Standard name Systematic name Name description Description
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex Protein adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance
Visualize the interactome of SHE3
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Bud 0.119 0.165 0.140
Cell Periphery 0.052 NaN 0.116
Cort. Patches 0.200 0.364 0.357
Cytoplasm 0.300 0.240 0.167
ER 0.114 0.322 0.151
Endosome 0.052 NaN NaN
Mito 0.357 0.099 0.264
Vac/Vac Memb 0.052 NaN NaN
Golgi NaN NaN 0.120

GFP localization & abundance

GFP localization GFP abundance
ambiguous, cytoplasm, cell periphery, bud 1010

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
SHE3 0 0 0 0 0

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
MYO4 YAL029C Type V myosin motor involved in actin-based transport of cargos physical 28 8 18 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Co-purification, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Co-fractionation, Reconstituted Complex, Affinity Capture-Western, PCA, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-MS, Co-fractionation, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex
SHE2 YKL130C RNA-binding protein that binds specific mRNAs and interacts with She3p physical 21 6 17 Affinity Capture-MS, Two-hybrid, Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, PCA, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Two-hybrid, Affinity Capture-Western, Reconstituted Complex, Co-crystal Structure, Co-crystal Structure, Reconstituted Complex, Reconstituted Complex, Co-crystal Structure, Reconstituted Complex
MLC1 YGL106W Essential light chain for Myo1p physical 4 1 4 Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS
ASH1 YKL185W Component of the Rpd3L histone deacetylase complex physical 2 2 2 Affinity Capture-RNA, Protein-RNA
REB1 YBR049C RNA polymerase I enhancer binding protein regulation 2 1 2 chromatin immunoprecipitation-chip evidence, chromatin immunoprecipitation-chip evidence
DHH1 YDL160C Cytoplasmic DEAD-box helicase and mRNA decapping activator physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
CMD1 YBR109C Calmodulin physical 2 1 2 Affinity Capture-MS, Affinity Capture-MS
HSP82 YPL240C Hsp90 chaperone physical 2 1 2 Two-hybrid, Two-hybrid
TPM2 YIL138C Minor isoform of tropomyosin physical 2 1 2 PCA, PCA
TPS2 YDR074W Phosphatase subunit of the trehalose-6-P synthase/phosphatase complex genetic 2 1 2 Negative Genetic, Negative Genetic
VPS72 YDR485C Htz1p-binding component of the SWR1 complex genetic 2 1 2 Negative Genetic, Negative Genetic
PMT6 YGR199W Protein O-mannosyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
MUD1 YBR119W U1 snRNP A protein physical 2 2 1 Affinity Capture-Western, Affinity Capture-MS
FKH1 YIL131C Forkhead family transcription factor regulation 1 1 1 ChEC-Seq experiments
SFP1 YLR403W Regulates transcription of ribosomal protein and biogenesis genes regulation 1 1 1 DNA to cDNA expression microarray evidence
FKH2 YNL068C Forkhead family transcription factor regulation 1 1 1 chromatin immunoprecipitation- exonuclease evidence
UGA3 YDL170W Transcriptional activator for GABA-dependent induction of GABA genes regulation 1 1 1 chromatin immunoprecipitation-chip evidence
CEF1 YMR213W Essential splicing factor genetic 1 1 1 Negative Genetic
EAF5 YEL018W Non-essential subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Positive Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 1 1 1 Positive Genetic
RPC25 YKL144C RNA polymerase III subunit C25 genetic 1 1 1 Positive Genetic
PWP1 YLR196W Protein with WD-40 repeats involved in rRNA processing physical 1 1 1 Affinity Capture-MS
ACT1 YFL039C Actin, structural protein in cytoskeleton physical 1 1 1 Affinity Capture-Western
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
RTT10 YPL183C WD40 domain-containing protein involved in endosomal recycling genetic 1 1 1 Negative Genetic
