NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
physical |
29 |
8 |
23 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-localization, Two-hybrid, Co-purification, Affinity Capture-Western, Affinity Capture-Western, Reconstituted Complex, Affinity Capture-Western, FRET, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
24 |
6 |
21 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Two-hybrid, Reconstituted Complex, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS, Two-hybrid, Co-purification, Affinity Capture-Western, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
physical |
16 |
6 |
13 |
Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-Western, Two-hybrid, Co-fractionation, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-MS, Two-hybrid, Co-purification, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex, Reconstituted Complex |
DSN1 |
YIR010W |
Essential component of the outer kinetochore MIND complex |
physical |
16 |
3 |
11 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-MS, Reconstituted Complex, Affinity Capture-Western, Affinity Capture-MS |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
10 |
4 |
7 |
Reconstituted Complex, Reconstituted Complex, Two-hybrid, Two-hybrid, Two-hybrid, Two-hybrid, Affinity Capture-Western, Co-purification, Reconstituted Complex, Two-hybrid |
NUF2 |
YOL069W |
Component of the kinetochore-associated Ndc80 complex |
genetic |
5 |
3 |
4 |
Synthetic Lethality, Synthetic Rescue, Negative Genetic, Negative Genetic, Negative Genetic |
DAM1 |
YGR113W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
5 |
3 |
3 |
Negative Genetic, Negative Genetic, Synthetic Lethality, Phenotypic Enhancement, Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
regulation |
5 |
5 |
2 |
chromatin immunoprecipitation-qPCR evidence, DNA to cDNA expression microarray evidence, fluorescence in situ hybridization evidence, northern blot evidence, qualitative western immunoblotting evidence |
MPS1 |
YDL028C |
Dual-specificity kinase |
physical |
4 |
3 |
4 |
Two-hybrid, Affinity Capture-Western, Affinity Capture-MS, Affinity Capture-MS |
MTW1 |
YAL034W-A |
Essential component of the MIND kinetochore complex |
physical |
4 |
3 |
3 |
Affinity Capture-MS, Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
4 |
3 |
3 |
Dosage Rescue, Synthetic Lethality, Negative Genetic, Negative Genetic |
SPC25 |
YER018C |
Component of the kinetochore-associated Ndc80 complex |
genetic |
4 |
3 |
3 |
Dosage Rescue, Dosage Rescue, Synthetic Lethality, Negative Genetic |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
genetic |
4 |
2 |
3 |
Phenotypic Enhancement, Negative Genetic, Negative Genetic, Negative Genetic |
FIN1 |
YDR130C |
Spindle pole body-related intermediate filament protein |
physical |
4 |
3 |
2 |
Two-hybrid, Affinity Capture-MS, Affinity Capture-Western, Affinity Capture-Western |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
genetic |
4 |
2 |
2 |
Positive Genetic, Negative Genetic, Negative Genetic, Negative Genetic |
CNN1 |
YFR046C |
Kinetochore protein |
physical |
4 |
2 |
2 |
Affinity Capture-MS, Co-purification, Affinity Capture-MS, Co-purification |
STU2 |
YLR045C |
Microtubule polymerase of the XMAP215/Dis1 family |
physical |
3 |
3 |
3 |
FRET, Reconstituted Complex, Affinity Capture-MS |
MAD2 |
YJL030W |
Component of the spindle-assembly checkpoint complex |
genetic |
3 |
2 |
3 |
Synthetic Rescue, Negative Genetic, Negative Genetic |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
3 |
2 |
3 |
Synthetic Lethality, Negative Genetic, Negative Genetic |
MUM2 |
YBR057C |
Protein essential for meiotic DNA replication and sporulation |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
3 |
1 |
2 |
Two-hybrid, Two-hybrid, Two-hybrid |
PDS1 |
YDR113C |
Securin |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
MAD1 |
YGL086W |
Coiled-coil protein involved in spindle-assembly checkpoint |
genetic |
3 |
1 |
2 |
Negative Genetic, Negative Genetic, Negative Genetic |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
2 |
2 |
2 |
chromatin immunoprecipitation-chip evidence, ChEC-Seq experiments |
CDC73 |
YLR418C |
Component of the Paf1p complex |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
LEA1 |
YPL213W |
Component of U2 snRNP complex |
genetic |
2 |
2 |
2 |
Positive Genetic, Negative Genetic |
NDC80 |
YIL144W |
Component of the kinetochore-associated Ndc80 complex |
physical |
2 |
2 |
2 |
Two-hybrid, FRET |
SPC34 |
