SPC42 |
YKL042W |
Central plaque component of spindle pole body (SPB) |
physical |
11 |
3 |
7 |
Two-hybrid, Two-hybrid, Two-hybrid, FRET, FRET, FRET, Affinity Capture-MS, FRET, FRET, Two-hybrid, Two-hybrid |
SPC110 |
YDR356W |
Inner plaque spindle pole body (SPB) component |
physical |
5 |
3 |
4 |
Affinity Capture-Western, FRET, Co-purification, FRET, FRET |
SPC29 |
YPL124W |
Inner plaque spindle pole body (SPB) component |
physical |
4 |
1 |
2 |
FRET, FRET, FRET, FRET |
CNM67 |
YNL225C |
Component of the spindle pole body outer plaque |
physical |
3 |
3 |
3 |
Two-hybrid, FRET, Co-crystal Structure |
SPO21 |
YOL091W |
Component of the meiotic outer plaque of the spindle pole body |
physical |
3 |
2 |
3 |
Two-hybrid, Two-hybrid, FRET |
NUD1 |
YOR373W |
Mitotic exit network (MEN) scaffold protein |
physical |
3 |
2 |
2 |
Affinity Capture-Western, Affinity Capture-Western, Two-hybrid |
CMD1 |
YBR109C |
Calmodulin |
physical |
3 |
1 |
2 |
FRET, FRET, FRET |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
physical |
2 |
2 |
2 |
Affinity Capture-Western, Biochemical Activity |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
physical |
2 |
2 |
2 |
Affinity Capture-MS, Reconstituted Complex |
ESA1 |
YOR244W |
Catalytic subunit of the histone acetyltransferase complex (NuA4) |
physical |
2 |
2 |
2 |
Biochemical Activity, Affinity Capture-MS |
SRS2 |
YJL092W |
DNA helicase and DNA-dependent ATPase |
genetic |
2 |
2 |
2 |
Synthetic Growth Defect, Dosage Rescue |
ADY3 |
YDL239C |
Protein required for spore wall formation |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
MLP2 |
YIL149C |
Myosin-like protein associated with the nuclear envelope |
physical |
2 |
1 |
2 |
Affinity Capture-MS, Affinity Capture-MS |
MPT5 |
YGL178W |
mRNA-binding protein of the PUF family |
physical |
2 |
1 |
2 |
Affinity Capture-RNA, Affinity Capture-RNA |
AFI1 |
YOR129C |
Arf3p polarization-specific docking factor |
physical |
2 |
1 |
2 |
Two-hybrid, Two-hybrid |
CDC5 |
YMR001C |
Polo-like kinase required for mitotic exit |
genetic |
2 |
2 |
1 |
Synthetic Rescue, Dosage Rescue |
KIN3 |
YAR018C |
Nonessential serine/threonine protein kinase |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
YAF9 |
YNL107W |
Subunit of NuA4 histone H4 acetyltransferase and SWR1 complexes |
physical |
2 |
1 |
1 |
Two-hybrid, Two-hybrid |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
genetic |
2 |
1 |
1 |
Synthetic Growth Defect, Synthetic Growth Defect |
RPD3 |
YNL330C |
Histone deacetylase, component of both the Rpd3S and Rpd3L complexes |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
HDA1 |
YNL021W |
Catalytic subunit of class II HDA1 histone deacetylase complex |
genetic |
2 |
1 |
1 |
Dosage Lethality, Dosage Lethality |
FKH1 |
YIL131C |
Forkhead family transcription factor |
regulation |
1 |
1 |
1 |
chromatin immunoprecipitation-chip evidence |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
regulation |
1 |
1 |
1 |
quantitative mass spectrometry evidence |
ACT1 |
YFL039C |
Actin, structural protein in cytoskeleton |
genetic |
1 |
1 |
1 |
Synthetic Haploinsufficiency |
CCR4 |
YAL021C |
Component of the CCR4-NOT transcriptional complex |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
CDC14 |
YFR028C |
Protein phosphatase required for mitotic exit |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
CDC28 |
YBR160W |
Cyclin-dependent kinase (CDK) catalytic subunit |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BFA1 |
YJR053W |
Subunit of a two-component GTPase-activating protein, Bfa1p-Bub2p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CIN8 |
YEL061C |
Bipolar kinesin motor protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CDC15 |
YAR019C |
Hippo-like kinase of the Mitotic Exit Network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
CLB2 |
YPR119W |
B-type cyclin involved in cell cycle progression |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
BUD27 |
YFL023W |
Unconventional prefoldin protein involved in translation initiation |
physical |
1 |
1 |
1 |
Two-hybrid |
BIM1 |
YER016W |
Microtubule plus end-tracking protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
NUD1 |
YOR373W |
Mitotic exit network (MEN) scaffold protein |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ECM21 |
YBL101C |
Alpha-arrestin, ubiquitin ligase adaptor for Rsp5p |
physical |
1 |
1 |
1 |
Two-hybrid |
LGE1 |
YPL055C |
Protein involved in histone H2B ubiquitination |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
SAK1 |
YER129W |
Upstream serine/threonine kinase for the SNF1 complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MPC54 |
YOR177C |
Component of the meiotic outer plaque |
physical |
1 |
1 |
1 |
FRET |
PHO85 |
YPL031C |
Cyclin-dependent kinase |
physical |
1 |
1 |
1 |
Biochemical Activity |
