Standard name Systematic name Name description Description
TPM2 YIL138C Minor isoform of tropomyosin Minor isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p; TPM2 has a paralog, TPM1, that arose from the whole genome duplication
Visualize the interactome of TPM2
Links to external databases:
  SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)
S 80

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.937 0.939 0.897
Cell Periphery NaN 0.057 NaN
ER NaN 0.065 NaN
Cort. Patches NaN NaN 0.051

GFP localization & abundance

GFP localization GFP abundance
cytoplasm 11100

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
TPM2 0 0 3 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
TPM1 YNL079C Major isoform of tropomyosin genetic 12 3 11 Dosage Rescue, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
TPM2 YIL138C Minor isoform of tropomyosin physical 4 3 4 Two-hybrid, PCA, Co-crystal Structure, PCA
SAS2 YMR127C Histone acetyltransferase (HAT) catalytic subunit of the SAS complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
BNR1 YIL159W Formin genetic 2 2 2 Dosage Rescue, Phenotypic Enhancement
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 2 1 2 Reconstituted Complex, Reconstituted Complex
MMS2 YGL087C Ubiquitin-conjugating enzyme variant genetic 2 1 2 Negative Genetic, Negative Genetic
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 2 1 2 PCA, PCA
CMG1 YLR271W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
YAR023C YAR023C Putative integral membrane protein genetic 2 1 2 Negative Genetic, Negative Genetic
YDL180W YDL180W Putative protein of unknown function genetic 2 1 2 Negative Genetic, Negative Genetic
TGL5 YOR081C Bifunctional triacylglycerol lipase and LPA acyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
PHB2 YGR231C Subunit of the prohibitin complex (Phb1p-Phb2p) genetic 2 1 2 Negative Genetic, Negative Genetic
SYT1 YPR095C Guanine nucleotide exchange factor (GEF) for Arf proteins genetic 2 1 2 Negative Genetic, Negative Genetic
SHO1 YER118C Transmembrane osmosensor for filamentous growth and HOG pathways physical 2 2 1 Two-hybrid, PCA
UBP1 YDL122W Ubiquitin-specific protease genetic 2 1 1 Negative Genetic, Negative Genetic
NCS6 YGL211W Protein required for uridine thiolation of Gln, Lys, and Glu tRNAs genetic 2 1 1 Negative Genetic, Negative Genetic
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
HFI1 YPL254W Adaptor protein required for structural integrity of the SAGA complex regulation 1 1 1 DNA to cDNA expression microarray evidence
SPT20 YOL148C Subunit of the SAGA transcriptional regulatory complex regulation 1 1 1 DNA to cDNA expression microarray evidence
YAP6 YDR259C Basic leucine zipper (bZIP) transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
UME6 YDR207C Rpd3L histone deacetylase complex subunit regulation 1 1 1 DNA to cDNA expression microarray evidence
SWI5 YDR146C Transcription factor that recruits Mediator and Swi/Snf complexes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
IKI3 YLR384C Subunit of Elongator complex genetic 1 1 1 Negative Genetic
MDM20 YOL076W Non-catalytic subunit of the NatB N-terminal acetyltransferase genetic 1 1 1 Dosage Rescue
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
BNI1 YNL271C Formin genetic 1 1 1 Phenotypic Enhancement
GCN1 YGL195W Positive regulator of the Gcn2p kinase activity physical 1 1 1 PCA
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 1 1 1 Affinity Capture-RNA
LSM7 YNL147W Lsm (Like Sm) protein genetic 1 1 1 Negative Genetic
NRD1 YNL251C RNA-binding subunit of Nrd1 complex genetic 1 1 1 Negative Genetic
SGF29 YCL010C Component of the HAT/Core module of the SAGA, SLIK, and ADA complexes genetic 1 1 1 Positive Genetic
SRO9 YCL037C Cytoplasmic RNA-binding protein physical 1 1 1 Affinity Capture-RNA