YKR037C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
2 |
2 |
Co-purification, Reconstituted Complex |
ASK1 |
YKL052C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
2 |
2 |
2 |
Co-purification, Reconstituted Complex |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
genetic |
2 |
2 |
2 |
Synthetic Rescue, Phenotypic Enhancement |
CBF2 |
YGR140W |
Essential kinetochore protein |
genetic |
2 |
2 |
2 |
Synthetic Lethality, Negative Genetic |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ARP4 |
YJL081C |
Nuclear actin-related protein involved in chromatin remodeling |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CBC2 |
YPL178W |
Small subunit of the heterodimeric cap binding complex with Sto1p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
BUD31 |
YCR063W |
Component of the SF3b subcomplex of the U2 snRNP |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
MED1 |
YPR070W |
Subunit of the RNA polymerase II mediator complex |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
BUB3 |
YOR026W |
Kinetochore checkpoint WD40 repeat protein |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CDC7 |
YDL017W |
S/T kinase and catalytic subunit of DDK (Dbf4-dependent kinase) |
genetic |
2 |
1 |
2 |
Positive Genetic, Positive Genetic |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
CSM1 |
YCR086W |
Nucleolar protein that mediates homolog segregation during meiosis I |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
MAD3 |
YJL013C |
Subunit of spindle-assembly checkpoint complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NIP100 |
YPL174C |
Large subunit of the dynactin complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
OKP1 |
YGR179C |
Outer kinetochore protein required for accurate chromosome segregation |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SMC3 |
YJL074C |
Subunit of the multiprotein cohesin complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
ORC4 |
YPR162C |
Subunit of the origin recognition complex (ORC) |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NUP60 |
YAR002W |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
SAC3 |
YDR159W |
mRNA export factor |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
physical |
2 |
1 |
2 |
Biochemical Activity, Biochemical Activity |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
ERG3 |
YLR056W |
C-5 sterol desaturase |
genetic |
2 |
1 |
2 |
Negative Genetic, Negative Genetic |
NDT80 |
YHR124W |
Meiosis-specific transcription factor |
regulation |
2 |
2 |
1 |
northern blot evidence, qualitative western immunoblotting evidence |
IPL1 |
YPL209C |
Aurora kinase of chromosomal passenger complex |
regulation |
2 |
2 |
1 |
protein kinase assay evidence, qualitative western immunoblotting evidence |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
2 |
2 |
1 |
Reconstituted Complex, Affinity Capture-Western |
SMC2 |
YFR031C |
Subunit of the condensin complex |
physical |
2 |
2 |
1 |
Affinity Capture-Western, Two-hybrid |
NKP2 |
YLR315W |
Central kinetochore protein and subunit of the Ctf19 complex |
physical |
2 |
2 |
1 |
PCA, Two-hybrid |
CEG1 |
YGL130W |
Guanylyltransferase involved in mRNA 5' capping |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
FIP1 |
YJR093C |
Subunit of cleavage polyadenylation factor (CPF) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RNA1 |
YMR235C |
GTPase activating protein (GAP) for Gsp1p |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
RTT103 |
YDR289C |
Protein involved in transcription termination by RNA polymerase II |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SSM4 |
YIL030C |
Membrane-embedded ubiquitin-protein ligase and retrotranslocase |
genetic |
2 |
1 |
1 |
Synthetic Rescue, Synthetic Rescue |
MUB1 |
YMR100W |
MYND domain-containing protein |
genetic |
2 |
1 |
1 |
Negative Genetic, Negative Genetic |
SFP1 |
YLR403W |
Regulates transcription of ribosomal protein and biogenesis genes |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
FKH2 |
YNL068C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
ChEC-Seq experiments |
RGR1 |
YLR071C |
Subunit of the RNA polymerase II mediator complex |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
YAP5 |
YIR018W |
Basic leucine zipper (bZIP) iron-sensing transcription factor |
regulation |
1 |
1 |
1 |
DNA to cDNA expression microarray evidence |
SET2 |
YJL168C |
Histone methyltransferase with a role in transcriptional elongation |
regulation |
1 |
1 |
1 |
