Standard name Systematic name Name description Description
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p; required for import of long-chain fatty acids into peroxisomes; similar to human adrenoleukodystrophy transportesr ABCD1 and ABCD2, and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder; human ABCD1 and ABCD2 can each partially complement yeast pxa1 pxa2 double null mutant
Visualize the interactome of PXA2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
no data no data no data

GFP localization & abundance

GFP localization GFP abundance
no data no data

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
PXA2 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_2231 (octadecenoate (n-C18:1) transport, cytoplasm-peroxisome), r_2223 (fatty acyl-CoA transport via ABC system (C18:0)), r_2220 (fatty acyl-CoA transport via ABC system (C14:0)), r_2226 (fatty acyl-CoA transport via ABC system (C22:0)), r_1774 (fatty acid transport), r_2228 (fatty acyl-CoA transport via ABC system (C26:0)), r_2222 (fatty acyl-CoA transport via ABC system (C16:1)), r_2225 (fatty acyl-CoA transport via ABC system (C20:0)), r_2219 (fatty acyl-CoA transport via ABC system (C12:0)), r_2224 (fatty acyl-CoA transport via ABC system (C18:1)), r_1772 (fatty acid transport), r_2221 (fatty acyl-CoA transport via ABC system (C16:0)), r_2227 (fatty acyl-CoA transport via ABC system (C24:0)), r_1771 (fatty acid transport), r_1236 (octadecanoate (n-C18:0) transport)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
PXA1 YPL147W Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa2p physical 3 2 2 Affinity Capture-Western, Two-hybrid, Affinity Capture-Western
NOP12 YOL041C Nucleolar protein involved in pre-25S rRNA processing genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
DPB3 YBR278W Third-largest subunit of DNA polymerase II (DNA polymerase epsilon) genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
MRT4 YKL009W Protein involved in mRNA turnover and ribosome assembly genetic 2 1 2 Negative Genetic, Negative Genetic
SSO2 YMR183C Plasma membrane t-SNARE genetic 2 1 2 Negative Genetic, Negative Genetic
RGL1 YPL066W Regulator of Rho1p signaling, cofactor of Tus1p genetic 2 1 2 Negative Genetic, Negative Genetic
CTT1 YGR088W Cytosolic catalase T genetic 2 1 2 Positive Genetic, Positive Genetic
ADH1 YOL086C Alcohol dehydrogenase physical 2 2 1 Affinity Capture-Western, PCA
ARF1 YDL192W ADP-ribosylation factor physical 2 2 1 Affinity Capture-Western, PCA
AHP1 YLR109W Thiol-specific peroxiredoxin physical 2 2 1 Affinity Capture-Western, PCA
GRX1 YCL035C Glutathione-dependent disulfide oxidoreductase physical 2 2 1 Affinity Capture-Western, PCA
ARF1 YDL192W ADP-ribosylation factor genetic 2 1 1 Negative Genetic, Negative Genetic
EAF1 YDR359C Component of the NuA4 histone acetyltransferase complex genetic 1 1 1 Positive Genetic
ARC1 YGL105W Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases physical 1 1 1 PCA
GUS1 YGL245W Glutamyl-tRNA synthetase (GluRS) physical 1 1 1 PCA
BMH1 YER177W 14-3-3 protein, major isoform physical 1 1 1 PCA
PAB1 YER165W Poly(A) binding protein physical 1 1 1 PCA
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CYS4 YGR155W Cystathionine beta-synthase physical 1 1 1 PCA
ENO1 YGR254W Enolase I, a phosphopyruvate hydratase genetic 1 1 1 Positive Genetic
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
ENO2 YHR174W Enolase II, a phosphopyruvate hydratase physical 1 1 1 PCA
FBA1 YKL060C Fructose 1,6-bisphosphate aldolase physical 1 1 1 PCA
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 PCA
FPR4 YLR449W Peptidyl-prolyl cis-trans isomerase (PPIase) physical 1 1 1 PCA
PGK1 YCR012W 3-phosphoglycerate kinase physical 1 1 1 PCA
PIL1 YGR086C Eisosome core component physical 1 1 1 PCA
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor genetic 1 1 1 Negative Genetic
BRR1 YPR057W snRNP protein component of spliceosomal snRNPs genetic 1 1 1 Negative Genetic
CAM1 YPL048W One of two isoforms of the gamma subunit of eEF1B physical 1 1 1 PCA
EFB1 YAL003W Translation elongation factor 1 beta physical 1 1 1 PCA
NEW1 YPL226W Translation termination and ribosome biogenesis factor genetic 1 1 1 Negative Genetic
EGD2 YHR193C Alpha subunit of the nascent polypeptide-associated complex (NAC) physical 1 1 1 PCA
HYP2 YEL034W Translation elongation factor eIF-5A physical 1 1 1 PCA
ADO1 YJR105W Adenosine kinase genetic 1 1 1 Negative Genetic
FKH1 YIL131C Forkhead family transcription factor genetic 1 1 1 Negative Genetic
CDC9 YDL164C DNA ligase I found in nucleus and mitochondria genetic 1 1 1 Negative Genetic
DOP1 YDR141C Protein involved in vesicular transport at trans-Golgi network (TGN) genetic 1 1 1 Negative Genetic
ADH3 YMR083W Mitochondrial alcohol dehydrogenase isozyme III genetic 1 1 1 Negative Genetic
FAA2 YER015W Medium chain fatty acyl-CoA synthetase genetic 1 1 1 Synthetic Growth Defect