SAN1 |
YDR143C |
Ubiquitin-protein ligase |
physical |
1 |
1 |
1 |
Two-hybrid |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
GIS2 |
YNL255C |
Translational activator for mRNAs with internal ribosome entry sites |
genetic |
1 |
1 |
1 |
Negative Genetic |
SNF1 |
YDR477W |
AMP-activated S/T protein kinase |
physical |
1 |
1 |
1 |
Reconstituted Complex |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
KIN4 |
YOR233W |
Serine/threonine protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ERP3 |
YDL018C |
Protein with similarity to Emp24p and Erv25p |
physical |
1 |
1 |
1 |
Two-hybrid |
COY1 |
YKL179C |
Golgi membrane protein with similarity to mammalian CASP |
physical |
1 |
1 |
1 |
Two-hybrid |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
physical |
1 |
1 |
1 |
Two-hybrid |
DYN1 |
YKR054C |
Cytoplasmic heavy chain dynein |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
SPC24 |
YMR117C |
Component of the kinetochore-associated Ndc80 complex |
physical |
1 |
1 |
1 |
Two-hybrid |
IPI3 |
YNL182C |
Component of the Rix1 complex and pre-replicative complexes (pre-RCs) |
physical |
1 |
1 |
1 |
Two-hybrid |
LUC7 |
YDL087C |
Essential protein associated with the U1 snRNP complex |
physical |
1 |
1 |
1 |
Two-hybrid |
NOT3 |
YIL038C |
Component of the CCR4-NOT core complex, involved in mRNA decapping |
physical |
1 |
1 |
1 |
Two-hybrid |
NNF1 |
YJR112W |
Essential component of the outer kinetochore MIND complex |
physical |
1 |
1 |
1 |
Two-hybrid |
HMS2 |
YJR147W |
Protein with similarity to heat shock transcription factors |
physical |
1 |
1 |
1 |
Two-hybrid |
FMP27 |
YLR454W |
Protein with structural similarity to lipid transport protein Vps13p |
physical |
1 |
1 |
1 |
Two-hybrid |
MDM1 |
YML104C |
PtdIns-3-P binding protein that tethers the ER to vacuoles at NVJs |
physical |
1 |
1 |
1 |
Two-hybrid |
STV1 |
YMR054W |
Subunit a of the vacuolar-ATPase V0 domain |
physical |
1 |
1 |
1 |
Two-hybrid |
END3 |
YNL084C |
EH domain-containing protein involved in endocytosis |
physical |
1 |
1 |
1 |
Two-hybrid |
CTF19 |
YPL018W |
Outer kinetochore protein, needed for accurate chromosome segregation |
physical |
1 |
1 |
1 |
Two-hybrid |
YPL216W |
YPL216W |
Putative protein of unknown function |
physical |
1 |
1 |
1 |
Two-hybrid |
SLK19 |
YOR195W |
Kinetochore-associated protein |
physical |
1 |
1 |
1 |
Two-hybrid |
SLK19 |
YOR195W |
Kinetochore-associated protein |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
EAF7 |
YNL136W |
Subunit of the NuA4 histone acetyltransferase complex |
physical |
1 |
1 |
1 |
Affinity Capture-Western |
CRM1 |
YGR218W |
Nuclear export factor, exportin |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
PUF2 |
YPR042C |
PUF family mRNA-binding protein |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
SPC97 |
YHR172W |
Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
DHH1 |
YDL160C |
Cytoplasmic DEAD-box helicase and mRNA decapping activator |
physical |
1 |
1 |
1 |
Affinity Capture-RNA |
MTQ2 |
YDR140W |
S-adenosylmethionine-dependent methyltransferase |
physical |
1 |
1 |
1 |
Affinity Capture-MS |
MOB1 |
YIL106W |
Component of the mitotic exit network |
physical |
1 |
1 |
1 |
Proximity Label-MS |
SPC72 |
YAL047C |
Gamma-tubulin small complex (gamma-TuSC) receptor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAR1 |
YNL188W |
Protein involved in karyogamy and spindle pole body duplication |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
KAR9 |
YPL269W |
Spindle positioning factor |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
SPO12 |
YHR152W |
Nucleolar protein of unknown function |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
CTF18 |
YMR078C |
Subunit of a complex with Ctf8p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
CTF8 |
YHR191C |
Subunit of a complex with Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
DCC1 |
YCL016C |
Subunit of a complex with Ctf8p and Ctf18p |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PAP2 |
YOL115W |
Non-canonical poly(A) polymerase |
genetic |
1 |
1 |
1 |
Synthetic Lethality |
SWE1 |
YJL187C |
Protein kinase that regulates the G2/M transition |
genetic |
1 |
1 |
1 |
Phenotypic Suppression |
ELG1 |
YOR144C |
Subunit of an alternative replication factor C complex |
genetic |
1 |
1 |
1 |
Dosage Rescue |
SCH9 |
YHR205W |
AGC family protein kinase |
genetic |
1 |
1 |
1 |
Synthetic Growth Defect |
PMA1 |
YGL008C |
Plasma membrane P2-type H+-ATPase |
genetic |
1 |
1 |
1 |
Negative Genetic |
AFI1 |
YOR129C |
Arf3p polarization-specific docking factor |
genetic |
1 |
1 |
1 |
Synthetic Rescue |
ADY4 |
YLR227C |
Structural component of the meiotic outer plaque |
physical |
1 |
1 |
1 |
Two-hybrid |
CLA4 |
YNL298W |
Cdc42p-activated signal transducing kinase |
genetic |
1 |
1 |
1 |
Dosage Growth Defect |