transcript expression evidence |
SET3 |
YKR029C |
Defining member of the SET3 histone deacetylase complex |
regulation |
1 |
1 |
1 |
transcript expression evidence |
AME1 |
YBR211C |
Essential kinetochore protein associated with microtubules and SPBs |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CTF3 |
YLR381W |
Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p |
genetic |
1 |
1 |
1 |
Negative Genetic |
LEO1 |
YOR123C |
Component of the Paf1 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKB1 |
YGL019W |
Beta regulatory subunit of casein kinase 2 (CK2) |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
GLC7 |
YER133W |
Type 1 S/T protein phosphatase (PP1) catalytic subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRX1 |
YOL077C |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR2 |
YER172C |
RNA-dependent ATPase RNA helicase (DEIH box) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM21 |
YDR318W |
Component of the kinetochore sub-complex COMA |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
KEL3 |
YPL263C |
Cytoplasmic protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
LSM1 |
YJL124C |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC48 |
YDL126C |
AAA ATPase with protein-unfoldase activity |
genetic |
1 |
1 |
1 |
Negative Genetic |
MED4 |
YOR174W |
Subunit of the RNA polymerase II mediator complex |
physical |
1 |
1 |
1 |
Two-hybrid |
GCD1 |
YOR260W |
Gamma subunit of the translation initiation factor eIF2B |
genetic |
1 |
1 |
1 |
Negative Genetic |
AAH1 |
YNL141W |
Adenine deaminase (adenine aminohydrolase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
ABD1 |
YBR236C |
Methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ACC1 |
YNR016C |
Acetyl-CoA carboxylase, biotin containing enzyme |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC1 |
YNL172W |
Largest subunit of the Anaphase-Promoting Complex/Cyclosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
ARC35 |
YNR035C |
Subunit of the ARP2/3 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
ARP3 |
YJR065C |
Essential component of the Arp2/3 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET3 |
YKR068C |
Core component of transport protein particle (TRAPP) complexes I-III |
genetic |
1 |
1 |
1 |
Negative Genetic |
BUD14 |
YAR014C |
Protein involved in bud-site selection |
physical |
1 |
1 |
1 |
Two-hybrid |
BOI2 |
YER114C |
Protein involved in polar growth |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC12 |
YHR107C |
Component of the septin ring that is required for cytokinesis |
physical |
1 |
1 |
1 |
Two-hybrid |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AVO1 |
YOL078W |
Component of the membrane-bound TORC2 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CKS1 |
YBR135W |
Cyclin-dependent protein kinase regulatory subunit and adaptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNS1 |
YBR155W |
TPR-containing co-chaperone |
physical |
1 |
1 |
1 |
Two-hybrid |
COP1 |
YDL145C |
Alpha subunit of COPI vesicle coatomer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
CTK1 |
YKL139W |
Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I) |
genetic |
1 |
1 |
1 |
Positive Genetic |
CUS1 |
YMR240C |
Protein required for assembly of U2 snRNP into the spliceosome |
genetic |
1 |
1 |
1 |
Positive Genetic |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
physical |
1 |
1 |
1 |
Two-hybrid |
LSM7 |
YNL147W |
Lsm (Like Sm) protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK3 |
YPR051W |
Catalytic subunit of the NatC type N-terminal acetyltransferase (NAT) |
genetic |
1 |
1 |
1 |
Negative Genetic |
MAK5 |
YBR142W |
Essential nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCD1 |
YDL003W |
Essential alpha-kleisin subunit of the cohesin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
MCM6 |
YGL201C |
Protein involved in DNA replication |
physical |
1 |
1 |
1 |
Two-hybrid |
COG3 |
YER157W |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NAM8 |
YHR086W |
RNA binding protein, component of the U1 snRNP protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GIM3 |
YNL153C |
Subunit of the heterohexameric cochaperone prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
DEP1 |
YAL013W |
Component of the Rpd3L histone deacetylase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BZZ1 |
YHR114W |
SH3 domain protein implicated in regulating actin polymerization |
physical |
1 |
1 |
1 |
Two-hybrid |
CCT8 |
YJL008C |