ARC35 YNR035C Subunit of the ARP2/3 complex genetic 1 1 1 Positive Genetic
CCA1 YER168C ATP (CTP):tRNA-specific tRNA nucleotidyltransferase genetic 1 1 1 Positive Genetic
CDC12 YHR107C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
BUD31 YCR063W Component of the SF3b subcomplex of the U2 snRNP genetic 1 1 1 Negative Genetic
CTK1 YKL139W Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) genetic 1 1 1 Negative Genetic
DOA1 YKL213C WD-repeat protein involved in ubiquitin-mediated protein degradation genetic 1 1 1 Negative Genetic
HSL1 YKL101W Nim1p-related protein kinase physical 1 1 1 Biochemical Activity
LAS17 YOR181W Actin assembly factor physical 1 1 1 Affinity Capture-MS
CRM1 YGR218W Nuclear export factor, exportin physical 1 1 1 Affinity Capture-MS
MCM5 YLR274W Component of the Mcm2-7 hexameric helicase complex physical 1 1 1 Affinity Capture-MS
MRPL24 YMR193W Mitochondrial ribosomal protein of the large subunit genetic 1 1 1 Negative Genetic
GEP3 YOR205C Protein required for mitochondrial ribosome small subunit biogenesis genetic 1 1 1 Negative Genetic
CMR1 YDL156W Nuclear protein with role in transcription, protein quality control genetic 1 1 1 Positive Genetic
HTZ1 YOL012C Histone variant H2AZ genetic 1 1 1 Positive Genetic
IES5 YER092W Non-essential INO80 chromatin remodeling complex subunit genetic 1 1 1 Positive Genetic
AHA1 YDR214W Co-chaperone that binds Hsp82p and activates its ATPase activity genetic 1 1 1 Negative Genetic
GIM5 YML094W Subunit of the heterohexameric cochaperone prefoldin complex genetic 1 1 1 Positive Genetic
IDH2 YOR136W Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase genetic 1 1 1 Positive Genetic
POP7 YBR167C Subunit of RNase MRP, nuclear RNase P and telomerase genetic 1 1 1 Negative Genetic
PTI1 YGR156W Essential component of CPF (cleavage and polyadenylation factor) genetic 1 1 1 Negative Genetic
PHO23 YNL097C Component of the Rpd3L histone deacetylase complex genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p genetic 1 1 1 Negative Genetic
CDC25 YLR310C Membrane bound guanine nucleotide exchange factor physical 1 1 1 Two-hybrid
SCP160 YJL080C Essential RNA-binding G protein effector of mating response pathway physical 1 1 1 Affinity Capture-MS
ROM2 YLR371W Guanine nucleotide exchange factor (GEF) for Rho1p and Rho2p genetic 1 1 1 Negative Genetic
DRS2 YAL026C Trans-golgi network aminophospholipid translocase (flippase) genetic 1 1 1 Positive Genetic
BDH2 YAL061W Putative medium-chain alcohol dehydrogenase with similarity to BDH1 genetic 1 1 1 Negative Genetic
PHO85 YPL031C Cyclin-dependent kinase physical 1 1 1 Biochemical Activity
CAF20 YOR276W Phosphoprotein of the mRNA cap-binding complex physical 1 1 1 Affinity Capture-RNA
ATG17 YLR423C Scaffold protein responsible for phagophore assembly site organization physical 1 1 1 Two-hybrid
GRR1 YJR090C F-box protein component of an SCF ubiquitin-ligase complex physical 1 1 1 Two-hybrid
RVS161 YCR009C Amphiphysin-like lipid raft protein genetic 1 1 1 Negative Genetic
KOG1 YHR186C Subunit of TORC1 genetic 1 1 1 Negative Genetic
MAK11 YKL021C Protein involved in an early step of 60S ribosomal subunit biogenesis genetic 1 1 1 Positive Genetic
KSP1 YHR082C Serine/threonine protein kinase physical 1 1 1 Biochemical Activity
SUP45 YBR143C Polypeptide release factor (eRF1) in translation termination physical 1 1 1 Affinity Capture-MS
SUL2 YLR092W High affinity sulfate permease physical 1 1 1 Affinity Capture-MS
TAF1 YGR274C TFIID subunit, involved in RNA pol II transcription initiation physical 1 1 1 Affinity Capture-MS
SNF1 YDR477W AMP-activated S/T protein kinase physical 1 1 1 Biochemical Activity
STE20 YHL007C Cdc42p-activated signal transducing kinase physical 1 1 1 Biochemical Activity
TPK1 YJL164C cAMP-dependent protein kinase catalytic subunit physical 1 1 1 Biochemical Activity
YCK1 YHR135C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