HOM2 YDR158W Aspartic beta semi-aldehyde dehydrogenase physical 1 1 1 PCA
CYS3 YAL012W Cystathionine gamma-lyase genetic 1 1 1 Negative Genetic
ATP5 YDR298C Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase genetic 1 1 1 Negative Genetic
ARP1 YHR129C Actin-related protein of the dynactin complex genetic 1 1 1 Synthetic Lethality
ADE2 YOR128C Phosphoribosylaminoimidazole carboxylase physical 1 1 1 PCA
DAS2 YDR020C Putative protein of unknown function genetic 1 1 1 Negative Genetic
BNA6 YFR047C Quinolinate phosphoribosyl transferase genetic 1 1 1 Negative Genetic
DAL81 YIR023W Positive regulator of genes in multiple nitrogen degradation pathways physical 1 1 1 PCA
MCM3 YEL032W Protein involved in DNA replication genetic 1 1 1 Negative Genetic
GAL10 YBR019C UDP-glucose-4-epimerase genetic 1 1 1 Negative Genetic
PFY1 YOR122C Profilin physical 1 1 1 PCA
GTT1 YIR038C ER associated glutathione S-transferase physical 1 1 1 PCA
MOG1 YJR074W Conserved nuclear protein that interacts with GTP-Gsp1p physical 1 1 1 PCA
FOX2 YKR009C 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase genetic 1 1 1 Phenotypic Enhancement
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 1 1 1 Negative Genetic
SMD1 YGR074W Core Sm protein Sm D1 physical 1 1 1 Two-hybrid
VBA4 YDR119W Protein of unknown function physical 1 1 1 PCA
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease physical 1 1 1 PCA
RTN1 YDR233C Reticulon protein physical 1 1 1 PCA
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 PCA
SEC27 YGL137W Essential beta'-coat protein of the COPI coatomer physical 1 1 1 PCA
SGT2 YOR007C Glutamine-rich cytoplasmic cochaperone physical 1 1 1 PCA
SIN3 YOL004W Component of both the Rpd3S and Rpd3L histone deacetylase complexes physical 1 1 1 PCA
SOD1 YJR104C Cytosolic copper-zinc superoxide dismutase physical 1 1 1 PCA
SUI1 YNL244C Translation initiation factor eIF1 physical 1 1 1 PCA
TEF1 YPR080W Translational elongation factor EF-1 alpha physical 1 1 1 PCA
TIF2 YJL138C Translation initiation factor eIF4A physical 1 1 1 PCA
TIF3 YPR163C Translation initiation factor eIF-4B physical 1 1 1 PCA
TMA22 YJR014W Protein of unknown function physical 1 1 1 PCA
TPI1 YDR050C Triose phosphate isomerase, abundant glycolytic enzyme physical 1 1 1 PCA
TPM2 YIL138C Minor isoform of tropomyosin physical 1 1 1 PCA
TRX2 YGR209C Cytoplasmic thioredoxin isoenzyme physical 1 1 1 PCA
YLR257W YLR257W Protein of unknown function physical 1 1 1 PCA
YLR361C-A YLR361C-A Putative protein of unknown function physical 1 1 1 PCA
YMR099C YMR099C Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase) physical 1 1 1 PCA
YPL225W YPL225W Protein of unknown function physical 1 1 1 PCA
ZUO1 YGR285C Ribosome-associated chaperone physical 1 1 1 PCA
TOM1 YDR457W E3 ubiquitin ligase of the hect-domain class physical 1 1 1 Affinity Capture-MS
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 1 1 1 Two-hybrid
QCR8 YJL166W Subunit 8 of ubiquinol cytochrome-c reductase (Complex III) genetic 1 1 1 Negative Genetic
THR4 YCR053W Threonine synthase genetic 1 1 1 Positive Genetic
TEL2 YGR099W Subunit of the ASTRA complex, involved in chromatin remodeling genetic 1 1 1 Negative Genetic
VTI1 YMR197C Protein involved in cis-Golgi membrane traffic genetic 1 1 1 Negative Genetic
RRT2 YBR246W Methylesterase performing penultimate step of diphthamide biosynthesis genetic 1 1 1 Negative Genetic
UME6 YDR207C Rpd3L histone deacetylase complex subunit genetic 1 1 1 Negative Genetic
RVS167 YDR388W Calmodulin-binding actin-associated protein genetic 1 1 1 Negative Genetic
RTG2 YGL252C Sensor of mitochondrial dysfunction genetic 1 1 1 Negative Genetic
YHI9 YHR029C Protein of unknown function genetic 1 1 1 Negative Genetic
SRB2 YHR041C Subunit of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
SIC1 YLR079W Cyclin-dependent kinase inhibitor (CKI) genetic 1 1 1 Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 1 1 1 Negative Genetic
ATX1 YNL259C Cytosolic copper metallochaperone physical 1 1 1 PCA
ATG32 YIL146C Mitochondrial outer membrane protein required to initiate mitophagy genetic 1 1 1 Negative Genetic
MRP35 YNL122C Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
ALT1 YLR089C Alanine transaminase (glutamic pyruvic transaminase) genetic 1 1 1 Negative Genetic
IRC19 YLL033W Protein of unknown function genetic 1 1 1 Negative Genetic
EOS1 YNL080C Protein involved in N-glycosylation genetic 1 1 1 Negative Genetic
COQ4 YDR204W Protein with a role in ubiquinone (Coenzyme Q) biosynthesis genetic 1 1 1 Negative Genetic
MEP3 YPR138C Ammonium permease of high capacity and low affinity genetic 1 1 1 Positive Genetic
PET18 YCR020C Protein of unknown function genetic 1 1 1 Positive Genetic
COX20 YDR231C Mitochondrial inner membrane protein genetic 1 1 1 Negative Genetic
LNP1 YHR192W Lunapark family member involved in ER network formation genetic 1 1 1 Negative Genetic
NRK1 YNL129W Nicotinamide riboside kinase genetic 1 1 1 Negative Genetic