Subunit of the cytosolic chaperonin Cct ring complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
BRR1 |
YPR057W |
snRNP protein component of spliceosomal snRNPs |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSE1 |
YHL002W |
Subunit of the endosomal Vps27p-Hse1p complex |
physical |
1 |
1 |
1 |
Two-hybrid |
FUN19 |
YAL034C |
Non-essential protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
BOI1 |
YBL085W |
Protein involved in polar growth, functionally redundant with Boi2p |
physical |
1 |
1 |
1 |
Two-hybrid |
LPL1 |
YOR059C |
Phospholipase |
genetic |
1 |
1 |
1 |
Positive Genetic |
BBC1 |
YJL020C |
Protein possibly involved in assembly of actin patches |
physical |
1 |
1 |
1 |
Two-hybrid |
IRA2 |
YOL081W |
GTPase-activating protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSR2 |
YPR030W |
Nuclear ubiquitin protein ligase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ATG17 |
YLR423C |
Scaffold protein responsible for phagophore assembly site organization |
physical |
1 |
1 |
1 |
Two-hybrid |
BUB2 |
YMR055C |
Mitotic exit network regulator |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
CAF120 |
YNL278W |
Part of the CCR4-NOT transcriptional regulatory complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DMC1 |
YER179W |
Meiosis-specific recombinase required for double-strand break repair |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC20 |
YGL116W |
Activator of anaphase-promoting complex/cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCT3 |
YJL014W |
Subunit of the cytosolic chaperonin Cct ring complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KNS1 |
YLL019C |
Protein kinase involved in negative regulation of PolIII transcription |
physical |
1 |
1 |
1 |
Two-hybrid |
CDC37 |
YDR168W |
Essential Hsp90p co-chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
GLE1 |
YDL207W |
Cytoplasmic nucleoporin required for polyadenylated mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KEL2 |
YGR238C |
Protein that negatively regulates mitotic exit |
physical |
1 |
1 |
1 |
Two-hybrid |
FAL1 |
YDR021W |
Nucleolar protein required for maturation of 18S rRNA |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF2 |
YGR092W |
Ser/Thr kinase involved in transcription and stress response |
genetic |
1 |
1 |
1 |
Positive Genetic |
MMS22 |
YLR320W |
Subunit of E3 ubiquitin ligase complex involved in replication repair |
genetic |
1 |
1 |
1 |
Positive Genetic |
DAD1 |
YDR016C |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
ARP1 |
YHR129C |
Actin-related protein of the dynactin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
INO2 |
YDR123C |
Transcription factor |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOB2 |
YFL034C-B |
Activator of Cbk1p kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSB2 |
YGR014W |
Mucin family member involved in various signaling pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
MSH5 |
YDL154W |
Protein of the MutS family |
physical |
1 |
1 |
1 |
Two-hybrid |
COG2 |
YGR120C |
Essential component of the conserved oligomeric Golgi complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC19 |
YDR201W |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC105 |
YGL093W |
Subunit of a kinetochore-microtubule binding complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC2 |
YFR031C |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
YLR456W |
YLR456W |
Protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SPA2 |
YLL021W |
Component of the polarisome |
physical |
1 |
1 |
1 |
Two-hybrid |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
physical |
1 |
1 |
1 |
Co-purification |
YPK3 |
YBR028C |
AGC kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
YDL199C |
YDL199C |
Putative transporter |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VAC7 |
YNL054W |
Integral vacuolar membrane protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PTK2 |
YJR059W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
UBC9 |
YDL064W |
SUMO-conjugating enzyme involved in the Smt3p conjugation pathway |
physical |
1 |
1 |
1 |
Two-hybrid |
UFD1 |
YGR048W |
Substrate-recruiting cofactor of the Cdc48p-Npl4p-Ufd1p segregase |
physical |
1 |
1 |
1 |
Two-hybrid |
NIS1 |
YNL078W |
Protein involved in axial bud site selection |
physical |
1 |
1 |
1 |
Two-hybrid |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
1 |
1 |
1 |
Two-hybrid |
NFI1 |
YOR156C |
SUMO E3 ligase |
physical |
1 |
1 |
1 |
Two-hybrid |
SWI1 |
YPL016W |
Subunit of the SWI/SNF chromatin remodeling complex |
physical |
1 |
1 |
1 |
Two-hybrid |
YBP2 |
YGL060W |
Central kinetochore associated protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PEX13 |
YLR191W |
Peroxisomal importomer complex component |
physical |
1 |
1 |
1 |
Two-hybrid |
SHO1 |
YER118C |
Transmembrane osmosensor for filamentous growth and HOG pathways |
physical |
1 |
1 |
1 |
Two-hybrid |
SLA1 |
YBL007C |
Cytoskeletal protein binding protein |
physical |
1 |
1 |
1 |
Two-hybrid |
STU1 |
YBL034C |
Microtubule plus-end-tracking non-motor protein |
physical |
1 |
1 |
1 |
Co-localization |
SHE3 |
YBR130C |
Protein adaptor between Myo4p and the She2p-mRNA complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
VMA1 |
YDL185W |
Subunit A of the V1 peripheral membrane domain of V-ATPase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
TIF3 |
YPR163C |
Translation initiation factor eIF-4B |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMI1 |
YGR229C |
Protein involved in the regulation of cell wall synthesis |
physical |
1 |
1 |
1 |
Two-hybrid |
VAB2 |
YEL005C |
Subunit of the BLOC-1 complex involved in endosomal maturation |
physical |
1 |
1 |
1 |
Two-hybrid |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
SEC2 |
YNL272C |
Guanyl-nucleotide exchange factor for the small G-protein Sec4p |
physical |
1 |
1 |
1 |
Two-hybrid |
SMT3 |
YDR510W |
Ubiquitin-like protein of the SUMO family |
physical |
1 |
1 |
1 |
PCA |
UBR2 |
YLR024C |
Cytoplasmic ubiquitin-protein ligase (E3) |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSE1 |
YPL106C |
ATPase component of heat shock protein Hsp90 chaperone complex |
genetic |
1 |
1 |
1 |
Phenotypic Enhancement |
SSA1 |
YAL005C |
ATPase involved in protein folding and NLS-directed nuclear transport |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
SSA2 |
YLL024C |
HSP70 family ATP-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
RPB3 |
YIL021W |
RNA polymerase II third largest subunit B44 |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SLX5 |
YDL013W |
Subunit of the Slx5-Slx8 SUMO-targeted Ub ligase (STUbL) complex |
physical |
1 |
1 |
1 |
Two-hybrid |
SIS1 |
YNL007C |
Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUB1 |
YNL016W |
Poly (A)+ RNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SMC1 |
YFL008W |
Subunit of the multiprotein cohesin complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
UFD2 |
YDL190C |
Ubiquitin (Ub) chain assembly factor (E4) |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
TTI2 |
YJR136C |
Subunit of the ASTRA complex, involved in chromatin remodeling |
genetic |
1 |
1 |
1 |
Positive Genetic |
SLI15 |
YBR156C |
Subunit of the conserved chromosomal passenger complex (CPC) |
genetic |
1 |
1 |
1 |
Positive Genetic |
TIP20 |
YGL145W |
Peripheral membrane protein required for COPI vesicle fusion to the ER |
genetic |
1 |
1 |
1 |
Positive Genetic |
YKT6 |
YKL196C |
Vesicle membrane protein (v-SNARE) with acyltransferase activity |
genetic |
1 |
1 |
1 |
Positive Genetic |
SCS7 |
YMR272C |
Sphingolipid alpha-hydroxylase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YAR1 |
YPL239W |
Nucleocytoplasmic shuttling assembly chaperone |
genetic |
1 |
1 |
1 |
Positive Genetic |
VPS71 |
YML041C |
Nucleosome-binding component of the SWR1 complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
SNF2 |
YOR290C |
Catalytic subunit of the SWI/SNF chromatin remodeling complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
REB1 |
YBR049C |
RNA polymerase I enhancer binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC18 |
YBR080C |
AAA ATPase and SNARE disassembly chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
YRB1 |
YDR002W |
Ran GTPase binding protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PCF11 |
YDR228C |
mRNA 3' end processing factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRP101 |
YDR292C |
Signal recognition particle (SRP) receptor alpha subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC20 |
YDR498C |
Membrane glycoprotein v-SNARE |
genetic |
1 |
1 |
1 |
Negative Genetic |
NTF2 |
YER009W |
Nuclear envelope protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
TSC11 |
YER093C |
Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPT6 |
YGR116W |
Nucleosome remodeling protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP57 |
YGR119C |
FG-nucleoporin component of central core of the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
NOP19 |
YGR251W |
Ribosome biogenesis factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPO21 |
YDL140C |
RNA polymerase II largest subunit B220 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN5 |
YDL147W |
Subunit of the CSN and 26S proteasome lid complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRP1 |
YDR087C |
Essential evolutionarily conserved nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNU56 |
YDR240C |
Component of U1 snRNP required for mRNA splicing via spliceosome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP192 |
YJL039C |
Essential subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP85 |
YJR042W |
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAM18 |
YLR008C |
Subunit of the import motor (PAM complex) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SMC4 |
YLR086W |
Subunit of the condensin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UTP15 |
YMR093W |
Nucleolar protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPC34 |
YNR003C |
RNA polymerase III subunit C34 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RAT1 |
YOR048C |
Nuclear 5' to 3' single-stranded RNA exonuclease |
genetic |
1 |
1 |
1 |
Negative Genetic |
NIP7 |
YPL211W |
Nucleolar protein required for 60S ribosome subunit biogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
TAP42 |
YMR028W |
Essential protein involved in the TOR signaling pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
PSE1 |
YMR308C |
Karyopherin/importin that interacts with the nuclear pore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB11 |
YOL005C |
RNA polymerase II subunit B12.5 |
genetic |
1 |
1 |
1 |
Negative Genetic |
RFC4 |
YOL094C |
Subunit of heteropentameric Replication factor C (RF-C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPB10 |
YOR210W |
RNA polymerase subunit ABC10-beta |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC63 |
YOR254C |
Essential subunit of Sec63 complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPT4 |
YOR259C |
ATPase of the 19S regulatory particle of the 26S proteasome |
genetic |
1 |
1 |
1 |
Negative Genetic |
NSL1 |
YPL233W |
Essential component of the MIND kinetochore complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGV1 |
YPR161C |
Cyclin (Bur2p)-dependent protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SSH1 |
YBR283C |
Subunit of the Ssh1 translocon complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
UME6 |
YDR207C |
Rpd3L histone deacetylase complex subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEM1 |
YDR363W-A |
19S proteasome regulatory particle lid subcomplex component |
genetic |
1 |
1 |
1 |
Negative Genetic |
PPM1 |
YDR435C |
Carboxyl methyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLX8 |
YER116C |
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAC10 |
YGR078C |
Part of the heteromeric co-chaperone GimC/prefoldin complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPN10 |
YHR200W |
Proteasome polyubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
YNL140C |
YNL140C |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS8A |
YBL072C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
SWF1 |
YDR126W |
Palmitoyltransferase that acts on transmembrane proteins |
genetic |
1 |
1 |
1 |
Negative Genetic |
PUF6 |
YDR496C |
Pumilio-homology domain protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMR1 |
YGL167C |
High affinity Ca2+/Mn2+ P-type ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPO74 |
YGL170C |
Component of the meiotic outer plaque of the spindle pole body |
genetic |
1 |
1 |
1 |
Negative Genetic |
PIR5 |
YJL160C |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKL069W |
YKL069W |
Methionine-R-sulfoxide reductase |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPL22A |
YLR061W |
Ribosomal 60S subunit protein L22A |
genetic |
1 |
1 |
1 |
Negative Genetic |
SST2 |
YLR452C |
GTPase-activating protein for Gpa1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM6 |
YML047C |
Potassium transporter that mediates K+ influx |
genetic |
1 |
1 |
1 |
Negative Genetic |
UBA3 |
YPR066W |
Protein that activates Rub1p (NEDD8) before neddylation |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS8 |
YAL002W |
Membrane-binding component of the CORVET complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
YAR029W |
YAR029W |
Member of DUP240 gene family but contains no transmembrane domains |
genetic |
1 |
1 |
1 |
Negative Genetic |
SHP1 |
YBL058W |
UBX domain-containing substrate adaptor for Cdc48p |
genetic |
1 |
1 |
1 |
Negative Genetic |
NUP170 |
YBL079W |
Subunit of inner ring of nuclear pore complex (NPC) |
genetic |
1 |
1 |
1 |
Negative Genetic |
SUS1 |
YBR111W-A |
Global transcriptional regulator, component of SAGA, TREX-2 complexes |
genetic |
1 |
1 |
1 |
Negative Genetic |
YBR285W |
YBR285W |
Putative protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
YCR023C |
YCR023C |
Vacuolar membrane protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
PMP3 |
YDR276C |
Small plasma membrane protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
NHX1 |
YDR456W |
Na+/H+ and K+/H+ exchanger |
genetic |
1 |
1 |
1 |
Negative Genetic |
SPF1 |
YEL031W |
P-type ATPase, ion transporter of the ER membrane |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS45 |
YGL095C |
Protein of the Sec1p/Munc-18 family |
genetic |
1 |
1 |
1 |
Negative Genetic |
ZUO1 |
YGR285C |
Ribosome-associated chaperone |
genetic |
1 |
1 |
1 |
Negative Genetic |
PTH1 |
YHR189W |
One of two mitochondrially-localized peptidyl-tRNA hydrolases |
genetic |
1 |
1 |
1 |
Negative Genetic |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
PRM5 |
YIL117C |
Pheromone-regulated protein, predicted to have 1 transmembrane segment |
genetic |
1 |
1 |
1 |
Negative Genetic |
PEP8 |
YJL053W |
Vacuolar protein component of the retromer |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS35 |
YJL154C |
Endosomal subunit of membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS13 |
YLL040C |
Lipid transport protein involved in prospore membrane morphogenesis |
genetic |
1 |
1 |
1 |
Negative Genetic |
SRN2 |
YLR119W |
Component of the ESCRT-I complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS9 |
YML097C |
Guanine nucleotide exchange factor (GEF) and ubiquitin receptor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLM2 |
YNL047C |
Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
SLA2 |
YNL243W |
Adaptor protein that links actin to clathrin and endocytosis |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS27 |
YNR006W |
Endosomal protein that forms a complex with Hse1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS17 |
YOR132W |
Subunit of the membrane-associated retromer complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
PDE2 |
YOR360C |
High-affinity cyclic AMP phosphodiesterase |
genetic |
1 |
1 |
1 |
Negative Genetic |
VPS30 |
YPL120W |
Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II |
genetic |
1 |
1 |
1 |
Negative Genetic |
RPS6B |
YBR181C |
Protein component of the small (40S) ribosomal subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
RRD2 |
YPL152W |
Peptidyl-prolyl cis/trans-isomerase |
genetic |
1 |
1 |
1 |
Negative Genetic |
TGS1 |
YPL157W |
Trimethyl guanosine synthase, conserved nucleolar methyl transferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNT1 |
YCR033W |
Set3C histone deacetylase scaffold |
genetic |
1 |
1 |
1 |
Negative Genetic |
PAT1 |
YCR077C |
Deadenylation-dependent mRNA-decapping factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
SEC12 |
YNR026C |
Guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
YKE2 |
YLR200W |
Subunit of the heterohexameric Gim/prefoldin protein complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
RIO1 |
YOR119C |
Serine kinase involved in cell cycle regulation and rDNA integrity |
genetic |
1 |
1 |
1 |
Negative Genetic |
SGS1 |
YMR190C |
RecQ family nucleolar DNA helicase |
genetic |
1 |
1 |
1 |
Positive Genetic |
YTA7 |
YGR270W |
Chromatin-binding ATPase that regulates histone gene expression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
ADY3 |
YDL239C |
Protein required for spore wall formation |
physical |
1 |
1 |
1 |
Two-hybrid |
CUB1 |
YPL260W |
Conserved fungal gene linked to DNA repair and proteasome function |
physical |
1 |
1 |
1 |
Two-hybrid |
COG4 |
YPR105C |
Essential component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
APC5 |
YOR249C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
CDC27 |
YBL084C |
Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C) |
genetic |
1 |
1 |
1 |
Negative Genetic |
COG5 |
YNL051W |
Component of the conserved oligomeric Golgi complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
AMD1 |
YML035C |
AMP deaminase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
physical |
1 |
1 |
1 |
Co-localization |
CSE4 |
YKL049C |
Centromeric histone H3-like protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
BUB1 |
YGR188C |
Protein kinase involved in the cell cycle checkpoint into anaphase |
genetic |
1 |
1 |
1 |
Negative Genetic |
DBF4 |
YDR052C |
Regulatory subunit of Cdc7p-Dbf4p kinase complex |
genetic |
1 |
1 |
1 |
Positive Genetic |
DBP5 |
YOR046C |
Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family |
genetic |
1 |
1 |
1 |
Negative Genetic |
MEX67 |
YPL169C |
Poly(A)RNA binding protein involved in nuclear mRNA export |
genetic |
1 |
1 |
1 |
Negative Genetic |
MPS1 |
YDL028C |
Dual-specificity kinase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CCZ1 |
YBR131W |
Subunit of a heterodimeric guanine nucleotide exchange factor (GEF) |
genetic |
1 |
1 |
1 |
Negative Genetic |
JNM1 |
YMR294W |
Component of the yeast dynactin complex |
physical |
1 |
1 |
1 |
Two-hybrid |
CCP1 |
YKR066C |
Mitochondrial cytochrome-c peroxidase |
genetic |
1 |
1 |
1 |
Negative Genetic |
GYP1 |
YOR070C |
Cis-golgi GTPase-activating protein (GAP) for yeast Rabs |
genetic |
1 |
1 |
1 |
Positive Genetic |
MCA1 |
YOR197W |
Ca2+-dependent cysteine protease |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KEX2 |
YNL238W |
Kexin, a subtilisin-like protease (proprotein convertase) |
genetic |
1 |
1 |
1 |
Negative Genetic |
BET4 |
YJL031C |
Alpha subunit of Type II geranylgeranyltransferase |
genetic |
1 |
1 |
1 |
Positive Genetic |
MOG1 |
YJR074W |
Conserved nuclear protein that interacts with GTP-Gsp1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
AIM44 |
YPL158C |
Regulator of Cdc42p and Rho1p |
genetic |
1 |
1 |
1 |
Negative Genetic |
CNN1 |
YFR046C |
Kinetochore protein |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
IZH4 |
YOL101C |
Membrane protein involved in zinc ion homeostasis |
genetic |
1 |
1 |
1 |
Negative Genetic |
HCM1 |
YCR065W |
Forkhead transcription factor |
genetic |
1 |
1 |
1 |
Negative Genetic |
BTS1 |
YPL069C |
Geranylgeranyl diphosphate synthase (GGPPS) |
genetic |
1 |
1 |
1 |
Positive Genetic |
ALG1 |
YBR110W |
Mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
ERG2 |
YMR202W |
C-8 sterol isomerase |
genetic |
1 |
1 |
1 |
Positive Genetic |
ERG7 |
YHR072W |
Lanosterol synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
HSK3 |
YKL138C-A |
Essential subunit of the Dam1 complex (aka DASH complex) |
physical |
1 |
1 |
1 |
Two-hybrid |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Negative Genetic |
HRQ1 |
YDR291W |
3'-5' DNA helicase of the conserved RecQ family |
genetic |
1 |
1 |
1 |
Positive Genetic |
ELF1 |
YKL160W |
Transcription elongation factor with a conserved zinc finger domain |
genetic |
1 |
1 |
1 |
Negative Genetic |
APS1 |
YLR170C |
Small subunit of the clathrin-associated adaptor complex AP-1 |
genetic |
1 |
1 |
1 |
Negative Genetic |
ATG33 |
YLR356W |
Mitochondrial mitophagy-specific protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MDM36 |
YPR083W |
Mitochondrial protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
MRPS17 |
YMR188C |
Mitochondrial ribosomal protein of the small subunit |
genetic |
1 |
1 |
1 |
Negative Genetic |
KRE28 |
YDR532C |
Subunit of a kinetochore-microtubule binding complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
EOS1 |
YNL080C |
Protein involved in N-glycosylation |
genetic |
1 |
1 |
1 |
Positive Genetic |
KTR1 |
YOR099W |
Alpha-1,2-mannosyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
CEM1 |
YER061C |
Mitochondrial beta-keto-acyl synthase |
genetic |
1 |
1 |
1 |
Negative Genetic |
FRT1 |
YOR324C |
Tail-anchored ER membrane protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
ALG2 |
YGL065C |
Mannosyltransferase in the N-linked glycosylation pathway |
genetic |
1 |
1 |
1 |
Negative Genetic |
ECM34 |
YHL043W |
Protein of unknown function |
genetic |
1 |
1 |
1 |
Negative Genetic |
MSS2 |
YDL107W |
Peripherally bound inner membrane protein of the mitochondrial matrix |
genetic |
1 |
1 |
1 |
Negative Genetic |
IRC15 |
YPL017C |
Microtubule associated protein |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI8 |
YDR331W |
Catalytic subunit of the ER membrane GPI transamidase complex |
genetic |
1 |
1 |
1 |
Negative Genetic |
GPI11 |
YDR302W |
ER membrane protein involved in a late step of GPI anchor assembly |
genetic |
1 |
1 |
1 |
Negative Genetic |
ICT1 |
YLR099C |
Lysophosphatidic acid acyltransferase |
genetic |
1 |
1 |
1 |
Negative Genetic |
MIN3 |
YMR182W-A |
Mitochondrial protein of unknown function |
genetic |
1 |
1 |
1 |
Positive Genetic |