YCK2 YNL154C Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform physical 1 1 1 Biochemical Activity
SHE3 YBR130C Protein adaptor between Myo4p and the She2p-mRNA complex physical 1 1 1 PCA
VAM6 YDL077C Guanine nucleotide exchange factor for the GTPase Gtr1p physical 1 1 1 Affinity Capture-MS
TMA46 YOR091W Protein of unknown function that associates with translating ribosomes physical 1 1 1 Affinity Capture-MS
XRN1 YGL173C Evolutionarily-conserved 5'-3' exonuclease genetic 1 1 1 Negative Genetic
THP2 YHR167W Subunit of the THO and TREX complexes genetic 1 1 1 Positive Genetic
VPH2 YKL119C Integral membrane protein required for V-ATPase function genetic 1 1 1 Negative Genetic
YME1 YPR024W Catalytic subunit of i-AAA protease complex genetic 1 1 1 Negative Genetic
SRP102 YKL154W Signal recognition particle (SRP) receptor beta subunit genetic 1 1 1 Positive Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
TOK1 YJL093C Outward-rectifier potassium channel of the plasma membrane genetic 1 1 1 Negative Genetic
TAL1 YLR354C Transaldolase, enzyme in the non-oxidative pentose phosphate pathway genetic 1 1 1 Negative Genetic
RAD53 YPL153C DNA damage response kinase physical 1 1 1 Biochemical Activity
BIR1 YJR089W Subunit of chromosomal passenger complex (CPC) genetic 1 1 1 Negative Genetic
MLP2 YIL149C Myosin-like protein associated with the nuclear envelope physical 1 1 1 Affinity Capture-MS
IME2 YJL106W Serine/threonine protein kinase involved in activation of meiosis physical 1 1 1 Biochemical Activity
HOF1 YMR032W F-BAR protein that regulates actin cytoskeleton organization genetic 1 1 1 Positive Genetic
ATG1 YGL180W Protein serine/threonine kinase physical 1 1 1 Biochemical Activity
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Affinity Capture-MS
KEG1 YFR042W Integral membrane protein of the ER genetic 1 1 1 Negative Genetic
ITT1 YML068W Protein that modulates the efficiency of translation termination genetic 1 1 1 Positive Genetic
RPL20B YOR312C Ribosomal 60S subunit protein L20B genetic 1 1 1 Negative Genetic
RPL22A YLR061W Ribosomal 60S subunit protein L22A genetic 1 1 1 Positive Genetic
CSE4 YKL049C Centromeric histone H3-like protein genetic 1 1 1 Positive Genetic
BUR6 YER159C Subunit of a heterodimeric NC2 transcription regulator complex genetic 1 1 1 Negative Genetic
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
NYV1 YLR093C v-SNARE component of the vacuolar SNARE complex genetic 1 1 1 Negative Genetic
PRK1 YIL095W Ser/Thr protein kinase physical 1 1 1 Biochemical Activity
GYP1 YOR070C Cis-golgi GTPase-activating protein (GAP) for yeast Rabs genetic 1 1 1 Negative Genetic
CLA4 YNL298W Cdc42p-activated signal transducing kinase genetic 1 1 1 Dosage Growth Defect
HAC1 YFL031W Basic leucine zipper (bZIP) transcription factor (ATF/CREB1 homolog) physical 1 1 1 Affinity Capture-RNA
EAF6 YJR082C Subunit of the NuA4 acetyltransferase complex genetic 1 1 1 Positive Genetic
MIP1 YOR330C Mitochondrial DNA polymerase gamma genetic 1 1 1 Negative Genetic
AIM44 YPL158C Regulator of Cdc42p and Rho1p genetic 1 1 1 Positive Genetic
DRN1 YGR093W Splicing factor that modulates turnover of branched RNAs by Dbr1p genetic 1 1 1 Positive Genetic
GEP5 YLR091W Protein of unknown function genetic 1 1 1 Positive Genetic
RTR1 YER139C Dual specificity protein phosphatase genetic 1 1 1 Positive Genetic
PUF2 YPR042C PUF family mRNA-binding protein physical 1 1 1 Affinity Capture-RNA
MDM32 YOR147W Mitochondrial inner membrane protein with similarity to Mdm31p genetic 1 1 1 Negative Genetic
HER2 YMR293C Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex genetic 1 1 1 Negative Genetic
MEP2 YNL142W Ammonium permease involved in regulation of pseudohyphal growth genetic 1 1 1 Negative Genetic
GPI11 YDR302W ER membrane protein involved in a late step of GPI anchor assembly genetic 1 1 1 Negative Genetic