SRO9 YCL037C Cytoplasmic RNA-binding protein genetic 1 1 1 Dosage Rescue
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
SWP1 YMR149W Delta subunit of the oligosaccharyl transferase glycoprotein complex genetic 1 1 1 Negative Genetic
CDC13 YDL220C Single stranded DNA-binding protein found at TG1-3 telomere G-tails genetic 1 1 1 Synthetic Rescue
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
SHP1 YBL058W UBX domain-containing substrate adaptor for Cdc48p genetic 1 1 1 Negative Genetic
OCA1 YNL099C Putative protein tyrosine phosphatase genetic 1 1 1 Negative Genetic
SNO2 YNL334C Protein of unknown function genetic 1 1 1 Negative Genetic
DBF2 YGR092W Ser/Thr kinase involved in transcription and stress response genetic 1 1 1 Negative Genetic
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Positive Genetic
NDL1 YLR254C Homolog of nuclear distribution factor NudE genetic 1 1 1 Positive Genetic
STD1 YOR047C Protein involved in control of glucose-regulated gene expression genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
RAD9 YDR217C DNA damage-dependent checkpoint protein genetic 1 1 1 Phenotypic Enhancement
TOR2 YKL203C PIK-related protein kinase and rapamycin target genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BUB1 YGR188C Protein kinase involved in the cell cycle checkpoint into anaphase genetic 1 1 1 Positive Genetic
SEC6 YIL068C Essential 88kDa subunit of the exocyst complex genetic 1 1 1 Phenotypic Suppression
STE50 YCL032W Adaptor protein for various signaling pathways genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Phenotypic Enhancement
MON2 YNL297C Protein with a role in endocytosis and vacuole integrity genetic 1 1 1 Negative Genetic
PXA2 YKL188C Subunit of heterodimeric peroxisomal ABC transport complex, with Pxa1p physical 1 1 1 PCA
TPM1 YNL079C Major isoform of tropomyosin physical 1 1 1 Affinity Capture-MS
ZIP1 YDR285W Transverse filament protein of the synaptonemal complex physical 1 1 1 Two-hybrid
YHL008C YHL008C Putative protein of unknown function genetic 1 1 1 Negative Genetic
YHL017W YHL017W Putative protein of unknown function genetic 1 1 1 Positive Genetic
URA7 YBL039C Major CTP synthase isozyme (see also URA8) genetic 1 1 1 Negative Genetic
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p genetic 1 1 1 Negative Genetic
YKR018C YKR018C Protein of unknown function genetic 1 1 1 Negative Genetic
YLR012C YLR012C Putative protein of unknown function genetic 1 1 1 Negative Genetic
VPS1 YKR001C Dynamin-like GTPase required for vacuolar sorting genetic 1 1 1 Positive Genetic
LYS20 YDL182W Homocitrate synthase isozyme and functions in DNA repair genetic 1 1 1 Negative Genetic
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
BYE1 YKL005C Negative regulator of transcription elongation genetic 1 1 1 Negative Genetic
COQ6 YGR255C Flavin-dependent monooxygenase involved in ubiquinone biosynthesis genetic 1 1 1 Positive Genetic
GIS2 YNL255C Translational activator for mRNAs with internal ribosome entry sites physical 1 1 1 Affinity Capture-RNA
ABZ2 YMR289W Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase) genetic 1 1 1 Negative Genetic
MTM1 YGR257C Mitochondrial protein of the mitochondrial carrier family genetic 1 1 1 Negative Genetic
AAD14 YNL331C Putative aryl-alcohol dehydrogenase genetic 1 1 1 Negative Genetic
FAA3 YIL009W Long chain fatty acyl-CoA synthetase genetic 1 1 1 Negative Genetic
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
SEC12 YNR026C Guanine nucleotide exchange factor (GEF) genetic 1 1 1 Positive Genetic
PHO3 YBR092C Constitutively expressed acid phosphatase similar to Pho5p genetic 1 1 1 Positive Genetic
KCH1 YJR054W Potassium transporter that mediates K+ influx genetic 1 1 1 Negative Genetic
FYV12 YOR183W Protein of unknown function genetic 1 1 1 Negative Genetic