Standard name Systematic name Name description Description
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase; multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; mutation is functionally complemented by human HSD17B4
Visualize the interactome of FOX2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
FOX2 2 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2252 (2-enoyl-CoA hydratase (3-hydroxyoctadecanoyl-CoA)), r_2273 (3-hydroxyacyl-CoA dehydrogenase (3-oxooctanoyl-CoA)), r_2267 (3-hydroxyacyl-CoA dehydrogenase (3-oxododecanoyl-CoA)), r_2260 (2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-9-enoyl-CoA)), r_2280 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-octadec-9-enoyl-CoA)), r_2253 (2-enoyl-CoA hydratase (3-hydroxyhexacosanoyl-CoA)), r_2274 (3-hydroxyacyl-CoA dehydrogenase (3-oxoicosanoyl-CoA)), r_2261 (2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-7-enoyl-CoA)), r_2268 (3-hydroxyacyl-CoA dehydrogenase (3-oxohexadecanoyl-CoA)), r_2281 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-7-enoyl-CoA)), r_2254 (2-enoyl-CoA hydratase (3-hydroxybutanoyl-CoA)), r_2275 (3-hydroxyacyl-CoA dehydrogenase (3-oxodocosanoyl-CoA)), r_2262 (2-enoyl-CoA hydratase (3-hydroxy-cis-dodec-5-enoyl-CoA)), r_2248 (2-enoyl-CoA hydratase (3-hydroxydecanoyl-CoA)), r_2282 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-5-enoyl-CoA)), r_2269 (3-hydroxyacyl-CoA dehydrogenase (3-oxooctadecanoyl-CoA)), r_2255 (2-enoyl-CoA hydratase (3-hydroxyhexanoyl-CoA)), r_2263 (2-enoyl-CoA hydratase (3-hydroxy-cis-octadec-9-enoyl-CoA)), r_2276 (3-hydroxyacyl-CoA dehydrogenase (3-oxotetracosanoyl-CoA)), r_2249 (2-enoyl-CoA hydratase (3-hydroxydodecanoyl-CoA)), r_2256 (2-enoyl-CoA hydratase (3-hydroxyoctanoyl-CoA)), r_0057 (3-hydroxyacyl-CoA dehydrogenase (3-oxotetradecanoyl-CoA)), r_2270 (3-hydroxyacyl-CoA dehydrogenase (3-oxohexacosanoyl-CoA)), r_2264 (2-enoyl-CoA hydratase (3-hydroxy-cis-hexadec-7-enoyl-CoA)), r_2277 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-hexadec-9-enoyl-CoA)), r_2257 (2-enoyl-CoA hydratase (3-hydroxyicosanoyl-CoA)), r_2250 (2-enoyl-CoA hydratase (3-hydroxytetradecanoyl-CoA)), r_2271 (3-hydroxyacyl-CoA dehydrogenase (3-oxobutanoyl-CoA)), r_2265 (2-enoyl-CoA hydratase (3-hydroxy-cis-tetradec-5-enoyl-CoA)), r_2278 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-tetradec-7-enoyl-CoA)), r_2258 (2-enoyl-CoA hydratase (3-hydroxydocosanoyl-CoA)), r_2251 (2-enoyl-CoA hydratase (3-hydroxyhexadecanoyl-CoA)), r_2266 (3-hydroxyacyl-CoA dehydrogenase (3-oxodecanoyl-CoA)), r_2272 (3-hydroxyacyl-CoA dehydrogenase (3-oxohexanoyl-CoA)), r_2279 (3-hydroxyacyl-CoA dehydrogenase (3-oxo-cis-dodec-5-enoyl-CoA)), r_2259 (2-enoyl-CoA hydratase (3-hydroxytetracosanoyl-CoA))

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 3 2 3 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence, DNA to cDNA expression microarray evidence
VPS8 YAL002W Membrane-binding component of the CORVET complex genetic 2 1 2 Negative Genetic, Negative Genetic
TOG1 YER184C Transcriptional activator of oleate genes regulation 2 2 1 chromatin immunoprecipitation-PCR evidence, quantitative reverse transcription polymerase chain reaction evidence
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
GCN5 YGR252W Catalytic subunit of ADA and SAGA histone acetyltransferase complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
RFX1 YLR176C Major transcriptional repressor of DNA-damage-regulated genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
SPT10 YJL127C Histone H3 acetylase with a role in transcriptional regulation regulation 1 1 1 DNA to cDNA expression microarray evidence
ALA1 YOR335C Cytoplasmic and mitochondrial alanyl-tRNA synthetase genetic 1 1 1 Negative Genetic
CDC28 YBR160W Cyclin-dependent kinase (CDK) catalytic subunit genetic 1 1 1 Negative Genetic
CDC10 YCR002C Component of the septin ring, required for cytokinesis genetic 1 1 1 Negative Genetic
CDC11 YJR076C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CDC3 YLR314C Component of the septin ring that is required for cytokinesis genetic 1 1 1 Negative Genetic
CMD1 YBR109C Calmodulin genetic 1 1 1 Negative Genetic
ANP1 YEL036C Subunit of the alpha-1,6 mannosyltransferase complex genetic 1 1 1 Negative Genetic
AKL1 YBR059C Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
CMK1 YFR014C Calmodulin-dependent protein kinase physical 1 1 1 Biochemical Activity
