 |
YEL059C-A |
Subunit of the mitochondrial inner membrane peptidase (IMP) |
genetic |
1 |
1 |
1 |
Negative Genetic |
HOM3 |
YER052C |
Aspartate kinase (L-aspartate 4-P-transferase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
VHR2 |
YER064C |
Non-essential nuclear protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
VTC1 |
YER072W |
Regulatory subunit of the vacuolar transporter chaperone (VTC) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF4 |
YGL115W |
Activating gamma subunit of the AMP-activated Snf1p kinase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SER2 |
YGR208W |
Phosphoserine phosphatase of the phosphoglycerate pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
MTM1 |
YGR257C |
Mitochondrial protein of the mitochondrial carrier family |
genetic |
1 |
1 |
1 |
Negative Genetic |
YHR078W |
YHR078W |
High osmolarity-regulated gene of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
REC104 |
YHR157W |
Protein involved in early stages of meiotic recombination |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAM33 |
YIL070C |
Acidic protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
MGA2 |
YIR033W |
ER membrane protein involved in regulation of OLE1 transcription |
genetic |
1 |
1 |
1 |
Negative Genetic |
TIM8 |
YJR135W-A |
Mitochondrial intermembrane space protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL106C-A |
YKL106C-A |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPE4 |
YLR146C |
Spermine synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HAP1 |
YLR256W |
Zinc finger transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RCF1 |
YML030W |
Cytochrome c oxidase subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SIP5 |
YMR140W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YMR155W |
YMR155W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPG5 |
YMR191W |
Protein required for proteasome assembly during quiescence |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPA2 |
YMR267W |
Mitochondrial inorganic pyrophosphatase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRP7 |
YNL005C |
Mitochondrial ribosomal protein of the large subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
POR1 |
YNL055C |
Mitochondrial porin (voltage-dependent anion channel) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCK1 |
YNL307C |
Dual-specificity ser/thr and tyrosine protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SKP2 |
YNL311C |
F-box protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PHO91 |
YNR013C |
Low-affinity vacuolar phosphate transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF12 |
YNR023W |
73 kDa subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PET494 |
YNR045W |
Mitochondrial translational activator specific for the COX3 mRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNR075C-A |
YNR075C-A |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
IMA2 |
YOL157C |
Isomaltase (alpha-1,6-glucosidase/alpha-methylglucosidase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPT2 |
YPL148C |
Phosphopantetheine:protein transferase (PPTase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RTC6 |
YPL183W-A |
Protein involved in translation |
genetic |
1 |
1 |
1 |
Negative Genetic |
YPR202W |
YPR202W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOS1 |
YLR078C |
v-SNARE (vesicle specific SNAP receptor) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC26 |
YFR036W |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEP3 |
YMR168C |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUR6 |
YER159C |
Subunit of a heterodimeric NC2 transcription regulator complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CYB2 |
YML054C |
Cytochrome b2 (L-lactate cytochrome-c oxidoreductase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FOX2 |
YKR009C |
3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ11 |
YLR290C |
Putative oxidoreductase, subunit of Coenzyme Q biosynthetic complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
GCD14 |
YJL125C |
Subunit of tRNA (1-methyladenosine) methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG33 |
YLR356W |
Mitochondrial mitophagy-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
DER1 |
YBR201W |
ER membrane protein that promotes export of misfolded polypeptides |
genetic |
1 |
1 |
1 |
Negative Genetic |
COQ4 |
YDR204W |
Protein with a role in ubiquinone (Coenzyme Q) biosynthesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI13 |
YLL031C |
ER membrane localized phosphoryltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVT5 |
YBL089W |
Putative transporter |
genetic |
1 |
1 |
1 |
Negative Genetic |
COX20 |
YDR231C |
Mitochondrial inner membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CRS5 |
YOR031W |
Copper-binding metallothionein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCC2 |
YDR270W |
Cu(+2)-transporting P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CBP4 |
YGR174C |
Mitochondrial protein required for assembly of cytochrome bc1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI10 |
YGL142C |
Integral membrane protein involved in GPI anchor synthesis |
genetic |
1 |
1 |
1 |
Positive Genetic |
CDC1 |
YDR182W |
Putative mannose-ethanolamine phosphate phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |