Standard name Systematic name Name description Description
STV1 YMR054W Subunit a of the vacuolar-ATPase V0 domain Subunit a of the vacuolar-ATPase V0 domain; encodes one of two isoforms, located in both Golgi and endosomal V-ATPase complexes while VPH1 encodes the second isoform and is located in vacuolar V-ATPase complexes; interaction with PI(4)P is required for efficient localization and function of Stv1-containing V-ATPases
Visualize the interactome of STV1
Links to external databases:
SGD   |   KEGG   |  

Cell cycle phase and timing of transcription peak

Cell cycle phase Time (min)

CYCLoPs localization & abundance

WT1 WT2 WT3
Cytoplasm 0.091 0.086 0.091
Endosome 0.355 NaN 0.433
Golgi 0.064 0.058 0.052
Mito 0.493 0.835 0.329
Peroxisome 0.080 NaN 0.179
SpindlePole 0.100 NaN 0.202
Vac/Vac Memb 0.086 NaN NaN
Cort. Patches NaN 0.094 NaN
ER NaN 0.065 NaN

GFP localization & abundance

GFP localization GFP abundance
early Golgi, late Golgi 1080

GO term count

Metabolism Cell cycle Cell division Signal transduction DNA replication
STV1 0 0 0 0 0

Enzyme information

Catalyzed reactions in Yeast8
r_1085 (V-ATPase, Golgi)

List of interactors

Use the search utility to find the interactor you are looking for. By clicking the column headers the table will be sorted on that column. Use shift+click to sort on multiple columns. Default sorting is on number of experiments, number of unique methods and the number of publications, and alphabetical on standard name, in that order.
Standard name Systematic name Name description Type #Experiments #Methods #Publications Evidence
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain genetic 13 6 10 Dosage Rescue, Negative Genetic, Negative Genetic, Synthetic Growth Defect, Phenotypic Enhancement, Phenotypic Enhancement, Synthetic Lethality, Dosage Rescue, Negative Genetic, Synthetic Growth Defect, Synthetic Rescue, Negative Genetic, Negative Genetic
RIC1 YLR039C Protein involved in retrograde transport to the cis-Golgi network genetic 7 2 6 Negative Genetic, Negative Genetic, Synthetic Growth Defect, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
YPT6 YLR262C Rab family GTPase genetic 5 2 5 Synthetic Lethality, Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
RGP1 YDR137W Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) genetic 4 1 3 Negative Genetic, Negative Genetic, Negative Genetic, Negative Genetic
SCS7 YMR272C Sphingolipid alpha-hydroxylase genetic 4 1 3 Positive Genetic, Positive Genetic, Positive Genetic, Positive Genetic
VMA1 YDL185W Subunit A of the V1 peripheral membrane domain of V-ATPase physical 3 3 3 Two-hybrid, Affinity Capture-Western, Co-purification
PMA2 YPL036W Plasma membrane H+-ATPase genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
COG7 YGL005C Component of the conserved oligomeric Golgi complex genetic 3 1 2 Negative Genetic, Negative Genetic, Negative Genetic
PMR1 YGL167C High affinity Ca2+/Mn2+ P-type ATPase genetic 3 1 2 Positive Genetic, Positive Genetic, Positive Genetic
RAV1 YJR033C Subunit of RAVE complex (Rav1p, Rav2p, Skp1p) genetic 3 3 1 Dosage Rescue, Phenotypic Suppression, Synthetic Growth Defect
VMA13 YPR036W Subunit H of the V1 peripheral membrane domain of V-ATPase physical 2 2 2 Affinity Capture-Western, PCA
VMA6 YLR447C Subunit d of the V0 integral membrane domain of V-ATPase physical 2 2 2 Affinity Capture-Western, Co-purification
PUF3 YLL013C Protein of the mitochondrial outer surface physical 2 1 2 Affinity Capture-RNA, Affinity Capture-RNA
EFM1 YHL039W Lysine methyltransferase genetic 2 1 2 Negative Genetic, Negative Genetic
MNS1 YJR131W Alpha-1,2-mannosidase genetic 2 1 2 Negative Genetic, Negative Genetic
NST1 YNL091W Translational inhibitor and suppressor of proteasome-assembly defects genetic 2 1 2 Negative Genetic, Negative Genetic
EMP47 YFL048C Integral membrane component of ER-derived COPII-coated vesicles genetic 2 1 2 Negative Genetic, Negative Genetic
SMI1 YGR229C Protein involved in the regulation of cell wall synthesis genetic 2 1 2 Negative Genetic, Negative Genetic
SUR1 YPL057C Mannosylinositol phosphorylceramide (MIPC) synthase catalytic subunit genetic 2 1 2 Negative Genetic, Negative Genetic
SYS1 YJL004C Integral membrane protein of the Golgi genetic 2 1 2 Negative Genetic, Negative Genetic
IXR1 YKL032C Transcriptional repressor that regulates hypoxic genes during normoxia genetic 2 1 2 Negative Genetic, Negative Genetic
ERG5 YMR015C C-22 sterol desaturase genetic 2 1 2 Negative Genetic, Negative Genetic
ESA1 YOR244W Catalytic subunit of the histone acetyltransferase complex (NuA4) genetic 2 1 1 Synthetic Growth Defect, Synthetic Growth Defect
APL5 YPL195W Delta adaptin-like subunit of the clathrin associated protein complex genetic 2 1 1 Negative Genetic, Negative Genetic
APL6 YGR261C Beta3-like subunit of the yeast AP-3 complex genetic 2 1 1 Negative Genetic, Negative Genetic
CSE2 YNR010W Subunit of the RNA polymerase II mediator complex genetic 2 1 1 Negative Genetic, Negative Genetic
DIA4 YHR011W Probable mitochondrial seryl-tRNA synthetase physical 2 1 1 Two-hybrid, Two-hybrid
FAR8 YMR029C Protein involved in recovery from arrest in response to pheromone genetic 2 1 1 Negative Genetic, Negative Genetic
APM3 YBR288C Mu3-like subunit of the clathrin associated protein complex (AP-3) genetic 2 1 1 Negative Genetic, Negative Genetic
SWA2 YDR320C Auxilin-like protein involved in vesicular transport genetic 2 1 1 Negative Genetic, Negative Genetic
OPI3 YJR073C Methylene-fatty-acyl-phospholipid synthase genetic 2 1 1 Negative Genetic, Negative Genetic
INO2 YDR123C Transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
PHO2 YDL106C Homeobox transcription factor regulation 1 1 1 chromatin immunoprecipitation-chip evidence
ARL1 YBR164C Soluble GTPase with a role in regulation of membrane traffic genetic 1 1 1 Synthetic Growth Defect
NUT1 YGL151W Component of the RNA polymerase II mediator complex genetic 1 1 1 Negative Genetic
CCR4 YAL021C Component of the CCR4-NOT transcriptional complex physical 1 1 1 Affinity Capture-RNA
NAB2 YGL122C Nuclear polyadenylated RNA-binding protein physical 1 1 1 Affinity Capture-RNA
CDC3 YLR314C Component of the septin ring that is required for cytokinesis physical 1 1 1 Two-hybrid
GLO3 YER122C ADP-ribosylation factor GTPase activating protein (ARF GAP) genetic 1 1 1 Negative Genetic
ERV25 YML012W Member of the p24 family involved in ER to Golgi transport physical 1 1 1 PCA
DYN1 YKR054C Cytoplasmic heavy chain dynein physical 1 1 1 Two-hybrid
ISW1 YBR245C ATPase subunit of imitation-switch (ISWI) class chromatin remodelers physical 1 1 1 Affinity Capture-RNA
END3 YNL084C EH domain-containing protein involved in endocytosis physical 1 1 1 Two-hybrid
HSC82 YMR186W Cytoplasmic chaperone of the Hsp90 family genetic 1 1 1 Synthetic Growth Defect
MYO1 YHR023W Type II myosin heavy chain physical 1 1 1 Two-hybrid
HSP82 YPL240C Hsp90 chaperone genetic 1 1 1 Synthetic Growth Defect
PGD1 YGL025C Subunit of the RNA polymerase II mediator complex physical 1 1 1 Two-hybrid
SEC13 YLR208W Structural component of 3 complexes physical 1 1 1 Affinity Capture-MS
SEC26 YDR238C Essential beta-coat protein of the COPI coatomer genetic 1 1 1 Negative Genetic
SEC23 YPR181C GTPase-activating protein, stimulates the GTPase activity of Sar1p physical 1 1 1 Affinity Capture-MS
RPT5 YOR117W ATPase of the 19S regulatory particle of the 26S proteasome physical 1 1 1 Two-hybrid
SBP1 YHL034C Protein that binds eIF4G and has a role in repression of translation physical 1 1 1 Affinity Capture-RNA
ATG9 YDL149W Transmembrane protein involved in forming Cvt and autophagic vesicles physical 1 1 1 Affinity Capture-MS
ARF1 YDL192W ADP-ribosylation factor physical 1 1 1 Affinity Capture-Western
KOG1 YHR186C Subunit of TORC1 physical 1 1 1 Two-hybrid
GET1 YGL020C Subunit of the GET complex genetic 1 1 1 Negative Genetic
PHO81 YGR233C Cyclin-dependent kinase (CDK) inhibitor genetic 1 1 1 Negative Genetic
AIP1 YMR092C Actin cortical patch component genetic 1 1 1 Negative Genetic
SGS1 YMR190C RecQ family nucleolar DNA helicase genetic 1 1 1 Positive Genetic
SEG1 YMR086W Component of eisosome required for proper eisosome assembly genetic 1 1 1 Negative Genetic
GDT1 YBR187W Calcium and manganese transporter with higher affinity for Ca2+ genetic 1 1 1 Synthetic Rescue
STE4 YOR212W G protein beta subunit physical 1 1 1 Two-hybrid
PMI40 YER003C Mannose-6-phosphate isomerase genetic 1 1 1 Negative Genetic
ESS1 YJR017C Peptidylprolyl-cis/trans-isomerase (PPIase) genetic 1 1 1 Synthetic Growth Defect
BUD27 YFL023W Unconventional prefoldin protein involved in translation initiation physical 1 1 1 Two-hybrid
NDC80 YIL144W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
NUF2 YOL069W Component of the kinetochore-associated Ndc80 complex physical 1 1 1 Two-hybrid
MMR1 YLR190W Phosphorylated protein of the mitochondrial outer membrane physical 1 1 1 Two-hybrid
PKC1 YBL105C Protein serine/threonine kinase physical 1 1 1 Two-hybrid
RIM101 YHL027W Cys2His2 zinc-finger transcriptional repressor genetic 1 1 1 Negative Genetic
ATG27 YJL178C Type I membrane protein involved in autophagy and the Cvt pathway physical 1 1 1 Affinity Capture-MS
SFL1 YOR140W Transcriptional repressor and activator genetic 1 1 1 Negative Genetic
RPS8A YBL072C Protein component of the small (40S) ribosomal subunit genetic 1 1 1 Negative Genetic
ATG23 YLR431C Peripheral membrane protein required for autophagy and CVT physical 1 1 1 Affinity Capture-MS
ATG8 YBL078C Ub-like protein physical 1 1 1 Affinity Capture-MS
BFR1 YOR198C Component of mRNP complexes associated with polyribosomes physical 1 1 1 Affinity Capture-RNA
BIK1 YCL029C Microtubule-associated protein physical 1 1 1 Two-hybrid
MPS2 YGL075C Essential membrane protein localized at nuclear envelope and SPBs physical 1 1 1 Two-hybrid
MGM1 YOR211C Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p genetic 1 1 1 Negative Genetic
CNM67 YNL225C Component of the spindle pole body outer plaque physical 1 1 1 Two-hybrid
SEC24 YIL109C Component of the Sec23p-Sec24p heterodimer of the COPII vesicle coat physical 1 1 1 Affinity Capture-MS
SPO21 YOL091W Component of the meiotic outer plaque of the spindle pole body physical 1 1 1 Two-hybrid
VMA2 YBR127C Subunit B of V1 peripheral membrane domain of vacuolar H+-ATPase physical 1 1 1 Affinity Capture-Western
VMA5 YKL080W Subunit C of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-Western
VMA8 YEL051W Subunit D of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-Western