ADH4 YGL256W Alcohol dehydrogenase isoenzyme type IV genetic 1 1 1 Negative Genetic
ENT3 YJR125C Protein containing an N-terminal epsin-like domain physical 1 1 1 Reconstituted Complex
CDC34 YDR054C Ubiquitin-conjugating enzyme (E2) physical 1 1 1 Affinity Capture-MS
APC5 YOR249C Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) genetic 1 1 1 Negative Genetic
CEP3 YMR168C Essential kinetochore protein genetic 1 1 1 Negative Genetic
DSE1 YER124C Daughter cell-specific protein genetic 1 1 1 Negative Genetic
PEX11 YOL147C Peroxisomal protein required for medium-chain fatty acid oxidation physical 1 1 1 Affinity Capture-Western
SMC3 YJL074C Subunit of the multiprotein cohesin complex physical 1 1 1 Co-fractionation
PBY1 YBR094W Putative tubulin tyrosine ligase associated with P-bodies physical 1 1 1 Affinity Capture-MS
RGA2 YDR379W GTPase-activating protein for polarity-establishment protein Cdc42p physical 1 1 1 Affinity Capture-MS
IPL1 YPL209C Aurora kinase of chromosomal passenger complex physical 1 1 1 Biochemical Activity
SKY1 YMR216C SR protein kinase (SRPK) physical 1 1 1 Biochemical Activity
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
TOS3 YGL179C Protein kinase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
RSP5 YER125W NEDD4 family E3 ubiquitin ligase physical 1 1 1 Reconstituted Complex
HSE1 YHL002W Subunit of the endosomal Vps27p-Hse1p complex physical 1 1 1 Two-hybrid
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
SBA1 YKL117W Co-chaperone that binds and regulates Hsp90 family chaperones physical 1 1 1 Reconstituted Complex
MIC60 YKR016W Component of the MICOS complex physical 1 1 1 Affinity Capture-MS
PEX5 YDR244W Peroxisomal membrane signal receptor for peroxisomal matrix proteins physical 1 1 1 Protein-peptide
SEC61 YLR378C Conserved ER protein translocation channel physical 1 1 1 Affinity Capture-MS
TIM23 YNR017W Essential component of the TIM23 complex physical 1 1 1 Affinity Capture-MS
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p genetic 1 1 1 Phenotypic Enhancement
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p genetic 1 1 1 Phenotypic Enhancement
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex genetic 1 1 1 Positive Genetic
NRG1 YDR043C Transcriptional repressor genetic 1 1 1 Negative Genetic
ILV1 YER086W Threonine deaminase, catalyzes first step in isoleucine biosynthesis genetic 1 1 1 Positive Genetic
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
YDJ1 YNL064C Type I HSP40 co-chaperone genetic 1 1 1 Negative Genetic
NPL3 YDR432W RNA-binding protein genetic 1 1 1 Synthetic Growth Defect
NUP192 YJL039C Essential subunit of inner ring of nuclear pore complex (NPC) genetic 1 1 1 Positive Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic
PRP24 YMR268C Splicing factor that reanneals snRNPs during spliceosome recycling genetic 1 1 1 Negative Genetic
TRS20 YBR254C Core component of transport protein particle (TRAPP) complexes I-III genetic 1 1 1 Negative Genetic
POL3 YDL102W Catalytic subunit of DNA polymerase delta genetic 1 1 1 Negative Genetic
RPO21 YDL140C RNA polymerase II largest subunit B220 genetic 1 1 1 Negative Genetic
TFB1 YDR311W Subunit of TFIIH and nucleotide excision repair factor 3 complexes genetic 1 1 1 Negative Genetic
SEC20 YDR498C Membrane glycoprotein v-SNARE genetic 1 1 1 Negative Genetic
RET2 YFR051C Delta subunit of the coatomer complex (COPI) genetic 1 1 1 Negative Genetic
MED6 YHR058C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
GPI12 YMR281W ER membrane protein involved in the second step of GPI anchor assembly genetic 1 1 1 Negative Genetic
LST8 YNL006W Protein required for the transport of Gap1p genetic 1 1 1 Negative Genetic
SMC5 YOL034W Subunit of the SMC5-SMC6 complex genetic 1 1 1 Negative Genetic
RPB2 YOR151C RNA polymerase II second largest subunit B150 genetic 1 1 1 Negative Genetic
GPN2 YOR262W Putative GTPase with a specific role in RNA pol II and polIII biogenes genetic 1 1 1 Negative Genetic
SEC62 YPL094C Essential subunit of Sec63 complex genetic 1 1 1 Negative Genetic
YEF1 YEL041W ATP-NADH kinase genetic 1 1 1 Negative Genetic
TUS1 YLR425W Guanine nucleotide exchange factor (GEF) that modulates Rho1p activity genetic 1 1 1 Negative Genetic
YPC1 YBR183W Alkaline ceramidase genetic 1 1 1 Positive Genetic
CYK3 YDL117W SH3-domain protein located in the bud neck and cytokinetic actin ring physical 1 1 1 Affinity Capture-MS
ARV1 YLR242C Cortical ER protein genetic 1 1 1 Negative Genetic