VMA4 YOR332W Subunit E of the V1 domain of the vacuolar H+-ATPase (V-ATPase) physical 1 1 1 Affinity Capture-Western
VMA7 YGR020C Subunit F of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-Western
VMA10 YHR039C-A Subunit G of the V1 peripheral membrane domain of V-ATPase physical 1 1 1 Affinity Capture-Western
TLG2 YOL018C Syntaxin-like t-SNARE physical 1 1 1 Co-purification
VPH1 YOR270C Subunit a of the vacuolar-ATPase V0 domain physical 1 1 1 Affinity Capture-Western
ZRC1 YMR243C Vacuolar membrane zinc transporter physical 1 1 1 PCA
YKE2 YLR200W Subunit of the heterohexameric Gim/prefoldin protein complex physical 1 1 1 Two-hybrid
YAF9 YNL107W Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes physical 1 1 1 Two-hybrid
TEA1 YOR337W Ty1 enhancer activator involved in Ty enhancer-mediated transcription physical 1 1 1 Two-hybrid
VPS30 YPL120W Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II physical 1 1 1 Affinity Capture-MS
VPS15 YBR097W Serine/threonine protein kinase involved in vacuolar protein sorting physical 1 1 1 Affinity Capture-MS
VPS34 YLR240W Phosphatidylinositol (PI) 3-kinase that synthesizes PI-3-phosphate physical 1 1 1 Affinity Capture-MS
VMA9 YCL005W-A Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex physical 1 1 1 Co-purification
VMA11 YPL234C Vacuolar ATPase V0 domain subunit c' physical 1 1 1 Co-purification
VMA16 YHR026W Subunit c'' of the vacuolar ATPase physical 1 1 1 Co-purification
VMA3 YEL027W Proteolipid subunit c of the V0 domain of vacuolar H(+)-ATPase physical 1 1 1 Co-purification
UGX2 YDL169C Protein of unknown function genetic 1 1 1 Negative Genetic
YGL235W YGL235W Putative protein of unknown function genetic 1 1 1 Negative Genetic
VMA21 YGR105W Integral membrane protein required for V-ATPase function genetic 1 1 1 Synthetic Growth Defect
TAT1 YBR069C Amino acid transporter for valine, leucine, isoleucine, and tyrosine genetic 1 1 1 Negative Genetic
YPK2 YMR104C AGC-type S/T protein kinase genetic 1 1 1 Negative Genetic
VPS16 YPL045W Subunit of the HOPS and the CORVET complexes genetic 1 1 1 Negative Genetic
UBP13 YBL067C Ubiquitin-specific protease that cleaves Ub-protein fusions genetic 1 1 1 Negative Genetic
TOS2 YGR221C Protein involved in localization of Cdc24p to the site of bud growth genetic 1 1 1 Negative Genetic
VPS53 YJL029C Component of the GARP (Golgi-associated retrograde protein) complex genetic 1 1 1 Negative Genetic
VPS35 YJL154C Endosomal subunit of membrane-associated retromer complex genetic 1 1 1 Negative Genetic
ARL3 YPL051W ARF-like small GTPase of the RAS superfamily genetic 1 1 1 Negative Genetic
SGF11 YPL047W Integral subunit of SAGA histone acetyltransferase complex genetic 1 1 1 Negative Genetic
SSB1 YDL229W Cytoplasmic ATPase that is a ribosome-associated molecular chaperone physical 1 1 1 Affinity Capture-MS
PAC1 YOR269W Regulator of dynein, involved in intracellular transport physical 1 1 1 Two-hybrid
PAC1 YOR269W Regulator of dynein, involved in intracellular transport genetic 1 1 1 Negative Genetic
PSG1 YKL077W Protein that promotes the transport and maturation of Pma1 with Exp1 physical 1 1 1 Affinity Capture-MS
HRQ1 YDR291W 3'-5' DNA helicase of the conserved RecQ family genetic 1 1 1 Positive Genetic
BUL2 YML111W Alpha-arrestin, component of the Rsp5p E3-ubiquitin ligase complex physical 1 1 1 Affinity Capture-MS
RIM8 YGL045W Protein involved in proteolytic activation of Rim101p genetic 1 1 1 Negative Genetic
SLX4 YLR135W Endonuclease involved in processing DNA genetic 1 1 1 Negative Genetic
HFD1 YMR110C Dehydrogenase involved in ubiquinone and sphingolipid metabolism genetic 1 1 1 Negative Genetic
PKR1 YMR123W V-ATPase assembly factor genetic 1 1 1 Synthetic Growth Defect
RTT107 YHR154W BRCA1 C-terminal domain protein needed for recovery from DNA damage genetic 1 1 1 Negative Genetic
SKY1 YMR216C SR protein kinase (SRPK) genetic 1 1 1 Negative Genetic
SMY1 YKL079W Kinesin-like myosin passenger-protein physical 1 1 1 Two-hybrid
SCH9 YHR205W AGC family protein kinase genetic 1 1 1 Synthetic Growth Defect
HUR1 YGL168W Protein with a role in DNA repair genetic 1 1 1 Positive Genetic
DNF2 YDR093W Aminophospholipid translocase (flippase) physical 1 1 1 PCA
FRE1 YLR214W Ferric reductase and cupric reductase physical 1 1 1 PCA
ILM1 YJR118C Protein of unknown function genetic 1 1 1 Negative Genetic
FRT1 YOR324C Tail-anchored ER membrane protein of unknown function physical 1 1 1 Two-hybrid
LAM4 YHR080C Sterol-binding protein that localizes to puncta in the cortical ER physical 1 1 1 Two-hybrid
IZH2 YOL002C Plasma membrane receptor for plant antifungal osmotin genetic 1 1 1 Synthetic Growth Defect
CDC1 YDR182W Putative mannose-ethanolamine phosphate phosphodiesterase genetic 1 1 1 Negative Genetic